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UroGen Pharma Ltd. URGN R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://www.urogen.com
Company Profile ↓
$44.09
+119.24% 1Y
Mkt Cap$2.15B
P/E-21.72
P/B-18.41
52W High$50.29
52W Low$16.42
Book Value$-2.55
EPS (TTM)$-2.03

Company Overview

UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization of solutions for urothelial and specialty cancers. It offers RTGel, a novel proprietary polymeric biocompatible, reverse thermal gelation hydrogel technology; Mitomycin a generic drug used off-label as an adjuvant chemotherapy for the treatment of low-grade NMIBC after trans-urethral resection of bladder tumor; Zusduri, a sustained-release formulation of mitomycin for the treatment of non-muscle invasive bladder cancer (NMIBC); and Jelmyto for pyelocalyceal solutions. The company's lead product candidates are UGN-103, which is in phase 3 of clinical trial for intravesical solution; and UGN-104 that is in phase 3 of clinical trial for pyelocalyceal solution designed for the treatment of several forms of non-muscle invasive urothelial cancer that include low-grade upper tract urothelial cancer and low-grade intermediate risk NMIBC. It is also developing UGN-301, UGN-301+UGN 201, and UGN-301+gemcitabine that are in phase 1 of clinical trial for the treatment of high-grade NMIBC. The company has license agreement with Agenus Inc. to develop, make, use, sell, import, and commercialize products of Agenus for the treatment of cancers of the urinary tract via intravesical delivery; and licensing and supply agreement with medac Gesellschaft für klinische Spezialpräparate m.b.H. to develop UGN-103 and UGN-104. UroGen Pharma Ltd. was incorporated in 2004 and is headquartered in Princeton, New Jersey.

Why Investors Should Care

Strong Return on Equity

Generates a return on equity of 145.5%, reflecting efficient use of shareholder capital.

Steady Revenue Expansion

Revenue has grown at a 22.6% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $109.79M (+21.4% YoY); net profit $-153.49M.
  • Trailing 12 Months Year-on-year growth — revenue +199.2%.
  • 5-Year Trend Long-term compounding — revenue CAGR 22.6%.

Growth & Price Performance

Compounded Sales Growth

5 Years:22.61%
1 Year:199.20%

Stock Price Performance

1 Year:+119.24%
6 Months:+115.49%
3 Months:+64.21%
1 Month:-3.31%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 82% of range
$16.42 $50.29
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)48.38 · Neutral
Price Performance
1M-3.31%
3M+64.21%
6M+115.49%
1Y+119.24%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Strong return on equity of 145.5%.
  • Compounding revenue at 22.6% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-21.72
Industry PE
25.17
Forward P/E
20.48
PEG Ratio
-
Book Value
$-2.55
Price to Book
-18.41
P/S
12.12
EV/EBITDA
-35.93
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
22.61%
Profit 5Y
-
Revenue (YoY)
199.20%
Earnings (YoY)
-

Profitability & Returns

ROCE
-81.06%
ROE
145.53%
ROA
-18.06%
Profit Margin
-51.73%
Op Margin
0.15%
Gross Margin
90.84%
EPS (Latest Qtr)
$-
EPS (TTM)
$-2.03

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
3.18
Current Ratio
3.80
Debt
$196.13M
Total Assets
$252.59M
Current Assets
$237.46M
Working Capital
$186.83M

Ownership

Promoter Holding
3.48%
Chg in Prom Hold
-0.12%
FII / Inst Holding
100.10%
Chg in FII Hold
0.01%

Financial Snapshot

Enterprise Value
$2.15B
Total Revenue (TTM)
$188.73M
EBITDA
$-66.34M
Free Cash Flow
$-106.98M
Operating Cash Flow
$-158.92M
Shares Outstanding
48.72M
Gross Margin
90.84%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 URGN UroGen Pharma Ltd. R2KR3KPHARMA 44.09 -21.72 $2.15B 0.00% -81.06% 145.53% 22.61% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Dec 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue ----481.00K364.00K283.00K--18.00K---372.00K3.46M7.49M13.03M11.35M13.56M16.60M16.10M17.19M21.14M20.85M23.53M18.78M21.85M25.20M24.57M20.25M24.21M27.48M50.96M72.46M
Gross Profit ----51.00K46.00K-772.00K--18.00K---324.00K3.15M6.59M11.61M10.11M12.04M14.76M14.08M14.93M18.70M18.48M21.24M17.05M19.62M22.75M22.09M17.92M20.66M24.20M46.82M65.88M
Operating Income -3.54M-5.95M-303.00K-10.16M-13.64M-18.43M-21.09M-24.02M-22.43M-23.75M-23.45M-39.84M-38.56M-31.80M-29.12M-26.11M-22.82M-23.44M-21.96M-18.71M-18.09M-22.05M-15.38M-13.50M--25.74M-25.84M-17.55M--36.91M-41.45M-27.39M-20.26M111.00K
Net Income -3.42M-6.20M-298.00K-10.09M-13.38M-18.03M-20.53M-23.72M-21.44M-22.48M-22.25M-38.97M-37.79M-31.35M-28.82M-25.93M-26.22M-30.21M-28.39M-26.69M-25.83M-30.21M-24.14M-21.88M-26.02M-32.29M-33.40M-23.67M-37.51M-43.84M-49.94M-33.35M-23.57M-14.35M
R&D Expense -----8.27M9.57M-9.73M10.00M9.48M-16.59M8.11M10.21M10.51M12.12M11.92M12.70M12.64M13.09M12.50M11.58M10.23M-15.49M15.40M11.36M-19.87M18.91M14.01M15.60M17.34M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 17.53M8.16M1.13M18.00K11.80M48.04M64.36M82.71M90.40M109.79M
Gross Profit 17.50M7.56M-675.00K18.00K10.79M42.88M56.70M73.35M81.52M97.34M
Operating Income 798.00K-19.95M-77.18M-109.48M-126.74M-92.29M-79.04M-65.54M-96.78M-124.86M
Net Income -1.94M-20.00M-75.66M-105.15M-128.48M-110.82M-109.78M-102.24M-126.87M-153.49M
R&D Expense -18.70M36.93M49.30M47.31M47.64M52.91M45.61M57.15M67.11M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --75.55M103.56M202.39M122.00M119.75M135.62M178.31M285.71M200.46M
Total Equity 16.28M16.31M68.52M90.09M180.30M96.36M8.41M-89.36M-65.21M-8.80M-105.47M
Cash & Equivalents --37.00M101.32M49.69M52.86M44.36M55.41M95.00M171.99M110.75M
Long Term Debt ------097.54M98.55M121.73M122.21M
Total Liabilities --7.04M13.46M22.09M25.65M111.33M224.98M243.52M294.51M305.93M
Current Liabilities --7.04M13.46M19.48M21.44M22.38M23.92M31.21M45.95M46.42M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow 4.19M-9.57M-37.33M-71.02M-105.89M--87.56M-76.38M-96.77M-162.44M
Investing Cash Flow -719.00K-36.28M35.29M-145.59M93.24M-1.06M-953.00K-20.61M61.56M
Financing Cash Flow -9.00K61.59M66.42M165.25M16.53M-97.13M116.93M194.62M39.92M
Capital Expenditure -695.00K-271.00K-560.00K-325.00K-1.22M--254.00K-194.00K-295.00K-289.00K
Free Cash Flow 3.49M-9.84M-37.89M-71.34M-107.10M--87.81M-76.57M-97.06M-162.73M
Net Change in Cash ------10.63M39.60M77.24M-60.97M

Ratios (Annual)

Figures in %.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % 99.8%92.6%-59.8%100.0%91.4%89.3%88.1%88.7%90.2%88.7%
Operating Margin % 4.6%-244.5%-6,842.2%-608,211.1%-1,074.2%-192.1%-122.8%-79.2%-107.1%-113.7%
Net Margin % -11.1%-245.2%-6,707.2%-584,144.4%-1,088.9%-230.7%-170.6%-123.6%-140.4%-139.8%
ROE % -11.9%-29.2%-84.0%-58.3%-133.3%-1,317.2%122.9%156.8%1,441.3%145.5%
ROCE % --29.1%-85.7%-59.9%-126.0%-94.8%-70.8%-44.6%-40.4%-81.1%

Shareholding Pattern

Insiders
3.48%
Institutions
100.10%
Public Float
103.70%

Top Institutional Holders

#Holder% HeldSharesValue
1 RTW Investments LP 9.30% 4.54M $198.20M
2 Blackrock Inc. 6.55% 3.20M $139.65M
3 Morgan Stanley 5.27% 2.58M $112.38M
4 Kynam Capital Management, LP 4.98% 2.43M $106.18M
5 Jefferies Financial Group Inc. 4.50% 2.20M $95.95M
6 SG Americas Securities, LLC 4.20% 2.05M $89.55M
7 American Century Companies Inc 3.45% 1.69M $73.53M
8 Acorn Capital Advisors, LLC 3.42% 1.67M $72.99M
9 Point72 Asset Management, L.P. 3.12% 1.53M $66.54M
10 Frontier Capital Management Company LLC 3.09% 1.51M $65.80M

Analyst View

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Latest News

Recent headlines for URGN

Google News Wed, 02 Sep 2026

UroGen will speak at three investor events in September - Stock Titan

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Google News hu, 25 Jun 2026

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Google News Mon, 02 Mar 2026

$URGN stock is down 9% today. Here's what we see in our data. - quiverquant.com

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Google News Fri, 04 Sep 2026

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Google News Fri, 09 Jan 2026

UroGen Pharma Ltd. Ordinary Shares (URGN) Stock Price Today: $43.64 - Gotrade

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Google News hu, 07 May 2026

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URGN — Frequently Asked Questions

What is the current share price of UroGen Pharma Ltd. (URGN)?

As of 2026-09-07 16:24 PDT, UroGen Pharma Ltd. (URGN) trades at $44.09 on NasdaqGM. Its 52-week range is $16.42 to $50.29.

What is the market capitalisation of URGN?

UroGen Pharma Ltd. (URGN) has a market capitalisation of $2.15B on NasdaqGM.

What is the P/E ratio of URGN?

URGN trades at a trailing price-to-earnings (P/E) ratio of -21.72. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is -18.41.

What is the return on equity (ROE) of URGN?

URGN has a return on equity (ROE) of 145.53%. Its return on capital employed (ROCE) is -81.06%.

Is URGN a good stock to buy?

This page provides a data-driven analysis of UroGen Pharma Ltd. (URGN), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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