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Tyra Biosciences, Inc. TYRA R2K

Healthcare · Biotechnology · United States
https://tyra.bio
Company Profile ↓
$32.88
+201.37% 1Y
Mkt Cap$1.96B
P/E-15.08
P/B5.59
52W High$39.61
52W Low$10.10
Book Value$4.83
EPS (TTM)$-2.18

Company Overview

Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions. Its lead product candidate is FGFR3, which is in clinical trials for the treatment of patients with metastatic urothelial carcinoma and other solid tumors. The company is also developing TYRA-300 for skeletal conditions, including achondroplasia, hypochondroplasia, dysplasia, and other FGFR3-driven genetic syndromes; TYRA-200, a candidate in clinical trial for intrahepatic cholangiocarcinoma; and TYRA-430 for the treatment of hepatocellular carcinoma. Tyra Biosciences, Inc. was incorporated in 2018 and is headquartered in Carlsbad, California.

Growth & Price Performance

Stock Price Performance

1 Year:+201.37%
6 Months:+12.18%
3 Months:-7.69%
1 Month:+28.59%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 77% of range
$10.10 $39.61
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)59.14 · Neutral
Price Performance
1M+28.59%
3M-7.69%
6M+12.18%
1Y+201.37%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-15.08
Industry PE
25.41
Forward P/E
-11.64
PEG Ratio
-
Book Value
$4.83
Price to Book
5.59
P/S
-
EV/EBITDA
-8.62
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-50.19%
ROE
-36.87%
ROA
-23.64%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.64
EPS (TTM)
$-2.18

Balance Sheet & Liquidity

Debt/Equity
1.47
Quick Ratio
20.05
Current Ratio
20.49
Debt
$5.70M
Total Assets
$412.04M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
2.86%
Chg in Prom Hold
-
FII / Inst Holding
111.60%
Chg in FII Hold
-0.00%

Financial Snapshot

Enterprise Value
$1.96B
Total Revenue (TTM)
-
EBITDA
$-142.37M
Free Cash Flow
$-60.14M
Operating Cash Flow
$-102.25M
Shares Outstanding
59.47M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 TYRA Tyra Biosciences, Inc. R2K 32.88 -15.08 $1.96B 0.00% -50.19% -36.87% - -
2 LLY Eli Lilly and Company SPX 1,152.54 41.02 $1.03T 0.61% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 253.85 29.45 $611.07B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.78 119.40 $432.48B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 425.19 32.02 $386.13B 2.27% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 120.78 34.02 $298.31B 2.86% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 164.50 24.81 $255.12B 1.77% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 534.07 29.33 $198.47B 0.40% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 355.25 24.69 $191.73B 2.84% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Operating Income ---2.33M--4.21M-5.51M-6.64M-14.83M-15.43M-13.64M-14.33M-16.01M-23.96M-22.32M-23.53M-28.60M-31.85M-31.45M-32.94M-42.00M
Net Income -1.47M-1.84M-2.34M-3.69M-4.21M-5.51M-6.64M-14.83M-15.10M-12.51M-11.88M-13.27M-21.15M-18.19M-18.70M-24.02M-28.15M-28.10M-29.87M-39.30M
Diluted EPS ------2.43-0.72-0.36-0.36-0.30-0.28-0.31-0.49-0.35-0.32-0.41-0.47-0.47-0.50-0.64
R&D Expense --1.86M-3.52M4.38M5.48M9.64M12.05M10.91M10.41M12.16M19.27M17.20M18.00M22.70M24.96M24.31M25.47M33.47M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Income -9.30M-26.29M-58.93M-79.94M-104.18M-132.76M
Net Income -9.34M-26.29M-55.33M-69.13M-86.48M-119.95M
Diluted EPS --1.91-1.32-1.62-1.51-2.01
R&D Expense 7.20M20.64M43.01M62.52M80.08M102.93M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -16.01M306.70M266.18M225.86M363.56M282.61M
Total Equity -4.74M-13.64M301.74M257.83M204.26M343.15M259.18M
Cash & Equivalents -15.22M302.18M251.21M58.01M91.97M77.39M
Total Liabilities -2.00M4.96M8.35M21.59M20.41M23.43M
Current Liabilities -1.86M3.62M5.70M15.33M14.59M18.09M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -7.76M-23.75M-50.28M-50.14M-69.77M-95.14M
Investing Cash Flow -312.00K-645.00K-559.00K-144.60M-98.40M72.46M
Financing Cash Flow 23.43M311.35M632.00K1.54M202.14M8.10M
Capital Expenditure -312.00K-661.00K-559.00K-770.00K-664.00K-141.00K
Free Cash Flow -8.07M-24.41M-50.84M-50.91M-70.44M-95.28M

Ratios (Annual)

Figures in %.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ------
Operating Margin % ------
Net Margin % ------
ROE % 68.5%-8.7%-21.5%-33.8%-25.2%-46.3%
ROCE % -65.7%-8.7%-22.6%-38.0%-29.9%-50.2%

Shareholding Pattern

Insiders
2.86%
Institutions
111.60%
Public Float
114.88%

Top Institutional Holders

#Holder% HeldSharesValue
1 RA Capital Management, L.P. 20.51% 12.20M $374.50M
2 FMR, LLC 13.03% 7.75M $237.85M
3 Nextech Invest, Ltd. 6.82% 4.06M $124.51M
4 Janus Henderson Group PLC 6.54% 3.89M $119.44M
5 Alta Partners Management Company, L.P. 6.43% 3.82M $117.38M
6 Farallon Capital Management LLC 6.02% 3.58M $109.93M
7 TCG Crossover Management, LLC 5.46% 3.25M $99.74M
8 Commodore Capital Lp 4.16% 2.48M $75.98M
9 Blackrock Inc. 3.73% 2.22M $68.09M
10 Paradigm Biocapital Advisors LP 3.46% 2.05M $63.09M

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for TYRA

Google News ue, 30 Jun 2026

Is Tyra Biosciences, Inc. (TYRA) Stock a Biotech Opportunity Ahead of Key SURF302 Trial Data? - Yahoo Finance

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Google News Sat, 11 Jul 2026

Price to earnings forward of Tyra Biosciences, Inc. – NASDAQ:TYRA - TradingView

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Google News Fri, 10 Jul 2026

Behavioral Patterns of TYRA and Institutional Flows - Stock Traders Daily

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Google News Mon, 01 Jun 2026

$TYRA stock is down 9% today. Here's what we see in our data. - Quiver Quantitative

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Google News Wed, 13 May 2026

Tyra Biosciences Reports First Quarter 2026 Financial Results and Recent Highlights - PR Newswire

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Google News hu, 25 Jun 2026

Tyra Biosciences (TYRA) Gains Attention On Phase II Results, Is The Upside Already Priced In? - simplywall.st

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TYRA — Frequently Asked Questions

What is the current share price of Tyra Biosciences, Inc. (TYRA)?

As of 2026-07-14 21:23 PDT, Tyra Biosciences, Inc. (TYRA) trades at $32.88 on NasdaqGS. Its 52-week range is $10.10 to $39.61.

What is the market capitalisation of TYRA?

Tyra Biosciences, Inc. (TYRA) has a market capitalisation of $1.96B on NasdaqGS.

What is the P/E ratio of TYRA?

TYRA trades at a trailing price-to-earnings (P/E) ratio of -15.08. The industry average P/E is 25.41. Its price-to-book (P/B) ratio is 5.59.

What is the return on equity (ROE) of TYRA?

TYRA has a return on equity (ROE) of -36.87%. Its return on capital employed (ROCE) is -50.19%.

Is TYRA a good stock to buy?

This page provides a data-driven analysis of Tyra Biosciences, Inc. (TYRA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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