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Rapport Therapeutics, Inc. RAPP R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://www.rapportrx.com
Company Profile ↓
$45.77
+193.40% 1Y
Mkt Cap$2.20B
P/E-15.11
P/B5.16
52W High$52.50
52W Low$14.24
Book Value$8.82
EPS (TTM)$-3.03

Company Overview

Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. It also develops nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and migraine; and a9a10 nAChR for the treatment of hearing/vestibular disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.

Growth & Price Performance

Stock Price Performance

1 Year:+193.40%
6 Months:+51.36%
3 Months:+26.79%
1 Month:-1.25%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 82% of range
$14.24 $52.50
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)45.30 · Neutral
Price Performance
1M-1.25%
3M+26.79%
6M+51.36%
1Y+193.40%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-15.11
Industry PE
25.17
Forward P/E
-9.44
PEG Ratio
-
Book Value
$8.82
Price to Book
5.16
P/S
109.13
EV/EBITDA
-11.51
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-25.36%
ROE
-39.96%
ROA
-25.78%
Profit Margin
0.00%
Op Margin
-
Gross Margin
-
EPS (Latest Qtr)
$-1.19
EPS (TTM)
$-3.03

Balance Sheet & Liquidity

Debt/Equity
2.39
Quick Ratio
15.35
Current Ratio
15.72
Debt
$10.11M
Total Assets
$458.98M
Current Assets
$484.69M
Working Capital
$479.51M

Ownership

Promoter Holding
3.92%
Chg in Prom Hold
-0.04%
FII / Inst Holding
108.71%
Chg in FII Hold
-0.00%

Financial Snapshot

Enterprise Value
$2.20B
Total Revenue (TTM)
$20.00M
EBITDA
$-152.56M
Free Cash Flow
$-56.02M
Operating Cash Flow
$-96.68M
Shares Outstanding
47.98M
Gross Margin
-
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 RAPP Rapport Therapeutics, Inc. R2KR3KPHARMA 45.77 -15.11 $2.20B 0.00% -25.36% -39.96% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue ------0--20.00M0
Operating Income --6.63M-9.56M-17.09M-20.80M-21.64M-27.11M-29.50M-29.99M-24.21M-60.81M
Net Income -6.15M-6.41M-8.71M-22.67M-18.12M-17.54M-24.06M-26.73M-26.93M-19.86M-56.62M
Diluted EPS --4.45-5.70-11.07-1.70-0.50-0.68-0.75-0.71-0.42-1.19
R&D Expense -4.72M7.58M12.50M15.69M15.54M19.57M22.68M22.28M32.72M51.41M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2023Dec 2024Dec 2025
Operating Income -36.18M-83.06M-125.10M
Net Income -34.79M-78.31M-111.48M
Diluted EPS -23.10-3.78-2.86
R&D Expense 28.00M60.94M94.79M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets 31.60M155.42M314.93M512.43M
Current Assets 31.27M150.87M309.80M498.56M
Cash & Equivalents 31.16M70.17M56.80M52.65M
Inventory ----
Receivables ----
Total Liabilities 41.66M181.06M9.51M27.78M
Current Liabilities 1.66M8.80M8.77M19.05M
Long Term Debt ----
Total Debt 02.15M1.48M11.48M
Total Equity -10.06M-25.63M305.43M484.65M
Shares Outstanding 35.38M35.38M36.58M47.77M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2023Dec 2024Dec 2025
Operating Cash Flow -27.18M-64.83M-87.47M
Investing Cash Flow -78.86M-170.14M-187.47M
Financing Cash Flow 145.14M221.62M270.79M
Capital Expenditure -1.64M-2.40M-616.00K
Free Cash Flow -28.82M-67.23M-88.09M
Net Change in Cash 39.09M-13.34M-4.16M

Ratios (Annual)

Figures in %.

Metric Dec 2023Dec 2024Dec 2025
Gross Margin % ---
Operating Margin % ---
Net Margin % ---
ROE % 135.7%-25.6%-23.0%
ROCE % -24.7%-27.1%-25.4%

Shareholding Pattern

Insiders
3.92%
Institutions
108.71%
Public Float
113.14%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 14.95% 7.17M $349.82M
2 Trv Gp V, LLC 13.09% 6.28M $306.30M
3 Arch Venture Management, Llc 7.77% 3.73M $181.85M
4 Capital International Investors 6.09% 2.92M $142.50M
5 Goldman Sachs Group Inc 6.07% 2.91M $141.94M
6 Blackrock Inc. 5.63% 2.70M $131.67M
7 Cormorant Asset Management, LP 5.54% 2.66M $129.61M
8 Sofinnova Investments, Inc. 3.97% 1.90M $92.88M
9 Johnson & Johnson 3.72% 1.78M $87.03M
10 Polar Capital Holdings PLC 3.35% 1.61M $78.45M

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for RAPP

Yahoo Finance Wed, 02 Sep 2026

Rapport Therapeutics to Participate in Upcoming Investor Conferences

BOSTON and SAN DIEGO, Sept. 02, 2026 (GLOBE NEWSWIRE) -- Rapport Therapeutics, Inc. (Nasdaq: RAPP) (“Rapport” or the “Company”), a clinical-stage biotechnology company dedicated to the discovery and development of small molecule precision m…

Yahoo Finance Mon, 24 Aug 2026

Rapport Therapeutics to Host Virtual KOL Event on the Unmet Need in Bipolar Mania and the RAP-219 Clinical Program

BOSTON and SAN DIEGO, Aug. 24, 2026 (GLOBE NEWSWIRE) -- Rapport Therapeutics, Inc. (Nasdaq: RAPP) (“Rapport” or the “Company”), a clinical-stage biotechnology company dedicated to the discovery and development of small molecule precision me…

Yahoo Finance Wed, 05 Aug 2026

Rapport Therapeutics Reports Second Quarter 2026 Financials and Provides Business Update

RAP-219 Phase 3 program in focal onset seizures initiated, with FOCUS 1 and FOCUS 2 trials enrolling patients RAP-219 Phase 2 trial in bipolar mania on track for topline results in October 2026 Pipeline continues to advance, including the R…

Yahoo Finance Sun, 12 Jul 2026

What Does the Sale of Rapport Therapeutics Stock Worth Over $400,000 by the Chief Operating Officer Mean for Investors?

This clinical-stage biotech focused on CNS disorders reported a notable insider sale amid a year of exceptional stock appreciation.

Yahoo Finance Mon, 08 Jun 2026

Is Rapport Therapeutics (RAPP) Using RAP-219 To Redefine Its Broader Neuroscience Investment Narrative?

In late May 2026, analysts BTIG and Truist highlighted Rapport Therapeutics’ RAP-219 program after the company reported progress toward Phase 3 trials, supported by earlier Phase 2a follow-up data. An interesting angle is how RAP-219’s dual…

Yahoo Finance Fri, 05 Jun 2026

BTIG Raises its Price Target on Rapport Therapeutics (RAPP)

Rapport Therapeutics, Inc. (NASDAQ:RAPP) is one of the 10 Stocks That Have the Potential to Rise 1000%. On May 21, 2026, BTIG raised the firm’s price target on Rapport Therapeutics, Inc. (NASDAQ:RAPP) to $65 from $53 and maintained a Buy ra…

RAPP — Frequently Asked Questions

What is the current share price of Rapport Therapeutics, Inc. (RAPP)?

As of 2026-09-07 16:24 PDT, Rapport Therapeutics, Inc. (RAPP) trades at $45.77 on NasdaqGM. Its 52-week range is $14.24 to $52.50.

What is the market capitalisation of RAPP?

Rapport Therapeutics, Inc. (RAPP) has a market capitalisation of $2.20B on NasdaqGM.

What is the P/E ratio of RAPP?

RAPP trades at a trailing price-to-earnings (P/E) ratio of -15.11. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 5.16.

What is the return on equity (ROE) of RAPP?

RAPP has a return on equity (ROE) of -39.96%. Its return on capital employed (ROCE) is -25.36%.

Is RAPP a good stock to buy?

This page provides a data-driven analysis of Rapport Therapeutics, Inc. (RAPP), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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