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Rapport Therapeutics, Inc. RAPP R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://www.rapportrx.com
Company Profile ↓
$25.93
+66.22% 1Y
Mkt Cap$1.24B
P/E-8.56
P/B4.59
52W High$52.50
52W Low$14.24
Book Value$8.82
EPS (TTM)$-3.03

Company Overview

Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. The company's lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. It also develops nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and migraine; and a9a10 nAChR for the treatment of hearing/vestibular disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.

Growth & Price Performance

Stock Price Performance

1 Year:+66.22%
6 Months:-29.08%
3 Months:-38.45%
1 Month:-23.35%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 31% of range
$14.24 $52.50
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)30.49 · Neutral
Price Performance
1M-23.35%
3M-38.45%
6M-29.08%
1Y+66.22%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Trading 50.6% below its 52-week high.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-8.56
Industry PE
25.45
Forward P/E
-4.96
PEG Ratio
-
Book Value
$8.82
Price to Book
4.59
P/S
97.04
EV/EBITDA
-9.91
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-25.36%
ROE
-39.96%
ROA
-25.78%
Profit Margin
0.00%
Op Margin
-
Gross Margin
-
EPS (Latest Qtr)
$-1.19
EPS (TTM)
$-3.03

Balance Sheet & Liquidity

Debt/Equity
2.39
Quick Ratio
15.35
Current Ratio
15.72
Debt
$10.11M
Total Assets
$458.98M
Current Assets
$484.69M
Working Capital
$479.51M

Ownership

Promoter Holding
3.90%
Chg in Prom Hold
-0.01%
FII / Inst Holding
109.01%
Chg in FII Hold
0.13%

Financial Snapshot

Enterprise Value
$1.24B
Total Revenue (TTM)
$20.00M
EBITDA
$-152.56M
Free Cash Flow
$-56.02M
Operating Cash Flow
$-96.68M
Shares Outstanding
47.98M
Gross Margin
-
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 RAPP Rapport Therapeutics, Inc. R2KR3KPHARMA 25.93 -8.56 $1.24B 0.00% -25.36% -39.96% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,273.46 42.83 $1.14T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 263.81 30.60 $635.76B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 285.64 80.69 $504.76B 2.54% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 418.09 26.85 $375.28B 2.47% 9.74% 14.15% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPXR3KPHARMA 145.27 116.22 $358.41B 2.31% - 6.96% 5.64% 10.01%
7 NVS Novartis AG PHARMA 151.12 22.83 $287.24B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 171.49 25.63 $265.96B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 673.82 36.30 $249.14B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue ------0--20.00M0
Operating Income --6.63M-9.56M-17.09M-20.80M-21.64M-27.11M-29.50M-29.99M-24.21M-60.81M
Net Income -6.15M-6.41M-8.71M-22.67M-18.12M-17.54M-24.06M-26.73M-26.93M-19.86M-56.62M
Diluted EPS --4.45-5.70-11.07-1.70-0.50-0.68-0.75-0.71-0.42-1.19
R&D Expense -4.72M7.58M12.50M15.69M15.54M19.57M22.68M22.28M32.72M51.41M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2023Dec 2024Dec 2025
Operating Income -36.18M-83.06M-125.10M
Net Income -34.79M-78.31M-111.48M
Diluted EPS -23.10-3.78-2.86
R&D Expense 28.00M60.94M94.79M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets 31.60M155.42M314.93M512.43M
Current Assets 31.27M150.87M309.80M498.56M
Cash & Equivalents 31.16M70.17M56.80M52.65M
Inventory ----
Receivables ----
Total Liabilities 41.66M181.06M9.51M27.78M
Current Liabilities 1.66M8.80M8.77M19.05M
Long Term Debt ----
Total Debt 02.15M1.48M11.48M
Total Equity -10.06M-25.63M305.43M484.65M
Shares Outstanding 35.38M35.38M36.58M47.77M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2023Dec 2024Dec 2025
Operating Cash Flow -27.18M-64.83M-87.47M
Investing Cash Flow -78.86M-170.14M-187.47M
Financing Cash Flow 145.14M221.62M270.79M
Capital Expenditure -1.64M-2.40M-616.00K
Free Cash Flow -28.82M-67.23M-88.09M
Net Change in Cash 39.09M-13.34M-4.16M

Ratios (Annual)

Figures in %.

Metric Dec 2023Dec 2024Dec 2025
Gross Margin % ---
Operating Margin % ---
Net Margin % ---
ROE % 135.7%-25.6%-23.0%
ROCE % -24.7%-27.1%-25.4%

Shareholding Pattern

Insiders
3.90%
Institutions
109.01%
Public Float
113.43%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 14.95% 7.17M $219.85M
2 Trv Gp V, LLC 13.09% 6.28M $192.50M
3 Arch Venture Management, Llc 7.77% 3.73M $114.29M
4 Capital International Investors 6.09% 2.92M $89.56M
5 Goldman Sachs Group Inc 6.07% 2.91M $89.21M
6 Blackrock Inc. 5.63% 2.70M $82.75M
7 Cormorant Asset Management, LP 5.54% 2.66M $81.45M
8 Sofinnova Investments, Inc. 3.97% 1.90M $58.37M
9 Johnson & Johnson 3.72% 1.78M $54.70M
10 Polar Capital Holdings PLC 3.35% 1.61M $49.30M

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for RAPP

Google News Fri, 23 Oct 2026

Rapport Therapeutics, Inc. RAPP Stock Forecast & Price Target - Yahoo Finance

<a href="https://news.google.com/rss/articles/CBMiigFBVV95cUxNVzZtSDZnalBNY1VXTFZadXlzZl84MDFlbzRzT1Rpb2o3OEFIekw5a2lHcFdoMmNkdHY5YzMySGNZX1hRSXRGMmdjc1ZnMmhLZXRHdEg2eXZSS0FyNWVSUGh4dnFUQWpDTEhRU1gySkt4c012TDNrQ1h3RHhFbkhYOFpqdThPN2pJYUE?oc…

Google News ue, 20 Oct 2026

RAPP Stock Tempers Premarket Gains On Concerns Over Higher Discontinuation Rates In Bipolar Mania Study - Stocktwits

<a href="https://news.google.com/rss/articles/CBMi-wFBVV95cUxQZGVHZ0VDUDlYNW5PTlE5WjF6eXV1MFNBeDJvSGdFSkNyR3FXY2hLU2c5OGx6eG9vcHQ2SnhRbnRncHlRaEpHVUpqUHJ4TUVMWFotUUNVYnlLRDNRdUhSQXdYR2VIdE9oUnZ0LVd2RGt1elNzaGdfRUhXZkpXR1FoSkJEdVFzWUVUMzBCVU…

Google News ue, 20 Oct 2026

RAPP Stock Tempers Premarket Gains On Concerns Over Higher Discontinuation Rates In Bipolar Mania Study - TradingView

<a href="https://news.google.com/rss/articles/CBMi9gFBVV95cUxOMVNfRjNwZVV4eXdzQXQ0QkxFLUxIUzNobkh4OWdGQ0NiRFg3d3J3ZlVKN3BIYUVtQ0UzYjlCQWM3VnlaRU5yYXBhRldoMlJZTElWd1RZeFpUT2tYVE1DX0owTnFHZi0xNmhpQXRnUk9JMFNnTE9HZnJSZ1p3aDc3MF93dEVhUGkxOFhjTm…

Google News ue, 20 Oct 2026

Rapport Therapeutics (RAPP) Stock Seems Pricey Following A 29% Monthly Slide - Yahoo Finance

<a href="https://news.google.com/rss/articles/CBMipAFBVV95cUxOWW1nR0dlUUM4ckVkR2lqQnlQSWgxWG1mOGlpeDNfVmVsSTdWaThrNXNMWTlKaV8xcllUYnBSMTJIOHNVVDRQQW4yN3liNmN0R0JxTHpwbGZLSmsySjlyMTRxOS1EeTZRN0lpYnd3M1FPUWJ1M2hDWjV3cy1JbHdrakZIWTh3MC1CVEh2dX…

Google News ue, 20 Oct 2026

Why Is Rapport Therapeutics Stock Trading Higher Today? - Benzinga

<a href="https://news.google.com/rss/articles/CBMitgFBVV95cUxQN0FFOTZmbUZEeDNnVWV5QVMyWHgzcmczWmZaWHNGanpNZXlHcG9iblhaTEgwZnBRQk56enNNV0FULWJRQUdROFZUeFZqYTZMNHVtdnRHUnBvWGtZRUxLZW51OFltRHpHT19MMDJfczVOSUExTjdCWFpLcGhwUThKVkRlRjJIal91X3hHSV…

Google News ue, 20 Oct 2026

Can This Small Biotech Enter A $4.3 Billion AbbVie Market? Rapport Rises - Investor's Business Daily

<a href="https://news.google.com/rss/articles/CBMikAFBVV95cUxPRklTWHJCcFJjNzYxdWN6aDFPVjVxOHJxZnVxajREdTc4UzR2M0YtZEhNTkVmamdNcDhzckZGT2VDbk10eGkwR2VINVRUcUJGLTBiRFo0ZWhWNkkwRHZJamkxdTlpODY0aTItZGJPeFJkd1VHb0QxSlF2bzFEUUJ4RnlWYVk2bm5oZHBKRk…

RAPP — Frequently Asked Questions

What is the current share price of Rapport Therapeutics, Inc. (RAPP)?

As of 2026-10-23 16:27 PDT, Rapport Therapeutics, Inc. (RAPP) trades at $25.93 on NasdaqGM. Its 52-week range is $14.24 to $52.50.

What is the market capitalisation of RAPP?

Rapport Therapeutics, Inc. (RAPP) has a market capitalisation of $1.24B on NasdaqGM.

What is the P/E ratio of RAPP?

RAPP trades at a trailing price-to-earnings (P/E) ratio of -8.56. The industry average P/E is 25.45. Its price-to-book (P/B) ratio is 4.59.

What is the return on equity (ROE) of RAPP?

RAPP has a return on equity (ROE) of -39.96%. Its return on capital employed (ROCE) is -25.36%.

Is RAPP a good stock to buy?

This page provides a data-driven analysis of Rapport Therapeutics, Inc. (RAPP), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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