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$3.13
+184.55% 1Y
Mkt Cap$196.22M
P/E-2.45
P/B3.67
52W High$5.34
52W Low$1.04
Book Value$0.85
EPS (TTM)$-1.28

Company Overview

PYXS (PYXS) is a publicly traded company listed on with a market capitalization of $196.22M. The valuation, growth and price-trend signals below summarize what matters most to investors and traders evaluating the stock.

Why Investors Should Care

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.35.

Recent Developments

  • Dec 2025 Revenue of $13.86M (-14.2% YoY); net profit $-79.62M.
  • Trailing 12 Months Year-on-year growth — revenue -14.2%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-
1 Year:-14.17%

Stock Price Performance

1 Year:+184.55%
6 Months:+110.07%
3 Months:+71.04%
1 Month:+1.95%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 49% of range
$1.04 $5.34
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)62.74 · Neutral
Price Performance
1M+1.95%
3M+71.04%
6M+110.07%
1Y+184.55%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 41.4% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-2.45
Industry PE
-
Forward P/E
-
PEG Ratio
-
Book Value
$0.85
Price to Book
3.67
P/S
-
EV/EBITDA
-
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-14.17%
Earnings (YoY)
-

Profitability & Returns

ROCE
-119.93%
ROE
-149.08%
ROA
-87.00%
Profit Margin
-
Op Margin
-
Gross Margin
82.77%
EPS (Latest Qtr)
$-0.37
EPS (TTM)
$-1.28

Balance Sheet & Liquidity

Debt/Equity
0.35
Quick Ratio
-
Current Ratio
3.41
Debt
$18.67M
Total Assets
$64.30M
Current Assets
$45.57M
Working Capital
$50.97M

Ownership

Promoter Holding
13.60%
Chg in Prom Hold
0.00%
FII / Inst Holding
42.83%
Chg in FII Hold
0.00%

Financial Snapshot

Enterprise Value
-
Total Revenue (TTM)
$13.86M
EBITDA
$-79.91M
Free Cash Flow
$-63.51M
Operating Cash Flow
$-63.50M
Shares Outstanding
62.69M
Gross Margin
82.77%
Payout Ratio
-
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue ------------16.15M---02.82M011.04M0
Cost of Revenue ---------------00002.39M-
Gross Profit ---------------002.82M08.65M-
Operating Expenses ----------------22.91M22.57M23.46M26.95M24.36M
Operating Income ---3.19M-35.73M-5.94M-11.62M-31.39M-25.73M-28.39M-20.95M-18.12M-25.35M-5.61M-20.03M-23.75M--22.91M-19.75M-23.46M-18.30M-24.36M
EBITDA -----------------22.36M-19.21M-22.93M-15.40M-23.90M
Interest Expense ---------------------
Pretax Income -----------------21.16M-18.07M-22.00M-17.00M-23.27M
Tax Provision -----------------283.00K01.10M-
Net Income -1.96M-3.10M-3.19M-36.83M-8.15M-14.18M-31.38M-25.56M-27.67M-19.24M-15.90M-23.05M-3.26M-17.30M-21.20M--21.16M-18.35M-22.00M-18.11M-23.27M
Diluted EPS -----5.54-8.96-0.97-0.79-0.85-0.54-0.41-0.56-0.06-0.29-0.35--0.35-0.30-0.35--0.37
R&D Expense --2.42M32.77M3.21M7.85M20.07M17.17M19.03M11.90M11.39M14.69M13.03M13.95M17.74M-17.04M17.13M17.81M-19.98M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue --0016.15M13.86M
Cost of Revenue ---0475.00K2.39M
Gross Profit ---015.67M11.47M
Operating Expenses --123.48M82.20M84.17M95.89M
Operating Income -12.89M--123.48M-82.20M-68.50M-84.42M
EBITDA ---122.77M-80.27M-65.51M-79.91M
Interest Expense ------
Pretax Income ---120.72M-73.79M-79.50M-78.23M
Tax Provision ---0-2.16M1.39M
Net Income -12.83M--120.72M-73.79M-77.33M-79.62M
Diluted EPS ---3.65-1.85-1.32-1.28
R&D Expense 9.05M51.05M86.13M49.59M58.75M73.70M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -10.15M-211.38M173.73M157.18M91.52M
Current Assets ---186.61M124.60M132.44M72.11M
Cash & Equivalents -8.08M-179.29M9.66M19.47M15.42M
Inventory -------
Receivables ---598.00K21.00K0700.00K
Total Liabilities -3.85M-50.55M48.02M36.43M38.11M
Current Liabilities -3.69M-31.63M25.76M17.68M21.13M
Long Term Debt -------
Total Debt ---18.92M21.33M20.20M18.67M
Total Equity -2.87M-15.64M-160.82M125.70M120.75M53.41M
Shares Outstanding ---34.96M44.75M59.97M62.69M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -10.08M--89.33M-70.71M-57.67M-63.50M
Investing Cash Flow -1.48M--6.40M-104.85M8.15M58.86M
Financing Cash Flow 35.00K-183.00K5.93M59.33M594.00K
Capital Expenditure -1.48M--6.40M-6.73M-237.00K-9.00K
Free Cash Flow -11.57M--95.73M-77.44M-57.91M-63.51M
Net Change in Cash ---95.55M-169.63M9.81M-4.05M

Ratios (Annual)

Figures in %.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ----97.1%82.8%
Operating Margin % -----424.2%-609.2%
Net Margin % -----478.9%-574.5%
ROE % 82.0%--75.1%-58.7%-64.0%-149.1%
ROCE % -199.5%--68.7%-55.6%-49.1%-119.9%

Shareholding Pattern

Insiders
13.60%
Institutions
42.83%
Public Float
49.57%

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for PYXS

Yahoo Finance ue, 30 Jun 2026

Pyxis Oncology Secures Up to $114 Million Private Placement

Pyxis Oncology (PYXS) said Tuesday it entered into definitive agreements for a private placement exp

Yahoo Finance ue, 30 Jun 2026

Pyxis Oncology Announces Up to $114 Million Private Placement Financing to Advance MICVO Through Key Clinical Milestones

Expected to extend cash runway into the second quarter of 2027, supporting additional follow-up for 2L+ R/M HNSCC patients treated with MICVO at or below a dose cap Company now expects updated Phase 1 monotherapy data in Fall 2026 and updat…

Yahoo Finance Wed, 10 Jun 2026

Analysts See Nearly 3X Upside in Pyxis Oncology (PYXS)

While Pyxis Oncology, Inc. (NASDAQ:PYXS) has gained 54.78% year-to-date, analysts continue to see 293.30% upside, helping it secure a spot on our list of hot biotech stocks under $5 to buy. That analyst conviction is rooted in a busy clinic…

Yahoo Finance hu, 14 May 2026

Pyxis Oncology Reports First Quarter 2026 Financial Results and Advances MICVO Toward Key 2026 Clinical Milestones

Updated micvotabart pelidotin (MICVO) Phase 1 monotherapy data in 2L+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) on track for mid-year 2026; update to include analyses focused on patients treated at or below a do…

Yahoo Finance Wed, 13 May 2026

Pyxis Oncology to Participate in Upcoming Investor Conferences

BOSTON, May 13, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that management will participate in the following…

Yahoo Finance ue, 12 May 2026

Creative Global Technology Holdings And 2 Other Promising Penny Stocks

Over the last 7 days, the U.S. market has risen by 2.6%, and in the past year, it has climbed an impressive 26%, with earnings forecasted to grow by 17% annually. In such a robust market environment, identifying stocks with solid financials…

PYXS — Frequently Asked Questions

What is the current share price of PYXS?

As of 2026-08-05 17:25 PDT, PYXS trades at $3.13 on NASDAQ/NYSE. Its 52-week range is $1.04 to $5.34.

What is the market capitalisation of PYXS?

PYXS has a market capitalisation of $196.22M on NASDAQ/NYSE.

What is the P/E ratio of PYXS?

PYXS trades at a trailing price-to-earnings (P/E) ratio of -2.45. Its price-to-book (P/B) ratio is 3.67.

What is the return on equity (ROE) of PYXS?

PYXS has a return on equity (ROE) of -149.08%. Its return on capital employed (ROCE) is -119.93%.

Is PYXS a good stock to buy?

This page provides a data-driven analysis of PYXS, including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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