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Pulse Biosciences, Inc. PLSE R2KR3KPHARMA

Healthcare · Medical Instruments & Supplies · United States
https://www.pulsebiosciences.com
Company Profile ↓
$53.24
+217.09% 1Y
Mkt Cap$3.80B
P/E-48.40
P/B43.63
52W High$54.71
52W Low$12.66
Book Value$0.97
EPS (TTM)$-1.10

Company Overview

Pulse Biosciences, Inc. operates as a novel bioelectric medicine company. It offers nPulse System, a novel Nanosecond Pulsed-Field Ablation delivery platform to treat benign lesions of the skin; nPulse Vybrance Percutaneous Electrode system for soft tissue ablation in surgical setting; nPulse Cardiac Surgical Clamp designed for use in surgical treatment of atrial fibrillation (AF); nPulse Cardiac Catheter System designed to provide a circumferential, or circular, ablation in a single treatment cycle; and nPulse Console, a software-enabled console-based platform designed to accommodate the clinical workflow preferred by physicians. The company was formerly known as Electroblate, Inc. and changed its name to Pulse Biosciences, Inc. in December 2015. Pulse Biosciences, Inc. was incorporated in 2014 and is headquartered in Miami, Florida.

Why Investors Should Care

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.11.

Growth & Price Performance

Stock Price Performance

1 Year:+217.09%
6 Months:+193.50%
3 Months:+110.19%
1 Month:+39.23%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 97% of range
$12.66 $54.71
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)71.99 · Overbought
Price Performance
1M+39.23%
3M+110.19%
6M+193.50%
1Y+217.09%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-48.40
Industry PE
25.17
Forward P/E
-48.84
PEG Ratio
-
Book Value
$0.97
Price to Book
43.63
P/S
4,027.69
EV/EBITDA
-33.84
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-88.83%
ROE
-80.72%
ROA
-45.03%
Profit Margin
0.00%
Op Margin
-
Gross Margin
-21.04%
EPS (Latest Qtr)
$-0.27
EPS (TTM)
$-1.10

Balance Sheet & Liquidity

Debt/Equity
0.11
Quick Ratio
6.99
Current Ratio
7.26
Debt
$7.16M
Total Assets
$115.56M
Current Assets
$83.42M
Working Capital
$75.50M

Ownership

Promoter Holding
71.04%
Chg in Prom Hold
-2.17%
FII / Inst Holding
15.38%
Chg in FII Hold
-0.00%

Financial Snapshot

Enterprise Value
$3.80B
Total Revenue (TTM)
$751.00K
EBITDA
$-76.40M
Free Cash Flow
$-29.08M
Operating Cash Flow
$-55.20M
Shares Outstanding
71.32M
Gross Margin
-21.04%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 PLSE Pulse Biosciences, Inc. R2KR3KPHARMA 53.24 -48.40 $3.80B 0.00% -88.83% -80.72% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue -----------------------574.00K444.00K265.00K000000--0086.00K264.00K401.00K434.00K
Cost of Revenue ----------------------------------0-279.00K260.00K370.00K-
Gross Profit ----------------------------------0--193.00K4.00K31.00K-
Operating Expenses ----------------------------------18.04M20.27M20.17M18.26M19.18M-
Operating Income -1.23M-1.53M-1.68M-2.26M-2.77M-2.81M-3.20M-6.18M-7.49M-8.70M-8.67M-9.16M-10.76M-8.95M-10.08M-11.36M-11.75M-13.79M---12.90M-18.52M-14.81M-14.27M-17.27M-14.01M-18.02M-9.56M-10.23M-11.25M-10.62M-11.73M---18.04M-20.27M-20.37M-18.25M-19.15M-25.27M
EBITDA -----------------------------------17.76M-20.00M-20.11M-17.99M-18.89M-
Interest Expense ----------------------------------------
Pretax Income -----------------------------------16.80M-19.17M-19.39M-17.43M-18.58M-
Tax Provision --------------------------------0000----
Net Income -751.00K-1.02M-1.68M-2.26M-2.77M-2.81M-3.20M-6.18M-7.49M-8.70M-8.67M-9.16M-10.76M-8.95M-10.08M-11.36M-11.75M-13.79M-11.87M-11.33M-12.90M-18.64M-15.32M-14.28M-17.27M-14.00M-18.04M-9.80M-9.91M-10.57M-10.14M-11.38M---16.80M-19.17M-19.39M-17.43M-18.58M-24.66M
Diluted EPS -----------------------0.58-0.48--0.44-0.49--------0.25-0.28-0.29-0.26-0.27-
R&D Expense 659.00K951.00K874.00K1.43M1.55M1.65M1.73M2.13M2.92M2.86M3.17M3.96M5.04M5.08M5.84M6.34M6.19M6.59M6.18M5.87M6.97M9.06M7.46M6.46M6.77M5.46M4.52M5.83M6.70M7.47M6.74M7.23M7.70M-10.31M12.09M11.39M-12.59M16.98M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -----0-700.00K00350.00K
Cost of Revenue -------11.94M00539.00K
Gross Profit --------11.24M00-189.00K
Operating Expenses -------46.81M43.57M56.26M76.75M
Operating Income -4.47M-9.52M-25.57M-37.55M-47.95M-49.97M--58.06M-43.57M-56.26M-76.94M
EBITDA --------56.70M-42.37M-55.08M-75.87M
Interest Expense -----------
Pretax Income --------58.51M-42.21M-53.59M-72.78M
Tax Provision ------0000-
Net Income -2.81M-9.52M-25.57M-37.55M-46.97M-49.85M--58.51M-42.21M-53.59M-72.78M
Diluted EPS --------1.69-0.85-0.92-1.08
R&D Expense 2.18M5.51M9.65M17.25M24.96M26.44M28.64M20.84M27.80M32.34M44.72M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -14.32M26.31M49.82M70.64M41.91M41.29M-77.88M59.15M132.46M94.54M
Current Assets --------62.15M45.33M119.45M83.42M
Cash & Equivalents 7.01M3.61M2.09M3.39M51.10M6.90M12.46M-61.14M44.37M118.04M80.73M
Inventory -------5.82M0-0136.00K
Receivables -------61.00K0-0274.00K
Total Liabilities --1.02M3.83M4.31M11.18M18.40M-80.12M14.79M17.60M13.88M
Current Liabilities -660.00K1.02M2.21M3.11M4.46M7.58M-5.98M6.71M10.05M7.92M
Long Term Debt --------65.00M---
Total Debt --------75.96M9.14M8.90M7.53M
Total Equity 16.07M13.66M25.30M45.99M66.33M30.74M22.89M--2.25M44.36M114.86M80.66M
Shares Outstanding --------37.87M56.08M65.93M67.84M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -3.32M-8.05M-11.09M-23.90M-34.19M-35.37M-54.10M-47.01M-33.04M-36.34M-54.12M
Investing Cash Flow -86.00K-14.38M-23.00M26.12M-10.10M10.04M7.56M-401.00K-121.00K-125.00K-335.00K
Financing Cash Flow -20.91M35.38M45.50M82.00K30.89M62.69M79.94M16.39M110.14M17.15M
Capital Expenditure -86.00K-64.00K-2.55M-276.00K-608.00K-441.00K-437.00K-401.00K-121.00K-125.00K-315.00K
Free Cash Flow -3.40M-8.12M-13.64M-24.17M-34.79M-35.81M-54.53M-47.41M-33.16M-36.47M-54.44M

Ratios (Annual)

Figures in %.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % --------1,606.3%---54.0%
Operating Margin % --------8,293.9%---21,982.6%
Net Margin % --------8,357.9%---20,794.6%
ROE % -20.6%-37.6%-55.6%-56.6%-152.8%-217.7%-2,602.5%-95.2%-46.7%-90.2%
ROCE % -32.7%-37.6%-53.7%-55.6%-128.0%-148.2%--80.8%-83.1%-46.0%-88.8%

Shareholding Pattern

Insiders
71.04%
Institutions
15.38%
Public Float
53.13%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 2.12% 1.47M $69.77M
2 Bank of America Corporation 2.09% 1.45M $68.82M
3 Vanguard Capital Management LLC 1.14% 788.64K $37.52M
4 Portolan Capital Management, LLC 1.09% 753.33K $35.84M
5 Price (T.Rowe) Associates Inc 1.08% 748.64K $35.61M
6 Balyasny Asset Management LP 1.04% 718.10K $34.16M
7 Citadel Advisors Llc 0.91% 626.51K $29.80M
8 State Street Corporation 0.77% 529.62K $25.19M
9 Geode Capital Management, LLC 0.77% 536.28K $25.51M
10 Massachusetts Financial Services Co. 0.67% 462.73K $22.01M

Analyst View

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Latest News

Recent headlines for PLSE

Google News Sun, 16 Aug 2026

Pulse Biosciences (PLSE) Stock Looks Pricey On Book Value Yet Strong On Returns - Yahoo Finance

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Google News ue, 01 Sep 2026

$PLSE stock is up 7% today. Here's what we see in our data. - quiverquant.com

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Google News Wed, 02 Sep 2026

COO pays nearly $50 a share for Pulse Biosciences (NASDAQ: PLSE) - Stock Titan

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Google News Sat, 05 Sep 2026

(PLSE) Movement as an Input in Quant Signal Sets - Stock Traders Daily

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Google News Fri, 04 Sep 2026

Pulse Biosciences (PLSE) Grants Equity Awards to New Hires Amid High Price-to-Sales Valuation - GuruFocus

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Google News hu, 03 Sep 2026

Pulse Biosciences COO Liane Teplitsky buys $99,971 in stock By Investing.com - Investing.com Nigeria

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PLSE — Frequently Asked Questions

What is the current share price of Pulse Biosciences, Inc. (PLSE)?

As of 2026-09-07 16:24 PDT, Pulse Biosciences, Inc. (PLSE) trades at $53.24 on NasdaqCM. Its 52-week range is $12.66 to $54.71.

What is the market capitalisation of PLSE?

Pulse Biosciences, Inc. (PLSE) has a market capitalisation of $3.80B on NasdaqCM.

What is the P/E ratio of PLSE?

PLSE trades at a trailing price-to-earnings (P/E) ratio of -48.40. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 43.63.

What is the return on equity (ROE) of PLSE?

PLSE has a return on equity (ROE) of -80.72%. Its return on capital employed (ROCE) is -88.83%.

Is PLSE a good stock to buy?

This page provides a data-driven analysis of Pulse Biosciences, Inc. (PLSE), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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