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Omeros Corporation OMER R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://www.omeros.com
Company Profile ↓
$18.95
+343.79% 1Y
Mkt Cap$1.37B
P/E16.62
P/B-15.06
52W High$19.32
52W Low$4.03
Book Value$-0.88
EPS (TTM)$1.14

Company Overview

Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases. The company's lead products candidate is the Narsoplimab (OMS721/MASP-2) for the treatment of hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); and in Phase II clinical trial to treat COVID-19 and acute respiratory distress syndrome. It also develops OMS1029 that has completed phase I clinical trials for mannan-binding lectin-associated serine protease 2 (MASP-2) and lectin pathway disorders; and OMS527 that is in phase I clinical trials for addictions and compulsive disorders, and movement disorders, as well as cocaine use disorder. In addition, the company's products under preclinical development comprise MASP-2, a pro-inflammatory protein target for the treatment of lectin pathway disorders; MASP-3 small-molecule inhibitors for alternative pathway disorders; OncotoX-AML, to treat acute myeloid leukemia; and Targeted Complement Activating Therapy, for Multidrug-resistant organisms. Omeros Corporation was incorporated in 1994 and is headquartered in Seattle, Washington.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 43.0% CAGR over the past five years.

Reasonable Valuation

Trades at a P/E of 16.6, below the sector median of 25.2.

Positive Free Cash Flow

Generates positive free cash flow, funding growth and shareholder returns internally.

Recent Developments

  • Trailing 12 Months Year-on-year growth — revenue -34.0%.
  • 5-Year Trend Long-term compounding — revenue CAGR 43.0%.

Growth & Price Performance

Compounded Sales Growth

5 Years:43.00%
1 Year:-33.98%

Stock Price Performance

1 Year:+343.79%
6 Months:+64.21%
3 Months:+93.56%
1 Month:+44.11%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 98% of range
$4.03 $19.32
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)70.14 · Overbought
Price Performance
1M+44.11%
3M+93.56%
6M+64.21%
1Y+343.79%
Valuation vs Sector

P/E of 16.62 is below the sector median of 25.17 — relatively cheaper than peers.

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 43.0% over 5 years.
  • Generates positive free cash flow.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
16.62
Industry PE
25.17
Forward P/E
49.87
PEG Ratio
0.81
Book Value
$-0.88
Price to Book
-15.06
P/S
96.66
EV/EBITDA
-10.09
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
43.00%
Profit 5Y
-
Revenue (YoY)
-33.98%
Earnings (YoY)
-

Profitability & Returns

ROCE
-49.60%
ROE
2.76%
ROA
-25.24%
Profit Margin
-
Op Margin
-
Gross Margin
-
EPS (Latest Qtr)
$0.62
EPS (TTM)
$1.14

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
2.48
Current Ratio
3.03
Debt
$226.61M
Total Assets
$286.17M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
4.08%
Chg in Prom Hold
0.53%
FII / Inst Holding
50.60%
Chg in FII Hold
0.12%

Financial Snapshot

Enterprise Value
$1.37B
Total Revenue (TTM)
$9.89M
EBITDA
$-104.33M
Free Cash Flow
$181.02M
Operating Cash Flow
$-94.76M
Shares Outstanding
72.38M
Gross Margin
-
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 OMER Omeros Corporation R2KR3KPHARMA 18.95 16.62 $1.37B 0.00% -49.60% 2.76% 43.00% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue ------------1.59M1.66M4.61M22.02M21.78M26.75M29.86M33.42M23.54M13.53M26.11M10.63M21.06M28.82M30.00M---------0--9.89M
Operating Income -17.93M-15.97M-19.30M-18.04M-19.45M-10.93M-12.04M-11.86M-12.72M-11.94M-5.11M-14.12M-27.69M-30.62M-35.44M-18.47M-19.24M-9.34M-11.10M-23.70M-23.68M-27.68M-25.43M-33.82M-45.29M-45.61M-39.83M-35.05M-37.44M-50.77M-35.71M-40.90M-48.15M-39.03M-59.16M-35.41M-34.97M-32.35M-26.39M-17.42M
Net Income -18.67M-16.68M-19.92M-19.83M-20.54M-12.61M-13.96M-19.63M-15.09M-14.36M-7.48M-16.55M-30.05M-33.70M-39.47M-23.53M-24.34M-14.45M-16.46M-29.23M-29.03M-33.29M-38.46M-37.27M-35.09M-28.59M-22.70M-33.01M-30.85M-17.46M-33.70M-37.29M-37.75M-37.18M-56.04M-32.23M-33.46M-25.42M-30.92M56.06M
Diluted EPS ----------------------0.61-0.66--0.57-0.46-0.36-0.53-0.49-0.28-0.54-0.59--0.63-0.97-0.56-0.58-0.43-0.470.62
R&D Expense 9.32M10.90M13.26M-15.43M10.23M12.49M-12.24M13.14M14.84M-18.14M19.41M26.86M-26.25M19.11M23.75M-28.91M24.13M31.32M-32.50M30.13M25.82M24.09M23.52M38.57M24.61M29.64M31.73M26.77M45.35M24.08M23.85M22.01M15.99M13.36M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 1.44M2.10M4.52M6.02M1.60M539.00K13.51M41.62M64.83M29.87M111.81M73.81M-----
Operating Income -20.76M-30.11M-27.41M-36.88M-50.52M-70.01M-71.24M-54.28M-43.90M-112.22M-146.04M-156.92M-173.62M-163.39M-164.53M-166.95M-122.80M
Net Income -21.09M-29.25M-28.55M-38.44M-39.80M-73.67M-75.10M-66.75M-53.48M-126.76M-84.49M-138.06M194.24M47.42M-117.81M-156.81M-3.35M
Diluted EPS -----------1.71-2.413.120.76-1.88-2.70-0.05
R&D Expense 16.93M23.46M23.72M31.92M36.30M47.95M48.38M50.70M55.60M89.86M106.32M107.61M118.78M112.72M114.87M119.52M81.30M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2008Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Oct 2016Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --45.70M26.98M26.57M16.54M10.83M48.99M-67.28M116.33M95.94M136.97M181.04M419.27M590.97M378.27M277.08M325.63M
Total Equity -91.17M43.15M20.47M-5.55M-6.53M-18.38M-42.65M-26.23M--37.45M-2.81M-100.16M-109.02M-120.75M23.78M85.68M-24.98M-182.61M-121.23M
Cash & Equivalents 12.73M820.00K3.28M4.00M1.52M1.38M354.00K1.36M-2.22M3.39M5.86M3.08M10.50M100.81M11.01M7.11M3.40M9.66M
Long Term Debt ---13.55M20.10M14.90M26.12M49.77M70.00M79.51M84.12M--236.29M313.46M315.29M213.16M164.90M87.90M
Current Liabilities --15.37M18.98M8.36M11.87M18.32M16.25M-16.07M26.31M37.36M55.46M36.74M51.79M136.38M53.32M79.53M78.06M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -19.03M-14.50M-25.67M-34.55M-29.70M-58.04M-65.21M-51.50M-36.23M-103.74M-60.07M-100.09M-109.72M-86.48M74.73M-148.80M-116.09M
Investing Cash Flow -52.40M19.92M16.91M-907.00K7.91M6.16M-20.61M-16.34M-37.60M25.15M-3.40M-67.03M193.71M-127.56M27.45M82.22M164.52M
Financing Cash Flow 59.52M-2.96M9.49M32.97M21.65M50.86M86.83M68.70M75.00M81.05M60.70M174.53M6.32M124.25M-106.08M62.88M-42.17M
Capital Expenditure -279.00K-807.00K-1.24M-642.00K-204.00K-28.00K-240.00K-126.00K-350.00K-567.00K-334.00K-283.00K-277.00K-113.00K-426.00K-165.00K-65.00K
Free Cash Flow -19.31M-15.31M-26.91M-35.19M-29.90M-58.07M-65.45M-51.63M-36.58M-104.30M-60.41M-100.37M-110.00M-86.60M74.30M-148.97M-116.16M
Share Buybacks ------------004.65M11.85M0

Ratios (Annual)

Figures in %.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----------------
Operating Margin % -1,437.5%-1,430.2%-605.9%-612.5%-3,157.2%-12,988.5%-527.3%-130.4%-67.7%-375.7%-130.6%-212.6%-----
Net Margin % -1,460.5%-1,389.6%-631.0%-638.4%-2,487.2%-13,668.5%-555.9%-160.4%-82.5%-424.4%-75.6%-187.0%-----
ROE % -48.9%-142.9%514.0%588.6%216.5%172.7%286.3%178.2%1,900.5%126.6%77.5%114.3%816.8%55.3%471.6%85.9%2.8%
ROCE % --99.3%-342.8%-202.5%-1,083.6%935.8%-217.6%-106.0%-48.8%-191.6%-179.2%-108.7%-47.2%-35.9%-50.6%-84.5%-49.6%

Shareholding Pattern

Insiders
4.08%
Institutions
50.60%
Public Float
52.76%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 8.35% 6.04M $112.49M
2 Ingalls & Snyder LLC 5.06% 3.66M $68.10M
3 UBS Group AG 4.35% 3.15M $58.59M
4 Vanguard Capital Management LLC 4.24% 3.07M $57.17M
5 State Street Corporation 3.20% 2.32M $43.17M
6 Geode Capital Management, LLC 2.64% 1.91M $35.63M
7 Stifel Financial Corporation 2.54% 1.84M $34.19M
8 Vanguard Portfolio Management LLC 1.33% 962.83K $17.92M
9 Corient Private Wealth LP 1.11% 801.41K $14.91M
10 Invesco Ltd. 1.04% 751.77K $13.99M

Analyst View

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Latest News

Recent headlines for OMER

Google News Mon, 07 Sep 2026

OMER Stock Surges 5% After Hours On Novo Nordisk Deal Windfall And Drug Launch Optimism - Stocktwits

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Google News Sat, 05 Sep 2026

OMER Stock Gains Ground As Commercial Rollout Of Yartemlea Exceeds Expectations - Stocktwits

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Google News ue, 01 Sep 2026

Omeros (OMER) Stock Looks Reasonable On Earnings But Stretched After A 431% Run - simplywall.st

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Google News Fri, 28 Aug 2026

What Makes Omeros (OMER) a Strong Momentum Stock: Buy Now? - Yahoo Finance

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OMER — Frequently Asked Questions

What is the current share price of Omeros Corporation (OMER)?

As of 2026-09-07 16:24 PDT, Omeros Corporation (OMER) trades at $18.95 on NasdaqGM. Its 52-week range is $4.03 to $19.32.

What is the market capitalisation of OMER?

Omeros Corporation (OMER) has a market capitalisation of $1.37B on NasdaqGM.

What is the P/E ratio of OMER?

OMER trades at a trailing price-to-earnings (P/E) ratio of 16.62. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is -15.06.

What is the return on equity (ROE) of OMER?

OMER has a return on equity (ROE) of 2.76%. Its return on capital employed (ROCE) is -49.60%.

Is OMER a good stock to buy?

This page provides a data-driven analysis of Omeros Corporation (OMER), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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