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Odyssey Therapeutics, Inc. ODTX PHARMA

Healthcare · Biotechnology · United States
https://odysseytx.com
Company Profile ↓
$26.97
+64.25% 1Y
Mkt Cap$1.30B
P/E-8.07
P/B2.77
52W High$28.76
52W Low$15.56
Book Value$8.79
EPS (TTM)$-3.34

Company Overview

Odyssey Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops medicines for autoimmune and inflammatory diseases. The company pipeline includes OD-001, an oral small molecule inhibitor of receptor-interacting protein kinase 2, which is in phase 2a trial for the treatment of ulcerative colitis; OD-002, an oral small molecule SLC15A4 inhibitor designed to block TLR7/8/9-mediated pathogenic inflammatory responses activation of interferon regulatory factor 5 (IRF5); OD-003, a protein therapeutic designed to agonize tumor necrosis factor receptor 2 selectively on Treg; a TSLP/IL-33 bispecific antagonist; an oral small molecule interleukin-1 receptor–associated kinase 4 scaffolding inhibitor; and a small molecule inhibitor of IRF5. The company was incorporated in 2021 and is headquartered in Boston, Massachusetts.

Why Investors Should Care

Strong Return on Equity

Generates a return on equity of 30.4%, reflecting efficient use of shareholder capital.

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.06.

Recent Developments

  • Dec 2025 Revenue of $2.98M (-33.5% YoY); net profit $-148.65M.
  • Trailing 12 Months Year-on-year growth — revenue -33.5%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-
1 Year:-33.45%

Stock Price Performance

1 Year:+64.25%
6 Months:-
3 Months:+57.54%
1 Month:+27.40%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot
52-Week Range 86% of range
$15.56 $28.76
Trend Signals
  • Price vs 50-DMAAbove
  • RSI (14)62.49 · Neutral
Price Performance
1M+27.40%
3M+57.54%
1Y+64.25%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Strong return on equity of 30.4%.

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-8.07
Industry PE
24.83
Forward P/E
-6.19
PEG Ratio
-
Book Value
$8.79
Price to Book
2.77
P/S
11,835.02
EV/EBITDA
-5.86
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-33.45%
Earnings (YoY)
-

Profitability & Returns

ROCE
-66.23%
ROE
30.44%
ROA
-55.10%
Profit Margin
0.00%
Op Margin
-
Gross Margin
0.00%
EPS (Latest Qtr)
$-1.74
EPS (TTM)
$-3.34

Balance Sheet & Liquidity

Debt/Equity
0.06
Quick Ratio
10.98
Current Ratio
11.36
Debt
$24.82M
Total Assets
$483.85M
Current Assets
$185.10M
Working Capital
$164.18M

Ownership

Promoter Holding
6.19%
Chg in Prom Hold
0.12%
FII / Inst Holding
82.91%
Chg in FII Hold
-

Financial Snapshot

Enterprise Value
$1.30B
Total Revenue (TTM)
$99.00K
EBITDA
$-150.27M
Free Cash Flow
$-130.70M
Operating Cash Flow
$-132.13M
Shares Outstanding
48.06M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 ODTX Odyssey Therapeutics, Inc. PHARMA 26.97 -8.07 $1.30B 0.00% -66.23% 30.44% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Dec 2024Mar 2025Jun 2025Mar 2026Jun 2026
Revenue 1.75M1.92M959.00K00
Cost of Revenue -----
Gross Profit -----
Operating Expenses 38.88M46.73M-39.67M-
Operating Income -37.12M-44.81M-41.92M-39.67M-55.47M
EBITDA -34.59M-36.99M--37.02M-
Interest Expense 4.00K2.00K-10.00K-
Pretax Income -35.88M-38.30M--38.20M-
Tax Provision 47.00K140.00K-63.00K-
Net Income -35.93M-38.44M-41.23M-38.26M-52.79M
Diluted EPS --1.39-29.54-0.81-1.74
R&D Expense -38.77M30.23M32.32M36.23M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 01.04M4.47M2.98M
Cost of Revenue ----
Gross Profit ----
Operating Expenses 122.78M134.48M139.69M164.13M
Operating Income -122.78M-133.44M-135.22M-161.16M
EBITDA -121.26M-120.25M-123.64M-144.65M
Interest Expense 291.00K335.00K18.00K17.00K
Pretax Income -124.32M-125.49M-128.85M-149.57M
Tax Provision 347.00K447.00K469.00K-927.00K
Net Income -124.67M-125.94M-129.32M-148.65M
Diluted EPS -4.52-1.32-4.73-5.39

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets 317.15M286.52M197.44M269.79M
Current Assets 248.71M192.54M135.51M190.66M
Cash & Equivalents 241.04M52.55M59.14M41.69M
Inventory ----
Receivables ----
Total Liabilities 461.77M549.23M579.96M758.07M
Current Liabilities 22.80M22.09M28.41M26.48M
Long Term Debt 4.76M---
Total Debt 42.49M34.38M31.01M27.11M
Total Equity -144.62M-262.71M-382.53M-488.28M
Shares Outstanding 47.17M47.17M47.17M47.17M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -99.84M-112.73M-117.47M-129.47M
Investing Cash Flow -13.03M-165.02M96.78M-103.94M
Financing Cash Flow 182.72M92.08M26.98M215.65M
Capital Expenditure -13.03M-5.06M-764.00K-1.23M
Free Cash Flow -112.87M-117.78M-118.23M-130.70M
Net Change in Cash 69.85M-185.67M6.29M-17.77M

Ratios (Annual)

Figures in %.

Metric Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ----
Operating Margin % --12,867.8%-3,023.8%-5,415.2%
Net Margin % --12,144.5%-2,891.8%-4,994.9%
ROE % 86.2%47.9%33.8%30.4%
ROCE % -41.7%-50.5%-80.0%-66.2%

Shareholding Pattern

Insiders
6.19%
Institutions
82.91%
Public Float
88.38%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 10.78% 5.18M $126.27M
2 SR One Capital Management, LP 7.90% 3.79M $92.52M
3 TPG GP A, LLC 7.68% 3.69M $89.97M
4 Lightspeed Management Company, L.L.C. 7.51% 3.61M $87.97M
5 Orbimed Advisors LLC. 6.24% 3.00M $73.17M
6 Sanofi 4.14% 1.99M $48.56M
7 Deerfield Management Company, L.P 2.18% 1.05M $25.50M
8 Sands Capital Alternatives, LLC 1.82% 875.00K $21.33M
9 HHLR Advisors, LTD 1.73% 831.66K $20.28M
10 General Catalyst Group Management, LLC 1.69% 810.27K $19.75M

Analyst View

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Latest News

Recent headlines for ODTX

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Google News Sun, 09 Aug 2026

Odyssey Therapeutics (ODTX) Stock Looks Reasonable As AI Research News Lands - simplywall.st

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Google News Mon, 10 Aug 2026

Odyssey Therapeutics (ODTX) Looks Fully Valued As Earnings And Evotec Deal Refocus Attention - finance.yahoo.com

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ODTX — Frequently Asked Questions

What is the current share price of Odyssey Therapeutics, Inc. (ODTX)?

As of 2026-09-19 21:16 PDT, Odyssey Therapeutics, Inc. (ODTX) trades at $26.97 on NasdaqCM. Its 52-week range is $15.56 to $28.76.

What is the market capitalisation of ODTX?

Odyssey Therapeutics, Inc. (ODTX) has a market capitalisation of $1.30B on NasdaqCM.

What is the P/E ratio of ODTX?

ODTX trades at a trailing price-to-earnings (P/E) ratio of -8.07. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 2.77.

What is the return on equity (ROE) of ODTX?

ODTX has a return on equity (ROE) of 30.44%. Its return on capital employed (ROCE) is -66.23%.

Is ODTX a good stock to buy?

This page provides a data-driven analysis of Odyssey Therapeutics, Inc. (ODTX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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