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Natera, Inc. NTRA R3KPHARMA

Healthcare · Diagnostics & Research · United States
https://www.natera.com
Company Profile ↓
$324.14
+105.54% 1Y
Mkt Cap$46.72B
P/E-238.34
P/B29.12
52W High$338.70
52W Low$157.70
Book Value$12.68
EPS (TTM)$-1.36

Company Overview

Natera, Inc., a diagnostics company, engages in the development and commercialization of molecular testing services worldwide. It offers Signatera, a personalized ctDNA blood test for MRD assessment, early recurrence monitoring, and evaluation of treatment response in patients previously diagnosed with cancer; Latitude, a blood-based MRD test for colorectal cancer; Altera, a tissue based comprehensive genomic profiling test; and Empower, a hereditary cancer screening test. The company also provides Panorama, a non-invasive prenatal test; Horizon, a carrier screening test; Fetal Focus, a single-gene NIPT, or sgNIPT, that screens for 21 single-gene inherited conditions; and Vistara, a single-gene NIPT, which screens for 25 single-gene conditions. In addition, it offers Anora, which tests and analyzes miscarriage tissue from women who have experienced one or more pregnancy losses; Empower, a hereditary cancer screening test; Prospera, a test to assess active rejection in patients who have undergone solid organ transplantation; Renasight, a kidney gene panel test; and Constellation software, a cloud-based distribution model. Further, the company provides NateraCore, a platform to support the patient and provider experience; phlebotomy services; and EMR integration services. The company serves independent laboratories, national and regional reference laboratories, medical centers and physician practices for its screening tests, research laboratories, and pharmaceutical companies through its direct sales force and laboratory distribution partners, as well as Constellation licensees under its cloud-based distribution model. It has a partnership agreement with BGI Genomics Co., Ltd. to develop, manufacture, and commercialize NGS-based genetic testing assays for clinical and commercial use. The company has a collaboration with Diakonos Oncology Corp. to assess molecular response in patients with refractory melanoma. The company was formerly known as Gene Security Network, LLC and changed its name to Natera, Inc. in January 2012. Natera, Inc. was founded in 2003 and is headquartered in Austin, Texas.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 40.4% CAGR over the past five years.

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.13.

Positive Free Cash Flow

Generates positive free cash flow, funding growth and shareholder returns internally.

Recent Developments

  • Dec 2025 Revenue of $2.31B (+35.9% YoY); net profit $-208.16M.
  • Trailing 12 Months Year-on-year growth — revenue +37.7%.
  • 5-Year Trend Long-term compounding — revenue CAGR 40.4%.

Growth & Price Performance

Compounded Sales Growth

5 Years:40.40%
1 Year:37.70%

Stock Price Performance

1 Year:+105.54%
6 Months:+57.95%
3 Months:+51.84%
1 Month:+0.63%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 92% of range
$157.70 $338.70
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)58.52 · Neutral
Price Performance
1M+0.63%
3M+51.84%
6M+57.95%
1Y+105.54%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 40.4% over 5 years.
  • Generates positive free cash flow.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-238.34
Industry PE
24.83
Forward P/E
-
PEG Ratio
-
Book Value
$12.68
Price to Book
29.12
P/S
19.67
EV/EBITDA
-231.48
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
40.40%
Profit 5Y
-
Revenue (YoY)
37.70%
Earnings (YoY)
-

Profitability & Returns

ROCE
-15.84%
ROE
-12.54%
ROA
-8.08%
Profit Margin
-7.11%
Op Margin
-10.29%
Gross Margin
65.23%
EPS (Latest Qtr)
$-0.47
EPS (TTM)
$-1.36

Balance Sheet & Liquidity

Debt/Equity
0.13
Quick Ratio
2.74
Current Ratio
3.00
Debt
$238.49M
Total Assets
$2.66B
Current Assets
$1.65B
Working Capital
$1.06B

Ownership

Promoter Holding
2.82%
Chg in Prom Hold
-0.04%
FII / Inst Holding
96.74%
Chg in FII Hold
0.16%

Financial Snapshot

Enterprise Value
$46.72B
Total Revenue (TTM)
$2.71B
EBITDA
$-224.42M
Free Cash Flow
$104.03M
Operating Cash Flow
$228.24M
Shares Outstanding
144.14M
Gross Margin
65.23%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 NTRA Natera, Inc. R3KPHARMA 324.14 -238.34 $46.72B 0.00% -15.84% -12.54% 40.40% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue -------49.38M52.28M55.91M52.05M62.34M63.07M65.28M66.97M66.82M74.36M77.91M83.24M94.01M86.47M98.14M152.32M142.03M158.12M194.13M198.20M210.64M241.76M261.40M268.31M367.74M413.35M439.76M501.83M546.60M592.18M665.50M696.64M752.75M
Cost of Revenue ----------------------------------185.06M200.00M207.80M220.07M245.81M-
Gross Profit 19.36M14.46M21.10M29.56M21.01M19.63M11.30M15.68M17.72M21.30M15.32M21.75M22.07M23.60M24.18M23.52M30.53M34.03M38.78M---------------316.76M346.60M384.38M445.43M450.83M-
Operating Expenses ----------------------------------395.94M456.98M481.96M468.21M544.35M-
Operating Income -15.47M-20.74M--9.61M-22.52M-26.66M--34.55M-28.37M-25.79M--30.52M-27.22M-27.17M--31.75M-28.64M-21.09M--34.87M-51.66M-55.78M-63.02M-115.29M-150.20M-137.13M-143.09M-119.05M-138.30M-112.43M-110.98M-74.31M-43.90M-39.34M-79.18M-110.37M-97.58M-22.79M-93.52M-75.79M
EBITDA -----------------------------------56.52M-89.78M-76.00M1.76M-63.69M-
Interest Expense ----------------------------------1.00M1.03M1.04M991.00K892.00K-
Pretax Income -----------------------------------66.76M-100.66M-87.34M-13.33M-84.81M-
Tax Provision ----------------------------------173.00K275.00K207.00K-60.58M283.00K-
Net Income -19.68M-17.63M-22.96M-8.69M-23.16M-26.02M-37.91M-33.48M-29.07M-27.86M-47.22M-32.87M-33.82M-29.62M-31.84M-34.09M-32.42M-23.14M-35.18M-35.37M-59.64M-58.32M-63.85M-116.03M-151.27M-138.59M-145.15M-121.48M-136.94M-110.80M-109.03M-67.60M-37.46M-31.59M-66.94M-100.94M-87.54M47.26M-85.09M-66.97M
Diluted EPS --0.39--0.17-0.46-0.50-0.72-0.65-0.55-0.52-0.90-0.61-0.62-0.49-0.51-0.54-0.48-0.33-0.46----0.74-1.32-1.63-1.45-1.50-1.25-1.23-0.97-0.95-0.56-0.30-0.26-0.50-0.74-0.64--0.60-0.47
R&D Expense 6.74M7.34M-8.76M10.30M11.35M-12.65M11.79M12.61M-14.34M11.85M12.39M-11.44M12.12M12.80M-18.23M23.00M26.42M40.19M53.75M98.46M80.41M82.58M65.51M82.31M78.17M77.23M88.64M89.11M96.93M129.08M146.43M173.41M-210.70M228.07M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 55.17M159.29M190.35M212.51M209.62M257.65M302.33M391.00M-820.22M1.08B1.70B2.31B
Cost of Revenue ---------456.26M589.83M673.75M812.93M
Gross Profit ---------363.97M492.74M1.02B1.49B
Operating Expenses ---------905.01M938.99M1.25B1.80B
Operating Income -25.27M665.00K-59.84M-101.05M-135.34M-114.63M-116.29M-216.28M--541.04M-446.25M-222.29M-309.91M
EBITDA ----------520.80M-397.80M-148.08M-220.54M
Interest Expense ---------9.32M12.64M10.69M4.07M
Pretax Income ----------546.82M-434.53M-189.73M-268.09M
Tax Provision ---------978.00K271.00K695.00K-59.93M
Net Income -37.11M-5.15M-70.28M-100.33M-137.63M-128.15M-124.83M-229.74M--547.80M-434.80M-190.43M-208.16M
Diluted EPS ---2.68-1.95-2.59-2.22-1.79-2.84--5.57-3.78-1.53-1.52
R&D Expense 11.55M17.29M27.71M41.86M50.06M51.35M51.36M100.03M264.21M316.42M320.68M404.14M624.11M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --123.62M265.24M210.68M214.61M268.17M582.66M932.15M-1.39B1.44B1.66B2.40B
Current Assets ----------1.21B1.26B1.38B1.50B
Cash & Equivalents 5.75M30.50M87.18M28.95M15.26M12.62M46.41M61.93M48.67M-466.09M642.10M945.59M1.08B
Inventory ----------35.41M40.76M44.74M68.44M
Receivables ----------244.38M278.29M314.17M296.53M
Total Liabilities --54.35M80.47M104.20M189.20M236.01M303.94M445.92M-688.73M676.37M465.31M685.93M
Current Liabilities --29.87M80.47M96.42M105.56M113.98M179.87M199.05M-310.50M307.27M344.05M441.23M
Long Term Debt ---------280.39M281.65M282.94M--
Total Debt ----------446.22M441.99M187.12M214.38M
Total Equity -136.31M-171.51M-171.34M226.43M143.58M25.42M32.16M278.71M486.24M-705.74M765.33M1.20B1.71B
Shares Outstanding ----------111.25M119.58M132.65M139.69M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow ---37.83M-74.05M-97.83M-70.58M-63.44M-182.51M--431.50M-246.96M135.66M215.30M
Investing Cash Flow ---210.68M47.03M13.78M-5.16M-266.35M-331.46M-330.34M168.50M137.62M-132.21M
Financing Cash Flow --190.28M13.18M80.37M113.72M340.77M500.85M-482.64M254.46M30.20M47.46M
Capital Expenditure -8.24M-9.96M-7.85M-23.14M-9.87M-3.88M-4.97M-19.60M--47.70M-39.20M-76.92M-139.19M
Free Cash Flow ---45.68M-97.19M-107.69M-74.46M-68.41M-202.12M--479.20M-286.15M58.75M76.11M
Net Change in Cash ---------381.48M176.00M303.49M130.55M

Ratios (Annual)

Figures in %.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------44.4%45.5%60.3%64.7%
Operating Margin % -45.8%0.4%-31.4%-47.6%-64.6%-44.5%-38.5%-55.3%--66.0%-41.2%-13.1%-13.4%
Net Margin % -67.3%-3.2%-36.9%-47.2%-65.7%-49.7%-41.3%-58.8%--66.8%-40.2%-11.2%-9.0%
ROE % 21.6%3.0%-31.0%-69.9%-541.5%-398.5%-44.8%-47.2%--77.6%-56.8%-15.9%-12.2%
ROCE % -0.7%-32.4%-88.4%-124.1%-74.3%-28.9%-29.5%--49.9%-39.3%-16.9%-15.8%

Shareholding Pattern

Insiders
2.82%
Institutions
96.74%
Public Float
99.54%

Top Institutional Holders

#Holder% HeldSharesValue
1 JPMORGAN CHASE & CO 8.93% 12.87M $4.75B
2 Blackrock Inc. 7.57% 10.91M $4.03B
3 Price (T.Rowe) Associates Inc 6.26% 9.02M $3.33B
4 Vanguard Capital Management LLC 4.32% 6.23M $2.30B
5 Vanguard Portfolio Management LLC 4.01% 5.78M $2.14B
6 FMR, LLC 3.78% 5.45M $2.01B
7 Wellington Management Group, LLP 2.80% 4.04M $1.49B
8 State Street Corporation 2.54% 3.66M $1.35B
9 Duquesne Family Office Llc 2.21% 3.19M $1.18B
10 Geode Capital Management, LLC 1.91% 2.75M $1.02B

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for NTRA

Yahoo Finance ue, 01 Sep 2026

New Publication Establishes Strong Clinical Validation of Signatera™ for MRD Assessment in Lymphoma

AUSTIN, Texas, September 01, 2026--Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA and precision medicine, today announced the publication of new data in Blood Neoplasia, validating the prognostic and predictive value of Signa…

Yahoo Finance Sat, 29 Aug 2026

Billionaire Stanley Druckenmiller Has Roughly 17% of His $5.2 Billion Duquesne Portfolio in Natera Stock. Is It Still a Buy After an 80% Run?

The billionaire has good reasons to like this genetic testing leader.

Yahoo Finance Fri, 28 Aug 2026

Natera & Angiex Partner to Evaluate AGX101 Response With Signatera

NTRA teams with Angiex to use Signatera in a Phase 1 AGX101 trial, aiming to track ctDNA and deepen insights into treatment response.

Yahoo Finance Fri, 28 Aug 2026

Natera and Susan G. Komen® Announce National Partnership to Accelerate Progress Against Breast Cancer

AUSTIN, Texas, August 28, 2026--Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing and precision medicine, today announced a national partnership with Susan G. Komen®, the world’s leading breast cancer organization. Toget…

Yahoo Finance hu, 27 Aug 2026

3 Healthcare Stocks with Promising Prospects

Personal health and wellness is one of the many secular tailwinds for healthcare companies. Players catalyzing medical advancements have benefited from elevated demand, and their momentum is only rising as the industry has posted a 24.9% ga…

Yahoo Finance hu, 27 Aug 2026

Natera and Angiex Partner to Assess Response to Investigational Nuclear-Delivered Antibody-Drug Conjugate™ Using Signatera™

AUSTIN, Texas, August 27, 2026--Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA and precision medicine, today announced a new Signatera collaboration with Angiex, Inc., a privately held biotech company developing a portfolio o…

NTRA — Frequently Asked Questions

What is the current share price of Natera, Inc. (NTRA)?

As of 2026-09-19 21:16 PDT, Natera, Inc. (NTRA) trades at $324.14 on NasdaqGS. Its 52-week range is $157.70 to $338.70.

What is the market capitalisation of NTRA?

Natera, Inc. (NTRA) has a market capitalisation of $46.72B on NasdaqGS.

What is the P/E ratio of NTRA?

NTRA trades at a trailing price-to-earnings (P/E) ratio of -238.34. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 29.12.

What is the return on equity (ROE) of NTRA?

NTRA has a return on equity (ROE) of -12.54%. Its return on capital employed (ROCE) is -15.84%.

Is NTRA a good stock to buy?

This page provides a data-driven analysis of Natera, Inc. (NTRA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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