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$24.28
+15.02% 1Y
Mkt Cap$485.88M
P/E-4.82
P/B2.34
52W High$42.84
52W Low$16.37
Book Value$13.72
EPS (TTM)$-5.04

Company Overview

Neurogene Inc., a clinical stage biotechnology company, develops genetic medicines for rare neurological diseases. The company's product candidates include NGN-401 that is packaged in an adeno-associated virus 9, which is in Phase 1/2 clinical trial for the treatment of Rett syndrome; and NGN-101, a conventional gene therapy candidate that is in Phase 1/2 clinical trial to treat CLN5 Batten disease. It has a license agreement with The University of Edinburgh, Virovek, Inc., Sigma-Aldrich Co. LLC., and Leland Stanford Junior University. The company was founded in 2018 and is headquartered in New York, New York.

Recent Developments

  • Trailing 12 Months Year-on-year growth — revenue -100.0%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-
1 Year:-100.00%

Stock Price Performance

1 Year:+15.02%
6 Months:-9.91%
3 Months:-30.43%
1 Month:-21.50%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 30% of range
$16.37 $42.84
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)39.50 · Neutral
Price Performance
1M-21.50%
3M-30.43%
6M-9.91%
1Y+15.02%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Trading 43.3% below its 52-week high.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-4.82
Industry PE
25.61
Forward P/E
-4.69
PEG Ratio
-
Book Value
$13.72
Price to Book
2.34
P/S
-
EV/EBITDA
-3.60
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-100.00%
Earnings (YoY)
-

Profitability & Returns

ROCE
-37.96%
ROE
-45.31%
ROA
-27.98%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-1.39
EPS (TTM)
$-5.04

Balance Sheet & Liquidity

Debt/Equity
3.84
Quick Ratio
10.50
Current Ratio
10.64
Debt
$8.35M
Total Assets
$263.14M
Current Assets
$246.75M
Working Capital
$227.88M

Ownership

Promoter Holding
6.98%
Chg in Prom Hold
0.00%
FII / Inst Holding
97.59%
Chg in FII Hold
8.65%

Financial Snapshot

Enterprise Value
$485.88M
Total Revenue (TTM)
$0
EBITDA
$-117.99M
Free Cash Flow
$-48.08M
Operating Cash Flow
$-86.82M
Shares Outstanding
20.01M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 NGNE Neurogene Inc. R2KR3KPHARMA 24.28 -4.82 $485.88M 0.00% -37.96% -45.31% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,306.69 43.95 $1.16T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 267.61 31.05 $644.91B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 285.19 80.56 $503.96B 2.54% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 424.98 27.29 $381.46B 2.47% 9.74% 14.15% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPXR3KPHARMA 147.24 117.79 $363.27B 2.31% - 6.96% 5.64% 10.01%
7 NVS Novartis AG PHARMA 156.27 23.61 $297.02B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 172.57 25.80 $267.64B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 676.54 36.45 $250.15B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2013Jun 2013Sep 2013Mar 2014Jun 2014Sep 2014Mar 2015Jun 2015Sep 2015Mar 2016Jun 2016Sep 2016Mar 2017Jun 2017Sep 2017Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue ----------------25.00M--------------00-925.00K0-00-
Operating Income --------------13.99M-12.07M-2.69M-15.20M--428.00K-59.52M-9.07M-9.77M-2.25M-14.95M-15.12M-15.45M-15.37M-15.87M-13.61M-13.04M-12.60M-15.22M-18.78M-20.13M-22.18M-25.92M-26.08M-23.80M-33.35M
Net Income -1.01M-811.50K-3.37M-4.23M-5.42M-6.28M-6.41M-4.75M-5.04M-6.71M-10.90M-8.15M-8.32M-13.77M-11.83M-14.62M2.92M-14.99M-2.21M-1.00K-59.13M-8.64M-9.75M-2.25M-14.95M-15.13M-15.45M-15.35M-15.69M-13.07M-12.26M-11.86M-14.58M-16.92M-18.49M-20.22M-22.65M-22.02M-20.95M-30.93M
Diluted EPS -8.48---1.28----------0.59--0.12-----0.18-0.20-0.04-0.27-0.27-0.28-0.28-0.28-1.18-0.26-26.68-32.67-1.00-1.09-1.19-1.08-1.05-0.99-1.39
R&D Expense 572.97K1.25M3.03M1.88M4.55M5.32M4.57M3.62M3.69M4.88M9.23M6.13M5.78M10.47M8.46M10.51M18.00M10.71M104.00K--5.50M4.84M6.22M9.71M9.82M9.90M10.70M10.96M9.47M10.28M10.32M11.61M13.54M15.74M16.29M17.76M19.37M17.24M25.15M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue ------25.00M----0925.00K0
Operating Income -----37.65M-51.12M-32.62M-70.96M-33.73M-60.70M-56.52M-55.58M-82.61M-103.33M
Net Income -7.71M-8.73M-24.03M-21.86M-37.00M-50.18M-31.59M-69.44M-33.28M-60.69M-55.19M-36.32M-75.14M-90.35M
Diluted EPS ---------0.64-1.10-1.04--4.28-4.24
R&D Expense 6.05M7.60M18.08M15.80M28.38M36.27M41.79M--39.16M47.51M44.39M60.92M75.01M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Mar 2014Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --15.65M-41.42M113.34M154.38M110.33M77.62M147.02M210.52M163.26M109.27M222.57M335.73M288.60M
Total Equity -39.31M-51.10M-65.69M-65.39M36.15M108.42M144.66M98.89M72.67M141.69M191.22M-91.88M-145.74M186.02M310.38M264.89M
Cash & Equivalents 9.24M2.00M11.01M-14.91M39.53M32.30M52.03M76.93M143.09M192.56M142.47M82.02M148.21M136.59M103.84M
Total Liabilities --7.48M-5.28M4.92M9.72M11.44M4.95M5.34M19.30M20.40M10.64M36.55M25.36M23.72M
Current Liabilities --2.62M-5.20M4.79M9.52M10.96M4.63M4.74M7.89M8.64M6.65M22.97M15.16M16.41M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -----30.23M-44.72M-31.58M-15.39M-24.57M-47.56M-52.82M-51.42M-70.60M-77.17M
Investing Cash Flow -----48.06M64.01M55.95M-688.00K-2.22M-3.26M-2.23M25.64M-125.26M14.00M
Financing Cash Flow ----71.11M423.00K570.00K82.24M77.14M732.00K66.53M92.48M184.07M30.43M
Capital Expenditure -6.45K-11.00K-114.00K-26.00K-713.00K-494.00K-49.00K-879.00K-2.22M-3.26M-2.23M-321.00K-808.00K-1.18M
Free Cash Flow -----30.94M-45.21M-31.63M-16.27M-26.79M-50.82M-55.05M-51.74M-71.41M-78.36M

Ratios (Annual)

Figures in %.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % --------------
Operating Margin % -------130.5%------8,930.3%-
Net Margin % -------126.3%------8,123.7%-
ROE % 15.1%13.3%-66.5%-20.2%-25.6%-50.7%-43.5%-49.0%-17.4%66.1%37.9%-19.5%-24.2%-34.1%
ROCE % -----26.0%-51.4%-44.7%-49.9%-16.6%-39.3%-55.1%-27.8%-25.8%-38.0%

Shareholding Pattern

Insiders
6.98%
Institutions
97.59%
Public Float
104.91%

Top Institutional Holders

#Holder% HeldSharesValue
1 Samsara BioCapital, LLC 8.58% 1.72M $45.33M
2 Casdin Capital, LLC 7.72% 1.55M $40.80M
3 Redmile Group, LLC 7.06% 1.41M $37.28M
4 RTW Investments LP 6.81% 1.36M $35.97M
5 EcoR1 Capital, LLC 6.35% 1.27M $33.56M
6 Blackrock Inc. 5.29% 1.06M $27.93M
7 Baker Bros. Advisors, LP 4.96% 991.69K $26.18M
8 Balyasny Asset Management LP 4.09% 818.71K $21.61M
9 Trails Edge Capital Partners, LP 3.57% 714.88K $18.87M
10 Toronto Dominion Bank 3.40% 681.34K $17.99M

Analyst View

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Latest News

Recent headlines for NGNE

Google News ue, 20 Oct 2026

New Rett syndrome data will examine how quickly a gene therapy’s instructions become active. - Stock Titan

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Google News hu, 25 Jun 2026

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$NGNE stock is down 10% today. Here's what we see in our data. - Quiver Quantitative

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Google News Fri, 25 Sep 2026

Neurogene Inc. (NGNE) Stock Price & News - Syfe

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NGNE — Frequently Asked Questions

What is the current share price of Neurogene Inc. (NGNE)?

As of 2026-10-22 16:30 PDT, Neurogene Inc. (NGNE) trades at $24.28 on NasdaqGM. Its 52-week range is $16.37 to $42.84.

What is the market capitalisation of NGNE?

Neurogene Inc. (NGNE) has a market capitalisation of $485.88M on NasdaqGM.

What is the P/E ratio of NGNE?

NGNE trades at a trailing price-to-earnings (P/E) ratio of -4.82. The industry average P/E is 25.61. Its price-to-book (P/B) ratio is 2.34.

What is the return on equity (ROE) of NGNE?

NGNE has a return on equity (ROE) of -45.31%. Its return on capital employed (ROCE) is -37.96%.

Is NGNE a good stock to buy?

This page provides a data-driven analysis of Neurogene Inc. (NGNE), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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