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Mineralys Therapeutics, Inc. MLYS R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://mineralystx.com
Company Profile ↓
$20.55
+51.55% 1Y
Mkt Cap$1.81B
P/E-4.89
P/B4.49
52W High$47.33
52W Low$13.56
Book Value$6.24
EPS (TTM)$-4.20

Company Overview

Mineralys Therapeutics, Inc., a biopharmaceutical company, develops medicines to target diseases driven by dysregulated aldosterone in the United States. It is developing lorundrostat, a proprietary, orally administered, highly selective aldosterone synthase inhibitor for the treatment of cardiorenal conditions affected by dysregulated aldosterone, such as hypertension, chronic kidney disease, and obstructive sleep apnea. The company was formerly known as Catalys SC1, Inc. and changed its name to Mineralys Therapeutics, Inc. in May 2020. Mineralys Therapeutics, Inc. was incorporated in 2019 and is headquartered in Radnor, Pennsylvania.

Why Investors Should Care

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.18.

Growth & Price Performance

Stock Price Performance

1 Year:+51.55%
6 Months:-25.30%
3 Months:-24.48%
1 Month:-22.72%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 21% of range
$13.56 $47.33
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)36.53 · Neutral
Price Performance
1M-22.72%
3M-24.48%
6M-25.30%
1Y+51.55%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 56.6% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-4.89
Industry PE
25.45
Forward P/E
-8.22
PEG Ratio
-
Book Value
$6.24
Price to Book
4.49
P/S
-
EV/EBITDA
-5.15
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-26.38%
ROE
-80.88%
ROA
-46.18%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.47
EPS (TTM)
$-4.20

Balance Sheet & Liquidity

Debt/Equity
0.18
Quick Ratio
34.24
Current Ratio
34.46
Debt
$97.62M
Total Assets
$652.86M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
0.70%
Chg in Prom Hold
-0.08%
FII / Inst Holding
117.59%
Chg in FII Hold
-0.28%

Financial Snapshot

Enterprise Value
$1.81B
Total Revenue (TTM)
$0
EBITDA
$-370.75M
Free Cash Flow
$-203.46M
Operating Cash Flow
$-138.79M
Shares Outstanding
88.16M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 MLYS Mineralys Therapeutics, Inc. R2KR3KPHARMA 20.55 -4.89 $1.81B 0.00% -26.38% -80.88% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,273.46 42.83 $1.14T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 263.81 30.60 $635.76B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 285.64 80.69 $504.76B 2.54% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 418.09 26.85 $375.28B 2.47% 9.74% 14.15% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPXR3KPHARMA 145.27 116.22 $358.41B 2.31% - 6.96% 5.64% 10.01%
7 NVS Novartis AG PHARMA 151.12 22.83 $287.24B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 171.49 25.63 $265.96B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 673.82 36.30 $249.14B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Operating Income -7.57M-6.48M-7.42M-14.94M-15.73M-26.27M-35.36M-45.17M-60.11M-44.45M-46.75M-41.13M-45.34M
Net Income -7.57M-6.48M-6.68M-12.61M-12.14M-22.76M-31.51M-41.01M-56.34M-42.21M-43.27M-36.93M-39.34M
Diluted EPS -1.48-1.26-1.29-0.51-0.31-0.57-0.70-0.83-1.13-0.79-0.66-0.52-0.47
R&D Expense 6.78M5.59M6.06M12.29M11.88M22.50M30.75M39.27M53.98M37.88M38.28M31.45M24.36M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -0000
Cost of Revenue -----
Gross Profit -----
Operating Expenses -31.48M84.66M192.40M170.60M
Operating Income --31.48M-84.66M-192.40M-170.60M
EBITDA --31.48M-84.66M-192.36M-170.54M
Interest Expense 27.00K----
Pretax Income --29.80M-71.90M-177.81M-154.65M
Tax Provision -----
Net Income --29.80M-71.90M-177.81M-154.65M
Diluted EPS --0.76-1.99-3.66-2.29
R&D Expense -26.25M70.36M168.58M132.01M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -114.44M251.64M205.90M661.81M
Total Equity -22.93M-52.27M241.15M191.26M646.69M
Cash & Equivalents -87.70M49.30M114.09M172.92M
Current Liabilities -8.07M10.48M14.65M15.11M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -29.22M-81.17M-166.31M-142.42M
Investing Cash Flow -21.76M-160.47M114.96M-389.75M
Financing Cash Flow 128.02M203.25M116.14M591.00M

Ratios (Annual)

Figures in %.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----
Operating Margin % -----
Net Margin % -----
ROE % -57.0%-29.8%-93.0%-23.9%
ROCE % --29.6%-35.1%-100.6%-26.4%

Shareholding Pattern

Insiders
0.70%
Institutions
117.59%
Public Float
118.42%

Top Institutional Holders

#Holder% HeldSharesValue
1 Catalys Pacific, LLC 8.94% 7.90M $184.71M
2 RA Capital Management, L.P. 8.70% 7.69M $179.78M
3 Blackrock Inc. 6.66% 5.89M $137.58M
4 Samsara BioCapital, LLC 6.64% 5.87M $137.21M
5 FMR, LLC 5.10% 4.51M $105.44M
6 State Street Corporation 4.68% 4.14M $96.79M
7 Deerfield Management Company, L.P 4.48% 3.96M $92.50M
8 Vanguard Capital Management LLC 3.12% 2.76M $64.43M
9 Laurion Capital Management, LP 2.83% 2.51M $58.57M
10 Price (T.Rowe) Associates Inc 2.56% 2.26M $52.87M

Analyst View

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Latest News

Recent headlines for MLYS

Google News Fri, 03 Jul 2026

A $500 Million Funding Deal Could Make Mineralys Therapeutics (MLYS) Stock A Multibagger - Yahoo Finance

<a href="https://news.google.com/rss/articles/CBMilgFBVV95cUxPSDZPT0h6QTJfZnRCR0RBRTBWUE93elUzUlZGVmdqUXZkb19oRnpqWEUwckVvUXFWNWw0V0FxWlNadTkxQkpUZEY3NFFKQmlodkZlbDZPRWtfQ2czZklHWDF1QkJ1M0JFYThwVUMyZHlYT1JCTldUNmtMc0FqLUo2aTdzem5aSm5HRGRqMU…

Google News Fri, 23 Oct 2026

Why (MLYS) Price Action Is Critical for Tactical Trading - Stock Traders Daily

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Google News ue, 13 Oct 2026

Mineralys Therapeutics CEO Jon Congleton sells $1.9m MLYS stock - Investing.com

<a href="https://news.google.com/rss/articles/CBMixAFBVV95cUxPTDBsVjdpLWRIZjAxaUs5ZUFHaGZCU3dlQTJKX29EQWFtdXJMdHY1c1Rad2JlVmRwWEhlcDZ5aklzOVl2RDVmV05OVHRZN0piclUxc3RoZzZFNGFrc2hGaW9ycVg2eVp5WElId3hDN2lKdWJRVUhncm9EMDI0TzNxTDd4M1E5VDNhVktVUT…

Google News hu, 22 Oct 2026

A blood pressure drug cut urine protein 52% vs. placebo among people with kidney disease and protein in their urine. - Stock Titan

<a href="https://news.google.com/rss/articles/CBMisAFBVV95cUxQSm5aSlBzN0RVVTlaUjVXYjctV2RiQlJMNjlGRDc1YWlLU2Iyb0dRVmdjbEx3Nll6dnlVNHhCY1JvdGdOQVFtalpkMEhJN0N6U19iZFdvc0lpUFFaN3o0cTd0SGl4X2JmdlBqeWthUmh5d3pPVUdyY2d1Y3lSMFF2bC1LeEhkVE1PdC15dT…

Google News Sun, 18 Oct 2026

Mineralys Therapeutics (MLYS) Stock Dropped, So What Is Driving Attention Now? - Simply Wall Street

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Google News Fri, 26 Jun 2026

MLYS Forecast — Price Target — Prediction for 2027 - TradingView

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MLYS — Frequently Asked Questions

What is the current share price of Mineralys Therapeutics, Inc. (MLYS)?

As of 2026-10-23 16:27 PDT, Mineralys Therapeutics, Inc. (MLYS) trades at $20.55 on NasdaqGS. Its 52-week range is $13.56 to $47.33.

What is the market capitalisation of MLYS?

Mineralys Therapeutics, Inc. (MLYS) has a market capitalisation of $1.81B on NasdaqGS.

What is the P/E ratio of MLYS?

MLYS trades at a trailing price-to-earnings (P/E) ratio of -4.89. The industry average P/E is 25.45. Its price-to-book (P/B) ratio is 4.49.

What is the return on equity (ROE) of MLYS?

MLYS has a return on equity (ROE) of -80.88%. Its return on capital employed (ROCE) is -26.38%.

Is MLYS a good stock to buy?

This page provides a data-driven analysis of Mineralys Therapeutics, Inc. (MLYS), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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