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$4.32
+160.24% 1Y
Mkt Cap$275.18M
P/E-2.72
P/B6.14
52W High$4.86
52W Low$1.33
Book Value$0.67
EPS (TTM)$-1.59

Company Overview

MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics for the treatment of cancer in the United States. The company's product pipeline includes lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4 for the treatment of mCRPC and docetaxel that is in phase 2 clinical trials, as well as for the treatment of platinum-resistant ovarian cancer and clear cell gynecologic cancer which has completed phase 1 clinical trial; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload; MGC028, an antibody-drug conjugates (ADC) that targets ADAM9 and delivers a novel TOP1i-based linker-payload for the treatment of solid tumors, which is in phase 1 clinical trials; MGC030, a ADC molecule that targets an undisclosed antigen expressed across several solid tumors, which is in preclinical trials. It is also developing T-cell engager programs. The company has collaborations with TerSera Therapeutics LLC; Incyte Corporation; and Gilead Sciences, Inc. MacroGenics, Inc. was incorporated in 2000 and is headquartered in Rockville, Maryland.

Recent Developments

  • Dec 2025 Revenue of $149.50M (-0.3% YoY); net profit $-74.62M.
  • Trailing 12 Months Year-on-year growth — revenue +378.0%.
  • 5-Year Trend Long-term compounding — revenue CAGR 7.1%.

Growth & Price Performance

Compounded Sales Growth

5 Years:7.10%
1 Year:378.00%

Stock Price Performance

1 Year:+160.24%
6 Months:+83.05%
3 Months:+11.34%
1 Month:+6.93%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 85% of range
$1.33 $4.86
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)56.10 · Neutral
Price Performance
1M+6.93%
3M+11.34%
6M+83.05%
1Y+160.24%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-2.72
Industry PE
24.83
Forward P/E
-2.95
PEG Ratio
-
Book Value
$0.67
Price to Book
6.14
P/S
1.51
EV/EBITDA
-3.90
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
7.10%
Profit 5Y
-
Revenue (YoY)
378.00%
Earnings (YoY)
-

Profitability & Returns

ROCE
-34.08%
ROE
-
ROA
-8.05%
Profit Margin
-8.33%
Op Margin
-42.19%
Gross Margin
-0.74%
EPS (Latest Qtr)
$-0.58
EPS (TTM)
$-1.59

Balance Sheet & Liquidity

Debt/Equity
0.82
Quick Ratio
2.92
Current Ratio
2.96
Debt
$35.09M
Total Assets
$217.87M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
3.48%
Chg in Prom Hold
0.06%
FII / Inst Holding
77.62%
Chg in FII Hold
0.09%

Financial Snapshot

Enterprise Value
$275.18M
Total Revenue (TTM)
$175.14M
EBITDA
$-32.17M
Free Cash Flow
$-69.41M
Operating Cash Flow
$-63.72M
Shares Outstanding
63.70M
Gross Margin
-0.74%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 MGNX MacroGenics, Inc. PHARMA 4.32 -2.72 $275.18M 0.00% -34.08% - 7.10% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Dec 2014Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue 5.48M71.28M6.72M14.68M8.18M2.85M80.67M3.25M5.11M2.06M1.67M1.66M152.36M4.70M18.83M20.80M15.79M9.66M10.59M18.74M25.19M13.68M20.26M18.25M16.88M30.76M15.66M11.10M26.01M41.73M24.50M13.14M10.40M9.10M10.80M110.71M13.19M22.24M72.84M20.77M
Operating Income -45.13M-21.29M-15.44M--30.63M40.09M-34.27M--38.21M-41.18M-47.72M--50.21M-44.31M-35.00M--47.62M-52.97M-37.94M--45.45M-47.31M-36.13M-51.29M-40.28M-52.99M-66.64M-41.81M-24.95M-38.43M-44.96M-35.50M-53.75M-58.18M54.19M-42.62M-36.76M18.64M-33.44M
Net Income -19.02M45.13M-21.38M-15.44M-28.45M-30.36M40.46M-33.85M-34.78M-37.66M-40.65M-47.04M105.73M-49.54M-43.24M-34.03M-44.64M-45.02M-31.77M-44.63M-30.40M-44.72M-46.88M-36.04M-51.27M-39.94M-52.89M-66.44M-41.30M-24.81M-38.01M57.47M17.55M-52.19M-55.66M56.31M-41.04M-36.25M16.82M-36.77M
Diluted EPS -1.42-0.71-0.46-0.83-0.881.12-0.97-1.00-1.08-1.14-1.282.80----------0.94-0.66-0.90-0.66-0.86-1.08-0.67-0.40-0.610.920.28-0.84-0.890.90-0.65-0.570.27-0.58
R&D Expense -21.46M22.66M24.10M-27.35M33.34M30.30M-32.80M34.46M40.98M-45.67M52.01M46.22M-47.06M51.44M44.85M-48.89M57.35M44.66M53.12M55.78M49.82M61.44M51.74M48.19M45.87M43.23M30.13M46.03M51.73M40.54M39.70M40.79M32.71M34.97M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 57.21M63.83M58.03M47.80M100.85M91.88M157.74M60.12M64.19M104.88M77.45M151.94M58.75M149.96M149.50M
Operating Income 5.25M8.21M366.00K-38.31M-20.18M-60.04M-22.14M-171.21M-177.19M-131.06M-202.79M-121.42M-168.24M-110.58M-72.84M
Net Income 6.72M8.36M-261.00K-38.31M-20.14M-58.53M-19.63M-171.45M-151.81M-129.74M-202.12M-119.76M-9.06M-66.97M-74.62M
Diluted EPS 0.000.00-0.04-1.40------2.47-3.37-1.95-0.15-1.07-1.18
R&D Expense 41.09M45.43M46.58M70.19M98.27M122.09M147.23M190.83M195.31M193.20M214.58M207.03M166.58M177.19M147.17M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --53.75M125.78M173.89M359.27M311.26M373.88M332.13M312.50M378.74M335.25M280.47M298.42M261.65M256.85M
Total Equity -38.63M-17.48M-8.24M78.91M121.29M313.34M268.75M299.24M242.88M230.63M295.88M239.62M142.01M152.61M116.06M55.59M
Cash & Equivalents 36.88M55.22M47.74M116.48M157.59M196.17M84.10M211.73M220.13M126.47M181.13M123.47M108.88M100.96M182.84M57.22M
Total Liabilities --61.98M46.87M52.60M45.93M42.51M74.64M89.25M81.87M82.86M95.63M138.46M145.81M145.60M201.25M
Current Liabilities --29.73M28.82M27.09M24.20M27.30M49.76M59.94M45.17M50.67M74.58M48.61M56.11M55.53M43.12M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow 6.76M-6.58M-14.17M---14.40M-153.23M-134.27M-111.90M-143.83M-86.96M-78.20M-68.37M-81.04M
Investing Cash Flow -500.21K-940.04K-2.96M---77.88M56.64M-79.36M-7.79M-36.61M70.72M-80.08M149.30M-114.10M
Financing Cash Flow 12.09M46.83K85.87M---35.35M104.99M119.97M174.34M122.78M1.66M150.36M960.00K69.51M
Capital Expenditure -500.21K-940.00K-2.96M-3.57M-9.20M-11.38M-29.40M-24.95M-4.29M-5.91M-6.20M-3.62M-1.76M-3.71M-1.91M
Free Cash Flow 6.26M-7.52M-17.13M----15.00M-178.19M-138.56M-117.80M-150.03M-90.58M-79.97M-72.08M-82.95M

Ratios (Annual)

Figures in %.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------------
Operating Margin % 9.2%12.9%0.6%-80.2%-20.0%-65.3%-14.0%-284.8%-276.0%-125.0%-261.9%-79.9%-286.4%-73.7%-48.7%
Net Margin % 11.7%13.1%-0.4%-80.2%-20.0%-63.7%-12.4%-285.2%-236.5%-123.7%-261.0%-78.8%-15.4%-44.7%-49.9%
ROE % -38.4%-101.5%-0.3%-31.6%-6.4%-21.8%-6.6%-70.6%-65.8%-43.8%-84.3%-84.3%-5.9%-57.7%-134.2%
ROCE % -34.2%0.4%-26.1%-6.0%-21.1%-6.8%-62.9%-66.3%-39.9%-77.8%-52.4%-69.4%-53.6%-34.1%

Shareholding Pattern

Insiders
3.48%
Institutions
77.62%
Public Float
80.42%

Top Institutional Holders

#Holder% HeldSharesValue
1 Armistice Capital, LLC 7.86% 5.01M $20.73M
2 Blackrock Inc. 7.35% 4.68M $19.37M
3 Vanguard Capital Management LLC 4.17% 2.66M $11.00M
4 Renaissance Technologies, LLC 4.13% 2.63M $10.90M
5 Acadian Asset Management. LLC 3.99% 2.54M $10.53M
6 Bank of America Corporation 3.91% 2.49M $10.30M
7 Two Sigma Investments, LP 3.87% 2.47M $10.21M
8 Millennium Management Llc 3.73% 2.37M $9.83M
9 Wasatch Advisors LP 3.17% 2.02M $8.36M
10 RA Capital Management, L.P. 2.93% 1.86M $7.72M

Analyst View

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Latest News

Recent headlines for MGNX

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MGNX — Frequently Asked Questions

What is the current share price of MacroGenics, Inc. (MGNX)?

As of 2026-09-19 21:16 PDT, MacroGenics, Inc. (MGNX) trades at $4.32 on NasdaqGS. Its 52-week range is $1.33 to $4.86.

What is the market capitalisation of MGNX?

MacroGenics, Inc. (MGNX) has a market capitalisation of $275.18M on NasdaqGS.

What is the P/E ratio of MGNX?

MGNX trades at a trailing price-to-earnings (P/E) ratio of -2.72. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 6.14.

Is MGNX a good stock to buy?

This page provides a data-driven analysis of MacroGenics, Inc. (MGNX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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