Company Overview
Seres Therapeutics, Inc., a clinical-stage company, focuses on developing biotherapeutics for serious diseases. The company develops SER-155, an investigational oral live biotherapeutic to decolonize GI pathogens, enhance GI epithelial barrier integrity, and regulate immune response to prevent bacterial bloodstream infections, as well as other pathogen-associated negative clinical outcomes in patients undergoing allogeneic hematopoietic stem cell transplantation. It also develops SER-603, a LBP candidate optimized to treat disruptions in the GI microbiome and to improve GI mucosal barrier integrity through the inhibition of inflammatory bacteria and associated metabolites; and SER-147, a live biotherapeutic composition to prevent bacterial bloodstream and spontaneous bacterial peritonitis infections in patients with metabolic disease, including chronic liver disease. The company was formerly known as Seres Health, Inc. and changed its name to Seres Therapeutics, Inc. in May 2015. Seres Therapeutics, Inc. was incorporated in 2010 and is headquartered in Cambridge, Massachusetts.
Recent Developments
- Trailing 12 Months Year-on-year growth — earnings +4088.2%.
- 5-Year Trend Long-term compounding — revenue CAGR -41.9%.
Growth & Price Performance
Compounded Sales Growth
| 5 Years: | -41.88% |
| 1 Year: | - |
Compounded Profit Growth
| 5 Years: | - |
| 1 Year: | 4,088.24% |
Stock Price Performance
| 1 Year: | -65.18% |
| 6 Months: | -40.34% |
| 3 Months: | -11.46% |
| 1 Month: | +14.17% |
Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.
- Price vs 50-DMAAbove
- Price vs 200-DMABelow
- RSI (14)58.51 · Neutral
Auto-generated from price history and fundamentals; not investment advice.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth Charts
No fundamental data available for this stock.
Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.
PROS
No notable strengths flagged.
CONS
- Revenue declined at -41.9% CAGR over 5 years.
- Trading 80.6% below its 52-week high.
- In a downtrend (50-DMA below 200-DMA).
* The pros and cons are auto-generated from financial metrics.
Valuation
Growth (CAGR)
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | MCRB Seres Therapeutics, Inc. PHARMA | 5.56 | -2.30 | $55.85M | 0.00% | -79.05% | -66.57% | -41.88% | - |
| 2 | LLY Eli Lilly and Company SPXR3KPHARMA | 1,123.91 | 37.80 | $1.00T | 0.60% | - | 102.29% | 7.20% | 11.41% |
| 3 | JNJ Johnson & Johnson SPXR3KPHARMA | 269.12 | 31.22 | $648.55B | 1.98% | 14.88% | 25.74% | 2.43% | 4.76% |
| 4 | ABBV AbbVie Inc. SPXR3KPHARMA | 248.78 | 70.48 | $439.62B | 2.78% | 10.47% | -129.24% | 1.75% | -29.06% |
| 5 | MRK Merck & Co., Inc. SPXR3KPHARMA | 148.46 | 118.77 | $366.28B | 2.31% | - | 6.96% | 5.64% | 10.01% |
| 6 | UNH UnitedHealth Group Incorporated SPXR3KPHARMA | 400.84 | 25.74 | $359.79B | 2.47% | 9.74% | 14.15% | 10.40% | 5.43% |
| 7 | NVS Novartis AG PHARMA | 137.70 | 20.80 | $261.73B | 3.36% | 21.09% | 30.35% | 9.25% | 26.22% |
| 8 | AZN AstraZeneca PLC NDXPHARMA | 160.04 | 23.99 | $248.20B | 2.00% | 15.97% | 21.96% | 9.82% | 45.96% |
| 9 | TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA | 603.02 | 32.49 | $222.97B | 0.29% | 8.14% | 13.51% | 8.81% | 12.95% |
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios
Quarterly Results
Figures in USD.
| Metric | Sep 2015 | Dec 2015 | Mar 2016 | Jun 2016 | Sep 2016 | Dec 2016 | Mar 2017 | Jun 2017 | Sep 2017 | Dec 2017 | Mar 2018 | Jun 2018 | Sep 2018 | Dec 2018 | Mar 2019 | Jun 2019 | Sep 2019 | Dec 2019 | Mar 2020 | Jun 2020 | Sep 2020 | Mar 2021 | Jun 2021 | Sep 2021 | Mar 2022 | Jun 2022 | Sep 2022 | Mar 2023 | Jun 2023 | Sep 2023 | Mar 2024 | Jun 2024 | Sep 2024 | Dec 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 | Jun 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | 3.01M | - | - | 3.77M | 4.27M | 8.68M | - | 6.62M | 10.45M | 4.84M | - | 5.46M | 5.19M | 80.00K | 4.65M | 5.26M | 126.72M | 1.49M | 1.22M | 3.44M | - | - | - | - | - | - | - | 0 | 0 | 0 | 789.00K | 358.00K | - |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 3.53M | 1.69M | 736.00K | 592.00K | 0 | - |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -3.53M | -1.69M | -736.00K | 197.00K | 358.00K | - |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 23.71M | 23.19M | 21.74M | 19.57M | 21.27M | - |
| Operating Income | -14.56M | -19.79M | -19.92M | -28.14M | -19.09M | -25.69M | -25.89M | -28.42M | -7.31M | -29.77M | -28.27M | -28.14M | -22.21M | -21.67M | -24.55M | -10.95M | -17.18M | -19.19M | -19.69M | -20.55M | -30.00M | -35.33M | -48.14M | 68.41M | -55.75M | -63.33M | -59.11M | -70.57M | 49.52M | -44.59M | -34.44M | -28.87M | -29.17M | - | -27.24M | -24.88M | -22.48M | -19.38M | -20.91M | -21.27M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -26.16M | -18.80M | -21.43M | 81.24M | -20.13M | - |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | - | - | - | - |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 32.68M | -19.86M | 8.20M | -15.34M | -19.91M | - |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Net Income | -14.62M | -19.63M | -19.70M | -27.91M | -18.69M | -25.27M | -25.47M | -28.02M | -6.93M | -28.95M | -27.92M | -27.79M | -21.95M | -21.29M | -24.33M | -10.76M | -16.41M | -18.78M | -19.88M | -20.71M | -30.28M | -35.47M | -48.33M | 68.22M | -56.62M | -64.73M | -60.00M | -71.17M | 46.55M | -47.85M | -40.13M | -32.87M | 88.78M | - | 32.68M | -19.86M | 8.20M | -15.34M | -19.91M | 4.58M |
| Diluted EPS | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -0.36 | - | -0.53 | 0.72 | -0.61 | -0.70 | -0.49 | -0.57 | 0.36 | -0.37 | -5.49 | -4.34 | 11.63 | - | 3.75 | -2.27 | 0.94 | - | -2.08 | 0.47 |
| R&D Expense | 9.85M | - | 15.42M | 22.17M | 24.14M | - | 20.14M | 23.06M | 22.21M | - | 23.46M | 24.05M | 23.68M | - | 22.89M | 17.91M | 18.32M | - | 21.74M | 20.10M | 23.86M | 29.30M | 35.95M | 39.88M | 39.65M | 43.94M | 43.12M | 43.97M | 46.79M | 25.15M | 19.49M | 15.81M | 16.46M | - | 11.82M | 12.94M | 12.62M | - | 13.20M | 9.14M |
Profit & Loss (Annual)
Figures in USD.
| Metric | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | 0 | 21.77M | 32.10M | 26.92M | 27.19M | 11.90M | 143.86M | 7.13M | 0 | 0 | 789.00K |
| Operating Income | -6.05M | -15.08M | -54.86M | -92.84M | -91.39M | -100.28M | -71.88M | -88.13M | -64.49M | -179.91M | -195.10M | -121.31M | -93.97M |
| Net Income | -6.10M | -16.71M | -54.78M | -91.58M | -89.38M | -98.94M | -70.28M | -89.13M | -65.58M | -250.16M | -113.72M | 136.00K | 5.70M |
| Diluted EPS | - | - | - | - | - | - | - | -1.12 | -0.72 | -2.31 | -17.77 | 0.00 | 0.64 |
| R&D Expense | 4.80M | 10.72M | 38.09M | 81.99M | 89.45M | 95.95M | 80.14M | 90.57M | 141.89M | 109.65M | 117.60M | 64.60M | 49.06M |
Balance Sheet (Annual)
Figures in USD.
| Metric | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | - | - | 117.34M | 216.90M | 272.65M | 189.52M | 120.47M | 132.44M | 342.94M | - | 348.78M | 358.60M | 139.81M | 138.19M |
| Current Assets | - | - | - | - | - | - | - | - | - | - | 194.76M | 175.41M | 38.67M | 49.38M |
| Cash & Equivalents | 6.21M | 1.65M | 114.19M | 73.93M | 54.54M | 36.09M | 85.82M | 65.13M | 116.05M | - | 163.03M | 127.97M | 30.79M | 45.77M |
| Inventory | - | - | - | - | - | - | - | - | - | - | 0 | 29.65M | - | - |
| Receivables | - | - | - | - | - | - | - | - | - | 0 | - | 0 | 2.07M | 517.00K |
| Total Liabilities | - | - | 7.99M | 11.51M | 140.01M | 128.82M | 168.52M | 180.76M | 168.19M | - | 338.00M | 403.46M | 126.03M | 93.97M |
| Current Liabilities | - | - | 5.10M | 10.92M | 30.46M | 31.62M | 42.04M | 45.99M | 46.41M | - | 85.60M | 98.66M | 41.22M | 19.32M |
| Long Term Debt | - | - | - | - | - | - | - | 25.00M | 25.00M | 24.64M | 50.59M | 101.54M | - | - |
| Total Debt | - | - | - | - | - | - | - | - | - | - | 162.59M | 198.78M | 91.64M | 82.97M |
| Total Equity | -4.35M | -11.12M | -26.72M | 205.39M | 132.63M | 60.70M | -48.05M | -48.32M | 174.75M | - | 10.78M | -44.86M | 13.78M | 44.22M |
| Shares Outstanding | - | - | - | - | - | - | - | - | - | - | 6.26M | 6.75M | 8.65M | 9.56M |
Cash Flows (Annual)
Figures in USD.
| Metric | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | - | - | - | 43.92M | -75.52M | -62.85M | -76.52M | -93.61M | 6.69M | -228.82M | -117.35M | -148.61M | 1.12M |
| Investing Cash Flow | - | - | - | -65.59M | 55.70M | 112.32M | -30.52M | -158.89M | 64.09M | 82.43M | 10.58M | 142.29M | -42.00K |
| Financing Cash Flow | - | - | - | 2.14M | 83.00K | 268.00K | 86.23M | 303.42M | 1.18M | 129.60M | 71.70M | -90.37M | 13.90M |
| Capital Expenditure | -174.00K | -1.00M | -4.36M | -21.49M | -4.68M | -1.94M | -1.00M | -591.00K | -9.57M | -9.82M | -7.97M | -380.00K | -252.00K |
| Free Cash Flow | - | - | - | 22.43M | -80.20M | -64.79M | -77.52M | -94.20M | -2.88M | -238.64M | -125.33M | -148.99M | 865.00K |
| Share Buybacks | - | - | - | - | 33.00K | - | - | - | - | - | - | - | - |
Ratios (Annual)
Figures in %.
| Metric | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Operating Margin % | - | - | - | -426.5% | -284.7% | -372.6% | -264.4% | -740.8% | -44.8% | -2,524.0% | - | - | -11,910.1% |
| Net Margin % | - | - | - | -420.7% | -278.4% | -367.6% | -258.5% | -749.2% | -45.6% | -3,509.5% | - | - | 721.9% |
| ROE % | 54.9% | 62.5% | -26.7% | -69.0% | -147.3% | 205.9% | 145.4% | -51.0% | - | -2,319.9% | 253.5% | 1.0% | 12.9% |
| ROCE % | - | -13.4% | -26.6% | -38.3% | -57.9% | -127.9% | -83.1% | -29.7% | - | -68.4% | -75.1% | -123.1% | -79.1% |
Shareholding Pattern
Top Institutional Holders
| # | Holder | % Held | Shares | Value |
|---|---|---|---|---|
| 1 | Flagship Pioneering LLC | 11.51% | 1.16M | $4.62M |
| 2 | Vanguard Capital Management LLC | 2.86% | 287.78K | $1.15M |
| 3 | Marshall Wace LLP | 1.71% | 172.25K | $688.98K |
| 4 | Vontobel Holding Limited | 1.22% | 122.97K | $491.90K |
| 5 | Blackrock Inc. | 1.11% | 111.00K | $444.00K |
| 6 | Geode Capital Management, LLC | 0.80% | 79.97K | $319.90K |
| 7 | Susquehanna International Group, LLP | 0.58% | 58.33K | $233.31K |
| 8 | Vanguard Fiduciary Trust Co | 0.48% | 48.69K | $194.74K |
| 9 | State Street Corporation | 0.34% | 33.90K | $135.60K |
| 10 | Lion Point Capital, LP | 0.31% | 31.57K | $126.28K |
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
Latest News
Recent headlines for MCRB
Two new hires get options on 4,200 Seres shares - Stock Titan
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The Technical Signals Behind (MCRB) That Institutions Follow - Stock Traders Daily
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Seres Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - The Manila Times
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MCRB - Finviz
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MCRB Stock Declines As Seres Therapeutics Pauses SER-155 Phase 2 Study And Shrinks Headcount By 30% - Stocktwits
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We're A Little Worried About Seres Therapeutics' (NASDAQ:MCRB) Cash Burn Rate - finance.yahoo.com
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MCRB — Frequently Asked Questions
What is the current share price of Seres Therapeutics, Inc. (MCRB)?
As of 2026-09-19 21:16 PDT, Seres Therapeutics, Inc. (MCRB) trades at $5.56 on NasdaqGS. Its 52-week range is $4.34 to $28.63.
What is the market capitalisation of MCRB?
Seres Therapeutics, Inc. (MCRB) has a market capitalisation of $55.85M on NasdaqGS.
What is the P/E ratio of MCRB?
MCRB trades at a trailing price-to-earnings (P/E) ratio of -2.30. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 1.14.
What is the return on equity (ROE) of MCRB?
MCRB has a return on equity (ROE) of -66.57%. Its return on capital employed (ROCE) is -79.05%.
Is MCRB a good stock to buy?
This page provides a data-driven analysis of Seres Therapeutics, Inc. (MCRB), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.