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Seres Therapeutics, Inc. MCRB PHARMA

Healthcare · Biotechnology · United States
https://www.serestherapeutics.com
Company Profile ↓
$5.56
-65.18% 1Y
Mkt Cap$55.85M
P/E-2.30
P/B1.14
52W High$28.63
52W Low$4.34
Book Value$3.51
EPS (TTM)$-2.42

Company Overview

Seres Therapeutics, Inc., a clinical-stage company, focuses on developing biotherapeutics for serious diseases. The company develops SER-155, an investigational oral live biotherapeutic to decolonize GI pathogens, enhance GI epithelial barrier integrity, and regulate immune response to prevent bacterial bloodstream infections, as well as other pathogen-associated negative clinical outcomes in patients undergoing allogeneic hematopoietic stem cell transplantation. It also develops SER-603, a LBP candidate optimized to treat disruptions in the GI microbiome and to improve GI mucosal barrier integrity through the inhibition of inflammatory bacteria and associated metabolites; and SER-147, a live biotherapeutic composition to prevent bacterial bloodstream and spontaneous bacterial peritonitis infections in patients with metabolic disease, including chronic liver disease. The company was formerly known as Seres Health, Inc. and changed its name to Seres Therapeutics, Inc. in May 2015. Seres Therapeutics, Inc. was incorporated in 2010 and is headquartered in Cambridge, Massachusetts.

Recent Developments

  • Trailing 12 Months Year-on-year growth — earnings +4088.2%.
  • 5-Year Trend Long-term compounding — revenue CAGR -41.9%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-41.88%
1 Year:-

Compounded Profit Growth

5 Years:-
1 Year:4,088.24%

Stock Price Performance

1 Year:-65.18%
6 Months:-40.34%
3 Months:-11.46%
1 Month:+14.17%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Mixed
52-Week Range 5% of range
$4.34 $28.63
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMABelow
  • RSI (14)58.51 · Neutral
Price Performance
1M+14.17%
3M-11.46%
6M-40.34%
1Y-65.18%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Revenue declined at -41.9% CAGR over 5 years.
  • Trading 80.6% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-2.30
Industry PE
24.83
Forward P/E
-1.12
PEG Ratio
-
Book Value
$3.51
Price to Book
1.14
P/S
21.34
EV/EBITDA
-1.08
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-41.88%
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
4,088.24%

Profitability & Returns

ROCE
-79.05%
ROE
-66.57%
ROA
-39.85%
Profit Margin
0.00%
Op Margin
-
Gross Margin
0.00%
EPS (Latest Qtr)
$0.47
EPS (TTM)
$-2.42

Balance Sheet & Liquidity

Debt/Equity
1.64
Quick Ratio
2.04
Current Ratio
2.11
Debt
$56.64M
Total Assets
$101.59M
Current Assets
$49.38M
Working Capital
$30.05M

Ownership

Promoter Holding
11.49%
Chg in Prom Hold
0.01%
FII / Inst Holding
22.99%
Chg in FII Hold
-0.04%

Financial Snapshot

Enterprise Value
$55.85M
Total Revenue (TTM)
$1.88M
EBITDA
$-74.78M
Free Cash Flow
$-64.60M
Operating Cash Flow
$-51.26M
Shares Outstanding
10.04M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 MCRB Seres Therapeutics, Inc. PHARMA 5.56 -2.30 $55.85M 0.00% -79.05% -66.57% -41.88% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue -------3.01M--3.77M4.27M8.68M-6.62M10.45M4.84M-5.46M5.19M80.00K4.65M5.26M126.72M1.49M1.22M3.44M-------000789.00K358.00K-
Cost of Revenue ----------------------------------3.53M1.69M736.00K592.00K0-
Gross Profit -----------------------------------3.53M-1.69M-736.00K197.00K358.00K-
Operating Expenses ----------------------------------23.71M23.19M21.74M19.57M21.27M-
Operating Income -14.56M-19.79M-19.92M-28.14M-19.09M-25.69M-25.89M-28.42M-7.31M-29.77M-28.27M-28.14M-22.21M-21.67M-24.55M-10.95M-17.18M-19.19M-19.69M-20.55M-30.00M-35.33M-48.14M68.41M-55.75M-63.33M-59.11M-70.57M49.52M-44.59M-34.44M-28.87M-29.17M--27.24M-24.88M-22.48M-19.38M-20.91M-21.27M
EBITDA -----------------------------------26.16M-18.80M-21.43M81.24M-20.13M-
Interest Expense ---------------------------------000----
Pretax Income ----------------------------------32.68M-19.86M8.20M-15.34M-19.91M-
Tax Provision ----------------------------------------
Net Income -14.62M-19.63M-19.70M-27.91M-18.69M-25.27M-25.47M-28.02M-6.93M-28.95M-27.92M-27.79M-21.95M-21.29M-24.33M-10.76M-16.41M-18.78M-19.88M-20.71M-30.28M-35.47M-48.33M68.22M-56.62M-64.73M-60.00M-71.17M46.55M-47.85M-40.13M-32.87M88.78M-32.68M-19.86M8.20M-15.34M-19.91M4.58M
Diluted EPS ---------------------0.36--0.530.72-0.61-0.70-0.49-0.570.36-0.37-5.49-4.3411.63-3.75-2.270.94--2.080.47
R&D Expense 9.85M-15.42M22.17M24.14M-20.14M23.06M22.21M-23.46M24.05M23.68M-22.89M17.91M18.32M-21.74M20.10M23.86M29.30M35.95M39.88M39.65M43.94M43.12M43.97M46.79M25.15M19.49M15.81M16.46M-11.82M12.94M12.62M-13.20M9.14M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue --021.77M32.10M26.92M27.19M11.90M143.86M7.13M00789.00K
Operating Income -6.05M-15.08M-54.86M-92.84M-91.39M-100.28M-71.88M-88.13M-64.49M-179.91M-195.10M-121.31M-93.97M
Net Income -6.10M-16.71M-54.78M-91.58M-89.38M-98.94M-70.28M-89.13M-65.58M-250.16M-113.72M136.00K5.70M
Diluted EPS --------1.12-0.72-2.31-17.770.000.64
R&D Expense 4.80M10.72M38.09M81.99M89.45M95.95M80.14M90.57M141.89M109.65M117.60M64.60M49.06M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --117.34M216.90M272.65M189.52M120.47M132.44M342.94M-348.78M358.60M139.81M138.19M
Current Assets ----------194.76M175.41M38.67M49.38M
Cash & Equivalents 6.21M1.65M114.19M73.93M54.54M36.09M85.82M65.13M116.05M-163.03M127.97M30.79M45.77M
Inventory ----------029.65M--
Receivables ---------0-02.07M517.00K
Total Liabilities --7.99M11.51M140.01M128.82M168.52M180.76M168.19M-338.00M403.46M126.03M93.97M
Current Liabilities --5.10M10.92M30.46M31.62M42.04M45.99M46.41M-85.60M98.66M41.22M19.32M
Long Term Debt -------25.00M25.00M24.64M50.59M101.54M--
Total Debt ----------162.59M198.78M91.64M82.97M
Total Equity -4.35M-11.12M-26.72M205.39M132.63M60.70M-48.05M-48.32M174.75M-10.78M-44.86M13.78M44.22M
Shares Outstanding ----------6.26M6.75M8.65M9.56M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow ---43.92M-75.52M-62.85M-76.52M-93.61M6.69M-228.82M-117.35M-148.61M1.12M
Investing Cash Flow ----65.59M55.70M112.32M-30.52M-158.89M64.09M82.43M10.58M142.29M-42.00K
Financing Cash Flow ---2.14M83.00K268.00K86.23M303.42M1.18M129.60M71.70M-90.37M13.90M
Capital Expenditure -174.00K-1.00M-4.36M-21.49M-4.68M-1.94M-1.00M-591.00K-9.57M-9.82M-7.97M-380.00K-252.00K
Free Cash Flow ---22.43M-80.20M-64.79M-77.52M-94.20M-2.88M-238.64M-125.33M-148.99M865.00K
Share Buybacks ----33.00K--------

Ratios (Annual)

Figures in %.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -------------
Operating Margin % ----426.5%-284.7%-372.6%-264.4%-740.8%-44.8%-2,524.0%---11,910.1%
Net Margin % ----420.7%-278.4%-367.6%-258.5%-749.2%-45.6%-3,509.5%--721.9%
ROE % 54.9%62.5%-26.7%-69.0%-147.3%205.9%145.4%-51.0%--2,319.9%253.5%1.0%12.9%
ROCE % --13.4%-26.6%-38.3%-57.9%-127.9%-83.1%-29.7%--68.4%-75.1%-123.1%-79.1%

Shareholding Pattern

Insiders
11.49%
Institutions
22.99%
Public Float
25.97%

Top Institutional Holders

#Holder% HeldSharesValue
1 Flagship Pioneering LLC 11.51% 1.16M $4.62M
2 Vanguard Capital Management LLC 2.86% 287.78K $1.15M
3 Marshall Wace LLP 1.71% 172.25K $688.98K
4 Vontobel Holding Limited 1.22% 122.97K $491.90K
5 Blackrock Inc. 1.11% 111.00K $444.00K
6 Geode Capital Management, LLC 0.80% 79.97K $319.90K
7 Susquehanna International Group, LLP 0.58% 58.33K $233.31K
8 Vanguard Fiduciary Trust Co 0.48% 48.69K $194.74K
9 State Street Corporation 0.34% 33.90K $135.60K
10 Lion Point Capital, LP 0.31% 31.57K $126.28K

Analyst View

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Latest News

Recent headlines for MCRB

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Two new hires get options on 4,200 Seres shares - Stock Titan

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Google News hu, 05 Mar 2026

MCRB Stock Declines As Seres Therapeutics Pauses SER-155 Phase 2 Study And Shrinks Headcount By 30% - Stocktwits

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MCRB — Frequently Asked Questions

What is the current share price of Seres Therapeutics, Inc. (MCRB)?

As of 2026-09-19 21:16 PDT, Seres Therapeutics, Inc. (MCRB) trades at $5.56 on NasdaqGS. Its 52-week range is $4.34 to $28.63.

What is the market capitalisation of MCRB?

Seres Therapeutics, Inc. (MCRB) has a market capitalisation of $55.85M on NasdaqGS.

What is the P/E ratio of MCRB?

MCRB trades at a trailing price-to-earnings (P/E) ratio of -2.30. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 1.14.

What is the return on equity (ROE) of MCRB?

MCRB has a return on equity (ROE) of -66.57%. Its return on capital employed (ROCE) is -79.05%.

Is MCRB a good stock to buy?

This page provides a data-driven analysis of Seres Therapeutics, Inc. (MCRB), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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