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Ligand Pharmaceuticals Incorporated LGND R2K

Healthcare · Biotechnology · United States
https://www.ligand.com
Company Profile ↓
$300.97
+137.13% 1Y
Mkt Cap$6.03B
P/E39.19
P/B5.13
52W High$322.61
52W Low$124.30
Book Value$49.79
EPS (TTM)$7.68

Company Overview

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, develops and licenses biopharmaceutical assets worldwide. It offers Pradefovir, Posaconazole, Voriconazole, CAPVAXIVE, NOXAFIL, MenFive, and ZELSUVMI for infectious disease; EVOMELA and KYPROLIS for multiple myeloma; FILSPARI for the treatment of immunoglobulin a nephropathy; PNEUMOSIL, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia in children; and QARZIBA to treat neuroblastoma. The company also provides Teriparatide injection product for osteoporosis; RYLAZE, a recombinant erwinia asparaginase for acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes in adults and children aged 8 years and older with Stage 2 T1D; and VAXNEUVANCE for the prevention of invasive disease caused by streptococcus pneumoniae serotypes. In addition, it offers Duavee for menopause; Frovatriptan to treat Neurology; FYCOMPA and SESQUIENT for CNS; MEKINIST for cardiology; Nexterone, a captisol-enabled formulation of amiodarone; VEKLURY, an antiviral treatment for COVID-19; and Viviant for osteoporosis. Further, the company develops ACLX-002, Ciforadenant, UGN-301, Viright, MB07133, BOT/BAL, and Lasofoxifene for oncology; Ensifentrine for respiratory disease; QTORIN for rare disease; Sparsentan for kidney disease; VK2809 for hepatology; ANEB-001 for acute cannabinoid intoxication; Reproxalap for opthamology; VK0214 for Rare Disease; and VK5211 for musculoskeletal disorder. The company was incorporated in 1987 and is based in Jupiter, Florida.

Why Investors Should Care

Strong Return on Equity

Generates a return on equity of 17.1%, reflecting efficient use of shareholder capital.

Steady Revenue Expansion

Revenue has grown at a 12.8% CAGR over the past five years.

Healthy Margins

Maintains a net profit margin of 55.9%.

Positive Free Cash Flow

Generates positive free cash flow, funding growth and shareholder returns internally.

Recent Developments

  • Dec 2025 Revenue of $268.09M (+60.4% YoY); net profit $124.45M.
  • Trailing 12 Months Year-on-year growth — revenue +14.1%.
  • 5-Year Trend Long-term compounding — revenue CAGR 12.8%.

Growth & Price Performance

Compounded Sales Growth

5 Years:12.82%
1 Year:14.10%

Stock Price Performance

1 Year:+137.13%
6 Months:+45.64%
3 Months:+41.01%
1 Month:+18.23%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 89% of range
$124.30 $322.61
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)58.35 · Neutral
Price Performance
1M+18.23%
3M+41.01%
6M+45.64%
1Y+137.13%
Valuation vs Sector

P/E of 39.19 is above the sector median of 25.41 — pricier than peers.

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Excellent profit margin of 55.9%.
  • Compounding revenue at 12.8% over 5 years.
  • Generates positive free cash flow.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
39.19
Industry PE
25.41
Forward P/E
26.60
PEG Ratio
1.53
Book Value
$49.79
Price to Book
5.13
P/S
18.66
EV/EBITDA
35.66
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
12.82%
Profit 5Y
-
Revenue (YoY)
14.10%
Earnings (YoY)
-

Profitability & Returns

ROCE
2.69%
ROE
17.13%
ROA
5.19%
Profit Margin
55.95%
Op Margin
33.58%
Gross Margin
83.16%
EPS (Latest Qtr)
$-0.67
EPS (TTM)
$7.68

Balance Sheet & Liquidity

Debt/Equity
0.45
Quick Ratio
20.81
Current Ratio
21.28
Debt
$451.98M
Total Assets
$1.53B
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
2.37%
Chg in Prom Hold
-0.01%
FII / Inst Holding
106.29%
Chg in FII Hold
-0.07%

Financial Snapshot

Enterprise Value
$6.03B
Total Revenue (TTM)
$274.48M
EBITDA
$134.45M
Free Cash Flow
$142.11M
Operating Cash Flow
$123.50M
Shares Outstanding
20.04M
Gross Margin
83.16%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 LGND Ligand Pharmaceuticals Incorporated R2K 300.97 39.19 $6.03B 0.00% 2.69% 17.13% 12.82% -
2 LLY Eli Lilly and Company SPX 1,152.54 41.02 $1.03T 0.61% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 253.85 29.45 $611.07B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.78 119.40 $432.48B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 425.19 32.02 $386.13B 2.27% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 120.78 34.02 $298.31B 2.86% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 164.50 24.81 $255.12B 1.77% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 534.07 29.33 $198.47B 0.40% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 355.25 24.69 $191.73B 2.84% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Dec 2021Mar 2022Jun 2022Sep 2022Dec 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue ------56.16M90.04M45.66M59.59M56.16M90.04M45.66M59.59M43.48M24.99M24.81M27.00M33.16M41.42M41.85M69.99M46.59M78.85M59.69M56.40M36.52M50.13M59.22M50.38M43.98M26.37M32.87M30.98M41.53M51.81M45.33M47.63M115.46M51.72M
Operating Income 8.60M-15.10M3.97M5.47M-10.22M13.02M16.49M-37.04M70.17M23.36M-826.54M-4.13M-5.16M-3.79M7.10M3.75M-4.71M45.74M15.71M-2.13M8.66M12.34M-14.21M-1.98M3.08M2.99M-19.10M3.14M-36.22M8.44M54.93M17.37M
Net Income 199.16M6.34M6.61M-6.17M1.05M-3.12M45.28M73.16M67.36M-42.48M45.28M73.16M67.36M-42.48M666.34M-14.42M-15.25M-7.37M-24.13M22.09M-6.70M5.76M18.11M30.73M13.72M-5.42M-15.38M-895.00K404.00K-17.48M41.95M2.29M-10.27M86.14M-51.91M-7.17M-42.45M4.85M117.27M-13.35M
Diluted EPS 9.280.290.30-0.300.050.151.832.992.80-2.021.832.992.80-2.0231.32-0.74-0.81-0.43-1.461.32-0.420.351.051.790.80--0.91-0.050.02-2.330.13-0.594.75-2.88-0.39-2.210.245.68-0.67
R&D Expense 1.95M-4.00M4.91M5.90M-8.67M4.82M4.76M-7.41M6.13M5.48M-11.29M12.21M13.74M-11.89M12.73M12.85M-9.05M7.48M7.43M8.15M9.18M8.47M9.24M9.20M6.66M6.85M5.53M5.97M5.35M5.67M50.09M6.57M21.02M2.15M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 38.94M23.54M30.04M31.39M48.97M64.54M71.91M108.97M141.10M251.45M120.28M163.56M241.54M196.25M131.31M167.13M268.09M
Operating Income -9.97M-29.30M-878.00K193.00K14.94M19.63M27.33M43.88M68.08M163.73M807.08M37.50M103.85M3.04M11.94M-22.61M41.00M
Net Income -1.95M-10.37M9.71M-527.00K11.42M12.02M229.82M-1.64M12.56M143.32M629.30M-2.98M57.14M-33.36M52.15M-4.03M124.45M
Diluted EPS --0.49-0.030.550.5610.83-0.080.535.9631.85-0.183.31-1.982.94-0.226.13
R&D Expense 39.87M22.07M10.29M10.79M9.27M9.75M11.01M21.22M26.89M27.86M55.91M40.50M32.10M36.08M24.54M21.43M81.18M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2008Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --75.56M120.58M104.26M104.71M258.03M503.06M601.59M671.02M1.26B1.49B1.36B1.30B762.67M787.22M941.77M1.56B
Total Equity -10.37M3.74M-4.85M8.19M26.48M49.61M26.32M237.28M341.29M399.79M560.91M767.23M709.52M821.16M597.49M700.91M830.44M1.02B
Cash & Equivalents 28.75M16.03M3.35M7.04M12.38M11.64M160.20M97.43M18.75M20.62M117.16M71.54M47.62M19.52M45.01M22.95M72.31M174.93M
Long Term Debt ----27.50M-------------
Total Liabilities --72.06M104.05M77.78M55.10M233.62M226.15M230.73M252.37M699.89M727.68M652.76M476.43M165.18M86.30M111.33M543.42M
Current Liabilities --33.49M43.64M35.44M28.94M22.78M222.82M227.13M238.87M82.25M17.00M100.11M41.66M98.81M16.78M37.11M37.45M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -33.80M-27.07M-1.17M161.00K20.69M20.57M41.73M60.73M88.57M194.06M-29.34M54.59M78.80M137.85M49.58M97.05M49.36M
Investing Cash Flow 24.77M14.54M-25.13M1.26M-4.97M-2.03M-112.86M-134.41M-79.18M-423.27M466.92M231.65M30.52M163.62M-11.68M-143.66M-377.32M
Financing Cash Flow -3.69M-159.00K30.00M3.92M-16.46M130.03M8.36M-4.99M-7.52M328.58M-485.17M-310.55M-137.76M-275.99M-59.95M97.14M428.22M
Capital Expenditure -522.00K-70.00K-78.00K-595.00K-377.00K-6.00K-93.00K-1.85M-2.16M-887.00K-2.55M-4.46M-8.76M-17.92M-3.52M-1.82M-452.00K
Free Cash Flow -34.32M-27.14M-1.25M-434.00K20.31M20.56M41.63M58.88M86.41M193.17M-31.89M50.13M70.04M119.93M46.06M95.23M48.91M
Share Buybacks -91.00K55.00K0067.95M489.00K3.90M1.97M122.87M453.05M78.00M000015.00M

Ratios (Annual)

Figures in %.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----------------
Operating Margin % -25.6%-124.5%-2.9%0.6%30.5%30.4%38.0%40.3%48.2%65.1%671.0%22.9%43.0%1.5%9.1%-13.5%15.3%
Net Margin % -5.0%-44.1%32.3%-1.7%23.3%18.6%319.6%-1.5%8.9%57.0%523.2%-1.8%23.7%-17.0%39.7%-2.4%46.4%
ROE % -52.0%213.9%118.7%-2.0%23.0%45.7%96.9%-0.5%3.1%25.6%82.0%-0.4%7.0%-5.6%7.4%-0.5%12.2%
ROCE % --69.7%-1.1%0.3%19.7%8.3%9.8%11.7%15.8%13.9%54.6%3.0%8.3%0.5%1.6%-2.5%2.7%

Shareholding Pattern

Insiders
2.37%
Institutions
106.29%
Public Float
108.87%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 14.78% 2.96M $944.82M
2 Vanguard Portfolio Management LLC 5.49% 1.10M $350.97M
3 Janus Henderson Group PLC 5.04% 1.01M $322.15M
4 Vanguard Capital Management LLC 4.23% 848.09K $270.53M
5 Invesco Ltd. 4.11% 823.60K $262.72M
6 State Street Corporation 3.89% 778.86K $248.45M
7 FMR, LLC 2.97% 596.13K $190.16M
8 Franklin Resources, Inc. 2.86% 573.18K $182.84M
9 Nomura Asset Management International Inc 2.86% 573.31K $182.88M
10 Chicago Capital, LLC 2.80% 561.67K $179.17M

Analyst View

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Latest News

Recent headlines for LGND

Google News ue, 14 Jul 2026

Ligand’s Portfolio Now Tops 200 Biopharmaceutical Royalty Assets - Stock Titan

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TVTX, LGND Stocks In Spotlight Ahead Of Monday’s FDA Call On Kidney Drug Filspari - Stocktwits

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Google News ue, 14 Jul 2026

Ligand completes $739M acquisition of XOMA Royalty Corporation - Investing.com

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Google News ue, 23 Jun 2026

LGND Stock Draws Traders As Royalties Rise, Debt Deal Hits - StocksToTrade

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Google News hu, 09 Jul 2026

LGND Maintained by B of A Securities -- Price Target Raised to $388 - GuruFocus

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LGND — Frequently Asked Questions

What is the current share price of Ligand Pharmaceuticals Incorporated (LGND)?

As of 2026-07-14 21:23 PDT, Ligand Pharmaceuticals Incorporated (LGND) trades at $300.97 on NasdaqGM. Its 52-week range is $124.30 to $322.61.

What is the market capitalisation of LGND?

Ligand Pharmaceuticals Incorporated (LGND) has a market capitalisation of $6.03B on NasdaqGM.

What is the P/E ratio of LGND?

LGND trades at a trailing price-to-earnings (P/E) ratio of 39.19. The industry average P/E is 25.41. Its price-to-book (P/B) ratio is 5.13.

What is the return on equity (ROE) of LGND?

LGND has a return on equity (ROE) of 17.13%. Its return on capital employed (ROCE) is 2.69%.

Is LGND a good stock to buy?

This page provides a data-driven analysis of Ligand Pharmaceuticals Incorporated (LGND), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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