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$1.91
-52.49% 1Y
P/E-0.11
52W High$10.67
52W Low$1.91
EPS (TTM)$-17.93

Company Overview

KPTI (KPTI) is a publicly traded company listed on . The valuation, growth and price-trend signals below summarize what matters most to investors and traders evaluating the stock.

Why Investors Should Care

Strong Return on Equity

Generates a return on equity of 66.9%, reflecting efficient use of shareholder capital.

Steady Revenue Expansion

Revenue has grown at a 63.3% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $146.07M (+0.6% YoY); net profit $-196.04M.
  • Trailing 12 Months Year-on-year growth — revenue +0.6%.
  • 5-Year Trend Long-term compounding — revenue CAGR 63.3%.

Growth & Price Performance

Compounded Sales Growth

5 Years:63.32%
1 Year:0.57%

Stock Price Performance

1 Year:-52.49%
6 Months:-70.84%
3 Months:-79.70%
1 Month:-81.00%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 0% of range
$1.91 $10.67
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)16.31 · Oversold
Price Performance
1M-81.00%
3M-79.70%
6M-70.84%
1Y-52.49%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Strong return on equity of 66.9%.
  • Compounding revenue at 63.3% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Trading 82.1% below its 52-week high.
  • RSI at 16 suggests oversold conditions.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-0.11
Industry PE
-
Forward P/E
-
PEG Ratio
-
Book Value
$-
Price to Book
-
P/S
-
EV/EBITDA
-
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
63.32%
Profit 5Y
-
Revenue (YoY)
0.57%
Earnings (YoY)
-

Profitability & Returns

ROCE
-
ROE
66.92%
ROA
-
Profit Margin
-
Op Margin
-62.10%
Gross Margin
-
EPS (Latest Qtr)
$-1.24
EPS (TTM)
$-17.93

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
-
Current Ratio
-
Debt
-
Total Assets
$131.42M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
4.68%
Chg in Prom Hold
-
FII / Inst Holding
84.51%
Chg in FII Hold
-

Financial Snapshot

Enterprise Value
-
Total Revenue (TTM)
$146.07M
EBITDA
-
Free Cash Flow
$-75.37M
Operating Cash Flow
$-75.37M
Shares Outstanding
-
Gross Margin
-
Payout Ratio
-
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Sep 2014Dec 2014Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue -----------3.00K--10.00M19.89M239.00K-155.00K9.49M13.15M18.14M33.51M21.33M23.26M22.60M37.69M47.67M39.68M36.15M38.70M37.58M36.01M33.13M42.79M38.78M30.02M37.93M44.04M35.07M
Operating Income -19.74M-25.94M-26.15M-33.01M-30.61M-29.30M-27.35M-30.48M-25.74M-27.16M-30.28M-29.75M-31.05M-39.45M-38.94M-34.33M-49.15M-57.45M-64.92M-41.69M-39.40M-47.36M-40.32M-47.11M-52.37M-49.05M-43.81M-34.59M-42.91M-30.84M-30.90M-29.57M-31.26M-33.76M-28.12M-26.28M-33.26M-24.39M-15.22M-26.76M
Net Income -19.72M-25.93M-26.07M-32.70M-30.37M-29.05M-27.06M-30.16M-25.43M-26.93M-29.92M-29.39M-30.64M-39.04M-38.46M-33.66M-48.08M-58.21M-66.16M-43.41M-41.37M-52.93M-46.43M-53.49M-57.41M-53.58M-51.81M-41.40M-49.06M-36.32M-34.13M-32.63M-34.51M-37.36M23.79M-32.07M-23.46M-37.25M-33.13M-22.39M
Diluted EPS --------------------------0.71-0.69-0.53-0.62-0.45-0.30-0.29-0.30-4.85-2.97-3.85-2.77-4.32-3.82-1.24
R&D Expense 15.95M-20.75M27.01M25.92M-21.80M24.58M19.89M-24.08M23.12M25.24M-41.32M44.73M36.43M-37.97M26.52M26.27M34.00M42.59M37.04M37.05M33.98M45.81M42.06M44.31M31.36M32.34M31.48M35.55M35.42M38.37M36.13M34.62M32.79M30.54M33.80M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue --152.00K634.00K387.00K229.00K250.00K154.00K1.60M30.34M40.89M108.08M209.82M157.07M146.03M145.24M146.07M
Operating Income ---10.31M-15.89M-33.95M-75.85M-119.08M-110.73M-130.54M-179.88M-189.28M-171.85M-98.27M-142.20M-129.54M-119.44M-90.71M
Net Income -179.00K-2.24M-10.31M-15.89M-33.95M-75.78M-118.18M-109.58M-128.98M-178.41M-199.59M-196.27M-124.09M-165.29M-143.10M-76.42M-196.04M
Diluted EPS ------------2.72-1.65-2.02-18.79-14.00-17.93
R&D Expense --8.62M14.10M28.45M60.13M97.74M86.94M107.27M161.37M122.34M150.81M160.84M148.66M138.75M143.23M125.62M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets ---1.31M158.23M220.34M215.44M180.38M180.29M341.19M294.96M313.05M305.31M358.17M240.44M164.42M108.42M
Total Equity -179.00K-2.38M-12.65M-27.88M154.93M206.79M198.37M162.24M129.46M183.17M49.77M50.55M-79.67M-16.66M-136.21M-186.02M-292.93M
Cash & Equivalents -3.44M6.51M391.00K155.97M150.61M58.36M49.66M69.00M118.02M128.86M85.92M190.46M135.19M52.23M62.48M60.54M
Long Term Debt ------------169.29M----
Total Liabilities ----3.29M13.54M17.08M18.14M50.83M158.02M245.19M262.50M384.98M374.83M376.64M350.44M401.34M
Current Liabilities ---1.93M3.29M12.30M15.13M16.48M49.47M46.90M46.35M60.20M73.72M65.91M69.48M92.26M92.06M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow ------84.39M-73.72M-159.12M-190.82M-160.23M-107.12M-149.55M-92.72M-127.49M-75.37M
Investing Cash Flow -----24.59M17.11M-107.66M78.45M-53.69M141.84M-104.26M7.94M95.47M43.38M
Financing Cash Flow -----51.16M75.74M316.11M124.31M172.08M73.65M193.74M1.12M41.65M30.05M
Capital Expenditure -376.00K-121.00K-57.00K-2.83M-1.42M-70.00K-62.00K-2.36M-206.00K-145.00K-212.00K-118.00K-0-142.00K-0
Free Cash Flow ------84.46M-73.78M-161.48M-191.03M-160.38M-107.33M-149.67M-92.72M-127.63M-75.37M

Ratios (Annual)

Figures in %.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----------------
Operating Margin % ---6,783.6%-2,506.3%-8,772.6%-33,120.5%-47,630.4%-71,903.9%-8,133.2%-593.0%-462.9%-159.0%-46.8%-90.5%-88.7%-82.2%-62.1%
Net Margin % ---6,783.6%-2,506.0%-8,771.8%-33,090.4%-47,272.4%-71,153.9%-8,036.4%-588.1%-488.1%-181.6%-59.1%-105.2%-98.0%-52.6%-134.2%
ROE % 100.0%94.4%81.5%57.0%-21.9%-36.6%-59.6%-67.5%-99.6%-97.4%-401.0%-388.3%155.7%992.4%105.1%41.1%66.9%
ROCE % ---2,567.0%-21.9%-36.5%-59.4%-67.6%-99.8%-61.1%-76.1%-68.0%-42.4%-48.7%-75.8%-165.5%-554.6%

Shareholding Pattern

Insiders
4.68%
Institutions
84.51%
Public Float
88.66%

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for KPTI

Google News Wed, 05 Aug 2026

Why Is KPTI Stock Down 69% After-Hours Today? - Stocktwits

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Google News Fri, 31 Jul 2026

$KPTI stock is down 67% today. Here's what we see in our data. - Quiver Quantitative

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Google News hu, 25 Jun 2026

Karyopharm Therapeutics (KPTI) Stock Sees Split Analyst Revisions After Phase 3 Trial Update - Yahoo Finance

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Google News Fri, 31 Jul 2026

KPTI Stock Collapses After Trial Failure And Legal Scrutiny - StocksToTrade

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Google News Mon, 03 Aug 2026

Market Movers | Winners: FWAC, REPL, MGRX | Losers: KPTI, BIOA, MBRX - Trefis

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Google News Fri, 31 Jul 2026

Karyopharm Stock (KPTI) Crashes After Hours: Here's What's Driving the Move - TradingView

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KPTI — Frequently Asked Questions

What is the current share price of KPTI?

As of 2026-08-05 17:25 PDT, KPTI trades at $1.91 on NASDAQ/NYSE. Its 52-week range is $1.91 to $10.67.

What is the P/E ratio of KPTI?

KPTI trades at a trailing price-to-earnings (P/E) ratio of -0.11.

What is the return on equity (ROE) of KPTI?

KPTI has a return on equity (ROE) of 66.92%.

Is KPTI a good stock to buy?

This page provides a data-driven analysis of KPTI, including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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