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IDEAYA Biosciences, Inc. IDYA R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://www.ideayabio.com
Company Profile ↓
$39.86
+63.23% 1Y
Mkt Cap$3.84B
P/E-20.76
P/B3.47
52W High$42.48
52W Low$23.39
Book Value$10.67
EPS (TTM)$-1.92

Company Overview

IDEAYA Biosciences, Inc., a precision medicine oncology company, develops targeted therapeutics for patient populations selected using molecular diagnostics in the United States. The company offers Darovasertib, an oral, potent, and selective protein kinase, C (PKC) inhibitor for the treatment of uveal melanoma, ocular cancer, and is being evaluated in multiple clinical trials as monotherapy and in combination with crizotinib for metastatic, neoadjuvant, and adjuvant settings. The company also offers IDE849, a DLL3 antibody drug conjugate inhibitor for the treatment of SCLC and neuroendocrine carcinomas; IDE034, a B7H3/PTK7 topo-I-payload bispecific BsADC; IDE161, a poly ADP-ribose glycohydrolase inhibitor; IDE705 (GSK101), a Poly Theta Helicase inhibitor that is in Phase 1 clinical trial for the treatment of tumors with BRCA or other mutations associated with HRD; IDE397, a MAT2A inhibitor for MTAP-deleted tumors; IDE892, a PRMT5 inhibitor; IDE574 selectively inhibits KAT6/7 and is in Phase 1 dose escalation trial for patients with breast, lung, prostate, and colorectal cancers; IDE275 oral small molecule inhibitor of the helicase domain of the Werner protein (WRN) and is in a Phase 1 clinical trial. In addition, the company offers preclinical research programs focused on pharmacological inhibition; DECIPHER dual CRISPR library for synthetic lethality target and biomarker discovery; and INQUIRE chemical library and HARMONY machine-learning engines to enhance its drug discovery platform. The company has strategic alliances with GlaxoSmithKline, Pfizer Inc., Gilead Sciences, Inc., Novartis, Biocytogen, Cancer Research UK, the University of Manchester, Jiangsu Hengrui Pharmaceuticals Co., Ltd., and Les Laboratoires Servie. It also has a clinical collaboration agreement with AstraZeneca plc to evaluate IDE849, an antibody-drug conjugate; and clinical collaboration with Roche to evaluate IDE892, IDEAYA's potential best-in-class Phase 1 MTA-cooperative PRMT5 inhibitor, in combination with RG6505, Roche's Phase 1 pan-RAS inhibitor, in MTAP-deleted, RAS-mutant pancreatic ductal adenocarcinoma. IDEAYA Biosciences, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.

Recent Developments

  • Dec 2025 Revenue of $218.71M (+3024.4% YoY); net profit $-113.70M.
  • Trailing 12 Months Year-on-year growth — revenue +3024.4%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-
1 Year:3,024.43%

Stock Price Performance

1 Year:+63.23%
6 Months:+20.10%
3 Months:+40.90%
1 Month:+9.99%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 86% of range
$23.39 $42.48
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)57.75 · Neutral
Price Performance
1M+9.99%
3M+40.90%
6M+20.10%
1Y+63.23%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-20.76
Industry PE
25.17
Forward P/E
-10.84
PEG Ratio
-
Book Value
$10.67
Price to Book
3.47
P/S
15.22
EV/EBITDA
-12.94
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
3,024.43%
Earnings (YoY)
-

Profitability & Returns

ROCE
-15.17%
ROE
-16.22%
ROA
-11.54%
Profit Margin
-74.75%
Op Margin
-
Gross Margin
-36.41%
EPS (Latest Qtr)
$-1.22
EPS (TTM)
$-1.92

Balance Sheet & Liquidity

Debt/Equity
2.44
Quick Ratio
10.21
Current Ratio
10.45
Debt
$29.31M
Total Assets
$1.31B
Current Assets
$696.11M
Working Capital
$631.28M

Ownership

Promoter Holding
2.19%
Chg in Prom Hold
-0.03%
FII / Inst Holding
108.22%
Chg in FII Hold
0.04%

Financial Snapshot

Enterprise Value
$3.84B
Total Revenue (TTM)
$234.13M
EBITDA
$-214.20M
Free Cash Flow
$-70.85M
Operating Cash Flow
$-111.66M
Shares Outstanding
96.27M
Gross Margin
-36.41%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 IDYA IDEAYA Biosciences, Inc. R2KR3KPHARMA 39.86 -20.76 $3.84B 0.00% -15.17% -16.22% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue ----------8.97M7.25M8.76M8.98M11.36M5.85M29.70M7.88M3.54M8.04M000--207.83M-6.56M8.86M
Operating Income --7.57M-13.63M--10.09M-11.23M-11.62M--12.48M-12.59M-5.00M-9.13M-11.05M-11.71M-14.22M-22.50M660.00K-26.28M-32.71M-33.53M-51.02M-64.93M-66.89M-84.39M-88.81M108.45M--108.54M-122.29M
Net Income -5.74M-7.00M-13.05M-8.56M-9.57M-10.66M-10.97M-10.78M-12.04M-12.39M-4.93M-9.02M-10.95M-11.58M-14.01M-22.06M1.61M-23.64M-27.93M-27.44M-39.57M-52.77M-51.82M-72.18M-77.49M119.24M--98.54M-112.45M
Diluted EPS -------------0.33-0.31-0.36-0.570.04-0.49-0.50-0.46-0.53-0.68-0.60-0.82-0.881.33--1.11-1.22
R&D Expense -6.43M12.54M-8.00M8.86M8.92M-9.03M8.60M10.03M11.57M14.98M15.50M19.66M22.80M22.37M27.86M29.18M33.70M42.80M54.53M57.15M70.89M74.23M82.99M86.60M95.73M108.69M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue --019.54M-50.93M23.39M7.00M218.71M
Cost of Revenue ---------
Gross Profit ---------
Operating Expenses -----113.43M157.81M333.98M378.02M
Operating Income -14.44M-36.42M-44.27M-35.34M--62.50M-134.43M-326.98M-159.31M
EBITDA ------58.99M-130.42M-323.14M-154.72M
Interest Expense ---------
Pretax Income ------58.66M-112.96M-274.48M-113.70M
Tax Provision ---------
Net Income -11.86M-34.35M-41.98M-34.49M--58.66M-112.96M-274.48M-113.70M
Diluted EPS ----1.40--1.42-1.96-3.36-1.28
R&D Expense 12.38M31.75M34.32M39.70M58.16M89.54M129.51M294.67M314.70M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --96.54M113.00M298.27M381.35M387.97M649.32M1.12B1.11B
Total Equity -4.13M-15.74M-48.95M100.40M198.27M301.51M349.45M621.09M1.06B1.02B
Cash & Equivalents -5.96M20.50M34.07M72.04M92.05M68.63M157.02M84.38M112.83M
Total Liabilities --7.10M12.60M100.00M79.83M38.51M28.23M64.94M86.39M
Current Liabilities --5.41M6.94M38.64M45.16M31.72M27.10M46.07M58.81M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -12.22M-27.62M-39.31M55.46M-55.78M-87.17M-115.22M-247.58M-71.10M
Investing Cash Flow -8.93M-63.18M2.27M-146.24M-69.67M-33.40M-158.46M-502.56M69.98M
Financing Cash Flow 17.49M105.38M50.61M128.75M145.45M97.17M362.72M677.55M29.78M
Capital Expenditure -1.76M-1.71M-1.35M-493.00K-2.64M-3.44M-2.37M-3.86M-2.37M
Free Cash Flow -13.98M-29.33M-40.67M54.97M-58.42M-90.62M-117.59M-251.44M-73.47M

Ratios (Annual)

Figures in %.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------
Operating Margin % ----180.9%--122.7%-574.9%-4,671.1%-72.8%
Net Margin % ----176.6%--115.2%-483.0%-3,921.1%-52.0%
ROE % 75.4%70.2%-41.8%-17.4%--16.8%-18.2%-25.9%-11.1%
ROCE % --40.0%-41.7%-13.6%--17.5%-21.6%-30.3%-15.2%

Shareholding Pattern

Insiders
2.19%
Institutions
108.22%
Public Float
110.64%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 16.06% 14.11M $565.93M
2 Blackrock Inc. 10.12% 8.89M $356.71M
3 Jupiter Topco LLC 9.77% 8.58M $344.14M
4 Capital Research Global Investors 6.08% 5.34M $214.38M
5 Baker Bros. Advisors, LP 5.70% 5.01M $200.95M
6 State Street Corporation 5.18% 4.55M $182.46M
7 Vanguard Capital Management LLC 4.70% 4.13M $165.76M
8 Logos Global Management LP 3.41% 3.00M $120.33M
9 Adage Capital Partners GP L.L.C. 3.09% 2.72M $108.91M
10 Deerfield Management Company, L.P 3.09% 2.71M $108.88M

Analyst View

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Latest News

Recent headlines for IDYA

Google News Mon, 08 Jun 2026

IDEAYA Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants - PR Newswire

<a href="https://news.google.com/rss/articles/CBMi0wFBVV95cUxONFZKZG5hRFNHSWM0M1E0YjJ1R0hrUXVIUFVLU1NPLU1sT29tdkZvVDVGdmZjak51b0RYc1hITW56RjdWcEhQYi1nbU9sbU52bXdQWDNOQnc3RkxFRXNHbkZLNkNzODEwNWNQTm4ycmY3QlF6allmMkJNdnNIRFczdU5WTWZrTzBDSTRpam…

Google News ue, 01 Sep 2026

IDEAYA Biosciences Sets London R&D Day for Nov. 16 | IDYA Stock News - Stock Titan

<a href="https://news.google.com/rss/articles/CBMisAFBVV95cUxOM3JRWnp6dU1ZanNueG5sanA2LUpXdVdmTzR6bFF5N2hSM0pzbXVBNkltWks5ZmZKTEVMYi1keHpwN0N2cThOT2duZF9sZWUyV2c5dXdUM1M1cm42WmlmWmFqREZMMDRMV293VVh2aHdOWDk1Mno1WWJHWVdZbHlMU3hFTG9TZWZVcmdhSH…

Google News hu, 20 Aug 2026

IDEAYA Biosciences (IDYA) Is Up 5.2% After Genentech KRAS G12D Trial Collaboration News - Has The Bull Case Changed? - simplywall.st

<a href="https://news.google.com/rss/articles/CBMi5wFBVV95cUxOT1BjOVZLakhtaWF2WHF3NlVlT1U3TFZYSW42TE9zQXZ6QlZSckZDSVBhanZ6RTVxajVXUmZuY252Z1JuT1lnRl9Cc1hYaVhIU051bWFBLUhxN0U2VFhULU5SVFZadGtwMTZRZ0h0dl9RNmNiMF9OU3RUb3JiX25wdVBxXzgzbXd1RnBWNF…

Google News Sun, 03 May 2026

Is IDEAYA Biosciences, Inc. (IDYA) A Good Stock To Buy Now? - Yahoo Finance

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Google News hu, 25 Jun 2026

IDYA Forecast — Price Target — Prediction for 2027 - TradingView

<a href="https://news.google.com/rss/articles/CBMiekFVX3lxTE9oNWszRm5oZDZ2aUE5TjVCNEMydHRXM2p6MkZ2TTFTejBfUjVRUDM3d2x4NzZ6aDJtVUhsREdxcElUN25kNXh2dnpKSVZKT3VGbVBOTFBJenA1T0tVX0dwQllod2tSb0M5UXB2X2wxRWFoU0FZLUkzcWxR?oc=5" target="_blank">IDY…

Google News ue, 26 May 2026

IDYA - Finviz

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IDYA — Frequently Asked Questions

What is the current share price of IDEAYA Biosciences, Inc. (IDYA)?

As of 2026-09-07 16:24 PDT, IDEAYA Biosciences, Inc. (IDYA) trades at $39.86 on NasdaqGS. Its 52-week range is $23.39 to $42.48.

What is the market capitalisation of IDYA?

IDEAYA Biosciences, Inc. (IDYA) has a market capitalisation of $3.84B on NasdaqGS.

What is the P/E ratio of IDYA?

IDYA trades at a trailing price-to-earnings (P/E) ratio of -20.76. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 3.47.

What is the return on equity (ROE) of IDYA?

IDYA has a return on equity (ROE) of -16.22%. Its return on capital employed (ROCE) is -15.17%.

Is IDYA a good stock to buy?

This page provides a data-driven analysis of IDEAYA Biosciences, Inc. (IDYA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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