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IDEAYA Biosciences, Inc. IDYA R2K

Healthcare · Biotechnology · United States
https://www.ideayabio.com
Company Profile ↓
$36.74
+62.71% 1Y
Mkt Cap$3.54B
P/E-23.40
P/B3.43
52W High$40.51
52W Low$21.43
Book Value$10.67
EPS (TTM)$-1.57

Company Overview

IDEAYA Biosciences, Inc., a precision medicine oncology company, develops targeted therapeutics for patient populations selected using molecular diagnostics in the United States. The company offers Darovasertib, an oral, potent, and selective protein kinase, C (PKC) inhibitor for the treatment of uveal melanoma, ocular cancer, and is being evaluated in multiple clinical trials as monotherapy and in combination with crizotinib for metastatic, neoadjuvant, and adjuvant settings. The company also offers IDE849, a DLL3 antibody drug conjugate inhibitor for the treatment of SCLC and neuroendocrine carcinomas; IDE034, a B7H3/PTK7 topo-I-payload bispecific BsADC; IDE161, a poly ADP-ribose glycohydrolase inhibitor; IDE705 (GSK101), a Poly Theta Helicase inhibitor that is in Phase 1 clinical trial for the treatment of tumors with BRCA or other mutations associated with HRD; IDE397, a MAT2A inhibitor for MTAP-deleted tumors; IDE892, a PRMT5 inhibitor; IDE574 selectively inhibits KAT6/7 and is in Phase 1 dose escalation trial for patients with breast, lung, prostate, and colorectal cancers; IDE275 oral small molecule inhibitor of the helicase domain of the Werner protein (WRN) and is in a Phase 1 clinical trial. In addition, the company offers preclinical research programs focused on pharmacological inhibition; DECIPHER dual CRISPR library for synthetic lethality target and biomarker discovery; and INQUIRE chemical library and HARMONY machine-learning engines to enhance its drug discovery platform. The company has strategic alliances with GlaxoSmithKline, Pfizer Inc., Gilead Sciences, Inc., Novartis, Biocytogen, Cancer Research UK, the University of Manchester, Jiangsu Hengrui Pharmaceuticals Co., Ltd., and Les Laboratoires Servie. It also has a clinical collaboration agreement with AstraZeneca plc to evaluate IDE849, an antibody-drug conjugate; and clinical collaboration with Roche to evaluate IDE892, IDEAYA's potential best-in-class Phase 1 MTA-cooperative PRMT5 inhibitor, in combination with RG6505, Roche's Phase 1 pan-RAS inhibitor, in MTAP-deleted, RAS-mutant pancreatic ductal adenocarcinoma. IDEAYA Biosciences, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 62.1% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $218.71M (+3024.4% YoY); net profit $-113.70M.
  • Trailing 12 Months Year-on-year growth — revenue +3024.4%.
  • 5-Year Trend Long-term compounding — revenue CAGR 62.1%.

Growth & Price Performance

Compounded Sales Growth

5 Years:62.11%
1 Year:3,024.43%

Stock Price Performance

1 Year:+62.71%
6 Months:-0.27%
3 Months:+13.57%
1 Month:+26.78%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 80% of range
$21.43 $40.51
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)57.88 · Neutral
Price Performance
1M+26.78%
3M+13.57%
6M-0.27%
1Y+62.71%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 62.1% over 5 years.

CONS

  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-23.40
Industry PE
25.88
Forward P/E
-10.06
PEG Ratio
-
Book Value
$10.67
Price to Book
3.43
P/S
15.62
EV/EBITDA
-14.27
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
62.11%
Profit 5Y
-
Revenue (YoY)
3,024.43%
Earnings (YoY)
-

Profitability & Returns

ROCE
-15.17%
ROE
-14.28%
ROA
-10.76%
Profit Margin
-62.17%
Op Margin
-
Gross Margin
-50.73%
EPS (Latest Qtr)
$-1.11
EPS (TTM)
$-1.57

Balance Sheet & Liquidity

Debt/Equity
3.05
Quick Ratio
10.45
Current Ratio
10.74
Debt
$28.60M
Total Assets
$1.03B
Current Assets
$696.11M
Working Capital
$631.28M

Ownership

Promoter Holding
2.22%
Chg in Prom Hold
-
FII / Inst Holding
101.90%
Chg in FII Hold
0.11%

Financial Snapshot

Enterprise Value
$3.54B
Total Revenue (TTM)
$225.27M
EBITDA
$-180.68M
Free Cash Flow
$-57.25M
Operating Cash Flow
$-85.93M
Shares Outstanding
96.27M
Gross Margin
-50.73%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 IDYA IDEAYA Biosciences, Inc. R2K 36.74 -23.40 $3.54B 0.00% -15.17% -14.28% 62.11% -
2 LLY Eli Lilly and Company SPX 1,156.63 41.13 $1.03T 0.60% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 247.02 28.66 $594.63B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.11 119.08 $431.29B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 418.52 31.54 $380.08B 2.18% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 123.61 34.82 $305.29B 2.82% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 168.37 26.10 $261.12B 1.87% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 535.29 29.40 $198.93B 0.35% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 358.32 24.92 $193.39B 2.80% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue ----------8.97M7.25M8.76M8.98M11.36M5.85M29.70M7.88M3.54M8.04M000--207.83M-6.56M
Operating Income --7.57M-13.63M--10.09M-11.23M-11.62M--12.48M-12.59M-5.00M-9.13M-11.05M-11.71M-14.22M-22.50M660.00K-26.28M-32.71M-33.53M-51.02M-64.93M-66.89M-84.39M-88.81M108.45M--108.54M
Net Income -5.74M-7.00M-13.05M-8.56M-9.57M-10.66M-10.97M-10.78M-12.04M-12.39M-4.93M-9.02M-10.95M-11.58M-14.01M-22.06M1.61M-23.64M-27.93M-27.44M-39.57M-52.77M-51.82M-72.18M-77.49M119.24M--98.54M
Diluted EPS -------------0.33-0.31-0.36-0.570.04-0.49-0.50-0.46-0.53-0.68-0.60-0.82-0.881.33--1.11
R&D Expense -6.43M12.54M-8.00M8.86M8.92M-9.03M8.60M10.03M11.57M14.98M15.50M19.66M22.80M22.37M27.86M29.18M33.70M42.80M54.53M57.15M70.89M74.23M82.99M86.60M95.73M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue --019.54M27.94M50.93M23.39M7.00M218.71M
Operating Income -14.44M-36.42M-44.27M-35.34M-50.27M-62.50M-134.43M-326.98M-159.31M
Net Income -11.86M-34.35M-41.98M-34.49M-49.76M-58.66M-112.96M-274.48M-113.70M
Diluted EPS ----1.40-1.41-1.42-1.96-3.36-1.28
R&D Expense 12.38M31.75M34.32M39.70M58.16M89.54M129.51M294.67M314.70M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --96.54M113.00M298.27M381.35M387.97M649.32M1.12B1.11B
Total Equity -4.13M-15.74M-48.95M100.40M198.27M301.51M349.45M621.09M1.06B1.02B
Cash & Equivalents -5.96M20.50M34.07M72.04M92.05M68.63M157.02M84.38M112.83M
Total Liabilities --7.10M12.60M100.00M79.83M38.51M28.23M64.94M86.39M
Current Liabilities --5.41M6.94M38.64M45.16M31.72M27.10M46.07M58.81M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -12.22M-27.62M-39.31M55.46M-55.78M-87.17M-115.22M-247.58M-71.10M
Investing Cash Flow -8.93M-63.18M2.27M-146.24M-69.67M-33.40M-158.46M-502.56M69.98M
Financing Cash Flow 17.49M105.38M50.61M128.75M145.45M97.17M362.72M677.55M29.78M
Capital Expenditure -1.76M-1.71M-1.35M-493.00K-2.64M-3.44M-2.37M-3.86M-2.37M
Free Cash Flow -13.98M-29.33M-40.67M54.97M-58.42M-90.62M-117.59M-251.44M-73.47M

Ratios (Annual)

Figures in %.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------
Operating Margin % ----180.9%-179.9%-122.7%-574.9%-4,671.1%-72.8%
Net Margin % ----176.6%-178.1%-115.2%-483.0%-3,921.1%-52.0%
ROE % 75.4%70.2%-41.8%-17.4%-16.5%-16.8%-18.2%-25.9%-11.1%
ROCE % --40.0%-41.7%-13.6%-15.0%-17.5%-21.6%-30.3%-15.2%

Shareholding Pattern

Insiders
2.22%
Institutions
101.90%
Public Float
104.22%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 14.99% 13.17M $481.51M
2 Blackrock Inc. 9.61% 8.44M $308.60M
3 Janus Henderson Group PLC 8.27% 7.27M $265.58M
4 Capital Research Global Investors 5.88% 5.16M $188.75M
5 Baker Bros. Advisors, LP 4.49% 3.95M $144.26M
6 State Street Corporation 4.30% 3.78M $138.22M
7 Vanguard Capital Management LLC 4.25% 3.73M $136.44M
8 Logos Global Management LP 3.93% 3.45M $126.11M
9 Federated Hermes, Inc. 3.40% 2.99M $109.19M
10 Adage Capital Partners GP L.L.C. 3.21% 2.82M $103.21M

Analyst View

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Latest News

Recent headlines for IDYA

Google News Mon, 08 Jun 2026

IDEAYA Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants - PR Newswire

<a href="https://news.google.com/rss/articles/CBMi0wFBVV95cUxONFZKZG5hRFNHSWM0M1E0YjJ1R0hrUXVIUFVLU1NPLU1sT29tdkZvVDVGdmZjak51b0RYc1hITW56RjdWcEhQYi1nbU9sbU52bXdQWDNOQnc3RkxFRXNHbkZLNkNzODEwNWNQTm4ycmY3QlF6allmMkJNdnNIRFczdU5WTWZrTzBDSTRpam…

Google News hu, 09 Jul 2026

Insider Sale: Chief Accounting Officer of $IDYA Sells 9,550 Shares - Quiver Quantitative

<a href="https://news.google.com/rss/articles/CBMiqAFBVV95cUxNRFBmSVRxdE43VmgxZGI4TmZkZ3BkM3MxOGFxczJmX0Naay02Uk1LVzBkTmt1THFXcU9xeDdlLVA2Tk1NenRWcUVmOFd0UWpWejJQXzdpQW5LZnlWTDkyVHA2dkJCRUp0WmRmbG1RV1RQOXdnd1E2X3FKd1d0LVpNbjBDMUFGVktadFNINV…

Google News Sun, 03 May 2026

Is IDEAYA Biosciences, Inc. (IDYA) A Good Stock To Buy Now? - Yahoo Finance

<a href="https://news.google.com/rss/articles/CBMingFBVV95cUxQdEhSYV9uUndPVmx1UVVaZ2k2b3ZrU28xemhMMXVyRDZZWlZ0U0IteGFEUElEazE0NXJPVDVJZlBHc01EdjZRS09zVjFXWnd3eGpGZk90ZXhGN2E3R0Jub01mSUtjT1N4cG00eUthYWtCYU1UMGRWVW9vLW56YnM4VW9Va2d2ZVNwZi1mdk…

Google News hu, 09 Jul 2026

Insider Sale: Chief Accounting Officer of $IDYA Sells 9,550 Shares - Moomoo

<a href="https://news.google.com/rss/articles/CBMiqAFBVV95cUxOZU9DbmdFUVZWbEF0VWRWbTJfUlJjWmh3NEJhaWo0dUNJRHM3SUlNRjdQZlQweWktNUV1MVdFYkUwcUNjYzE4LW5LWlEweFEtWkNNN01lcGdSaE40Q2wtZWtVbEhzYnYtakgycUQyb3Y1ZzcxM0FUU00wa0R0WnFaOWxRYzNJYW5sYlo4eE…

Google News hu, 09 Jul 2026

IDEAYA Biosciences (IDYA) CAO exercises options, sells 9,550 pre-planned shares - Stock Titan

<a href="https://news.google.com/rss/articles/CBMitwFBVV95cUxObElSNFpVSHFoUVpaSE5udVpLcUZEMmg3cVJXMFlqOGFxTEhvdThoa2lXdnZ6SG5TYVdFOW03WGRBVnNma2M5eVYwMGwtQXhaWXY0NXFRZko5dmhvem1DMFJEOVJLa0xwSmhiRnIxQ3k2QkFyY0VwTkd2ZG94dWI3bHF6UVA4WVNXeTNCT2…

Google News Sun, 12 Jul 2026

Nasdaq, S&P 500 Futures Slip As Hormuz Blockade Escalates Tensions: Why BATL, INTC, PLTR, IDYA Are On Traders' Radar Today - Stocktwits

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IDYA — Frequently Asked Questions

What is the current share price of IDEAYA Biosciences, Inc. (IDYA)?

As of 2026-07-15 16:51 PDT, IDEAYA Biosciences, Inc. (IDYA) trades at $36.74 on NasdaqGS. Its 52-week range is $21.43 to $40.51.

What is the market capitalisation of IDYA?

IDEAYA Biosciences, Inc. (IDYA) has a market capitalisation of $3.54B on NasdaqGS.

What is the P/E ratio of IDYA?

IDYA trades at a trailing price-to-earnings (P/E) ratio of -23.40. The industry average P/E is 25.88. Its price-to-book (P/B) ratio is 3.43.

What is the return on equity (ROE) of IDYA?

IDYA has a return on equity (ROE) of -14.28%. Its return on capital employed (ROCE) is -15.17%.

Is IDYA a good stock to buy?

This page provides a data-driven analysis of IDEAYA Biosciences, Inc. (IDYA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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