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Guardant Health, Inc. GH R2K

Healthcare · Diagnostics & Research · United States
https://guardanthealth.com

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. It has a strategic collaboration with Nuvalent, Inc. for oncology drug development. The company was incorporated in 2011 and is headquartered in Palo Alto, California.

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$129.69
+219.28% 1Y

Market & Price

Market Cap
$17.20B
Current Price
$129.69
High / Low (52W)
$133.22 / $40.62
Beta
1.49

Valuation

Stock P/E
-
Industry PE
23.65
Forward P/E
-
PEG Ratio
-
Book Value
$-1.38
Price to Book
-94.18
P/S
15.92
EV/EBITDA
-43.61
Dividend Yield
-

Profitability & Returns

ROCE
-24.18%
ROE
-
ROA
-17.15%
Profit Margin
-40.10%
Op Margin
-40.23%
EPS (Latest Qtr)
$-0.85
EPS (TTM)
$-3.40

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
4.25
Current Ratio
4.68
Debt
$1.70B
Total Assets
$2.01B
Current Assets
$1.47B
Working Capital
$1.16B

Ownership

Promoter Holding
4.03%
Chg in Prom Hold
-0.01%
FII / Inst Holding
105.77%
Chg in FII Hold
0.02%

Financial Snapshot

Enterprise Value
$17.80B
Total Revenue (TTM)
$1.08B
EBITDA
$-408.16M
Free Cash Flow
$-85.45M
Operating Cash Flow
$-187.69M
Shares Outstanding
132.60M
Gross Margin
64.90%
Payout Ratio
0.00%

Growth (CAGR)

Revenue 5Y
29.75%
Profit 5Y
12.14%
Revenue (YoY)
48.30%
Earnings (YoY)
-

PROS

  • Compounding revenue at 29.8% over 5 years.
  • Profit CAGR of 12.1% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • RSI at 78 suggests overbought conditions.

* The pros and cons are auto-generated from financial metrics.

Price Chart

Robinhood TradingView StockAnalysis

Fundamental Growth

Figures from the latest reported periods. CAGR is computed across the displayed window (quarterly CAGR is annualised assuming 4 quarters per year).

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 GH Guardant Health, Inc. R2K 129.69 - $17.20B - -24.18% - 29.75% 12.14%
2 LLY Eli Lilly and Company SPX 1,105.00 39.21 $985.37B 0.63% 38.44% 107.46% 31.69% 48.96%
3 JNJ Johnson & Johnson SPX 225.33 26.11 $542.42B 2.38% 23.13% 26.42% 5.60% 14.32%
4 UNH UnitedHealth Group Incorporated SPX 380.31 28.66 $345.38B 2.32% 9.60% 12.18% 11.35% -15.69%
5 MRK Merck & Co., Inc. SPX 118.72 33.44 $293.22B 2.86% 20.66% 18.94% 3.12% 7.93%
6 TMO Thermo Fisher Scientific Inc. SPX 492.51 27.11 $183.03B 0.38% 9.17% 13.52% -0.27% -1.19%
7 AMGN Amgen Inc. NDXSPX 336.79 23.42 $181.77B 2.99% 18.02% 101.32% 11.77% 5.58%
8 GILD Gilead Sciences, Inc. NDXSPX 134.43 18.29 $166.90B 2.44% 22.92% 43.36% 2.57% 22.83%
9 ISRG Intuitive Surgical, Inc. NDXSPXAI 424.64 51.53 $150.39B - 15.96% 17.23% 17.39% 29.26%
Ad space

Quarterly Results

Figures in USD.

Metric Sep 2017Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue -------------------168.49M177.24M191.48M203.47M232.09M265.20M281.27M301.67M
Cost of Revenue ----------------------74.72M81.20M93.59M99.49M104.92M
Gross Profit ----------------------128.75M150.88M171.61M181.77M196.75M
Operating Expenses ----------------------239.79M257.30M270.60M302.58M318.10M
Operating Income -28.68M-18.65M-22.70M-24.20M-23.66M-15.27M-17.48M-34.91M-54.62M-74.25M-107.86M-97.64M-107.29M-123.34M-130.32M-144.60M-134.06M-119.62M-113.54M-99.68M-100.62M-117.33M-111.04M-106.41M-98.99M-120.81M-121.35M
EBITDA -----------------------83.84M-88.84M-82.24M-118.99M-100.91M
Interest Expense ----------------------791.00K983.00K943.00K1.18M1.35M
Pretax Income -----------------------94.87M-99.86M-92.59M-130.22M-111.70M
Tax Provision ----------------------290.00K38.00K136.00K-1.73M372.00K
Net Income -28.59M---24.46M----------123.23M-229.43M-161.99M-133.53M-72.77M-86.10M-114.98M-102.63M-107.75M-95.16M-99.90M-92.72M-128.49M-112.08M
Diluted EPS ---------0.57-0.78-1.09-0.96-1.06-1.21-2.25-1.58-1.30-0.67-0.73-0.94-0.84-0.88-0.77-0.80-0.74-1.00-0.85
R&D Expense 7.25M8.26M11.55M14.25M16.32M19.53M24.57M37.02M36.32M36.24M55.51M63.72M70.97M81.76M85.45M100.02M93.13M90.36M93.85M83.80M83.10M87.31M88.52M87.45M89.96M-91.04M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue ------449.54M563.95M739.02M982.02M
Cost of Revenue ------156.32M227.05M289.80M349.01M
Gross Profit ------293.21M336.90M449.22M633.01M
Operating Expenses ------837.59M901.62M892.81M1.07B
Operating Income -43.85M-76.61M-92.94M-82.37M-254.95M--544.38M-564.73M-443.59M-437.25M
EBITDA -------614.91M-433.31M-390.12M-373.91M
Interest Expense ------2.58M2.58M2.58M3.90M
Pretax Income -------653.45M-478.76M-435.09M-417.54M
Tax Provision ------1.14M685.00K1.28M-1.26M
Net Income -46.14M-83.22M-85.06M-75.65M---654.59M-479.45M-436.37M-416.28M
Diluted EPS ----0.84-2.60--6.41-4.28-3.56-3.32
R&D Expense 10.86M25.56M50.71M86.29M149.86M263.22M373.81M367.19M347.75M364.19M

Compounded Sales Growth

5 Years:29.75%
1 Year:48.30%

Compounded Profit Growth

5 Years:12.14%
1 Year:-

Stock Price Performance

1 Year:+219.28%
6 Months:+19.19%
3 Months:+38.12%
1 Month:+55.48%

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --342.94M587.40M962.53M2.27B-1.61B1.79B1.49B2.01B
Current Assets -------1.19B1.35B1.06B1.47B
Cash & Equivalents --72.28M140.54M143.23M832.98M-141.65M1.13B525.54M378.20M
Inventory -------51.60M61.95M71.08M85.88M
Receivables -------97.26M83.88M106.85M132.65M
Total Liabilities --34.33M62.45M114.54M916.19M-1.55B1.63B1.63B2.11B
Current Liabilities --19.63M46.94M72.73M66.81M-193.22M205.92M225.58M302.73M
Long Term Debt -------1.14B1.14B1.14B1.50B
Total Debt -------1.37B1.35B1.34B1.71B
Total Equity 83.44M79.70M308.61M483.15M798.39M1.30B-60.18M158.68M-139.65M-99.31M
Shares Outstanding -------102.62M121.63M123.99M130.64M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -36.71M-72.23M-72.19M-47.13M-103.93M--309.46M-324.98M-239.86M-184.76M
Investing Cash Flow 26.20M-170.42M-153.03M-317.57M-617.09M-149.82M840.25M-261.31M-627.20M
Financing Cash Flow 39.84M281.66M293.16M367.30M1.41B--189.09M477.38M-996.00K671.13M
Capital Expenditure -1.77M-6.68M-20.20M-18.72M-36.17M--77.46M-20.49M-35.09M-48.31M
Free Cash Flow -38.48M-78.92M-92.39M-65.85M-140.10M--386.92M-345.46M-274.94M-233.07M
Net Change in Cash -------348.74M992.65M-502.16M-140.83M
Share Buybacks 100.00K7.22M172.00K00--0045.01M

Ratios (Annual)

Figures in %.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ------65.2%59.7%60.8%64.5%
Operating Margin % -------121.1%-100.1%-60.0%-44.5%
Net Margin % -------145.6%-85.0%-59.0%-42.4%
ROE % -57.9%-27.0%-17.6%-9.5%---1,087.7%-302.1%312.5%419.2%
ROCE % --23.7%-17.2%-9.3%-11.6%--38.4%-35.7%-35.2%-25.6%

Shareholding Pattern

Insiders
4.03%
Institutions
105.77%
Public Float
110.22%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 8.71% 11.55M $1.50B
2 Price (T.Rowe) Associates Inc 5.30% 7.02M $910.90M
3 Vanguard Portfolio Management LLC 4.40% 5.84M $757.13M
4 Vanguard Capital Management LLC 4.24% 5.62M $729.40M
5 Invesco Ltd. 3.73% 4.95M $641.51M
6 Goldman Sachs Group Inc 3.35% 4.44M $575.28M
7 Two Sigma Investments, LP 3.19% 4.23M $548.53M
8 FMR, LLC 3.10% 4.12M $533.81M
9 BAILLIE GIFFORD & CO 2.91% 3.86M $500.48M
10 Geode Capital Management, LLC 2.65% 3.51M $455.07M

Analyst View

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