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Guardant Health, Inc. GH R2KR3KPHARMA

Healthcare · Diagnostics & Research · United States
https://guardanthealth.com
Company Profile ↓
$161.41
+175.58% 1Y
Mkt Cap$21.66B
P/E-45.99
P/B-101.01
52W High$170.92
52W Low$54.79
Book Value$-1.67
EPS (TTM)$-3.51

Company Overview

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. It has a strategic collaboration with Nuvalent, Inc. for oncology drug development. The company was incorporated in 2011 and is headquartered in Palo Alto, California.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 50.2% CAGR over the past five years.

Positive Free Cash Flow

Generates positive free cash flow, funding growth and shareholder returns internally.

Recent Developments

  • Dec 2025 Revenue of $982.02M (+32.9% YoY); net profit $-416.28M.
  • Trailing 12 Months Year-on-year growth — revenue +44.3%.
  • 5-Year Trend Long-term compounding — revenue CAGR 50.2%.

Growth & Price Performance

Compounded Sales Growth

5 Years:50.19%
1 Year:44.30%

Stock Price Performance

1 Year:+175.58%
6 Months:+76.98%
3 Months:+28.50%
1 Month:+2.43%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 92% of range
$54.79 $170.92
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)50.21 · Neutral
Price Performance
1M+2.43%
3M+28.50%
6M+76.98%
1Y+175.58%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 50.2% over 5 years.
  • Generates positive free cash flow.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-45.99
Industry PE
25.17
Forward P/E
-358.59
PEG Ratio
-
Book Value
$-1.67
Price to Book
-101.01
P/S
19.11
EV/EBITDA
-54.01
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
50.19%
Profit 5Y
-
Revenue (YoY)
44.30%
Earnings (YoY)
-

Profitability & Returns

ROCE
-25.56%
ROE
-
ROA
-18.07%
Profit Margin
-38.33%
Op Margin
-38.25%
Gross Margin
65.01%
EPS (Latest Qtr)
$-0.90
EPS (TTM)
$-3.51

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
3.53
Current Ratio
4.03
Debt
$1.70B
Total Assets
$1.91B
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
3.97%
Chg in Prom Hold
0.00%
FII / Inst Holding
100.95%
Chg in FII Hold
0.04%

Financial Snapshot

Enterprise Value
$21.66B
Total Revenue (TTM)
$1.18B
EBITDA
$-430.57M
Free Cash Flow
$26.61M
Operating Cash Flow
$-185.19M
Shares Outstanding
134.20M
Gross Margin
65.01%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 GH Guardant Health, Inc. R2KR3KPHARMA 161.41 -45.99 $21.66B 0.00% -25.56% - 50.19% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Sep 2017Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue -------------------168.49M177.24M191.48M203.47M232.09M265.20M301.67M334.98M
Operating Income -28.68M-18.65M-22.70M-24.20M-23.66M-15.27M-17.48M-34.91M-54.62M-74.25M-107.86M-97.64M-107.29M-123.34M-130.32M-144.60M-134.06M-119.62M-113.54M-99.68M-100.62M-117.33M-111.04M-106.41M-98.99M-121.35M-129.12M
Net Income -28.59M---24.46M----------123.23M-229.43M-161.99M-133.53M-72.77M-86.10M-114.98M-102.63M-107.75M-95.16M-99.90M-92.72M-112.08M-120.14M
Diluted EPS ---------0.57-0.78-1.09-0.96-1.06-1.21-2.25-1.58-1.30-0.67-0.73-0.94-0.84-0.88-0.77-0.80-0.74-0.85-0.90
R&D Expense 7.25M8.26M11.55M14.25M16.32M19.53M24.57M37.02M36.32M36.24M55.51M63.72M70.97M81.76M85.45M100.02M93.13M90.36M93.85M83.80M83.10M87.31M88.52M87.45M89.96M91.04M96.53M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 25.25M49.84M90.64M214.38M286.73M373.65M449.54M563.95M739.02M982.02M
Operating Income -43.85M-76.61M-92.94M-82.37M-254.95M-411.00M-544.38M-564.73M-443.59M-437.25M
Net Income -46.14M-83.22M-85.06M-75.65M-253.78M-384.77M-654.59M-479.45M-436.37M-416.28M
Diluted EPS ----0.84-2.60-4.00-6.41-4.28-3.56-3.32
R&D Expense 10.86M25.56M50.71M86.29M149.86M263.22M373.81M367.19M347.75M364.19M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --342.94M587.40M962.53M2.27B2.20B1.61B1.79B1.49B2.01B
Total Equity 83.44M79.70M308.61M483.15M798.39M1.30B645.00M60.18M158.68M-139.65M-99.31M
Cash & Equivalents --72.28M140.54M143.23M832.98M492.20M141.65M1.13B525.54M378.20M
Long Term Debt ---------1.14B1.50B
Total Liabilities --34.33M62.45M114.54M916.19M1.56B1.55B1.63B1.63B2.11B
Current Liabilities --19.63M46.94M72.73M66.81M194.69M193.22M205.92M225.58M302.73M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -36.71M-72.23M-72.19M-47.13M-103.93M-209.02M-309.46M-324.98M-239.86M-184.76M
Investing Cash Flow 26.20M-170.42M-153.03M-317.57M-617.09M-63.16M149.82M840.25M-261.31M-627.20M
Financing Cash Flow 39.84M281.66M293.16M367.30M1.41B-66.82M-189.09M477.38M-996.00K671.13M
Capital Expenditure -1.77M-6.68M-20.20M-18.72M-36.17M-75.03M-77.46M-20.49M-35.09M-48.31M
Free Cash Flow -38.48M-78.92M-92.39M-65.85M-140.10M-284.05M-386.92M-345.46M-274.94M-233.07M
Share Buybacks 100.00K7.22M172.00K00--0045.01M

Ratios (Annual)

Figures in %.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ----------
Operating Margin % -173.7%-153.7%-102.5%-38.4%-88.9%-110.0%-121.1%-100.1%-60.0%-44.5%
Net Margin % -182.7%-167.0%-93.8%-35.3%-88.5%-103.0%-145.6%-85.0%-59.0%-42.4%
ROE % -57.9%-27.0%-17.6%-9.5%-19.5%-59.7%-1,087.7%-302.1%312.5%419.2%
ROCE % --23.7%-17.2%-9.3%-11.6%-20.4%-38.4%-35.7%-35.2%-25.6%

Shareholding Pattern

Insiders
3.97%
Institutions
100.95%
Public Float
105.13%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 5.68% 7.62M $1.23B
2 Price (T.Rowe) Associates Inc 4.85% 6.51M $1.05B
3 Vanguard Capital Management LLC 4.29% 5.76M $929.57M
4 FMR, LLC 4.09% 5.49M $886.36M
5 Vanguard Portfolio Management LLC 4.06% 5.45M $879.49M
6 Invesco Ltd. 3.30% 4.43M $715.41M
7 Goldman Sachs Group Inc 2.81% 3.78M $609.81M
8 Two Sigma Investments, LP 2.77% 3.72M $600.67M
9 Capital International Investors 2.53% 3.40M $549.04M
10 Deep Track Capital, Lp 2.53% 3.39M $548.02M

Analyst View

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Latest News

Recent headlines for GH

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Google News Sat, 05 Sep 2026

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Google News ue, 30 Jun 2026

Guardant Health Stock Surges 19%, With A 5-Day Winning Spree - Trefis

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Google News Sat, 25 Jul 2026

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GH — Frequently Asked Questions

What is the current share price of Guardant Health, Inc. (GH)?

As of 2026-09-07 16:24 PDT, Guardant Health, Inc. (GH) trades at $161.41 on NasdaqGS. Its 52-week range is $54.79 to $170.92.

What is the market capitalisation of GH?

Guardant Health, Inc. (GH) has a market capitalisation of $21.66B on NasdaqGS.

What is the P/E ratio of GH?

GH trades at a trailing price-to-earnings (P/E) ratio of -45.99. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is -101.01.

Is GH a good stock to buy?

This page provides a data-driven analysis of Guardant Health, Inc. (GH), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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