Guardant Health, Inc. GH R2K
Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; and Guardant360 Tissue test, a molecular profiling test for tumor tissue that provides genomic, transcriptomic, and epigenomic insights. It also provides Shield blood test for colorectal cancer screening in adults. In addition, the company offers GuardantINFINITY test that provides insights into the complexities of tumor molecular profiles and immune response to advance cancer research and therapy development; GuardantOMNI test covers 500 genes, including genes associated with homologous recombination repair deficiency and biomarkers for immuno-oncology applications; GuardantINFORM, which provides longitudinal biological insight into tumor evolution alongside longitudinal clinical outcomes; and GuardantConnect, an integrated software-based solution designed for clinical and biopharmaceutical customers to connect patients tested with assays with actionable alterations with potentially relevant clinical studies. Further, it provides Smart Platform, which delivers multiomic insights leveraging genomic, epigenomic, and RNA-based data that are scalable from research to the clinic. Additionally, the company offers development services, including companion diagnostic development and regulatory approval, clinical study setup, monitoring and maintenance, testing development and support, technologies licensing, and kit fulfillment and delivery of Shield screening tests. It has a strategic collaboration with Nuvalent, Inc. for oncology drug development. The company was incorporated in 2011 and is headquartered in Palo Alto, California.
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Valuation
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Growth (CAGR)
PROS
- Compounding revenue at 29.8% over 5 years.
- Profit CAGR of 12.1% over 5 years.
- In a confirmed uptrend (50-DMA above 200-DMA).
CONS
- RSI at 78 suggests overbought conditions.
* The pros and cons are auto-generated from financial metrics.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth
No fundamental data available for this stock.
Figures from the latest reported periods. CAGR is computed across the displayed window (quarterly CAGR is annualised assuming 4 quarters per year).
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | GH Guardant Health, Inc. R2K | 129.69 | - | $17.20B | - | -24.18% | - | 29.75% | 12.14% |
| 2 | LLY Eli Lilly and Company SPX | 1,105.00 | 39.21 | $985.37B | 0.63% | 38.44% | 107.46% | 31.69% | 48.96% |
| 3 | JNJ Johnson & Johnson SPX | 225.33 | 26.11 | $542.42B | 2.38% | 23.13% | 26.42% | 5.60% | 14.32% |
| 4 | UNH UnitedHealth Group Incorporated SPX | 380.31 | 28.66 | $345.38B | 2.32% | 9.60% | 12.18% | 11.35% | -15.69% |
| 5 | MRK Merck & Co., Inc. SPX | 118.72 | 33.44 | $293.22B | 2.86% | 20.66% | 18.94% | 3.12% | 7.93% |
| 6 | TMO Thermo Fisher Scientific Inc. SPX | 492.51 | 27.11 | $183.03B | 0.38% | 9.17% | 13.52% | -0.27% | -1.19% |
| 7 | AMGN Amgen Inc. NDXSPX | 336.79 | 23.42 | $181.77B | 2.99% | 18.02% | 101.32% | 11.77% | 5.58% |
| 8 | GILD Gilead Sciences, Inc. NDXSPX | 134.43 | 18.29 | $166.90B | 2.44% | 22.92% | 43.36% | 2.57% | 22.83% |
| 9 | ISRG Intuitive Surgical, Inc. NDXSPXAI | 424.64 | 51.53 | $150.39B | - | 15.96% | 17.23% | 17.39% | 29.26% |
Quarterly Results
Figures in USD.
| Metric | Sep 2017 | Mar 2018 | Jun 2018 | Sep 2018 | Mar 2019 | Jun 2019 | Sep 2019 | Mar 2020 | Jun 2020 | Sep 2020 | Mar 2021 | Jun 2021 | Sep 2021 | Mar 2022 | Jun 2022 | Sep 2022 | Mar 2023 | Jun 2023 | Sep 2023 | Mar 2024 | Jun 2024 | Sep 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 168.49M | 177.24M | 191.48M | 203.47M | 232.09M | 265.20M | 281.27M | 301.67M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 74.72M | 81.20M | 93.59M | 99.49M | 104.92M |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 128.75M | 150.88M | 171.61M | 181.77M | 196.75M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 239.79M | 257.30M | 270.60M | 302.58M | 318.10M |
| Operating Income | -28.68M | -18.65M | -22.70M | -24.20M | -23.66M | -15.27M | -17.48M | -34.91M | -54.62M | -74.25M | -107.86M | -97.64M | -107.29M | -123.34M | -130.32M | -144.60M | -134.06M | -119.62M | -113.54M | -99.68M | -100.62M | -117.33M | -111.04M | -106.41M | -98.99M | -120.81M | -121.35M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -83.84M | -88.84M | -82.24M | -118.99M | -100.91M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 791.00K | 983.00K | 943.00K | 1.18M | 1.35M |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -94.87M | -99.86M | -92.59M | -130.22M | -111.70M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 290.00K | 38.00K | 136.00K | -1.73M | 372.00K |
| Net Income | -28.59M | - | - | -24.46M | - | - | - | - | - | - | - | - | - | -123.23M | -229.43M | -161.99M | -133.53M | -72.77M | -86.10M | -114.98M | -102.63M | -107.75M | -95.16M | -99.90M | -92.72M | -128.49M | -112.08M |
| Diluted EPS | - | - | - | - | - | - | - | - | -0.57 | -0.78 | -1.09 | -0.96 | -1.06 | -1.21 | -2.25 | -1.58 | -1.30 | -0.67 | -0.73 | -0.94 | -0.84 | -0.88 | -0.77 | -0.80 | -0.74 | -1.00 | -0.85 |
| R&D Expense | 7.25M | 8.26M | 11.55M | 14.25M | 16.32M | 19.53M | 24.57M | 37.02M | 36.32M | 36.24M | 55.51M | 63.72M | 70.97M | 81.76M | 85.45M | 100.02M | 93.13M | 90.36M | 93.85M | 83.80M | 83.10M | 87.31M | 88.52M | 87.45M | 89.96M | - | 91.04M |
Profit & Loss (Annual)
Figures in USD.
| Metric | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | 449.54M | 563.95M | 739.02M | 982.02M |
| Cost of Revenue | - | - | - | - | - | - | 156.32M | 227.05M | 289.80M | 349.01M |
| Gross Profit | - | - | - | - | - | - | 293.21M | 336.90M | 449.22M | 633.01M |
| Operating Expenses | - | - | - | - | - | - | 837.59M | 901.62M | 892.81M | 1.07B |
| Operating Income | -43.85M | -76.61M | -92.94M | -82.37M | -254.95M | - | -544.38M | -564.73M | -443.59M | -437.25M |
| EBITDA | - | - | - | - | - | - | -614.91M | -433.31M | -390.12M | -373.91M |
| Interest Expense | - | - | - | - | - | - | 2.58M | 2.58M | 2.58M | 3.90M |
| Pretax Income | - | - | - | - | - | - | -653.45M | -478.76M | -435.09M | -417.54M |
| Tax Provision | - | - | - | - | - | - | 1.14M | 685.00K | 1.28M | -1.26M |
| Net Income | -46.14M | -83.22M | -85.06M | -75.65M | - | - | -654.59M | -479.45M | -436.37M | -416.28M |
| Diluted EPS | - | - | - | -0.84 | -2.60 | - | -6.41 | -4.28 | -3.56 | -3.32 |
| R&D Expense | 10.86M | 25.56M | 50.71M | 86.29M | 149.86M | 263.22M | 373.81M | 367.19M | 347.75M | 364.19M |
Compounded Sales Growth
| 5 Years: | 29.75% |
| 1 Year: | 48.30% |
Compounded Profit Growth
| 5 Years: | 12.14% |
| 1 Year: | - |
Stock Price Performance
| 1 Year: | +219.28% |
| 6 Months: | +19.19% |
| 3 Months: | +38.12% |
| 1 Month: | +55.48% |
Balance Sheet (Annual)
Figures in USD.
| Metric | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | - | - | 342.94M | 587.40M | 962.53M | 2.27B | - | 1.61B | 1.79B | 1.49B | 2.01B |
| Current Assets | - | - | - | - | - | - | - | 1.19B | 1.35B | 1.06B | 1.47B |
| Cash & Equivalents | - | - | 72.28M | 140.54M | 143.23M | 832.98M | - | 141.65M | 1.13B | 525.54M | 378.20M |
| Inventory | - | - | - | - | - | - | - | 51.60M | 61.95M | 71.08M | 85.88M |
| Receivables | - | - | - | - | - | - | - | 97.26M | 83.88M | 106.85M | 132.65M |
| Total Liabilities | - | - | 34.33M | 62.45M | 114.54M | 916.19M | - | 1.55B | 1.63B | 1.63B | 2.11B |
| Current Liabilities | - | - | 19.63M | 46.94M | 72.73M | 66.81M | - | 193.22M | 205.92M | 225.58M | 302.73M |
| Long Term Debt | - | - | - | - | - | - | - | 1.14B | 1.14B | 1.14B | 1.50B |
| Total Debt | - | - | - | - | - | - | - | 1.37B | 1.35B | 1.34B | 1.71B |
| Total Equity | 83.44M | 79.70M | 308.61M | 483.15M | 798.39M | 1.30B | - | 60.18M | 158.68M | -139.65M | -99.31M |
| Shares Outstanding | - | - | - | - | - | - | - | 102.62M | 121.63M | 123.99M | 130.64M |
Cash Flows (Annual)
Figures in USD.
| Metric | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -36.71M | -72.23M | -72.19M | -47.13M | -103.93M | - | -309.46M | -324.98M | -239.86M | -184.76M |
| Investing Cash Flow | 26.20M | -170.42M | -153.03M | -317.57M | -617.09M | - | 149.82M | 840.25M | -261.31M | -627.20M |
| Financing Cash Flow | 39.84M | 281.66M | 293.16M | 367.30M | 1.41B | - | -189.09M | 477.38M | -996.00K | 671.13M |
| Capital Expenditure | -1.77M | -6.68M | -20.20M | -18.72M | -36.17M | - | -77.46M | -20.49M | -35.09M | -48.31M |
| Free Cash Flow | -38.48M | -78.92M | -92.39M | -65.85M | -140.10M | - | -386.92M | -345.46M | -274.94M | -233.07M |
| Net Change in Cash | - | - | - | - | - | - | -348.74M | 992.65M | -502.16M | -140.83M |
| Share Buybacks | 100.00K | 7.22M | 172.00K | 0 | 0 | - | - | 0 | 0 | 45.01M |
Ratios (Annual)
Figures in %.
| Metric | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | 65.2% | 59.7% | 60.8% | 64.5% |
| Operating Margin % | - | - | - | - | - | - | -121.1% | -100.1% | -60.0% | -44.5% |
| Net Margin % | - | - | - | - | - | - | -145.6% | -85.0% | -59.0% | -42.4% |
| ROE % | -57.9% | -27.0% | -17.6% | -9.5% | - | - | -1,087.7% | -302.1% | 312.5% | 419.2% |
| ROCE % | - | -23.7% | -17.2% | -9.3% | -11.6% | - | -38.4% | -35.7% | -35.2% | -25.6% |
Shareholding Pattern
Top Institutional Holders
| # | Holder | % Held | Shares | Value |
|---|---|---|---|---|
| 1 | Blackrock Inc. | 8.71% | 11.55M | $1.50B |
| 2 | Price (T.Rowe) Associates Inc | 5.30% | 7.02M | $910.90M |
| 3 | Vanguard Portfolio Management LLC | 4.40% | 5.84M | $757.13M |
| 4 | Vanguard Capital Management LLC | 4.24% | 5.62M | $729.40M |
| 5 | Invesco Ltd. | 3.73% | 4.95M | $641.51M |
| 6 | Goldman Sachs Group Inc | 3.35% | 4.44M | $575.28M |
| 7 | Two Sigma Investments, LP | 3.19% | 4.23M | $548.53M |
| 8 | FMR, LLC | 3.10% | 4.12M | $533.81M |
| 9 | BAILLIE GIFFORD & CO | 2.91% | 3.86M | $500.48M |
| 10 | Geode Capital Management, LLC | 2.65% | 3.51M | $455.07M |
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
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