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4D Molecular Therapeutics, Inc. FDMT R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://www.4dmoleculartherapeutics.com
Company Profile ↓
$10.80
+61.92% 1Y
Mkt Cap$596.64M
P/E-4.11
P/B1.81
52W High$16.76
52W Low$6.14
Book Value$7.38
EPS (TTM)$-2.63

Company Overview

4D Molecular Therapeutics, Inc., a late-stage biotechnology company, engages in the development of adeno-associated virus vectors from its proprietary synthetic vector discovery platform, Therapeutic Vector Evolution in the Netherlands and the United States. The company's lead product candidate is 4D-150 for the treatment of retinal vascular diseases by providing multi-year sustained production of anti-VEGF from the retina with intravitreal injection, as well as for treating wet age-related macular degeneration and diabetic macular edema. It is also developing 4D-710, which is in early-stage study for the treatment of cystic fibrosis; 4D-175 that is in preclinical stage for treating geographic atrophy; and 4D-725, which is in preclinical stage for the treatment of alpha-1 anti-trypsin deficiency lung disease. 4D Molecular Therapeutics, Inc. has collaboration and licensing agreements with Otsuka Pharmaceutical Co., Ltd. The company was founded in 2013 and is headquartered in EmeryVille, California.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 51.8% CAGR over the past five years.

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.10.

Recent Developments

  • Dec 2025 Revenue of $85.21M (+230194.6% YoY); net profit $-140.11M.
  • 5-Year Trend Long-term compounding — revenue CAGR 51.8%.

Growth & Price Performance

Compounded Sales Growth

5 Years:51.81%
1 Year:-

Stock Price Performance

1 Year:+61.92%
6 Months:+14.89%
3 Months:+4.05%
1 Month:-26.58%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Mixed
52-Week Range 44% of range
$6.14 $16.76
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMAAbove
  • RSI (14)33.15 · Neutral
Price Performance
1M-26.58%
3M+4.05%
6M+14.89%
1Y+61.92%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 51.8% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Trading 35.6% below its 52-week high.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-4.11
Industry PE
25.45
Forward P/E
-2.64
PEG Ratio
-
Book Value
$7.38
Price to Book
1.81
P/S
8.00
EV/EBITDA
-1.98
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
51.81%
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-30.52%
ROE
-43.25%
ROA
-25.09%
Profit Margin
-
Op Margin
-
Gross Margin
-
EPS (Latest Qtr)
$-1.01
EPS (TTM)
$-2.63

Balance Sheet & Liquidity

Debt/Equity
0.10
Quick Ratio
7.68
Current Ratio
8.03
Debt
$39.22M
Total Assets
$512.90M
Current Assets
$405.36M
Working Capital
$361.96M

Ownership

Promoter Holding
2.93%
Chg in Prom Hold
-0.03%
FII / Inst Holding
106.07%
Chg in FII Hold
0.17%

Financial Snapshot

Enterprise Value
$596.64M
Total Revenue (TTM)
$92.01M
EBITDA
$-188.89M
Free Cash Flow
$-90.77M
Operating Cash Flow
$-156.07M
Shares Outstanding
55.24M
Gross Margin
-
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 FDMT 4D Molecular Therapeutics, Inc. R2KR3KPHARMA 10.80 -4.11 $596.64M 0.00% -30.52% -43.25% 51.81% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,273.46 42.83 $1.14T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 263.81 30.60 $635.76B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 285.64 80.69 $504.76B 2.54% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 418.09 26.85 $375.28B 2.47% 9.74% 14.15% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPXR3KPHARMA 145.27 116.22 $358.41B 2.31% - 6.96% 5.64% 10.01%
7 NVS Novartis AG PHARMA 151.12 22.83 $287.24B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 171.49 25.63 $265.96B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 673.82 36.30 $249.14B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue 3.41M3.51M7.42M2.00M14.58M1.37M1.22M162.00K500.00K298.00K239.00K20.20M28.00K5.00K3.00K14.00K15.00K90.00K3.05M
Operating Income -13.28M-15.15M-7.82M-16.31M-7.60M-22.66M-26.39M-28.43M-26.50M-30.11M-32.14M-13.97M-38.14M-42.46M-51.13M-53.62M-59.46M-61.19M-73.62M
Net Income -13.16M-15.15M-7.83M-16.41M-7.59M-22.24M-26.34M-28.09M-25.69M-28.68M-29.62M-10.26M-32.40M-34.95M-43.84M-47.97M-54.66M-56.88M-68.76M
Diluted EPS -----0.28-0.82-0.82-0.87-0.79-0.88-0.77-0.24-0.66-0.63-0.79-0.86-0.98-1.01-1.01
R&D Expense 13.16M15.72M11.55M12.77M15.22M15.84M-------------

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 6.96M13.36M18.04M3.13M20.72M37.00K85.21M
Operating Income -50.76M-56.66M-71.33M-110.03M-112.87M-187.84M-159.55M
Net Income -49.31M-56.69M-71.32M-107.49M-100.84M-160.87M-140.11M
Diluted EPS ---2.57-3.32-2.58-2.98-2.42

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -58.23M288.33M353.49M261.85M339.89M560.38M566.71M
Total Equity -27.59M-72.97M256.39M319.11M231.34M307.83M510.61M505.66M
Cash & Equivalents -49.65M276.73M153.00M52.35M249.11M149.34M60.24M
Total Liabilities -28.22M31.94M34.38M30.51M32.06M49.78M61.05M
Current Liabilities -12.96M16.74M16.34M15.73M18.95M29.15M43.98M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -36.71M-50.91M-69.13M-86.69M-75.79M-134.59M-109.08M
Investing Cash Flow -3.20M-1.00M-172.68M-17.05M115.72M-302.44M-92.97M
Financing Cash Flow -2.19M278.98M118.09M3.08M156.83M337.25M112.96M
Capital Expenditure -3.20M-1.00M-9.11M-11.54M-2.77M-3.79M-536.00K
Free Cash Flow -39.91M-51.91M-78.24M-98.22M-78.56M-138.37M-109.62M

Ratios (Annual)

Figures in %.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -------
Operating Margin % -729.4%-424.0%-395.5%-3,516.5%-544.6%-507,678.4%-187.2%
Net Margin % -708.4%-424.3%-395.4%-3,435.4%-486.6%-434,778.4%-164.4%
ROE % 67.6%-22.1%-22.3%-46.5%-32.8%-31.5%-27.7%
ROCE % -112.1%-20.9%-21.2%-44.7%-35.2%-35.4%-30.5%

Shareholding Pattern

Insiders
2.93%
Institutions
106.07%
Public Float
109.28%

Top Institutional Holders

#Holder% HeldSharesValue
1 Jupiter Topco LLC 10.40% 5.75M $76.60M
2 RA Capital Management, L.P. 9.14% 5.05M $67.31M
3 Blackrock Inc. 8.23% 4.55M $60.60M
4 Goldman Sachs Group Inc 7.71% 4.26M $56.77M
5 Novo Holdings A/S 5.88% 3.25M $43.31M
6 State Street Corporation 5.27% 2.91M $38.81M
7 BVF Inc. 5.21% 2.88M $38.38M
8 T. Rowe Price Investment Management, Inc. 4.55% 2.51M $33.48M
9 Adage Capital Partners GP L.L.C. 4.07% 2.25M $29.98M
10 Trails Edge Capital Partners, LP 4.03% 2.23M $29.70M

Analyst View

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Latest News

Recent headlines for FDMT

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Google News ue, 29 Sep 2026

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FDMT — Frequently Asked Questions

What is the current share price of 4D Molecular Therapeutics, Inc. (FDMT)?

As of 2026-10-23 16:27 PDT, 4D Molecular Therapeutics, Inc. (FDMT) trades at $10.80 on NasdaqGS. Its 52-week range is $6.14 to $16.76.

What is the market capitalisation of FDMT?

4D Molecular Therapeutics, Inc. (FDMT) has a market capitalisation of $596.64M on NasdaqGS.

What is the P/E ratio of FDMT?

FDMT trades at a trailing price-to-earnings (P/E) ratio of -4.11. The industry average P/E is 25.45. Its price-to-book (P/B) ratio is 1.81.

What is the return on equity (ROE) of FDMT?

FDMT has a return on equity (ROE) of -43.25%. Its return on capital employed (ROCE) is -30.52%.

Is FDMT a good stock to buy?

This page provides a data-driven analysis of 4D Molecular Therapeutics, Inc. (FDMT), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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