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Dyadic International, Inc. DYAI PHARMA

Healthcare · Biotechnology · United States
https://www.dyadic.com
Company Profile ↓
$0.52
-36.57% 1Y
Mkt Cap$20.83M
P/E-2.48
P/B-7.79
52W High$1.47
52W Low$0.50
Book Value$-0.07
EPS (TTM)$-0.21

Company Overview

Dyadic International, Inc., together with its subsidiaries, a biotechnology platform company, develops, manufactures, and commercializes proteins and enzymes in the United States. The company offers Dapibus Protein Production Platform, a proprietary expression system designed to produce non-animal proteins and enzymes for non-pharmaceutical markets, including life sciences, food and nutrition, and bio-industrial sector; and C1 Protein Production Platform, a thermophilic fungal platform for large-scale production of proteins. It has a research and development agreement with VTT Technical Research Centre of Finland, Ltd; license agreement with Rubic One Health to develop various livestock vaccines; sub-license agreement with Phibro Animal Health/Abic Biological Laboratories to develop vaccines and treatments for livestock diseases; and collaboration with Scripps Research to evaluate monoclonal antibody and vaccine candidates targeting hantaviruses. Dyadic International, Inc. was founded in 1979 and is headquartered in Jupiter, Florida.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 19.2% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $3.09M (-11.6% YoY); net profit $-7.36M.
  • Trailing 12 Months Year-on-year growth — revenue -0.6%.
  • 5-Year Trend Long-term compounding — revenue CAGR 19.2%.

Growth & Price Performance

Compounded Sales Growth

5 Years:19.20%
1 Year:-0.60%

Stock Price Performance

1 Year:-36.57%
6 Months:-34.99%
3 Months:-25.70%
1 Month:-47.99%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 2% of range
$0.50 $1.47
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)25.40 · Oversold
Price Performance
1M-47.99%
3M-25.70%
6M-34.99%
1Y-36.57%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 19.2% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Trading 64.6% below its 52-week high.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-2.48
Industry PE
24.83
Forward P/E
-1.62
PEG Ratio
-
Book Value
$-0.07
Price to Book
-7.79
P/S
5.41
EV/EBITDA
-
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
19.20%
Profit 5Y
-
Revenue (YoY)
-0.60%
Earnings (YoY)
-

Profitability & Returns

ROCE
-114.93%
ROE
-
ROA
-62.99%
Profit Margin
-
Op Margin
-
Gross Margin
16.24%
EPS (Latest Qtr)
$-0.05
EPS (TTM)
$-0.21

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
1.14
Current Ratio
1.65
Debt
$5.05M
Total Assets
$7.81M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
22.90%
Chg in Prom Hold
-2.37%
FII / Inst Holding
12.32%
Chg in FII Hold
-2.38%

Financial Snapshot

Enterprise Value
$20.83M
Total Revenue (TTM)
$3.80M
EBITDA
-
Free Cash Flow
$-4.81M
Operating Cash Flow
$-7.40M
Shares Outstanding
40.06M
Gross Margin
16.24%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 DYAI Dyadic International, Inc. PHARMA 0.52 -2.48 $20.83M 0.00% -114.93% - 19.20% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue 184.33K161.29K262.96K402.53K390.87K454.51K315.37K524.27K416.36K460.52M937.09K692.93K648.43K658.55K879.60K978.05K837.16K397.06K334.62K385.90K1.96M393.57K966.63K1.16M1.11M
Operating Income -2.23M-1.82M-1.78M-2.44M-2.96M-1.94M-2.38M-2.80M-2.58M-3.32B-3.87M-3.32M-2.74M-3.32M-1.86M-2.05M-2.29M-1.72M-2.13M-2.04M-202.61K-2.00M-1.73M-1.93M-1.90M
Net Income -2.04M-1.60M-1.54M-2.18M-2.70M-1.70M-2.21M-2.65M-2.50M-3.29M-3.85M-1.72M-2.49M-3.29M-1.81M-956.44K-2.15M-1.61M-2.01M-2.05M-203.46K-2.03M-1.79M-1.98M-1.95M
Diluted EPS --------------------0.07-0.01-0.07-0.06-0.06-0.05
R&D Expense 576.88K601.20K476.63K692.37K818.24K841.34K755.45K1.12M986.05K1.81B2.21M1.90M1.34M1.83M743.59K810.57K917.55K716.35K522.72K515.63K460.24K494.98K629.38K571.87K476.07K

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 758.42K1.30M1.68M1.60M2.40M2.93M2.90M3.50M3.09M
Operating Income -7.13M-7.59M-9.28M-10.03M-14.73M-10.17M-8.23M-5.90M-7.19M
Net Income -2.14M-5.69M-8.31M-9.33M-13.07M-9.74M-6.80M-5.81M-7.36M
Diluted EPS --------0.20-0.23
R&D Expense 1.77M2.10M3.09M3.87M8.39M4.50M3.30M2.04M2.15M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -50.74M43.30M37.45M30.07M21.30M13.71M8.22M9.93M9.95M
Total Equity 57.69M49.98M42.45M35.86M28.45M18.39M11.09M5.88M2.47M1.23M
Cash & Equivalents -5.79M2.39M4.82M20.64M15.75M5.79M6.52M6.51M4.62M
Total Liabilities ----1.63M2.91M2.63M2.34M7.46M8.71M
Current Liabilities -768.89K849.64K1.59M1.63M2.56M2.45M2.25M2.45M3.69M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -1.69M-4.41M-5.78M-6.57M-11.28M-8.08M-6.73M-3.97M-5.70M
Investing Cash Flow -812.08K3.33M7.71M22.12M5.22M-2.37M7.45M-1.88M82.08K
Financing Cash Flow -6.22M-2.30M550.19K255.47K1.23M543.59K05.85M4.96M
Share Buybacks 6.22M2.30M0------

Ratios (Annual)

Figures in %.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------
Operating Margin % -939.7%-586.1%-552.2%-625.9%-612.7%-346.9%-283.9%-168.8%-232.8%
Net Margin % -281.6%-439.4%-494.2%-582.1%-543.7%-332.2%-234.4%-166.2%-238.3%
ROE % -4.3%-13.4%-23.2%-32.8%-71.1%-87.8%-115.6%-235.2%-597.6%
ROCE % -14.3%-17.9%-25.9%-35.2%-78.6%-90.2%-137.9%-78.9%-114.9%

Shareholding Pattern

Insiders
22.90%
Institutions
12.32%
Public Float
15.98%

Top Institutional Holders

#Holder% HeldSharesValue
1 Vanguard Capital Management LLC 3.47% 928.23K $385.22K
2 Chapin Davis, Inc. 3.32% 888.00K $368.52K
3 Apis Capital Advisors, LLC 3.01% 804.88K $334.03K
4 Truist Financial Corp 1.22% 326.20K $135.37K
5 Geode Capital Management, LLC 0.94% 250.91K $104.12K
6 Blackrock Inc. 0.74% 197.75K $82.06K
7 Vanguard Fiduciary Trust Co 0.52% 139.48K $57.88K
8 Marathon Capital Management 0.41% 110.00K $45.65K
9 Sage Mountain Advisors, LLC 0.40% 106.56K $44.22K
10 HighTower Advisors, LLC 0.30% 79.47K $32.98K

Analyst View

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Latest News

Recent headlines for DYAI

Google News Wed, 12 Aug 2026

Dyadic Says Pilot Process Boosted Transferrin Productivity ~80% - Stock Titan

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Google News hu, 28 May 2026

DYAI - Dyadic International Inc, DE Stock Price and Quote - Finviz

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Google News Sat, 11 Jul 2026

Analysts Expect Breakeven For Dyadic International, Inc. (NASDAQ:DYAI) Before Long - simplywall.st

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Google News hu, 25 Jun 2026

DYAI Forecast — Price Target — Prediction for 2027 - tradingview.com

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Google News Mon, 06 Jul 2026

Insider Sale: 10% owner at $DYAI Sells 25,281 Shares - Quiver Quantitative

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Google News Sat, 15 Aug 2026

Dyadic International Announces New Equity Financing Agreements - The Globe and Mail

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DYAI — Frequently Asked Questions

What is the current share price of Dyadic International, Inc. (DYAI)?

As of 2026-09-19 21:16 PDT, Dyadic International, Inc. (DYAI) trades at $0.52 on NasdaqCM. Its 52-week range is $0.50 to $1.47.

What is the market capitalisation of DYAI?

Dyadic International, Inc. (DYAI) has a market capitalisation of $20.83M on NasdaqCM.

What is the P/E ratio of DYAI?

DYAI trades at a trailing price-to-earnings (P/E) ratio of -2.48. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is -7.79.

Is DYAI a good stock to buy?

This page provides a data-driven analysis of Dyadic International, Inc. (DYAI), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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