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$31.31
+161.35% 1Y
Mkt Cap$5.43B
P/E-14.50
P/B11.38
52W High$42.84
52W Low$11.71
Book Value$2.72
EPS (TTM)$-2.16

Company Overview

Cogent Biosciences, Inc., a clinical-stage biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor in Phase 3 trial designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The company also develops CGT4859, a reversible and selective fibroblast growth factor receptor 2 inhibitor in Phase 1 trial for patients with documented FGFR mutations, including advanced cholangiocarcinoma; CGT4255, a novel ErbB2 mutant program, which is focused on actionable and underserved mutations in a solid tumor systemic and CNS involved indications; and CGT6297, a Novel PI3Ka mutant-selective inhibitor. It has a licensing agreement with Plexxikon Inc. for the research, development, and commercialization of bezuclastinib. Cogent Biosciences, Inc. is headquartered in Waltham, Massachusetts.

Recent Developments

  • Trailing 12 Months Year-on-year growth — revenue -65.0%.
  • 5-Year Trend Long-term compounding — revenue CAGR -2.0%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-1.99%
1 Year:-65.02%

Stock Price Performance

1 Year:+161.35%
6 Months:-13.36%
3 Months:-21.25%
1 Month:-0.32%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 63% of range
$11.71 $42.84
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)50.04 · Neutral
Price Performance
1M-0.32%
3M-21.25%
6M-13.36%
1Y+161.35%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Revenue declined at -2.0% CAGR over 5 years.
  • Trading 26.9% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-14.50
Industry PE
25.61
Forward P/E
-28.16
PEG Ratio
-
Book Value
$2.72
Price to Book
11.38
P/S
920.23
EV/EBITDA
-12.29
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-1.99%
Profit 5Y
-
Revenue (YoY)
-65.02%
Earnings (YoY)
-

Profitability & Returns

ROCE
-38.16%
ROE
-109.74%
ROA
-43.84%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.53
EPS (TTM)
$-2.16

Balance Sheet & Liquidity

Debt/Equity
0.46
Quick Ratio
13.36
Current Ratio
13.57
Debt
$244.26M
Total Assets
$903.01M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
0.42%
Chg in Prom Hold
-0.01%
FII / Inst Holding
115.22%
Chg in FII Hold
0.20%

Financial Snapshot

Enterprise Value
$5.43B
Total Revenue (TTM)
$7.87M
EBITDA
$-386.46M
Free Cash Flow
$-186.15M
Operating Cash Flow
$-307.54M
Shares Outstanding
173.52M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 COGT Cogent Biosciences, Inc. R2KR3KPHARMA 31.31 -14.50 $5.43B 0.00% -38.16% -109.74% -1.99% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,306.69 43.95 $1.16T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 267.61 31.05 $644.91B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 285.19 80.56 $503.96B 2.54% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 424.98 27.29 $381.46B 2.47% 9.74% 14.15% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPXR3KPHARMA 147.24 117.79 $363.27B 2.31% - 6.96% 5.64% 10.01%
7 NVS Novartis AG PHARMA 156.27 23.61 $297.02B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 172.57 25.80 $267.64B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 676.54 36.45 $250.15B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue 1.83M2.08M2.33M2.12M2.22M1.67M2.04M3.81M3.05M3.14M1.02M15.29M7.03M528.00K312.00K----------------
Operating Income -6.07M-6.03M-7.17M-6.88M-6.99M-9.44M-10.58M-9.00M-11.84M-10.54M-12.04M2.24M-6.14M-7.40M-57.20M-12.80M-17.29M-19.82M-31.42M-35.85M-36.82M-43.24M-47.09M-59.58M-62.40M-64.39M-75.41M-74.93M-75.58M-83.36M-103.61M
Net Income -5.94M-5.86M-7.00M-6.69M-6.74M-9.02M-10.17M-8.61M-11.69M-10.52M-11.92M2.30M-6.09M-7.39M-49.98M-11.73M-16.55M-19.08M-30.63M-34.93M-35.06M-38.59M-44.08M-55.38M-58.35M-58.95M-70.63M-71.99M-73.53M-80.93M-97.35M
Diluted EPS -----0.66-0.31-0.34-0.29-0.39-0.34-0.390.07-----0.43-0.48-0.68-0.71-0.50-0.55-0.59-0.64-0.49-0.43-0.52-0.52-0.53-0.50-0.53
R&D Expense 6.95M7.14M8.18M-8.14M9.13M10.25M-12.40M10.62M10.34M-9.50M5.13M5.00M8.21M12.39M14.80M25.47M29.48M29.94M36.04M38.87M50.13M52.70M54.29M63.61M63.03M62.20M68.99M75.36M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 8.36M9.73M22.50M7.87M-----
Operating Income -26.15M-36.01M-32.18M-82.20M-75.55M-147.84M-208.13M-275.94M-333.36M
Net Income -25.49M-34.53M-31.83M-74.81M-72.27M-140.24M-192.41M-255.86M-328.94M
Diluted EPS -----1.87-1.73-1.94-1.94-2.16
R&D Expense 29.83M38.28M43.71M25.74M55.91M121.63M173.75M232.66M269.78M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -49.12M85.93M49.42M250.92M232.09M300.81M313.44M327.90M937.61M
Total Equity -24.70M-48.85M60.23M31.76M234.67M214.18M255.74M257.80M256.29M636.37M
Cash & Equivalents -28.27M55.67M37.42M242.19M219.68M139.89M53.23M98.17M312.01M
Long Term Debt ---------222.90M
Total Liabilities -20.81M25.69M17.66M16.25M17.91M45.08M55.63M71.61M301.24M
Current Liabilities -11.19M24.95M13.25M13.09M17.08M26.85M38.17M55.71M63.95M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -25.84M-32.49M-41.51M-35.85M--118.64M-153.62M-207.79M-264.44M
Investing Cash Flow 13.59M-10.53M23.16M8.42M--124.72M-97.82M38.28M-399.53M
Financing Cash Flow -729.00K70.35M108.00K232.20M-163.56M163.54M214.45M878.23M
Capital Expenditure -912.00K-549.00K-33.00K---6.86M-2.80M-573.00K-1.55M
Free Cash Flow -26.75M-33.04M-41.55M---125.50M-156.42M-208.36M-266.00M
Net Change in Cash ------79.80M-87.91M44.94M214.26M

Ratios (Annual)

Figures in %.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------
Operating Margin % -312.8%-369.9%-143.0%-1,044.3%-----
Net Margin % -304.9%-354.8%-141.5%-950.4%-----
ROE % 52.2%-57.3%-100.2%-31.9%-33.7%-54.8%-74.6%-99.8%-51.7%
ROCE % -69.0%-59.0%-89.0%-34.6%-35.1%-54.0%-75.6%-101.4%-38.2%

Shareholding Pattern

Insiders
0.42%
Institutions
115.22%
Public Float
115.71%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 14.80% 25.68M $796.12M
2 Blackrock Inc. 10.00% 17.35M $537.93M
3 Vanguard Portfolio Management LLC 4.65% 8.07M $250.24M
4 Vanguard Capital Management LLC 4.27% 7.41M $229.78M
5 State Street Corporation 4.01% 6.96M $215.91M
6 Jupiter Topco LLC 3.82% 6.62M $205.37M
7 Fairmount Funds Management LLC 3.17% 5.50M $170.61M
8 Deerfield Management Company, L.P 2.88% 5.01M $155.19M
9 TCG Crossover Management, LLC 2.80% 4.85M $150.49M
10 Price (T.Rowe) Associates Inc 2.68% 4.65M $144.23M

Analyst View

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Latest News

Recent headlines for COGT

Google News Wed, 21 Oct 2026

Cogent Biosciences, Inc. (COGT) Stock Price, News, Quote & History - Yahoo! Finance Canada

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Google News Wed, 21 Oct 2026

If You Invested $1000 In Cogent Biosciences Stock 5 Years Ago, You Would Have This Much Today - Benzinga

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Google News Fri, 25 Sep 2026

Cogent Biosciences (COGT) Stock Trades At A Premium As FDA Accepts NDA - Yahoo Finance

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Google News Wed, 21 Oct 2026

COGT Nov 2026 31.000 put (COGT261120P00031000) stock historical prices and data - Yahoo Finance UK

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Google News ue, 20 Oct 2026

COGT Nov 2026 38.000 call (COGT261120C00038000) Stock Price, News, Quote & History - Yahoo! Finance Canada

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Google News ue, 20 Oct 2026

COGT Nov 2026 28.000 put (COGT261120P00028000) Stock Price, News, Quote & History - Yahoo! Finance Canada

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COGT — Frequently Asked Questions

What is the current share price of Cogent Biosciences, Inc. (COGT)?

As of 2026-10-22 16:30 PDT, Cogent Biosciences, Inc. (COGT) trades at $31.31 on NasdaqGS. Its 52-week range is $11.71 to $42.84.

What is the market capitalisation of COGT?

Cogent Biosciences, Inc. (COGT) has a market capitalisation of $5.43B on NasdaqGS.

What is the P/E ratio of COGT?

COGT trades at a trailing price-to-earnings (P/E) ratio of -14.50. The industry average P/E is 25.61. Its price-to-book (P/B) ratio is 11.38.

What is the return on equity (ROE) of COGT?

COGT has a return on equity (ROE) of -109.74%. Its return on capital employed (ROCE) is -38.16%.

Is COGT a good stock to buy?

This page provides a data-driven analysis of Cogent Biosciences, Inc. (COGT), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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