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Cogent Biosciences, Inc. COGT R2K

Healthcare · Biotechnology · United States
https://www.cogentbio.com
Company Profile ↓
$39.30
+254.37% 1Y
Mkt Cap$6.72B
P/E-17.62
P/B12.12
52W High$42.11
52W Low$10.86
Book Value$3.18
EPS (TTM)$-2.23

Company Overview

Cogent Biosciences, Inc., a clinical-stage biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor in Phase 3 trial designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The company also develops CGT4859, a reversible and selective fibroblast growth factor receptor 2 inhibitor in Phase 1 trial for patients with documented FGFR mutations, including advanced cholangiocarcinoma; CGT4255, a novel ErbB2 mutant program, which is focused on actionable and underserved mutations in a solid tumor systemic and CNS involved indications; and CGT6297, a Novel PI3Ka mutant-selective inhibitor. It has a licensing agreement with Plexxikon Inc. for the research, development, and commercialization of bezuclastinib. Cogent Biosciences, Inc. is headquartered in Waltham, Massachusetts.

Why Investors Should Care

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.39.

Recent Developments

  • Trailing 12 Months Year-on-year growth — revenue -65.0%.
  • 5-Year Trend Long-term compounding — revenue CAGR -2.0%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-1.99%
1 Year:-65.02%

Stock Price Performance

1 Year:+254.37%
6 Months:+13.06%
3 Months:+7.70%
1 Month:+18.73%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 91% of range
$10.86 $42.11
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)61.27 · Neutral
Price Performance
1M+18.73%
3M+7.70%
6M+13.06%
1Y+254.37%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Revenue declined at -2.0% CAGR over 5 years.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-17.62
Industry PE
25.88
Forward P/E
-41.12
PEG Ratio
-
Book Value
$3.18
Price to Book
12.12
P/S
718.55
EV/EBITDA
-16.74
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-1.99%
Profit 5Y
-
Revenue (YoY)
-65.02%
Earnings (YoY)
-

Profitability & Returns

ROCE
-38.16%
ROE
-85.72%
ROA
-38.13%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.53
EPS (TTM)
$-2.23

Balance Sheet & Liquidity

Debt/Equity
0.39
Quick Ratio
14.94
Current Ratio
15.14
Debt
$238.65M
Total Assets
$903.01M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
0.43%
Chg in Prom Hold
-
FII / Inst Holding
112.93%
Chg in FII Hold
0.63%

Financial Snapshot

Enterprise Value
$6.72B
Total Revenue (TTM)
$7.87M
EBITDA
$-359.49M
Free Cash Flow
$-167.25M
Operating Cash Flow
$-284.82M
Shares Outstanding
170.87M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 COGT Cogent Biosciences, Inc. R2K 39.30 -17.62 $6.72B 0.00% -38.16% -85.72% -1.99% -
2 LLY Eli Lilly and Company SPX 1,156.63 41.13 $1.03T 0.60% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 247.02 28.66 $594.63B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.11 119.08 $431.29B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 418.52 31.54 $380.08B 2.18% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 123.61 34.82 $305.29B 2.82% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 168.37 26.10 $261.12B 1.87% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 535.29 29.40 $198.93B 0.35% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 358.32 24.92 $193.39B 2.80% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue 1.83M2.08M2.33M2.12M2.22M1.67M2.04M3.81M3.05M3.14M1.02M15.29M7.03M528.00K312.00K----------------
Operating Income -6.07M-6.03M-7.17M-6.88M-6.99M-9.44M-10.58M-9.00M-11.84M-10.54M-12.04M2.24M-6.14M-7.40M-57.20M-12.80M-17.29M-19.82M-31.42M-35.85M-36.82M-43.24M-47.09M-59.58M-62.40M-64.39M-75.41M-74.93M-75.58M-83.36M-103.61M
Net Income -5.94M-5.86M-7.00M-6.69M-6.74M-9.02M-10.17M-8.61M-11.69M-10.52M-11.92M2.30M-6.09M-7.39M-49.98M-11.73M-16.55M-19.08M-30.63M-34.93M-35.06M-38.59M-44.08M-55.38M-58.35M-58.95M-70.63M-71.99M-73.53M-80.93M-97.35M
Diluted EPS -----0.66-0.31-0.34-0.29-0.39-0.34-0.390.07-----0.43-0.48-0.68-0.71-0.50-0.55-0.59-0.64-0.49-0.43-0.52-0.52-0.53-0.50-0.53
R&D Expense 6.95M7.14M8.18M-8.14M9.13M10.25M-12.40M10.62M10.34M-9.50M5.13M5.00M8.21M12.39M14.80M25.47M29.48M29.94M36.04M38.87M50.13M52.70M54.29M63.61M63.03M62.20M68.99M75.36M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 8.36M9.73M22.50M7.87M-----
Operating Income -26.15M-36.01M-32.18M-82.20M-75.55M-147.84M-208.13M-275.94M-333.36M
Net Income -25.49M-34.53M-31.83M-74.81M-72.27M-140.24M-192.41M-255.86M-328.94M
Diluted EPS -----1.87-1.73-1.94-1.94-2.16
R&D Expense 29.83M38.28M43.71M25.74M55.91M121.63M173.75M232.66M269.78M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -49.12M85.93M49.42M250.92M232.09M300.81M313.44M327.90M937.61M
Total Equity -24.70M-48.85M60.23M31.76M234.67M214.18M255.74M257.80M256.29M636.37M
Cash & Equivalents -28.27M55.67M37.42M242.19M219.68M139.89M53.23M98.17M312.01M
Long Term Debt ---------222.90M
Total Liabilities -20.81M25.69M17.66M16.25M17.91M45.08M55.63M71.61M301.24M
Current Liabilities -11.19M24.95M13.25M13.09M17.08M26.85M38.17M55.71M63.95M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -25.84M-32.49M-41.51M-35.85M-58.76M-118.64M-153.62M-207.79M-264.44M
Investing Cash Flow 13.59M-10.53M23.16M8.42M-1.72M-124.72M-97.82M38.28M-399.53M
Financing Cash Flow -729.00K70.35M108.00K232.20M37.98M163.56M163.54M214.45M878.23M
Capital Expenditure -912.00K-549.00K-33.00K--1.72M-6.86M-2.80M-573.00K-1.55M
Free Cash Flow -26.75M-33.04M-41.55M--60.48M-125.50M-156.42M-208.36M-266.00M

Ratios (Annual)

Figures in %.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------
Operating Margin % -312.8%-369.9%-143.0%-1,044.3%-----
Net Margin % -304.9%-354.8%-141.5%-950.4%-----
ROE % 52.2%-57.3%-100.2%-31.9%-33.7%-54.8%-74.6%-99.8%-51.7%
ROCE % -69.0%-59.0%-89.0%-34.6%-35.1%-54.0%-75.6%-101.4%-38.2%

Shareholding Pattern

Insiders
0.43%
Institutions
112.93%
Public Float
113.42%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 13.53% 23.12M $890.46M
2 Blackrock Inc. 9.39% 16.05M $617.89M
3 Deerfield Management Company, L.P 5.29% 9.04M $348.28M
4 Vanguard Portfolio Management LLC 4.29% 7.33M $282.41M
5 Vanguard Capital Management LLC 4.04% 6.89M $265.52M
6 Janus Henderson Group PLC 3.49% 5.97M $229.72M
7 State Street Corporation 3.31% 5.66M $218.10M
8 Fairmount Funds Management LLC 3.22% 5.50M $211.94M
9 RTW Investments LP 3.19% 5.46M $210.21M
10 TCG Crossover Management, LLC 2.90% 4.95M $190.50M

Analyst View

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Latest News

Recent headlines for COGT

Google News Wed, 15 Jul 2026

Cogent Bioscience (COGT) Files New Drug Application For Bezuclastinib - Yahoo Finance

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Google News Fri, 26 Jun 2026

COGT Forecast — Price Target — Prediction for 2027 - TradingView

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Google News Mon, 06 Jul 2026

Cogent Biosciences (COGT) director takes options in lieu of cash - Stock Titan

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Google News Sat, 11 Jul 2026

(COGT) Movement Within Algorithmic Entry Frameworks - Stock Traders Daily

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Google News Sun, 14 Jun 2026

Cogent Biosciences: A Pre-Commercial Biotech With Commercial-Stage Leverage (NASDAQ:COGT) - Seeking Alpha

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Google News Fri, 10 Jul 2026

Cogent Biosciences (COGT) Files FDA Application As Bezuclastinib Hype Meets A Pricey Valuation - simplywall.st

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COGT — Frequently Asked Questions

What is the current share price of Cogent Biosciences, Inc. (COGT)?

As of 2026-07-15 16:51 PDT, Cogent Biosciences, Inc. (COGT) trades at $39.30 on NasdaqGS. Its 52-week range is $10.86 to $42.11.

What is the market capitalisation of COGT?

Cogent Biosciences, Inc. (COGT) has a market capitalisation of $6.72B on NasdaqGS.

What is the P/E ratio of COGT?

COGT trades at a trailing price-to-earnings (P/E) ratio of -17.62. The industry average P/E is 25.88. Its price-to-book (P/B) ratio is 12.12.

What is the return on equity (ROE) of COGT?

COGT has a return on equity (ROE) of -85.72%. Its return on capital employed (ROCE) is -38.16%.

Is COGT a good stock to buy?

This page provides a data-driven analysis of Cogent Biosciences, Inc. (COGT), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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