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BlossomHill Therapeutics, Inc. BLSM PHARMA

Healthcare · Biotechnology · United States
https://bhtherapeutics.com
Company Profile ↓
$22.01
+37.56% 1Y
Mkt Cap$640.08M
P/E-9.02
P/B-4.86
52W High$22.01
52W Low$15.80
Book Value$-4.53
EPS (TTM)$-2.44

Company Overview

BlossomHill Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecule medicines that address medical needs in cancer treatment. Its pipeline includes BH-30643, an OMNI-EGFR inhibitor in clinical development for advanced EGFR-mutant non-small cell lung cancer (NSCLC), BH-501284, and BH-30236, a macrocyclic CLK (Cdc2-like kinase) inhibitor being evaluated in patients with relapsed or refractory acute myeloid leukemia (R/R AML) and higher-risk myelodysplastic syndrome (HR-MDS). BlossomHill Therapeutics, Inc. was incorporated in 2020 and is based in San Diego, California.

Why Investors Should Care

Strong Return on Equity

Generates a return on equity of 46.0%, reflecting efficient use of shareholder capital.

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.22.

Recent Developments

  • 5-Year Trend Long-term compounding — profit CAGR -97.3%.

Growth & Price Performance

Compounded Profit Growth

5 Years:-97.28%
1 Year:-

Stock Price Performance

1 Year:+37.56%
6 Months:-
3 Months:-
1 Month:-

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot
52-Week Range 100% of range
$15.80 $22.01
Trend Signals
  • RSI (14)78.33 · Overbought
Price Performance
1Y+37.56%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Strong return on equity of 46.0%.

CONS

  • Earnings shrank at -97.3% CAGR over 5 years.
  • RSI at 78 suggests overbought conditions.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-9.02
Industry PE
25.17
Forward P/E
-
PEG Ratio
-
Book Value
$-4.53
Price to Book
-4.86
P/S
-
EV/EBITDA
-2.78
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-97.28%
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-43.41%
ROE
45.97%
ROA
-37.16%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.72
EPS (TTM)
$-2.44

Balance Sheet & Liquidity

Debt/Equity
0.22
Quick Ratio
7.17
Current Ratio
7.40
Debt
$23.02M
Total Assets
$143.41M
Current Assets
$119.72M
Working Capital
$123.35M

Ownership

Promoter Holding
13.18%
Chg in Prom Hold
-
FII / Inst Holding
26.55%
Chg in FII Hold
5.90%

Financial Snapshot

Enterprise Value
$640.08M
Total Revenue (TTM)
$0
EBITDA
$-74.20M
Free Cash Flow
$-47.99M
Operating Cash Flow
$-56.89M
Shares Outstanding
29.08M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 BLSM BlossomHill Therapeutics, Inc. PHARMA 22.01 -9.02 $640.08M 0.00% -43.41% 45.97% - -97.28%
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2025Mar 2026
Revenue 00
Cost of Revenue --
Gross Profit --
Operating Expenses 11.45M22.11M
Operating Income -11.45M-22.11M
EBITDA -11.37M-21.98M
Interest Expense --
Pretax Income -10.48M-21.01M
Tax Provision --
Net Income -10.48M-21.01M
Diluted EPS -0.36-0.72

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2024Dec 2025
Revenue 00
Cost of Revenue --
Gross Profit --
Operating Expenses 36.40M64.02M
Operating Income -36.40M-64.02M
EBITDA -36.05M-63.58M
Interest Expense --
Pretax Income -30.70M-60.55M
Tax Provision --
Net Income -30.70M-60.55M
Diluted EPS -1.06-2.08

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2024Dec 2025
Total Assets 106.78M162.97M
Current Assets 104.17M138.83M
Cash & Equivalents 100.15M136.68M
Inventory --
Receivables --
Total Liabilities 179.66M294.70M
Current Liabilities 6.77M15.48M
Long Term Debt --
Total Debt 525.00K22.40M
Total Equity -72.88M-131.73M
Shares Outstanding 29.08M29.08M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2024Dec 2025
Operating Cash Flow -31.42M-46.92M
Investing Cash Flow -92.00K-1.07M
Financing Cash Flow 17.56M84.53M
Capital Expenditure -92.00K-1.07M
Free Cash Flow -31.51M-47.99M
Net Change in Cash -13.95M36.53M

Ratios (Annual)

Figures in %.

Metric Dec 2024Dec 2025
Gross Margin % --
Operating Margin % --
Net Margin % --
ROE % 42.1%46.0%
ROCE % -36.4%-43.4%

Shareholding Pattern

Insiders
13.18%
Institutions
26.55%
Public Float
30.58%

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for BLSM

Google News Wed, 02 Sep 2026

BlossomHill Therapeutics (NASDAQ:BLSM) Stock Rating Upgraded by Guggenheim - marketbeat.com

<a href="https://news.google.com/rss/articles/CBMizwFBVV95cUxPUlpjQldwMDQ2X3huTndzSVBuUnNCeFRkOEhDdGVxemZLeUlyY1o1ellfVVV1WFV1MVU3Uy1EcHZuS2lEbkxUbEFFSlZ5Mm9oMXNWVU5uUUFqOGxMOG03dmdfSXF6SjBuZ2g5RVdSemlUcEplV20xcDRTZUJCa2Z3aEt6eVRIN3dhNlZCcG…

Google News ue, 01 Sep 2026

Patients whose lung cancer develops a specific resistance mutation after a targeted drug stops working have no approved pills aimed at it. BlossomHill Therapeutics plans to present updated trial data on Sept. 15. - Stock Titan

<a href="https://news.google.com/rss/articles/CBMiwAFBVV95cUxOVGhyUDJNSC1FRTdxRVhJS3ljejM1TzBWY04wOWgxODY4eVVweDNwSlJtUGltRUpSaUxPVm1YRXdTZHNDWEJpclViYUUxTmFlSkxRc2ZaendwZU9PaHR1VTFkV1M0TzNJaTdOYVRmZGNsQWF1M2tTNVlhQk4wdl9CcjFReFFuMmlrVDJicm…

Google News Mon, 31 Aug 2026

BlossomHill Therapeutics, Inc. - Common Stock (Nasdaq:BLSM) Stock Quote - The Chronicle-Journal

<a href="https://news.google.com/rss/articles/CBMiggFBVV95cUxNZng5WDBFemk2el9obDlrNXpYWmVRQUNxWXBhRk1pU2xHc0tRY1psM0ZFRmlPT1psSTNlbUp2bUNOOWx2ZU5QVVVLcTJUdEdnSnFLcC15TzVnVkJwaVJYV2l1aDh0c0h1aGhNaEh2cVZrSlZMTFFhMjZGUnhPMDM0UGtn?oc=5" target=…

Google News Sat, 08 Aug 2026

BLSM - BlossomHill Therapeutics Inc Stock Price and Quote - Finviz

<a href="https://news.google.com/rss/articles/CBMiRkFVX3lxTE9OOEw2VWxhQWJzNzhkYjhJd19ZWEhnb1Q1a3YxNHZOdXhQMFNTNlctM3ZRNnlSRklKWVFoMGpGSXJjTWtWRFE?oc=5" target="_blank">BLSM - BlossomHill Therapeutics Inc Stock Price and Quote</a>&nbsp;&nbsp…

Google News hu, 03 Sep 2026

BlossomHill Therapeutics (NASDAQ:BLSM) Shares Gap Up - Here's Why - marketbeat.com

<a href="https://news.google.com/rss/articles/CBMivAFBVV95cUxNUzZiY0YxZ1RwU1lhc2xHdUV3RXdGZVMtbDlNTTBqd2l1QnpjSnBwU0lkbGtGMC1aRy03ZC1pYm85cDMxNDlLbENESDlHT2xhMFdfdWFLUWVKMHhsREJ2QWdacUpJcDZCemliUFVvR1VRN2lLS2FfOTRfYkFpbGp0aE5jb1piWmdkMUlqb0…

Google News Wed, 26 Aug 2026

BlossomHill (NASDAQ: BLSM) insider buys at $16 and gets options - Stock Titan

<a href="https://news.google.com/rss/articles/CBMiwAFBVV95cUxQS1pMT0huMHlFNE0xS0lMczBfN0dfUlZleDJnR1p6T2hzVU1hMXlCTVhLWHN2b24zNXQ5N24xNTItN1FHbDhQX3EtTUxKR0J6X0xUYWs2T0lfOVYyZ0xmUm01RkM1c2NFdnVmSktBckJOQUlpTkMxMy1FcEt2N0h5eGVpck5IWklXWERDcU…

BLSM — Frequently Asked Questions

What is the current share price of BlossomHill Therapeutics, Inc. (BLSM)?

As of 2026-09-07 16:24 PDT, BlossomHill Therapeutics, Inc. (BLSM) trades at $22.01 on NasdaqGS. Its 52-week range is $15.80 to $22.01.

What is the market capitalisation of BLSM?

BlossomHill Therapeutics, Inc. (BLSM) has a market capitalisation of $640.08M on NasdaqGS.

What is the P/E ratio of BLSM?

BLSM trades at a trailing price-to-earnings (P/E) ratio of -9.02. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is -4.86.

What is the return on equity (ROE) of BLSM?

BLSM has a return on equity (ROE) of 45.97%. Its return on capital employed (ROCE) is -43.41%.

Is BLSM a good stock to buy?

This page provides a data-driven analysis of BlossomHill Therapeutics, Inc. (BLSM), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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