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Anavex Life Sciences Corp. AVXL R2K

Healthcare · Biotechnology · United States
https://www.anavex.com
Company Profile ↓
$2.43
-78.83% 1Y
Mkt Cap$225.19M
P/E-5.28
P/B1.83
52W High$13.41
52W Low$2.35
Book Value$1.37
EPS (TTM)$-0.46

Company Overview

Anavex Life Sciences Corp. operates as a biopharmaceutical company. It engages in developing innovative treatments for Alzheimer's disease, Parkinson's disease, schizophrenia, neurodevelopmental, neurodegenerative, and rare diseases, including Rett syndrome, and other central nervous system (CNS) disorders, pain, and various types of cancer . Its lead drug candidate, ANAVEX 2-73 (blarcamesine), has completed a Phase 2a and a Phase 2b/3 clinical trial for Alzheimer's disease; a Phase 2 proof-of-concept study in Parkinson's disease dementia; and a Phase 2 and a Phase 3 study in adult patients and one Phase 2/3 study in pediatric patients with Rett syndrome. Its ANAVEX 2-73 is an orally available drug candidate designed to restore cellular homeostasis by targeting SIGMAR1 and muscarinic receptors. The ANAVEX 2-73 also exhibited anticonvulsant, anti-amnesic, neuroprotective, and anti-depressant properties in animal models, indicating its potential to treat additional CNS disorders, including epilepsy. The company's ANAVEX 3-71, which targets SIGMAR1 and M1 muscarinic receptors, is a clinical stage drug candidate demonstrating disease-modifying activity against Alzheimer's disease in transgenic (3xTg-AD) mice, including cognitive deficits, amyloid, and tau pathologies. Anavex Life Sciences Corp. was incorporated in 2004 and is headquartered in New York, New York.

Growth & Price Performance

Stock Price Performance

1 Year:-78.83%
6 Months:-43.22%
3 Months:-21.86%
1 Month:-2.80%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 1% of range
$2.35 $13.41
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)40.65 · Neutral
Price Performance
1M-2.80%
3M-21.86%
6M-43.22%
1Y-78.83%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 81.9% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-5.28
Industry PE
25.41
Forward P/E
-4.42
PEG Ratio
-
Book Value
$1.37
Price to Book
1.83
P/S
-
EV/EBITDA
-
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-54.15%
ROE
-33.63%
ROA
-21.56%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.06
EPS (TTM)
$-0.46

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
20.81
Current Ratio
20.87
Debt
$0
Total Assets
$132.99M
Current Assets
$132.99M
Working Capital
$94.87M

Ownership

Promoter Holding
3.12%
Chg in Prom Hold
-
FII / Inst Holding
43.87%
Chg in FII Hold
-

Financial Snapshot

Enterprise Value
$225.19M
Total Revenue (TTM)
$0
EBITDA
$-46.38M
Free Cash Flow
$-21.83M
Operating Cash Flow
$-34.08M
Shares Outstanding
92.67M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 AVXL Anavex Life Sciences Corp. R2K 2.43 -5.28 $225.19M 0.00% -54.15% -33.63% - -
2 LLY Eli Lilly and Company SPX 1,152.54 41.02 $1.03T 0.61% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 253.85 29.45 $611.07B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.78 119.40 $432.48B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 425.19 32.02 $386.13B 2.27% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 120.78 34.02 $298.31B 2.86% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 164.50 24.81 $255.12B 1.77% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 534.07 29.33 $198.47B 0.40% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 355.25 24.69 $191.73B 2.84% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Jun 2013Dec 2013Mar 2014Jun 2014Dec 2014Mar 2015Jun 2015Dec 2015Mar 2016Jun 2016Dec 2016Mar 2017Jun 2017Dec 2017Mar 2018Jun 2018Dec 2018Mar 2019Jun 2019Dec 2019Mar 2020Jun 2020Dec 2020Mar 2021Jun 2021Dec 2021Mar 2022Jun 2022Dec 2022Mar 2023Jun 2023Dec 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025
Revenue -----------------------------------00000
Cost of Revenue ----------------------------------------
Gross Profit ----------------------------------------
Operating Expenses -----------------------------------13.58M12.42M14.31M11.48M6.78M
Operating Income -125.98K-309.61K-1.02M-998.83K-770.68K-858.34K-1.51M-------------------11.72M-11.52M-12.46M-15.38M-14.19M-13.53M-11.38M-12.62M-14.60M--13.58M-12.42M-14.31M-11.48M-6.78M
EBITDA ------------------------------------13.58M-12.42M-14.31M-6.49M-6.78M
Interest Expense ----------------------------------0-----
Pretax Income ------------------------------------12.11M-11.20M-13.24M-9.83M-5.66M
Tax Provision -----------------------------------124.00K0---18.00K
Net Income -151.92K358.64K-1.02M-1.01M-786.72K-1.72M-4.24M-3.95M-2.03M-2.24M-3.15M-1.55M-3.61M-4.06M-4.75M-2.85M-6.92M-7.25M-6.52M-6.59M-7.24M-6.49M-7.86M-8.16M-10.18M-10.88M-10.44M-12.37M-12.97M-13.11M-11.28M-8.62M-10.55M-12.21M--12.11M-11.20M-13.24M-9.83M-5.68M
Diluted EPS -0.01-0.01-0.03-0.03-0.06-0.12-0.22-0.12-0.06-0.06-0.08-0.04-----------------0.17-0.17-0.14-0.11-0.13-0.14--0.14-0.13-0.16-0.11-0.06
R&D Expense 39.02K5.18K118.15K265.01K318.62K407.15K799.46K1.16M1.09M1.16M2.04M2.49M2.30M2.69M3.25M3.00M5.71M6.08M5.76M6.35M6.05M6.73M7.93M6.72M8.96M8.66M8.60M9.27M12.07M11.31M10.28M8.68M9.73M11.81M-10.45M9.89M9.96M-4.66M

Profit & Loss (Annual)

Figures in USD.

Metric Sep 2005Sep 2006Sep 2007Sep 2008Sep 2009Sep 2010Sep 2011Sep 2012Sep 2013Sep 2014Sep 2015Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Revenue -----------------0000
Cost of Revenue ---------------------
Gross Profit ---------------------
Operating Expenses -----------------50.99M55.74M52.80M51.37M
Operating Income ------5.65M-6.18M-4.32M-2.14M-2.97M------31.09M--50.99M-55.74M-52.80M-51.37M
EBITDA ------------------47.62M-46.54M-43.00M-46.38M
Interest Expense -----------------0964.00K00
Pretax Income ------------------47.62M-47.51M-43.00M-46.38M
Tax Provision ----------------268.00K358.00K7.00K0-
Net Income -91.62K-25.53K-1.58M-5.35M-5.50M-8.78M-7.31M-8.30M-3.70M-9.97M-12.11M-14.74M-13.46M-17.25M-26.29M-26.28M--47.98M-47.51M-43.00M-46.38M
Diluted EPS ------0.41-0.29-0.29-0.12-1.02-0.65-0.42------0.62-0.60-0.52-0.54
R&D Expense -----2.73M2.60M2.65M263.85K732.39K2.27M7.25M10.67M13.34M22.26M25.23M32.98M37.92M43.72M41.84M37.59M

Balance Sheet (Annual)

Figures in USD.

Metric Sep 2004Sep 2005Sep 2006Sep 2007Sep 2008Sep 2009Sep 2010Sep 2011Sep 2012Sep 2013Sep 2014Sep 2015Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Total Assets ------329.85K203.04K13.15K393.45K7.35M15.47M9.50M27.84M26.21M25.33M34.54M-152.71M154.39M135.57M103.81M
Current Assets ------------------152.71M154.39M135.57M103.81M
Cash & Equivalents ------------9.19M27.44M22.93M22.19M29.25M-149.16M151.02M132.19M102.58M
Inventory ----------------------
Receivables ------------------3.19M2.71M2.45M809.00K
Total Liabilities ------3.29M1.35M2.89M2.86M7.16M2.66M3.19M3.58M-5.04M7.31M-10.21M12.53M15.30M8.95M
Current Liabilities --------2.89M1.95M1.44M2.66M3.19M3.58M3.88M5.04M--10.21M12.53M15.30M8.95M
Long Term Debt ----------5.72M332----------
Total Debt ----------------------
Total Equity 25.61K-26.02K-15.51K-462.50K-2.29M-3.86M-2.96M-1.14M-2.88M-2.46M192.63K12.81M6.31M25.88M22.32M20.29M27.24M-142.49M141.85M120.26M94.87M
Shares Outstanding ------------------77.94M82.07M84.80M86.67M

Cash Flows (Annual)

Figures in USD.

Metric Sep 2010Sep 2011Sep 2012Sep 2013Sep 2014Sep 2015Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Operating Cash Flow -4.59M-3.80M-1.69M-777.57K-2.66M-4.23M-9.24M-9.02M-12.58M-18.53M-21.29M--24.24M-27.79M-30.81M-39.04M
Investing Cash Flow -3.31K000-3.02K-----------
Financing Cash Flow 4.51M3.67M1.57M1.11M9.58M12.26M3.13M27.27M8.07M17.78M28.35M-21.29M29.65M11.97M9.43M
Capital Expenditure -----3.02K-----------
Free Cash Flow -----2.66M--------24.24M-27.79M-30.81M-39.04M
Net Change in Cash -------------2.95M1.87M-18.84M-29.61M

Ratios (Annual)

Figures in %.

Metric Sep 2005Sep 2006Sep 2007Sep 2008Sep 2009Sep 2010Sep 2011Sep 2012Sep 2013Sep 2014Sep 2015Sep 2016Sep 2017Sep 2018Sep 2019Sep 2020Sep 2021Sep 2022Sep 2023Sep 2024Sep 2025
Gross Margin % ---------------------
Operating Margin % ---------------------
Net Margin % ---------------------
ROE % 352.1%164.6%341.6%233.5%142.6%296.7%639.6%288.7%150.2%-5,175.0%-94.5%-233.6%-52.0%-77.3%-129.6%-96.5%--33.7%-33.5%-35.8%-48.9%
ROCE % -------150.3%137.1%-50.2%--------35.8%-39.3%-43.9%-54.1%

Shareholding Pattern

Insiders
3.12%
Institutions
43.87%
Public Float
45.28%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 8.21% 7.61M $20.43M
2 State Street Corporation 4.87% 4.51M $12.11M
3 Vanguard Capital Management LLC 4.17% 3.86M $10.37M
4 Two Sigma Investments, LP 3.50% 3.25M $8.72M
5 Geode Capital Management, LLC 2.36% 2.19M $5.88M
6 Susquehanna International Group, LLP 1.07% 995.66K $2.67M
7 Summit Financial, LLC 1.01% 940.46K $2.53M
8 Bank of America Corporation 0.93% 863.15K $2.32M
9 Goldman Sachs Group Inc 0.87% 804.43K $2.16M
10 Vanguard Portfolio Management LLC 0.85% 783.15K $2.10M

Analyst View

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Latest News

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Yahoo Finance Fri, 22 May 2026

Anavex Life Sciences Receives Expected Nasdaq Delinquency Notification

NEW YORK, May 22, 2026 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company focused on developing innovative treatments for central nervous system (CNS) disord…

Yahoo Finance Wed, 06 May 2026

CEO Transition and Delayed SEC Filing Put Anavex (AVXL) Leadership Changes in Focus

Anavex appointed former clinical development executive Terrie Kellmeyer as interim CEO following the departure of longtime chief executive Christopher Missling, while also signaling a delay in its quarterly SEC filing. Key Investor Takeaway…

Yahoo Finance Wed, 06 May 2026

Anavex Life Sciences Board of Directors Appoints Former Senior Vice President of Clinical Development Terrie Kellmeyer, PhD, as Interim Chief Executive Officer

NEW YORK, May 06, 2026 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company focused on developing innovative treatments for Alzheimer’s disease, Parkinson’s di…

Yahoo Finance Mon, 04 May 2026

AMD downgraded, Airbnb upgraded: Wall Street's top analyst calls

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AVXL — Frequently Asked Questions

What is the current share price of Anavex Life Sciences Corp. (AVXL)?

As of 2026-07-14 21:23 PDT, Anavex Life Sciences Corp. (AVXL) trades at $2.43 on NasdaqGS. Its 52-week range is $2.35 to $13.41.

What is the market capitalisation of AVXL?

Anavex Life Sciences Corp. (AVXL) has a market capitalisation of $225.19M on NasdaqGS.

What is the P/E ratio of AVXL?

AVXL trades at a trailing price-to-earnings (P/E) ratio of -5.28. The industry average P/E is 25.41. Its price-to-book (P/B) ratio is 1.83.

What is the return on equity (ROE) of AVXL?

AVXL has a return on equity (ROE) of -33.63%. Its return on capital employed (ROCE) is -54.15%.

Is AVXL a good stock to buy?

This page provides a data-driven analysis of Anavex Life Sciences Corp. (AVXL), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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