🇺🇸 US Stock Screener ← Switch market ★ Elite Club ⚡ StockGenie AI

Amylyx Pharmaceuticals, Inc. AMLX R2K

Healthcare · Drug Manufacturers - Specialty & Generic · United States
https://amylyx.com

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

READ MORE ›
$14.35
+178.64% 1Y

Market & Price

Market Cap
$1.60B
Current Price
$14.35
High / Low (52W)
$18.36 / $4.92
Beta
-0.10

Valuation

Stock P/E
-
Industry PE
23.65
Forward P/E
-
PEG Ratio
-
Book Value
$2.46
Price to Book
5.83
P/S
-
EV/EBITDA
-8.32
Dividend Yield
-

Profitability & Returns

ROCE
-49.46%
ROE
-63.26%
ROA
-38.79%
Profit Margin
0.00%
Op Margin
0.00%
EPS (Latest Qtr)
$-0.37
EPS (TTM)
$-1.48

Balance Sheet & Liquidity

Debt/Equity
2.06
Quick Ratio
17.53
Current Ratio
17.85
Debt
$5.63M
Total Assets
$332.64M
Current Assets
$323.67M
Working Capital
$300.98M

Ownership

Promoter Holding
7.92%
Chg in Prom Hold
0.00%
FII / Inst Holding
105.09%
Chg in FII Hold
-0.00%

Financial Snapshot

Enterprise Value
$1.32B
Total Revenue (TTM)
-
EBITDA
$-158.80M
Free Cash Flow
$-71.52M
Operating Cash Flow
$-120.40M
Shares Outstanding
111.19M
Gross Margin
0.00%
Payout Ratio
0.00%

Growth (CAGR)

Revenue 5Y
-33.33%
Profit 5Y
9.01%
Revenue (YoY)
-
Earnings (YoY)
-

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Revenue declined at -33.3% CAGR over 5 years.

* The pros and cons are auto-generated from financial metrics.

Price Chart

Robinhood TradingView StockAnalysis

Fundamental Growth

Figures from the latest reported periods. CAGR is computed across the displayed window (quarterly CAGR is annualised assuming 4 quarters per year).

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 AMLX Amylyx Pharmaceuticals, Inc. R2K 14.35 - $1.60B - -49.46% -63.26% -33.33% 9.01%
2 LLY Eli Lilly and Company SPX 1,105.00 39.21 $985.37B 0.63% 38.44% 107.46% 31.69% 48.96%
3 JNJ Johnson & Johnson SPX 225.33 26.11 $542.42B 2.38% 23.13% 26.42% 5.60% 14.32%
4 UNH UnitedHealth Group Incorporated SPX 380.31 28.66 $345.38B 2.32% 9.60% 12.18% 11.35% -15.69%
5 MRK Merck & Co., Inc. SPX 118.72 33.44 $293.22B 2.86% 20.66% 18.94% 3.12% 7.93%
6 TMO Thermo Fisher Scientific Inc. SPX 492.51 27.11 $183.03B 0.38% 9.17% 13.52% -0.27% -1.19%
7 AMGN Amgen Inc. NDXSPX 336.79 23.42 $181.77B 2.99% 18.02% 101.32% 11.77% 5.58%
8 GILD Gilead Sciences, Inc. NDXSPX 134.43 18.29 $166.90B 2.44% 22.92% 43.36% 2.57% 22.83%
9 ISRG Intuitive Surgical, Inc. NDXSPXAI 424.64 51.53 $150.39B - 15.96% 17.23% 17.39% 29.26%
Ad space

Quarterly Results

Figures in USD.

Metric Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue -----345.00K71.43M98.22M102.69M88.64M-1.02M--00000
Cost of Revenue -------------00000
Gross Profit -------------00000
Operating Expenses -------------37.80M42.86M36.03M36.60M43.78M
Operating Income -12.87M-18.59M-22.92M-47.81M-54.25M-54.68M-2.05M20.20M18.72M-122.13M-76.29M---37.80M-42.86M-36.03M-36.60M-43.78M
EBITDA --------------37.65M-42.72M-35.91M-36.50M-43.68M
Interest Expense ------------------
Pretax Income --------------35.91M-41.44M-34.39M-32.95M-41.28M
Tax Provision -------------635.00K00046.00K-
Net Income -14.52M-21.92M-23.14M-47.85M-54.07M-53.76M1.57M22.07M20.89M-118.79M-72.70M---35.91M-41.44M-34.39M-33.00M-41.28M
Diluted EPS --3.41-3.42-0.93-0.93-0.920.020.310.30-1.75-1.07---0.42-0.46-0.37-0.30-0.37
R&D Expense 6.86M10.93M12.85M21.46M24.26M24.91M24.19M29.04M30.04M36.61M23.35M21.24M-22.12M27.22M19.86M-27.61M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -22.23M380.79M87.37M0
Cost of Revenue -2.99M25.44M124.63M0
Gross Profit -19.24M355.35M-37.26M0
Operating Expenses -220.58M316.54M218.41M153.29M
Operating Income --201.34M38.80M-255.68M-153.29M
EBITDA --200.85M39.89M-254.77M-152.77M
Interest Expense 0----
Pretax Income --197.60M54.30M-302.14M-144.69M
Tax Provision -774.00K5.03M-393.00K46.00K
Net Income --198.38M49.27M-301.74M-144.74M
Diluted EPS -1.59-3.390.70-4.43-
R&D Expense 44.04M93.45M128.19M104.08M90.40M

Compounded Sales Growth

5 Years:-33.33%
1 Year:-

Compounded Profit Growth

5 Years:9.01%
1 Year:-

Stock Price Performance

1 Year:+178.64%
6 Months:-3.56%
3 Months:-5.41%
1 Month:-8.01%

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --391.45M517.45M193.63M332.64M
Current Assets --382.13M464.67M189.43M323.67M
Cash & Equivalents --62.53M170.20M77.39M226.65M
Inventory -09.77M38.32M0-
Receivables --15.31M40.05M447.00K88.00K
Total Liabilities --50.85M84.02M28.87M27.39M
Current Liabilities --46.61M82.04M28.41M22.69M
Long Term Debt ------
Total Debt --6.28M4.24M1.98M5.96M
Total Equity -66.72M-340.61M433.43M164.76M305.26M
Shares Outstanding --66.51M67.71M68.63M109.88M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow --179.87M11.92M-167.65M-123.34M
Investing Cash Flow --238.99M92.05M75.65M14.04M
Financing Cash Flow -431.79M3.54M348.00K257.03M
Capital Expenditure --2.53M-1.24M-157.00K-138.00K
Free Cash Flow --182.40M10.68M-167.80M-123.48M
Net Change in Cash -12.93M107.52M-91.64M147.72M

Ratios (Annual)

Figures in %.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -86.5%93.3%-42.6%-
Operating Margin % --905.7%10.2%-292.6%-
Net Margin % --892.4%12.9%-345.4%-
ROE % --58.2%11.4%-183.1%-47.4%
ROCE % --58.4%8.9%-154.7%-49.5%

Shareholding Pattern

Insiders
7.92%
Institutions
105.09%
Public Float
114.13%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 14.96% 16.63M $238.65M
2 Blackrock Inc. 7.94% 8.83M $126.69M
3 Perceptive Advisors Llc 7.45% 8.28M $118.89M
4 TCG Crossover Management, LLC 5.62% 6.24M $89.60M
5 Commodore Capital Lp 5.08% 5.65M $81.08M
6 Janus Henderson Group PLC 4.48% 4.99M $71.55M
7 Saturn V Capital Management LP 3.91% 4.35M $62.42M
8 Vanguard Capital Management LLC 3.72% 4.14M $59.43M
9 Adage Capital Partners GP L.L.C. 3.20% 3.56M $51.10M
10 First Light Asset Management, LLC 2.87% 3.19M $45.79M

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for AMLX

No recent headlines available.

Explore More

📊 Healthcare Sector 🔍 All Stock Screens 📈 Technical Screens 💰 Fundamental Screens 🔄 Swing Trading Setups 📐 Chart Patterns 📅 Earnings Calendar 📋 All USA Stocks