Akebia Therapeutics, Inc. AKBA R2K
Company Overview
Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. Its product portfolio includes Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent (DD) and non-dialysis dependent (NDD) patients; and Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD and the treatment of iron deficiency anemia in adult patients with NDD-CKD. The company is also developing AKB-9090, which is in Phase 2 clinical trial for treating cardiac surgery-related acute kidney injury and acute respiratory distress syndrome; and AKB-10108 for the treatment of retinopathy of prematurity in neonates. The company has license and collaboration agreements with Tanabe Pharma Corporation for the development and commercialization of Vafseo in Japan and other Asian countries; Vafseo License and Collaboration Agreements; CSL Vifor Agreements; Averoa License Agreement; License Agreement with Panion & BF Biotech, Inc.; Cyclerion Therapeutics License Agreement; and Q32 Asset Purchase Agreement. Akebia Therapeutics, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.
Why Investors Should Care
Net profit has compounded at 31.4% per year over the last five years.
Generates positive free cash flow, funding growth and shareholder returns internally.
Recent Developments
- Dec 2025 Revenue of $236.20M (+47.5% YoY); net profit $-5.34M.
- Trailing 12 Months Year-on-year growth — revenue -6.6%.
- 5-Year Trend Long-term compounding — revenue CAGR -6.9%, profit CAGR 31.4%.
Growth & Price Performance
Compounded Sales Growth
| 5 Years: | -6.88% |
| 1 Year: | -6.60% |
Compounded Profit Growth
| 5 Years: | 31.44% |
| 1 Year: | - |
Stock Price Performance
| 1 Year: | -65.24% |
| 6 Months: | -1.43% |
| 3 Months: | -11.54% |
| 1 Month: | +49.19% |
Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.
- Price vs 50-DMAAbove
- Price vs 200-DMABelow
- RSI (14)67.55 · Neutral
Auto-generated from price history and fundamentals; not investment advice.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth Charts
No fundamental data available for this stock.
Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.
PROS
- Profit CAGR of 31.4% over 5 years.
- Generates positive free cash flow.
CONS
- Revenue declined at -6.9% CAGR over 5 years.
- Trading 65.6% below its 52-week high.
- In a downtrend (50-DMA below 200-DMA).
* The pros and cons are auto-generated from financial metrics.
Valuation
Growth (CAGR)
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | AKBA Akebia Therapeutics, Inc. R2K | 1.38 | -17.25 | $370.20M | 0.00% | 9.58% | -78.95% | -6.88% | 31.44% |
| 2 | LLY Eli Lilly and Company SPX | 1,156.63 | 41.13 | $1.03T | 0.60% | - | 107.46% | 7.20% | 11.41% |
| 3 | JNJ Johnson & Johnson SPX | 247.02 | 28.66 | $594.63B | 2.23% | 14.88% | 26.42% | 2.43% | 4.76% |
| 4 | ABBV AbbVie Inc. SPX | 244.11 | 119.08 | $431.29B | 3.04% | 10.47% | -129.24% | 1.75% | -29.06% |
| 5 | UNH UnitedHealth Group Incorporated SPX | 418.52 | 31.54 | $380.08B | 2.18% | 9.74% | 12.18% | 10.40% | 5.43% |
| 6 | MRK Merck & Co., Inc. SPX | 123.61 | 34.82 | $305.29B | 2.82% | - | 18.94% | 5.64% | 10.01% |
| 7 | AZN AstraZeneca PLC NDX | 168.37 | 26.10 | $261.12B | 1.87% | 15.97% | 23.48% | 9.82% | 45.96% |
| 8 | TMO Thermo Fisher Scientific Inc. SPX | 535.29 | 29.40 | $198.93B | 0.35% | 8.14% | 13.52% | 8.81% | 12.95% |
| 9 | AMGN Amgen Inc. NDXSPX | 358.32 | 24.92 | $193.39B | 2.80% | 18.02% | 101.32% | 11.77% | 5.58% |
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios
Quarterly Results
Figures in USD.
| Metric | Sep 2015 | Dec 2015 | Mar 2016 | Jun 2016 | Sep 2016 | Dec 2016 | Mar 2017 | Jun 2017 | Sep 2017 | Dec 2017 | Mar 2018 | Jun 2018 | Sep 2018 | Dec 2018 | Mar 2019 | Jun 2019 | Sep 2019 | Dec 2019 | Mar 2020 | Jun 2020 | Sep 2020 | Dec 2020 | Mar 2021 | Jun 2021 | Sep 2021 | Mar 2022 | Jun 2022 | Sep 2022 | Mar 2023 | Jun 2023 | Sep 2023 | Mar 2024 | Jun 2024 | Sep 2024 | Dec 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | 28.52M | 41.28M | - | 45.93M | 48.79M | 53.17M | - | 72.67M | 100.80M | 91.98M | - | 88.48M | 90.14M | 59.99M | - | 52.30M | 52.91M | 48.76M | 61.70M | 126.36M | 48.71M | 40.01M | 56.38M | 42.05M | 32.61M | 43.65M | - | - | 57.34M | 62.47M | 58.77M | 57.62M | 53.54M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.62M | 9.92M | 9.38M | 12.54M | 12.29M |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 49.71M | 52.55M | 49.38M | 45.09M | 41.25M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 36.20M | 38.46M | 44.93M | 53.64M | 45.95M |
| Operating Income | -19.68M | -20.05M | -26.05M | -36.19M | -36.18M | -38.04M | -44.97M | -22.14M | -24.18M | 14.61M | -24.50M | -35.66M | -27.84M | -90.16M | -75.97M | -59.52M | -55.91M | -94.89M | -59.12M | -173.82M | -58.09M | -85.40M | -64.94M | -79.34M | -54.89M | -59.58M | 34.08M | -50.41M | -25.60M | -9.00M | -13.04M | -14.94M | -8.72M | - | - | 13.51M | 14.09M | 4.45M | -8.55M | -4.70M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 14.20M | 7.40M | 6.22M | -6.09M | -3.91M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.77M | 6.83M | 4.75M | 4.83M | 4.69M |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 6.11M | 247.00K | 1.16M | -11.23M | -8.93M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | 0 | - | 615.00K | 1.01M | 126.00K |
| Net Income | -19.48M | -19.86M | -25.80M | -35.78M | -36.31M | -37.86M | -44.54M | -21.52M | -23.13M | 15.52M | -23.42M | -34.07M | -26.05M | -60.05M | -72.42M | -58.17M | -54.59M | -94.48M | -60.75M | -175.75M | -59.96M | -87.00M | -69.58M | -83.04M | -59.54M | -63.51M | 29.45M | -54.10M | -26.88M | -11.17M | -14.49M | -17.98M | -8.58M | - | - | 6.11M | 247.00K | 540.00K | -12.24M | -9.05M |
| Diluted EPS | - | - | - | - | - | - | -1.15 | -0.53 | -0.49 | 0.31 | - | - | - | - | - | - | - | - | - | -1.28 | -0.42 | - | -0.45 | -0.51 | -0.34 | -0.35 | 0.15 | -0.29 | -0.15 | -0.06 | -0.08 | -0.09 | -0.04 | - | - | 0.03 | 0.00 | 0.00 | -0.05 | -0.03 |
| R&D Expense | 15.60M | - | 20.23M | 30.88M | 31.24M | - | 60.05M | 43.75M | 58.71M | - | 61.40M | 71.92M | 70.63M | - | 82.35M | 85.69M | 74.51M | - | 81.23M | 52.82M | 46.86M | - | 40.61M | 37.21M | 40.47M | 43.83M | 26.03M | 28.03M | 19.69M | 20.20M | 13.33M | 9.73M | 7.65M | 8.49M | - | 9.75M | 11.01M | 14.94M | - | 14.81M |
Profit & Loss (Annual)
Figures in USD.
| Metric | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | 0 | 0 | 1.53M | 181.23M | 207.74M | 335.00M | 295.31M | - | 292.48M | 194.62M | 160.18M | 236.20M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | 85.57M | 74.15M | 63.18M | 39.46M |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | 206.92M | 120.47M | 97.00M | 196.73M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | 271.76M | 166.55M | 147.42M | 173.24M |
| Operating Income | -8.52M | -15.93M | -37.94M | -61.51M | -136.46M | -76.67M | -178.16M | -286.29M | -376.44M | - | -64.85M | -46.08M | -50.41M | 23.50M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | -40.84M | -8.27M | -13.72M | 21.73M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | 15.69M | 6.03M | 18.18M | 24.18M |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | -94.23M | -51.92M | -69.41M | -3.72M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 1.62M |
| Net Income | -8.20M | -13.17M | -37.03M | -60.72M | -135.75M | -73.67M | -143.59M | -279.66M | -383.46M | - | -94.23M | -51.92M | -69.41M | -5.34M |
| Diluted EPS | - | - | - | - | - | - | - | -2.36 | -2.77 | - | -0.51 | -0.28 | -0.33 | -0.02 |
| R&D Expense | 5.63M | 8.90M | 23.26M | 43.02M | 115.78M | 230.89M | 291.01M | 322.97M | 218.49M | 147.85M | 129.99M | 63.08M | 37.65M | 62.36M |
Balance Sheet (Annual)
Figures in USD.
| Metric | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | - | - | 34.66M | 111.00M | 142.94M | 300.22M | 364.25M | 996.54M | 771.20M | 644.14M | - | 356.05M | 241.70M | 220.67M | 376.56M |
| Current Assets | - | - | - | - | - | - | - | - | - | - | - | 185.18M | 118.15M | 113.83M | 252.96M |
| Cash & Equivalents | 5.01M | 1.64M | 21.21M | 32.78M | 49.78M | 187.34M | 70.16M | 104.64M | 147.45M | 228.70M | - | 90.47M | 42.92M | 51.87M | 184.84M |
| Inventory | - | - | - | - | - | - | - | - | - | - | - | 21.57M | 15.69M | 16.24M | 15.61M |
| Receivables | - | - | - | - | - | - | - | - | - | - | - | 40.28M | 39.29M | 34.37M | 47.03M |
| Total Liabilities | - | - | 3.91M | 6.92M | 11.94M | 232.10M | 241.67M | 360.61M | 376.44M | 396.52M | - | 350.82M | 272.29M | 269.86M | 343.95M |
| Current Liabilities | - | - | 3.90M | 6.88M | 11.87M | 114.27M | 141.11M | 265.69M | 208.12M | 187.15M | - | 129.54M | 99.87M | 80.91M | 162.94M |
| Long Term Debt | - | - | - | - | - | - | - | - | 75.81M | 96.38M | - | 34.08M | 17.18M | 38.69M | 48.25M |
| Total Debt | - | - | - | - | - | - | - | - | - | - | - | 99.78M | 48.12M | 47.64M | 51.80M |
| Total Equity | -48.19M | -59.59M | -127.07M | 104.08M | 131.00M | 68.12M | 122.57M | 635.93M | 394.76M | 247.62M | - | 5.23M | -30.58M | -49.19M | 32.61M |
| Shares Outstanding | - | - | - | - | - | - | - | - | - | - | - | 184.14M | 194.58M | 224.85M | 265.42M |
Cash Flows (Annual)
Figures in USD.
| Metric | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | - | - | - | 57.91M | -56.16M | -97.49M | -257.44M | -110.39M | - | -73.15M | -23.38M | -40.66M | 67.99M |
| Investing Cash Flow | - | - | - | 12.71M | -177.26M | 36.59M | 211.18M | -40.00M | - | -114.00K | 0 | -33.00K | -7.93M |
| Financing Cash Flow | - | - | - | 66.95M | 116.24M | 96.56M | 88.97M | 231.72M | - | 14.60M | -25.21M | 49.66M | 72.93M |
| Capital Expenditure | -19.00K | -229.00K | -414.00K | -2.66M | -1.62M | -1.61M | -6.66M | -317.00K | -59.00K | -114.00K | - | -33.00K | -8.10M |
| Free Cash Flow | - | - | - | 55.24M | -57.78M | -99.10M | -264.10M | -110.70M | - | -73.27M | -23.38M | -40.69M | 59.89M |
| Net Change in Cash | - | - | - | - | - | - | - | - | - | -58.67M | -48.59M | 8.97M | 132.99M |
| Share Buybacks | - | 162.00K | - | - | - | - | - | - | - | - | - | - | - |
Ratios (Annual)
Figures in %.
| Metric | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | - | - | - | - | 70.7% | 61.9% | 60.6% | 83.3% |
| Operating Margin % | - | - | - | - | -8,889.9% | -42.3% | -85.8% | -85.5% | -127.5% | - | -22.2% | -23.7% | -31.5% | 9.9% |
| Net Margin % | - | - | - | - | -8,843.5% | -40.7% | -69.1% | -83.5% | -129.9% | - | -32.2% | -26.7% | -43.3% | -2.3% |
| ROE % | 13.8% | 10.4% | -35.6% | -46.3% | -199.3% | -60.1% | -22.6% | -70.8% | -154.9% | - | -1,801.6% | 169.8% | 141.1% | -16.4% |
| ROCE % | - | -51.8% | -36.4% | -46.9% | -73.4% | -34.4% | -24.4% | -50.8% | -82.4% | - | -28.6% | -32.5% | -36.1% | 11.0% |
Shareholding Pattern
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
Latest News
Recent headlines for AKBA
Akebia Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
CAMBRIDGE, Mass., July 02, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, granted 3 newly-hired employees options to…
Akebia Therapeutics, Inc. (AKBA) Strengthens Vafseo Patent Protection Through 2036
We recently compiled a list of the 12 Best Low-Priced Pharma Stocks to Buy Right Now. Akebia Therapeutics, Inc. (NASDAQ:AKBA) is one of the best low-priced pharma stocks on this list. TheFly reported on June 10 that AKBA strengthened the in…
U.S. Renal Care and Akebia Announce Interim Analysis of VOICE Trial Demonstrated Overwhelming Statistical Evidence of Improved Safety Outcomes for Patients Treated with Vafseo versus an ESA
Vafseo® demonstrated a clinically meaningful safety outcome benefit in U.S. patients with anemia due to CKD on dialysis utilizing TIW dosing regimen Primary Investigator to stop trial on recommendation from Independent Data Monitoring Commi…
Akebia Therapeutics Strengthens Vafseo® (vadadustat) Patent Portfolio
Additional Orange Book Listed Patent Secured and Composition of Matter Patent is Eligible for 5-Year ExtensionCAMBRIDGE, Mass., June 10, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with th…
Akebia Therapeutics Sees Vafseo Uptake Rising as Access and Pipeline Milestones Near
Akebia Therapeutics (NASDAQ:AKBA) outlined its commercial priorities for Vafseo, the expected evolution of reimbursement after the TDAPA period and several renal-disease pipeline programs during a fireside chat at the Jefferies 2026 Global …
Akebia Therapeutics to Present at the 2026 Jefferies Global Healthcare Conference
CAMBRIDGE, Mass., May 28, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today announced that Erik Ostrowski, Chief …
AKBA — Frequently Asked Questions
What is the current share price of Akebia Therapeutics, Inc. (AKBA)?
As of 2026-07-15 16:51 PDT, Akebia Therapeutics, Inc. (AKBA) trades at $1.38 on NasdaqCM. Its 52-week range is $0.87 to $4.01.
What is the market capitalisation of AKBA?
Akebia Therapeutics, Inc. (AKBA) has a market capitalisation of $370.20M on NasdaqCM.
What is the P/E ratio of AKBA?
AKBA trades at a trailing price-to-earnings (P/E) ratio of -17.25. The industry average P/E is 25.88. Its price-to-book (P/B) ratio is 9.06.
What is the return on equity (ROE) of AKBA?
AKBA has a return on equity (ROE) of -78.95%. Its return on capital employed (ROCE) is 9.58%.
Is AKBA a good stock to buy?
This page provides a data-driven analysis of Akebia Therapeutics, Inc. (AKBA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.