Akebia Therapeutics, Inc. AKBA R2KR3KPHARMA
Company Overview
Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. Its product portfolio includes Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent (DD) and non-dialysis dependent (NDD) patients; and Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD and the treatment of iron deficiency anemia in adult patients with NDD-CKD. The company is also developing AKB-9090, which is in Phase 2 clinical trial for treating cardiac surgery-related acute kidney injury and acute respiratory distress syndrome; and AKB-10108 for the treatment of retinopathy of prematurity in neonates. The company has license and collaboration agreements with Tanabe Pharma Corporation for the development and commercialization of Vafseo in Japan and other Asian countries; Vafseo License and Collaboration Agreements; CSL Vifor Agreements; Averoa License Agreement; License Agreement with Panion & BF Biotech, Inc.; Cyclerion Therapeutics License Agreement; and Q32 Asset Purchase Agreement. Akebia Therapeutics, Inc. was incorporated in 2007 and is headquartered in Waltham, Massachusetts.
Why Investors Should Care
Generates positive free cash flow, funding growth and shareholder returns internally.
Recent Developments
- Dec 2025 Revenue of $236.20M (+47.5% YoY); net profit $-5.34M.
- Trailing 12 Months Year-on-year growth — revenue -21.4%.
- 5-Year Trend Long-term compounding — revenue CAGR -6.8%.
Growth & Price Performance
Compounded Sales Growth
| 5 Years: | -6.75% |
| 1 Year: | -21.40% |
Stock Price Performance
| 1 Year: | -82.82% |
| 6 Months: | -60.36% |
| 3 Months: | -55.71% |
| 1 Month: | -38.31% |
Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.
- Price vs 50-DMABelow
- Price vs 200-DMABelow
- RSI (14)20.93 · Oversold
Auto-generated from price history and fundamentals; not investment advice.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth Charts
No fundamental data available for this stock.
Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.
PROS
- Generates positive free cash flow.
CONS
- Revenue declined at -6.8% CAGR over 5 years.
- Trading 82.8% below its 52-week high.
- In a downtrend (50-DMA below 200-DMA).
- RSI at 21 suggests oversold conditions.
* The pros and cons are auto-generated from financial metrics.
Valuation
Growth (CAGR)
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | AKBA Akebia Therapeutics, Inc. R2KR3KPHARMA | 0.57 | -4.75 | $157.95M | 0.00% | 11.00% | -109.38% | -6.75% | - |
| 2 | LLY Eli Lilly and Company SPXR3KPHARMA | 1,273.46 | 42.83 | $1.14T | 0.60% | - | 102.29% | 7.20% | 11.41% |
| 3 | JNJ Johnson & Johnson SPXR3KPHARMA | 263.81 | 30.60 | $635.76B | 1.98% | 14.88% | 25.74% | 2.43% | 4.76% |
| 4 | ABBV AbbVie Inc. SPXR3KPHARMA | 285.64 | 80.69 | $504.76B | 2.54% | 10.47% | -129.24% | 1.75% | -29.06% |
| 5 | UNH UnitedHealth Group Incorporated SPXR3KPHARMA | 418.09 | 26.85 | $375.28B | 2.47% | 9.74% | 14.15% | 10.40% | 5.43% |
| 6 | MRK Merck & Co., Inc. SPXR3KPHARMA | 145.27 | 116.22 | $358.41B | 2.31% | - | 6.96% | 5.64% | 10.01% |
| 7 | NVS Novartis AG PHARMA | 151.12 | 22.83 | $287.24B | 3.36% | 21.09% | 30.35% | 9.25% | 26.22% |
| 8 | AZN AstraZeneca PLC NDXPHARMA | 171.49 | 25.63 | $265.96B | 2.00% | 15.97% | 21.96% | 9.82% | 45.96% |
| 9 | TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA | 673.82 | 36.30 | $249.14B | 0.29% | 8.14% | 13.51% | 8.81% | 12.95% |
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios
Quarterly Results
Figures in USD.
| Metric | Dec 2015 | Mar 2016 | Jun 2016 | Sep 2016 | Dec 2016 | Mar 2017 | Jun 2017 | Sep 2017 | Dec 2017 | Mar 2018 | Jun 2018 | Sep 2018 | Dec 2018 | Mar 2019 | Jun 2019 | Sep 2019 | Dec 2019 | Mar 2020 | Jun 2020 | Sep 2020 | Dec 2020 | Mar 2021 | Jun 2021 | Sep 2021 | Mar 2022 | Jun 2022 | Sep 2022 | Mar 2023 | Jun 2023 | Sep 2023 | Mar 2024 | Jun 2024 | Sep 2024 | Dec 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 | Jun 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | 28.52M | 41.28M | - | 45.93M | 48.79M | 53.17M | - | 72.67M | 100.80M | 91.98M | - | 88.48M | 90.14M | 59.99M | - | 52.30M | 52.91M | 48.76M | 61.70M | 126.36M | 48.71M | 40.01M | 56.38M | 42.05M | 32.61M | 43.65M | - | - | 57.34M | 62.47M | 58.77M | 57.62M | 53.54M | 49.13M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.62M | 9.92M | 9.38M | 12.54M | 12.29M | - |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 49.71M | 52.55M | 49.38M | 45.09M | 41.25M | - |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 36.20M | 38.46M | 44.93M | 53.64M | 45.95M | - |
| Operating Income | -20.05M | -26.05M | -36.19M | -36.18M | -38.04M | -44.97M | -22.14M | -24.18M | 14.61M | -24.50M | -35.66M | -27.84M | -90.16M | -75.97M | -59.52M | -55.91M | -94.89M | -59.12M | -173.82M | -58.09M | -85.40M | -64.94M | -79.34M | -54.89M | -59.58M | 34.08M | -50.41M | -25.60M | -9.00M | -13.04M | -14.94M | -8.72M | - | - | 13.51M | 14.09M | 4.45M | -8.55M | -4.70M | -6.33M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 14.20M | 7.40M | 6.22M | -6.09M | -3.91M | - |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.77M | 6.83M | 4.75M | 4.83M | 4.69M | - |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 6.11M | 247.00K | 1.16M | -11.23M | -8.93M | - |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | 0 | - | 615.00K | 1.01M | 126.00K | - |
| Net Income | -19.86M | -25.80M | -35.78M | -36.31M | -37.86M | -44.54M | -21.52M | -23.13M | 15.52M | -23.42M | -34.07M | -26.05M | -60.05M | -72.42M | -58.17M | -54.59M | -94.48M | -60.75M | -175.75M | -59.96M | -87.00M | -69.58M | -83.04M | -59.54M | -63.51M | 29.45M | -54.10M | -26.88M | -11.17M | -14.49M | -17.98M | -8.58M | - | - | 6.11M | 247.00K | 540.00K | -12.24M | -9.05M | -8.91M |
| Diluted EPS | - | - | - | - | - | -1.15 | -0.53 | -0.49 | 0.31 | - | - | - | - | - | - | - | - | - | -1.28 | -0.42 | - | -0.45 | -0.51 | -0.34 | -0.35 | 0.15 | -0.29 | -0.15 | -0.06 | -0.08 | -0.09 | -0.04 | - | - | 0.03 | 0.00 | 0.00 | -0.05 | -0.03 | -0.03 |
| R&D Expense | - | 20.23M | 30.88M | 31.24M | - | 60.05M | 43.75M | 58.71M | - | 61.40M | 71.92M | 70.63M | - | 82.35M | 85.69M | 74.51M | - | 81.23M | 52.82M | 46.86M | - | 40.61M | 37.21M | 40.47M | 43.83M | 26.03M | 28.03M | 19.69M | 20.20M | 13.33M | 9.73M | 7.65M | 8.49M | - | 9.75M | 11.01M | 14.94M | - | 14.81M | 14.06M |
Profit & Loss (Annual)
Figures in USD.
| Metric | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | 0 | 0 | 1.53M | 181.23M | 207.74M | 335.00M | 295.31M | - | 292.48M | 194.62M | 160.18M | 236.20M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | 85.57M | 74.15M | 63.18M | 39.46M |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | 206.92M | 120.47M | 97.00M | 196.73M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | 271.76M | 166.55M | 147.42M | 173.24M |
| Operating Income | -8.52M | -15.93M | -37.94M | -61.51M | -136.46M | -76.67M | -178.16M | -286.29M | -376.44M | - | -64.85M | -46.08M | -50.41M | 23.50M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | -40.84M | -8.27M | -13.72M | 21.73M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | 15.69M | 6.03M | 18.18M | 24.18M |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | -94.23M | -51.92M | -69.41M | -3.72M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 1.62M |
| Net Income | -8.20M | -13.17M | -37.03M | -60.72M | -135.75M | -73.67M | -143.59M | -279.66M | -383.46M | - | -94.23M | -51.92M | -69.41M | -5.34M |
| Diluted EPS | - | - | - | - | - | - | - | -2.36 | -2.77 | - | -0.51 | -0.28 | -0.33 | -0.02 |
| R&D Expense | 5.63M | 8.90M | 23.26M | 43.02M | 115.78M | 230.89M | 291.01M | 322.97M | 218.49M | 147.85M | 129.99M | 63.08M | 37.65M | 62.36M |
Balance Sheet (Annual)
Figures in USD.
| Metric | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | - | - | 34.66M | 111.00M | 142.94M | 300.22M | 364.25M | 996.54M | 771.20M | 644.14M | - | 356.05M | 241.70M | 220.67M | 376.56M |
| Current Assets | - | - | - | - | - | - | - | - | - | - | - | 185.18M | 118.15M | 113.83M | 252.96M |
| Cash & Equivalents | 5.01M | 1.64M | 21.21M | 32.78M | 49.78M | 187.34M | 70.16M | 104.64M | 147.45M | 228.70M | - | 90.47M | 42.92M | 51.87M | 184.84M |
| Inventory | - | - | - | - | - | - | - | - | - | - | - | 21.57M | 15.69M | 16.24M | 15.61M |
| Receivables | - | - | - | - | - | - | - | - | - | - | - | 40.28M | 39.29M | 34.37M | 47.03M |
| Total Liabilities | - | - | 3.91M | 6.92M | 11.94M | 232.10M | 241.67M | 360.61M | 376.44M | 396.52M | - | 350.82M | 272.29M | 269.86M | 343.95M |
| Current Liabilities | - | - | 3.90M | 6.88M | 11.87M | 114.27M | 141.11M | 265.69M | 208.12M | 187.15M | - | 129.54M | 99.87M | 80.91M | 162.94M |
| Long Term Debt | - | - | - | - | - | - | - | - | 75.81M | 96.38M | - | 34.08M | 17.18M | 38.69M | 48.25M |
| Total Debt | - | - | - | - | - | - | - | - | - | - | - | 99.78M | 48.12M | 47.64M | 51.80M |
| Total Equity | -48.19M | -59.59M | -127.07M | 104.08M | 131.00M | 68.12M | 122.57M | 635.93M | 394.76M | 247.62M | - | 5.23M | -30.58M | -49.19M | 32.61M |
| Shares Outstanding | - | - | - | - | - | - | - | - | - | - | - | 184.14M | 194.58M | 224.85M | 265.42M |
Cash Flows (Annual)
Figures in USD.
| Metric | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | - | - | - | 57.91M | -56.16M | -97.49M | -257.44M | -110.39M | - | -73.15M | -23.38M | -40.66M | 67.99M |
| Investing Cash Flow | - | - | - | 12.71M | -177.26M | 36.59M | 211.18M | -40.00M | - | -114.00K | 0 | -33.00K | -7.93M |
| Financing Cash Flow | - | - | - | 66.95M | 116.24M | 96.56M | 88.97M | 231.72M | - | 14.60M | -25.21M | 49.66M | 72.93M |
| Capital Expenditure | -19.00K | -229.00K | -414.00K | -2.66M | -1.62M | -1.61M | -6.66M | -317.00K | -59.00K | -114.00K | - | -33.00K | -8.10M |
| Free Cash Flow | - | - | - | 55.24M | -57.78M | -99.10M | -264.10M | -110.70M | - | -73.27M | -23.38M | -40.69M | 59.89M |
| Net Change in Cash | - | - | - | - | - | - | - | - | - | -58.67M | -48.59M | 8.97M | 132.99M |
| Share Buybacks | - | 162.00K | - | - | - | - | - | - | - | - | - | - | - |
Ratios (Annual)
Figures in %.
| Metric | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | - | - | - | - | 70.7% | 61.9% | 60.6% | 83.3% |
| Operating Margin % | - | - | - | - | -8,889.9% | -42.3% | -85.8% | -85.5% | -127.5% | - | -22.2% | -23.7% | -31.5% | 9.9% |
| Net Margin % | - | - | - | - | -8,843.5% | -40.7% | -69.1% | -83.5% | -129.9% | - | -32.2% | -26.7% | -43.3% | -2.3% |
| ROE % | 13.8% | 10.4% | -35.6% | -46.3% | -199.3% | -60.1% | -22.6% | -70.8% | -154.9% | - | -1,801.6% | 169.8% | 141.1% | -16.4% |
| ROCE % | - | -51.8% | -36.4% | -46.9% | -73.4% | -34.4% | -24.4% | -50.8% | -82.4% | - | -28.6% | -32.5% | -36.1% | 11.0% |
Shareholding Pattern
Top Institutional Holders
| # | Holder | % Held | Shares | Value |
|---|---|---|---|---|
| 1 | Blackrock Inc. | 7.21% | 19.99M | $16.01M |
| 2 | Vanguard Capital Management LLC | 4.09% | 11.32M | $9.07M |
| 3 | AQR Capital Management, LLC | 3.30% | 9.15M | $7.33M |
| 4 | Geode Capital Management, LLC | 2.43% | 6.73M | $5.39M |
| 5 | State Street Corporation | 1.95% | 5.39M | $4.32M |
| 6 | Jacobs Levy Equity Management, Inc. | 1.54% | 4.27M | $3.42M |
| 7 | Acadian Asset Management. LLC | 1.45% | 4.00M | $3.21M |
| 8 | Goldman Sachs Group Inc | 1.33% | 3.69M | $2.96M |
| 9 | Millennium Management Llc | 1.15% | 3.20M | $2.56M |
| 10 | Vanguard Portfolio Management LLC | 0.91% | 2.53M | $2.03M |
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
Latest News
Recent headlines for AKBA
Akebia Therapeutics to Conduct Investor Meetings at the Virtual U.S. Bancorp I BTIG Kidney Health Forum
WALTHAM, Mass., Oct. 07, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today announced that John P. Butler, Chief E…
Akebia Therapeutics Announces Late-Breaking VOICE Trial Presentation and Posters on Akebia’s Rare Kidney Pipeline at ASN Kidney Week 2026
Additional poster presentations highlight Vafseo® (vadadustat) clinical and economic dataWALTHAM, Mass., Oct. 06, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the…
Akebia Therapeutics Announces First Patient Dosed in Phase 2 Basket Trial of Ebribafusp in Rare Complement-Mediated Kidney Diseases
Open-label Phase 2 trial evaluating ebribafusp for the treatment of IgA nephropathy, lupus nephritis and C3 glomerulopathy Initial data is expected in 2027 WALTHAM, Mass., Sept. 14, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasda…
Akebia Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
CAMBRIDGE, Mass., Sept. 01, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, granted one newly-hired employee options …
Akebia Therapeutics to Conduct Investor Meetings at the 2026 Wells Fargo Healthcare Conference in Boston
CAMBRIDGE, Mass., Sept. 01, 2026 (GLOBE NEWSWIRE) -- Akebia Therapeutics®, Inc. (Nasdaq: AKBA), a biopharmaceutical company with the purpose to better the lives of people impacted by kidney disease, today announced that John P. Butler, Chie…
Akebia Therapeutics Inc (AKBA) (Q2 2026) Earnings Call Highlights: Vafseo Surges 60% as VOICE ...
Akebia Therapeutics Inc (AKBA) reports strong Vafseo growth with over 10,500 patients, while navigating Erixia declines and planning strategic price adjustments for 2027.
AKBA — Frequently Asked Questions
What is the current share price of Akebia Therapeutics, Inc. (AKBA)?
As of 2026-10-23 16:27 PDT, Akebia Therapeutics, Inc. (AKBA) trades at $0.57 on NasdaqCM. Its 52-week range is $0.56 to $3.30.
What is the market capitalisation of AKBA?
Akebia Therapeutics, Inc. (AKBA) has a market capitalisation of $157.95M on NasdaqCM.
What is the P/E ratio of AKBA?
AKBA trades at a trailing price-to-earnings (P/E) ratio of -4.75. The industry average P/E is 25.45. Its price-to-book (P/B) ratio is 8.71.
What is the return on equity (ROE) of AKBA?
AKBA has a return on equity (ROE) of -109.38%. Its return on capital employed (ROCE) is 11.00%.
Is AKBA a good stock to buy?
This page provides a data-driven analysis of Akebia Therapeutics, Inc. (AKBA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.