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Acrivon Therapeutics, Inc. ACRV PHARMA

Healthcare · Biotechnology · United States
https://acrivon.com
Company Profile ↓
$2.10
+60.31% 1Y
Mkt Cap$89.99M
P/E-1.12
P/B0.98
52W High$3.01
52W Low$1.29
Book Value$2.02
EPS (TTM)$-1.88

Company Overview

Acrivon Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops oncology medicines for patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its generative phosphoproteomics platform. The company operates Acrivon Predictive Precision Proteomics (AP3), a precision medicine platform that enables the creation of drug specific proprietary OncoSignature companion diagnostics that are used to identify the patients to benefit from its drug candidates. Its lead clinical candidate is ACR-368, a selective small molecule inhibitor targeting CHK1 and CHK2 for the treatment of patients with endometrial and platinum-resistant ovarian cancer, and SCCs, such as SCCHN and anal cancer. The company is also developing ACR-2316, a dual WEE1 and PKMYT1 inhibitor small molecule candidate; and a preclinical stage AP3-and co-crystallography-based preclinical cell cycle program. The company was incorporated in 2018 and is based in Watertown, Massachusetts.

Growth & Price Performance

Stock Price Performance

1 Year:+60.31%
6 Months:+31.25%
3 Months:+48.94%
1 Month:+21.39%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 47% of range
$1.29 $3.01
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • Golden Cross2d ago
  • RSI (14)55.89 · Neutral
Price Performance
1M+21.39%
3M+48.94%
6M+31.25%
1Y+60.31%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Trading 30.2% below its 52-week high.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-1.12
Industry PE
24.83
Forward P/E
-1.25
PEG Ratio
-
Book Value
$2.02
Price to Book
0.98
P/S
-
EV/EBITDA
-0.03
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-73.75%
ROE
-64.63%
ROA
-38.02%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.49
EPS (TTM)
$-1.88

Balance Sheet & Liquidity

Debt/Equity
2.44
Quick Ratio
7.86
Current Ratio
7.99
Debt
$2.12M
Total Assets
$107.83M
Current Assets
$99.22M
Working Capital
$104.78M

Ownership

Promoter Holding
15.40%
Chg in Prom Hold
0.04%
FII / Inst Holding
50.34%
Chg in FII Hold
2.88%

Financial Snapshot

Enterprise Value
$89.99M
Total Revenue (TTM)
$0
EBITDA
$-76.88M
Free Cash Flow
$-39.82M
Operating Cash Flow
$-62.92M
Shares Outstanding
42.85M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 ACRV Acrivon Therapeutics, Inc. PHARMA 2.10 -1.12 $89.99M 0.00% -73.75% -64.63% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue -------------00000
Cost of Revenue ------------------
Gross Profit ------------------
Operating Expenses -------------21.66M22.65M19.69M20.12M19.90M
Operating Income ---2.67M-7.21M-5.92M-9.57M-14.39M-15.52M-16.14M-17.67M-21.44M-25.14M--21.66M-22.65M-19.69M-20.12M-19.90M
EBITDA --------------21.35M-22.31M-19.34M-19.75M-19.52M
Interest Expense ------------------
Pretax Income --------------19.68M-21.01M-18.23M-18.98M-19.04M
Tax Provision ------------------
Net Income -6.91M-2.55M-2.44M-7.22M-5.82M-9.20M-12.76M-13.91M-14.47M-16.49M-18.80M-22.44M--19.68M-21.01M-18.23M-18.98M-19.04M
Diluted EPS ---1.38-4.08-3.29-5.17-0.58-0.63-0.66-0.73-0.52-0.59-0.60-0.51-0.55-0.47--0.49
R&D Expense ------9.76M10.52M10.27M11.47M15.03M18.86M-15.41M16.18M13.65M-15.17M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -0000
Cost of Revenue -----
Gross Profit -----
Operating Expenses -32.66M67.10M89.20M84.11M
Operating Income --32.66M-67.10M-89.20M-84.11M
EBITDA --32.29M-66.57M-88.19M-82.76M
Interest Expense -----
Pretax Income --31.17M-60.39M-80.56M-77.91M
Tax Provision -----
Net Income --31.17M-60.39M-80.56M-77.91M
Diluted EPS --7.56-2.74-2.38-2.02
R&D Expense -23.95M46.02M63.99M59.99M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --181.23M138.26M196.59M129.72M
Current Assets --132.09M129.69M181.63M120.44M
Cash & Equivalents --29.52M36.02M39.82M41.50M
Inventory ------
Receivables ------
Total Liabilities --10.75M17.07M19.80M17.20M
Current Liabilities --6.52M13.30M17.21M15.66M
Long Term Debt ------
Total Debt --4.96M4.64M3.65M2.71M
Total Equity -8.41M-170.47M121.19M176.79M112.52M
Shares Outstanding --21.92M22.52M31.23M31.65M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow --30.12M-42.64M-65.67M-63.66M
Investing Cash Flow --141.68M50.72M-51.77M66.10M
Financing Cash Flow -101.71M-1.55M121.03M-749.00K
Capital Expenditure --2.17M-1.29M-2.77M-1.67M
Free Cash Flow --32.28M-43.93M-68.44M-65.33M
Net Change in Cash --70.08M6.52M3.59M1.69M

Ratios (Annual)

Figures in %.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----
Operating Margin % -----
Net Margin % -----
ROE % --18.3%-49.8%-45.6%-69.2%
ROCE % --18.7%-53.7%-49.7%-73.7%

Shareholding Pattern

Insiders
15.40%
Institutions
50.34%
Public Float
59.50%

Top Institutional Holders

#Holder% HeldSharesValue
1 RA Capital Management, L.P. 28.54% 12.23M $22.62M
2 Sands Capital Alternatives, LLC 5.34% 2.29M $4.24M
3 Acadian Asset Management. LLC 2.72% 1.17M $2.16M
4 Vanguard Capital Management LLC 2.22% 952.01K $1.76M
5 Wellington Management Group, LLP 2.07% 888.13K $1.64M
6 Renaissance Technologies, LLC 1.77% 758.86K $1.40M
7 Two Sigma Investments, LP 1.50% 641.50K $1.19M
8 Marshall Wace LLP 1.24% 531.86K $983.93K
9 Bridgeway Capital Management, LLC 0.88% 378.90K $700.97K
10 Geode Capital Management, LLC 0.62% 265.24K $490.69K

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for ACRV

Yahoo Finance hu, 03 Sep 2026

Acrivon Therapeutics, Inc. (ACRV) Just Flashed Golden Cross Signal: Do You Buy?

When a stock experiences a golden cross technical event, good things could be on the horizon. How should investors react?

Yahoo Finance Wed, 02 Sep 2026

Acrivon Therapeutics to Present at the 2026 Cantor Global Healthcare Conference

WATERTOWN, Mass., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Acrivon Therapeutics, Inc. (“Acrivon” or “Acrivon Therapeutics”) (Nasdaq: ACRV), a clinical stage biotechnology company discovering and developing precision medicines utilizing its propri…

Yahoo Finance Mon, 31 Aug 2026

Acrivon Therapeutics Appoints Michaela Levin, Ph.D., as Chief Business Officer

Experienced biotechnology executive brings an extensive track record in business development, strategic transactions, licensing and corporate strategyWATERTOWN, Mass., Aug. 31, 2026 (GLOBE NEWSWIRE) -- Acrivon Therapeutics, Inc. (“Acrivon” …

Yahoo Finance Mon, 24 Aug 2026

Here's Why Acrivon Therapeutics, Inc. (ACRV) is a Great Momentum Stock to Buy

Does Acrivon Therapeutics, Inc. (ACRV) have what it takes to be a top stock pick for momentum investors? Let's find out.

Yahoo Finance ue, 21 Jul 2026

Acrivon to Highlight the Power of its AP3 Platform for Streamlined, Pathway-Based Drug Discovery and Development with Oral and Poster Presentations at AACR D3 Conference

Presentations feature mechanistic data on ACR-2316, a potential first-in-class, clinical WEE1/PKMYT1 inhibitor, rationally designed with AP3 for potent single agent activity and superior therapeutic index Early clinical responses, including…

Yahoo Finance hu, 21 May 2026

Acrivon Therapeutics to Present at TD Cowen’s 7th Annual Oncology Innovation Summit

WATERTOWN, Mass., May 21, 2026 (GLOBE NEWSWIRE) -- Acrivon Therapeutics, Inc. (“Acrivon” or “Acrivon Therapeutics”) (Nasdaq: ACRV), a clinical stage biotechnology company discovering and developing precision medicines utilizing its propriet…

ACRV — Frequently Asked Questions

What is the current share price of Acrivon Therapeutics, Inc. (ACRV)?

As of 2026-09-19 21:16 PDT, Acrivon Therapeutics, Inc. (ACRV) trades at $2.10 on NasdaqGM. Its 52-week range is $1.29 to $3.01.

What is the market capitalisation of ACRV?

Acrivon Therapeutics, Inc. (ACRV) has a market capitalisation of $89.99M on NasdaqGM.

What is the P/E ratio of ACRV?

ACRV trades at a trailing price-to-earnings (P/E) ratio of -1.12. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 0.98.

What is the return on equity (ROE) of ACRV?

ACRV has a return on equity (ROE) of -64.63%. Its return on capital employed (ROCE) is -73.75%.

Is ACRV a good stock to buy?

This page provides a data-driven analysis of Acrivon Therapeutics, Inc. (ACRV), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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