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$10.04
+25.19% 1Y
Mkt Cap$909.26M
P/E-4.11
P/B13.48
52W High$10.77
52W Low$3.45
Book Value$0.55
EPS (TTM)$-2.44

Company Overview

Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States. Its product candidates are Avutometinib, which is an orally administered, small molecule dual RAF/MEK inhibitor developed to block MEK kinase activity and the compensatory reactivation of MEK by upstream RAF, thereby targeting the RAS/MAPK signaling pathway that is commonly activated in various cancers; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine kinase for various solid tumors. The company is involved in clinical studies, including RAMP 301, a randomized global confirmatory trial to evaluate the combination of Avutometinib and Defactinib for the treatment of patients with recurrent low-grade serous ovarian cancer; RAMP 201, an adaptive two-part multicenter, parallel cohort, randomized open label trial to evaluate the efficacy and safety of Avutometinib and in combination with Defactinib; and FRAME, an investigation of Avutometinib and Defactinib in patients with KRAS mutant cancers and subsequent analyses; and RAMP 205. It has license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacture of products containing Avutometinib; and Pfizer Inc. to research, develop, manufacture, and commercialize products containing Pfizer's inhibitors of FAK for therapeutic, diagnostic, and prophylactic uses in humans. In addition, it has a clinical collaboration agreement with Amgen, Inc. to evaluate the combination of Avutometinib with Amgen's KRAS-G12C inhibitor LUMAKRAS, which in Phase 1/2 trial entitled RAMP 203; VS-7375, and VS-7375-101 is a discovery and development collaboration with GenFleet Therapeutics to advance new programs targeting RAS pathway-driven cancers; and AVMAPKI, FAKZYNJA, CO-PACK, is an avutometinib capsules, and defactinib tablets. The company was incorporated in 2010 and is headquartered in Needham, Massachusetts.

Recent Developments

  • Dec 2025 Revenue of $30.91M (+209.1% YoY); net profit $-209.47M.
  • Trailing 12 Months Year-on-year growth — revenue +1775.4%.
  • 5-Year Trend Long-term compounding — revenue CAGR 2.1%.

Growth & Price Performance

Compounded Sales Growth

5 Years:2.11%
1 Year:1,775.40%

Stock Price Performance

1 Year:+25.19%
6 Months:+69.88%
3 Months:+65.13%
1 Month:+28.72%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 90% of range
$3.45 $10.77
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)67.22 · Neutral
Price Performance
1M+28.72%
3M+65.13%
6M+69.88%
1Y+25.19%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-4.11
Industry PE
25.45
Forward P/E
-13.39
PEG Ratio
-
Book Value
$0.55
Price to Book
13.48
P/S
7.70
EV/EBITDA
-3.92
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
2.11%
Profit 5Y
-
Revenue (YoY)
1,775.40%
Earnings (YoY)
-

Profitability & Returns

ROCE
-97.68%
ROE
-
ROA
-49.59%
Profit Margin
-
Op Margin
-81.62%
Gross Margin
87.64%
EPS (Latest Qtr)
$-0.35
EPS (TTM)
$-2.44

Balance Sheet & Liquidity

Debt/Equity
1.69
Quick Ratio
2.12
Current Ratio
2.25
Debt
$84.33M
Total Assets
$206.51M
Current Assets
$202.90M
Working Capital
$151.15M

Ownership

Promoter Holding
1.09%
Chg in Prom Hold
0.07%
FII / Inst Holding
110.94%
Chg in FII Hold
0.02%

Financial Snapshot

Enterprise Value
$909.26M
Total Revenue (TTM)
$87.53M
EBITDA
$-158.65M
Free Cash Flow
$-103.43M
Operating Cash Flow
$-162.20M
Shares Outstanding
90.56M
Gross Margin
87.64%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 VSTM Verastem, Inc. R2KR3KPHARMA 10.04 -4.11 $909.26M 0.00% -97.68% - 2.11% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,273.46 42.83 $1.14T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 263.81 30.60 $635.76B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 285.64 80.69 $504.76B 2.54% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 418.09 26.85 $375.28B 2.47% 9.74% 14.15% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPXR3KPHARMA 145.27 116.22 $358.41B 2.31% - 6.96% 5.64% 10.01%
7 NVS Novartis AG PHARMA 151.12 22.83 $287.24B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 171.49 25.63 $265.96B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 673.82 36.30 $249.14B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue -----------10.00M15.51M1.21M1.67M3.14M9.03M3.62M5.06M4.31M78.65M506.00K1.01M500.00K2.00K2.60M------10.00M-02.14M11.24M17.54M18.67M-
Cost of Revenue ----------------------------------0446.00K1.96M2.89M3.05M-
Gross Profit ----------------------------------01.69M9.28M14.64M15.62M-
Operating Expenses ----------------------------------44.17M45.45M50.00M56.12M60.52M-
Operating Income -15.53M-11.96M-8.43M-8.71M-8.06M-11.80M-13.15M-13.47M-23.14M-18.05M-20.76M-18.19M-21.57M-34.26M-34.67M-38.28M-26.10M-33.29M-26.36M-21.26M15.02M-16.75M-14.11M-15.94M-14.85M-16.98M-21.40M-17.71M-19.34M-20.29M-21.31M-28.06M-18.28M-37.03M-44.17M-43.76M-40.72M-41.48M-44.90M-32.71M
EBITDA -----------------------------------51.90M-25.59M-97.91M-32.20M-35.93M-
Interest Expense ----------------------------------192.00K212.00K319.00K415.00K382.00K-
Pretax Income -----------------------------------52.10M-25.93M-98.52M-32.92M-36.59M-
Tax Provision ----------------------------------------
Net Income -15.45M-11.86M-8.29M-8.57M-7.92M-11.65M-13.01M-13.44M-23.13M-18.23M-21.05M-18.37M-21.67M-11.35M-38.10M-42.19M-30.14M-38.77M-37.99M-23.01M13.14M-19.86M-15.03M-16.90M-22.79M-16.96M-21.95M-18.09M-15.71M-24.28M-20.00M-33.86M-8.26M-23.97M-52.10M-25.93M-98.52M-32.92M-36.59M-34.67M
Diluted EPS -----------0.41-0.30-0.29-0.37-0.52-0.57-0.41-0.51-0.35-0.140.08-0.12-0.09-0.10-0.13-0.09-0.12-0.09-0.08-1.37-0.75-1.26-0.31-0.60-0.96-0.62-1.35--0.46-0.35
R&D Expense 11.30M7.69M4.18M4.49M4.22M6.89M8.38M9.04M17.74M11.25M10.93M12.38M11.57M8.76M9.76M11.35M12.22M12.46M10.92M9.34M10.96M10.15M8.90M9.73M9.32M13.64M14.89M11.29M12.02M12.89M13.95M17.71M18.06M24.75M29.15M24.79M28.99M-38.22M41.34M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -------26.72M17.46M88.52M2.05M2.60M010.00M30.91M
Cost of Revenue -----------0005.30M
Gross Profit -----------2.60M010.00M25.62M
Operating Expenses -----------75.53M92.08M124.96M195.75M
Operating Income -13.70M-32.23M-41.40M-53.61M-58.20M-37.00M-67.80M-94.78M-132.34M-49.36M-61.41M-72.94M-92.08M-114.96M-170.13M
EBITDA ------------71.56M-83.17M-125.86M-207.60M
Interest Expense -----------2.14M4.14M4.56M1.14M
Pretax Income ------------73.81M-87.37M-130.45M-209.47M
Tax Provision -----------00185.00K0
Net Income -13.68M-31.98M-41.20M-53.37M-57.87M-36.44M-67.80M-72.43M-149.21M-67.73M-71.20M-73.81M-87.37M-130.64M-209.47M
Diluted EPS ------0.99-1.76-1.37-2.00-0.44-4.90-4.57-3.96-3.66-3.02
R&D Expense 9.88M21.71M25.93M35.45M40.56M19.78M46.42M43.65M45.78M41.38M39.35M50.56M61.36M81.33M114.60M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -59.04M92.92M125.26M98.65M113.09M83.63M89.79M277.24M145.05M154.35M-95.05M149.72M101.54M246.44M
Current Assets ------------92.87M143.68M94.96M223.41M
Cash & Equivalents 3.58M33.90M10.10M18.89M33.90M24.87M32.35M82.18M129.87M43.51M67.78M-74.93M77.91M88.82M204.99M
Inventory --------------01.83M
Receivables -----------516.00K31.00K0200.00K-
Total Liabilities ------11.33M32.11M152.94M137.87M39.08M-47.66M92.34M130.43M189.25M
Current Liabilities -3.15M2.40M7.80M9.20M10.11M10.99M17.13M37.08M29.89M17.09M-21.66M26.38M30.97M72.27M
Long Term Debt -------14.83M----24.53M40.09M40.72M81.33M
Total Debt ------------27.07M41.56M42.25M87.17M
Total Equity -687.00K-12.77M90.47M117.45M88.77M102.47M72.30M57.68M124.30M7.17M115.27M-47.39M57.37M-28.89M57.20M
Shares Outstanding ------------16.71M25.28M44.78M77.74M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -----45.56M-29.48M-57.31M-74.52M-138.52M-33.51M--63.67M-86.46M-104.77M-137.51M
Investing Cash Flow -----27.06M36.93M43.95M-138.38M89.61M-47.36M-66.19M-44.45M59.97M-9.62M
Financing Cash Flow ----63.59M-5.00K63.18M261.16M-2.44M69.63M-51.78M134.19M54.78M263.31M
Capital Expenditure -785.00K-310.00K-56.00K-2.43M-211.00K-39.00K--1.51M-7.00K-33.00K-196.00K---28.00K-9.62M
Free Cash Flow -----45.77M-29.52M--76.02M-138.53M-33.54M--63.67M-86.46M-104.80M-147.13M
Net Change in Cash -----------54.30M3.29M9.98M116.17M

Ratios (Annual)

Figures in %.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----------100.0%-100.0%82.9%
Operating Margin % --------354.8%-758.1%-55.8%-2,991.2%-2,809.6%--1,149.6%-550.3%
Net Margin % --------271.1%-854.8%-76.5%-3,468.1%-2,843.3%--1,306.4%-677.6%
ROE % 107.2%-35.4%-35.1%-60.1%-56.5%-50.4%-117.5%-58.3%-2,079.9%-58.8%--155.8%-152.3%452.1%-366.2%
ROCE % -24.5%-35.6%-35.2%-59.9%-56.5%-50.9%-93.3%-39.5%-114.9%-36.0%--99.4%-74.7%-162.9%-97.7%

Shareholding Pattern

Insiders
1.09%
Institutions
110.94%
Public Float
112.16%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 10.15% 9.19M $77.03M
2 Armistice Capital, LLC 7.76% 7.02M $58.86M
3 RTW Investments LP 7.33% 6.64M $55.61M
4 Deep Track Capital, Lp 6.34% 5.74M $48.11M
5 State Street Corporation 5.67% 5.13M $43.02M
6 Rosalind Advisors, Inc. 4.40% 3.99M $33.41M
7 Vanguard Capital Management LLC 4.25% 3.85M $32.28M
8 Nantahala Capital Management, LLC 3.96% 3.58M $30.04M
9 Stonepine Capital Management, LLC 3.70% 3.35M $28.07M
10 Vanguard Portfolio Management LLC 3.61% 3.27M $27.38M

Analyst View

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Latest News

Recent headlines for VSTM

Google News hu, 22 Oct 2026

VSTM Stock Clocks Best Day In 11 Months After Positive Cancer Drug Trial Update And Multiple Price-Target Hikes - Stocktwits

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Google News hu, 15 Oct 2026

Verastem (VSTM) Shares Jumped On Trial Data And Funding, Is The Stock Still Cheap? - Yahoo Finance

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Google News Fri, 23 Oct 2026

How Trial Data At Verastem (VSTM) Has Changed Its Investment Story - Simply Wall Street

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Google News hu, 22 Oct 2026

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Google News hu, 22 Oct 2026

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VSTM — Frequently Asked Questions

What is the current share price of Verastem, Inc. (VSTM)?

As of 2026-10-23 16:27 PDT, Verastem, Inc. (VSTM) trades at $10.04 on NasdaqCM. Its 52-week range is $3.45 to $10.77.

What is the market capitalisation of VSTM?

Verastem, Inc. (VSTM) has a market capitalisation of $909.26M on NasdaqCM.

What is the P/E ratio of VSTM?

VSTM trades at a trailing price-to-earnings (P/E) ratio of -4.11. The industry average P/E is 25.45. Its price-to-book (P/B) ratio is 13.48.

Is VSTM a good stock to buy?

This page provides a data-driven analysis of Verastem, Inc. (VSTM), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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