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Simulations Plus, Inc. SLP R2KR3KPHARMA

Healthcare · Health Information Services · United States
https://www.simulations-plus.com
Company Profile ↓
$18.43
+26.84% 1Y
Mkt Cap$372.74M
P/E46.08
P/B2.66
52W High$20.84
52W Low$11.36
Book Value$6.88
EPS (TTM)$0.40

Company Overview

Simulations Plus, Inc. develops drug discovery and development software for modeling and simulation, and prediction of molecular properties utilizing artificial intelligence and machine learning based technology worldwide. It operates through Software and Services segments. The company offers GastroPlus, which predicts absorption, biopharmaceutics, pharmacokinetics, and pharmacodynamics in humans and animals; and DDDPlus and MembranePlus simulation products. It also provides products based on mechanistic and mathematical models, such as DILIsym, NAFLDsym, ILDsym, IPFsym, RENAsym, MITOsym, OBESITYsym, and Thales products. In addition, the company offers Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) predictor for chemistry-based computer program that takes molecular structures as inputs and predicts their properties; and MedChem Designer, as well as MonolixSuite products for modeling and simulation that allows for population analyses, rapid clinical trial data analyses, and regulatory submissions. Further, it provides clinical-pharmacology-based consulting services, which includes population pharmacokinetic and pharmacodynamic modeling, exposure-response analyses, clinical trial simulations, data programming, and technical writing services in support of regulatory submissions; and early drug discovery services. Additionally, the company offers creative and insightful consulting services to support its quantitative systems pharmacology and other modeling systems. The company serves pharmaceutical, biotechnology, agrochemical, cosmetics, and food industry companies, as well as academic and regulatory agencies. Simulations Plus, Inc. was incorporated in 1996 and is headquartered in Research Triangle Park, North Carolina.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 13.7% CAGR over the past five years.

Healthy Margins

Operating margin of 22.8% supports profitability.

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.35.

Positive Free Cash Flow

Generates positive free cash flow, funding growth and shareholder returns internally.

Recent Developments

  • Aug 2025 Revenue of $79.18M (+13.1% YoY); net profit $-64.72M.
  • Trailing 12 Months Year-on-year growth — revenue +7.5%, earnings -750.2%.
  • 5-Year Trend Long-term compounding — revenue CAGR 13.7%, profit CAGR -206.1%.

Growth & Price Performance

Compounded Sales Growth

5 Years:13.67%
1 Year:7.50%

Compounded Profit Growth

5 Years:-206.15%
1 Year:-750.17%

Stock Price Performance

1 Year:+26.84%
6 Months:+50.82%
3 Months:+16.06%
1 Month:+0.49%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 75% of range
$11.36 $20.84
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)64.14 · Neutral
Price Performance
1M+0.49%
3M+16.06%
6M+50.82%
1Y+26.84%
Valuation vs Sector

P/E of 46.08 is above the sector median of 25.17 — pricier than peers.

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 13.7% over 5 years.
  • Generates positive free cash flow.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Earnings shrank at -206.1% CAGR over 5 years.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
46.08
Industry PE
25.17
Forward P/E
20.88
PEG Ratio
9.88
Book Value
$6.88
Price to Book
2.66
P/S
4.52
EV/EBITDA
21.38
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
13.67%
Profit 5Y
-206.15%
Revenue (YoY)
7.50%
Earnings (YoY)
-750.17%

Profitability & Returns

ROCE
5.18%
ROE
6.17%
ROA
5.48%
Profit Margin
9.88%
Op Margin
22.84%
Gross Margin
63.38%
EPS (Latest Qtr)
$0.18
EPS (TTM)
$0.40

Balance Sheet & Liquidity

Debt/Equity
0.35
Quick Ratio
5.31
Current Ratio
5.54
Debt
$487.00K
Total Assets
$152.98M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
16.91%
Chg in Prom Hold
-0.00%
FII / Inst Holding
79.43%
Chg in FII Hold
0.63%

Financial Snapshot

Enterprise Value
$372.74M
Total Revenue (TTM)
$82.06M
EBITDA
$15.02M
Free Cash Flow
$18.41M
Operating Cash Flow
$24.94M
Shares Outstanding
20.22M
Gross Margin
63.38%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 SLP Simulations Plus, Inc. R2KR3KPHARMA 18.43 46.08 $372.74M 0.00% 5.18% 6.17% 13.67% -206.15%
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric May 2015Nov 2015Feb 2016May 2016Aug 2016Nov 2016Feb 2017May 2017Aug 2017Nov 2017Feb 2018May 2018Aug 2018Nov 2018Feb 2019May 2019Aug 2019Nov 2019Feb 2020May 2020Aug 2020Nov 2020Feb 2021May 2021Aug 2021Nov 2021Feb 2022May 2022Nov 2022Feb 2023May 2023Nov 2023Feb 2024May 2024Nov 2024Feb 2025May 2025Nov 2025Feb 2026May 2026
Revenue --------------8.47M9.94M--10.35M12.30M----------16.23M14.50M18.30M18.54M18.92M22.43M20.36M18.42M24.29M21.89M
Gross Profit 4.81M3.75M3.90M4.82M2.90M4.08M4.15M5.30M4.29M5.33M5.24M6.53M4.57M5.34M6.26M7.61M5.74M6.76M7.68M9.63M6.87M8.27M10.24M10.31M7.06M9.66M11.97M12.40M9.29M13.13M13.27M9.85M13.22M13.26M10.22M13.13M13.03M10.89M16.14M15.13M
Operating Income 2.85M1.73M1.72M2.79M-1.93M1.79M3.10M-2.56M2.42M3.42M-2.09M2.73M3.88M-2.72M2.83M3.86M-3.05M3.49M4.54M-3.79M5.48M4.95M878.00K4.03M4.10M960.00K4.44M1.88M126.00K2.71M-74.23M713.00K5.63M4.50M
Net Income 1.85M1.11M1.15M1.91M789.00K1.36M1.20M2.08M1.15M1.72M3.48M2.41M1.34M1.54M2.10M2.89M2.06M2.06M2.15M2.94M2.19M2.48M3.21M3.79M305.00K3.03M4.41M4.09M1.25M4.17M4.01M1.95M4.03M3.14M206.00K3.07M-67.32M676.00K4.54M3.58M
Diluted EPS 0.110.060.070.110.060.080.070.120.060.100.190.130.070.090.120.160.110.110.120.160.110.120.150.180.010.150.210.200.060.200.200.100.200.150.010.15-3.350.030.220.18
R&D Expense 348.29K351.31K461.39K348.43K-290.30K408.54K253.80K-360.82K484.33K508.36K-529.64K724.03K643.25K-526.00K748.00K752.00K-809.00K1.29M670.00K-882.00K902.00K655.00K1.17M1.32M945.00K1.22M1.31M1.30M1.85M2.14M1.22M2.98M3.47M3.41M

Profit & Loss (Annual)

Figures in USD.

Metric Aug 2012Aug 2013Aug 2014Aug 2015Aug 2016Aug 2017Aug 2018Aug 2019Aug 2020Aug 2021Aug 2022Aug 2023Aug 2024Aug 2025
Revenue 9.45K10.07M11.46M18.31M19.97M24.14M29.67M33.97M41.59M-53.91M59.58M70.01M79.18M
Cost of Revenue ----------10.82M11.63M26.86M32.96M
Gross Profit 7.94M8.42M9.83M13.92M15.37M17.83M21.67M24.94M30.94M-43.08M47.95M43.15M46.22M
Operating Expenses ----------28.17M38.72M37.02M39.73M
Operating Income 3.61M4.07M4.44M5.86M7.23M8.26M10.30M10.65M11.61M-14.91M9.22M6.13M6.49M
EBITDA ----------18.48M13.06M11.80M14.70M
Interest Expense ---------22.00K00--
Pretax Income ----------15.12M11.70M12.41M-69.38M
Tax Provision ----------2.63M1.73M2.46M-4.66M
Net Income 3.03M2.89M3.03M3.84M4.95M5.79M8.93M8.58M9.33M-12.48M9.96M9.95M-64.72M
Diluted EPS 0.190.180.180.230.290.330.500.480.50-0.600.490.49-3.22
R&D Expense 947.56K802.37K952.77K1.33M1.45M1.37M1.79M2.50M2.98M4.05M3.21M4.50M5.75M6.88M

Balance Sheet (Annual)

Figures in USD.

Metric Aug 2011Aug 2012Aug 2013Aug 2014Aug 2015Aug 2016Aug 2017Aug 2018Aug 2019Aug 2020Aug 2021Aug 2022Aug 2023Aug 2024Aug 2025
Total Assets -17.35M16.06M20.98M27.34M27.81M38.51M43.28M45.20M168.42M179.98M188.38M186.10M196.64M131.94M
Total Equity 14.04M15.14M14.24M15.44M19.53M22.73M25.80M31.92M37.68M156.03M165.78M178.25M170.03M182.43M124.80M
Cash & Equivalents 10.18M12.70M10.18M8.61M8.55M8.03M6.22M9.40M11.43M49.21M36.98M51.57M57.52M10.31M30.85M
Long Term Debt ------5.74M3.33M-------
Total Liabilities -2.20M1.82M5.55M7.81M5.08M12.71M11.36M7.52M12.39M14.20M10.13M16.07M14.21M7.13M
Current Liabilities -1.42M626.31K1.39M3.61M2.13M2.04M4.83M4.78M5.51M11.57M7.74M11.99M12.07M6.72M

Cash Flows (Annual)

Figures in USD.

Metric Aug 2012Aug 2013Aug 2014Aug 2015Aug 2016Aug 2017Aug 2018Aug 2019Aug 2020Aug 2021Aug 2022Aug 2023Aug 2024Aug 2025
Operating Cash Flow 3.78M2.56M-7.14M5.42M6.88M9.29M11.64M10.91M19.20M17.90M21.86M13.32M18.13M
Investing Cash Flow 839.49K-1.18M--3.13M-1.95M-4.36M-2.33M-1.96M-75.50M-26.74M4.30M7.37M-53.97M3.56M
Financing Cash Flow ----4.07M-3.98M-4.34M-3.77M-7.65M102.37M-4.68M-7.62M-23.27M-6.57M-1.15M
Capital Expenditure -106.83K-53.15K-24.49K-71.37K-39.12K-175.96K-183.29K-138.00K-231.00K-1.63M-819.00K-453.00K-566.00K-713.00K
Free Cash Flow 3.68M2.51M-7.06M5.38M6.70M9.10M11.50M10.68M17.58M17.08M21.40M12.75M17.41M
Share Buybacks ---------0020.00M00
Dividends Paid 2.38M4.00M3.08M3.38M3.41M3.45M4.16M4.20M4.25M4.81M4.85M4.81M4.80M0

Ratios (Annual)

Figures in %.

Metric Aug 2012Aug 2013Aug 2014Aug 2015Aug 2016Aug 2017Aug 2018Aug 2019Aug 2020Aug 2021Aug 2022Aug 2023Aug 2024Aug 2025
Gross Margin % 84,013.8%83.6%85.8%76.0%77.0%73.9%73.1%73.4%74.4%-79.9%80.5%61.6%58.4%
Operating Margin % 38,225.1%40.4%38.7%32.0%36.2%34.2%34.7%31.3%27.9%-27.7%15.5%8.8%8.2%
Net Margin % 32,044.5%28.7%26.4%21.0%24.8%24.0%30.1%25.3%22.4%-23.2%16.7%14.2%-81.7%
ROE % 20.0%20.3%19.6%19.7%21.8%22.4%28.0%22.8%6.0%-7.0%5.9%5.5%-51.9%
ROCE % 22.7%26.4%22.7%24.7%28.2%22.7%26.8%26.3%7.1%-8.3%5.3%3.3%5.2%

Shareholding Pattern

Insiders
16.91%
Institutions
79.43%
Public Float
95.60%

Top Institutional Holders

#Holder% HeldSharesValue
1 First Light Asset Management, LLC 13.81% 2.79M $51.36M
2 Blackrock Inc. 7.43% 1.50M $27.62M
3 First Eagle Investment Management, LLC 5.29% 1.07M $19.69M
4 Vanguard Capital Management LLC 3.67% 741.47K $13.64M
5 Kennedy Capital Management, LLC 2.67% 539.07K $9.91M
6 Tributary Capital Management, LLC 2.66% 538.25K $9.90M
7 Geode Capital Management, LLC 2.18% 440.37K $8.10M
8 Marshall Wace LLP 2.03% 410.54K $7.55M
9 State Street Corporation 1.89% 382.54K $7.03M
10 JPMORGAN CHASE & CO 1.61% 326.08K $6.00M

Analyst View

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Latest News

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SLP — Frequently Asked Questions

What is the current share price of Simulations Plus, Inc. (SLP)?

As of 2026-09-07 16:24 PDT, Simulations Plus, Inc. (SLP) trades at $18.43 on NasdaqGS. Its 52-week range is $11.36 to $20.84.

What is the market capitalisation of SLP?

Simulations Plus, Inc. (SLP) has a market capitalisation of $372.74M on NasdaqGS.

What is the P/E ratio of SLP?

SLP trades at a trailing price-to-earnings (P/E) ratio of 46.08. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 2.66.

What is the return on equity (ROE) of SLP?

SLP has a return on equity (ROE) of 6.17%. Its return on capital employed (ROCE) is 5.18%.

Is SLP a good stock to buy?

This page provides a data-driven analysis of Simulations Plus, Inc. (SLP), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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