Simulations Plus, Inc. SLP R2K
Simulations Plus, Inc. develops drug discovery and development software for modeling and simulation, and prediction of molecular properties utilizing artificial intelligence and machine learning based technology worldwide. It operates through Software and Services segments. The company offers GastroPlus, which predicts absorption, biopharmaceutics, pharmacokinetics, and pharmacodynamics in humans and animals; and DDDPlus and MembranePlus simulation products. It also provides products based on mechanistic and mathematical models, such as DILIsym, NAFLDsym, ILDsym, IPFsym, RENAsym, MITOsym, OBESITYsym, and Thales products. In addition, the company offers Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) predictor for chemistry-based computer program that takes molecular structures as inputs and predicts their properties; and MedChem Designer, as well as MonolixSuite products for modeling and simulation that allows for population analyses, rapid clinical trial data analyses, and regulatory submissions. Further, it provides clinical-pharmacology-based consulting services, which includes population pharmacokinetic and pharmacodynamic modeling, exposure-response analyses, clinical trial simulations, data programming, and technical writing services in support of regulatory submissions; and early drug discovery services. Additionally, the company offers creative and insightful consulting services to support its quantitative systems pharmacology and other modeling systems. The company serves pharmaceutical, biotechnology, agrochemical, cosmetics, and food industry companies, as well as academic and regulatory agencies. Simulations Plus, Inc. was incorporated in 1996 and is headquartered in Research Triangle Park, North Carolina.
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Valuation
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Growth (CAGR)
PROS
- Compounding revenue at 13.7% over 5 years.
- Generates positive free cash flow.
CONS
- Earnings shrank at -206.1% CAGR over 5 years.
- Trading 46.3% below its 52-week high.
- In a downtrend (50-DMA below 200-DMA).
* The pros and cons are auto-generated from financial metrics.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth
No fundamental data available for this stock.
Figures from the latest reported periods. CAGR is computed across the displayed window (quarterly CAGR is annualised assuming 4 quarters per year).
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | SLP Simulations Plus, Inc. R2K | 17.11 | - | $345.72M | - | 5.18% | -38.84% | 13.67% | -206.15% |
| 2 | LLY Eli Lilly and Company SPX | 1,105.00 | 39.21 | $985.37B | 0.63% | 38.44% | 107.46% | 31.69% | 48.96% |
| 3 | JNJ Johnson & Johnson SPX | 225.33 | 26.11 | $542.42B | 2.38% | 23.13% | 26.42% | 5.60% | 14.32% |
| 4 | UNH UnitedHealth Group Incorporated SPX | 380.31 | 28.66 | $345.38B | 2.32% | 9.60% | 12.18% | 11.35% | -15.69% |
| 5 | MRK Merck & Co., Inc. SPX | 118.72 | 33.44 | $293.22B | 2.86% | 20.66% | 18.94% | 3.12% | 7.93% |
| 6 | TMO Thermo Fisher Scientific Inc. SPX | 492.51 | 27.11 | $183.03B | 0.38% | 9.17% | 13.52% | -0.27% | -1.19% |
| 7 | AMGN Amgen Inc. NDXSPX | 336.79 | 23.42 | $181.77B | 2.99% | 18.02% | 101.32% | 11.77% | 5.58% |
| 8 | GILD Gilead Sciences, Inc. NDXSPX | 134.43 | 18.29 | $166.90B | 2.44% | 22.92% | 43.36% | 2.57% | 22.83% |
| 9 | ISRG Intuitive Surgical, Inc. NDXSPXAI | 424.64 | 51.53 | $150.39B | - | 15.96% | 17.23% | 17.39% | 29.26% |
Quarterly Results
Figures in USD.
| Metric | May 2015 | Nov 2015 | Feb 2016 | May 2016 | Aug 2016 | Nov 2016 | Feb 2017 | May 2017 | Aug 2017 | Nov 2017 | Feb 2018 | May 2018 | Aug 2018 | Nov 2018 | Feb 2019 | May 2019 | Aug 2019 | Nov 2019 | Feb 2020 | May 2020 | Aug 2020 | Nov 2020 | Feb 2021 | May 2021 | Aug 2021 | Nov 2021 | Feb 2022 | May 2022 | Nov 2022 | Feb 2023 | May 2023 | Nov 2023 | Feb 2024 | May 2024 | Nov 2024 | Feb 2025 | May 2025 | Aug 2025 | Nov 2025 | Feb 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 8.47M | 9.94M | - | - | 10.35M | 12.30M | - | - | - | - | - | - | - | - | - | - | 16.23M | 14.50M | 18.30M | 18.54M | - | 22.43M | 20.36M | 17.46M | 18.42M | 24.29M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 9.30M | 7.33M | 7.62M | 7.53M | 8.15M |
| Gross Profit | 4.81M | 3.75M | 3.90M | 4.82M | 2.90M | 4.08M | 4.15M | 5.30M | 4.29M | 5.33M | 5.24M | 6.53M | 4.57M | 5.34M | 6.26M | 7.61M | 5.74M | 6.76M | 7.68M | 9.63M | 6.87M | 8.27M | 10.24M | 10.31M | 7.06M | 9.66M | 11.97M | 12.40M | 9.29M | 13.13M | 13.27M | 9.85M | 13.22M | 13.26M | - | 13.13M | 13.03M | 9.84M | 10.89M | 16.14M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 10.41M | 10.04M | 9.19M | 10.18M | 10.51M |
| Operating Income | 2.85M | 1.73M | 1.72M | 2.79M | - | 1.93M | 1.79M | 3.10M | - | 2.56M | 2.42M | 3.42M | - | 2.09M | 2.73M | 3.88M | - | 2.72M | 2.83M | 3.86M | - | 3.05M | 3.49M | 4.54M | - | 3.79M | 5.48M | 4.95M | 878.00K | 4.03M | 4.10M | 960.00K | 4.44M | 1.88M | - | 2.71M | 3.00M | 659.00K | 713.00K | 5.63M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4.99M | 5.31M | 2.01M | 2.06M | 7.18M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 3.51M | -74.04M | 889.00K | 970.00K | 5.89M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 434.00K | -6.73M | 1.57M | 294.00K | 1.35M |
| Net Income | 1.85M | 1.11M | 1.15M | 1.91M | 789.00K | 1.36M | 1.20M | 2.08M | 1.15M | 1.72M | 3.48M | 2.41M | 1.34M | 1.54M | 2.10M | 2.89M | 2.06M | 2.06M | 2.15M | 2.94M | 2.19M | 2.48M | 3.21M | 3.79M | 305.00K | 3.03M | 4.41M | 4.09M | 1.25M | 4.17M | 4.01M | 1.95M | 4.03M | 3.14M | - | 3.07M | -67.32M | -681.00K | 676.00K | 4.54M |
| Diluted EPS | 0.11 | 0.06 | 0.07 | 0.11 | 0.06 | 0.08 | 0.07 | 0.12 | 0.06 | 0.10 | 0.19 | 0.13 | 0.07 | 0.09 | 0.12 | 0.16 | 0.11 | 0.11 | 0.12 | 0.16 | 0.11 | 0.12 | 0.15 | 0.18 | 0.01 | 0.15 | 0.21 | 0.20 | 0.06 | 0.20 | 0.20 | 0.10 | 0.20 | 0.15 | 0.01 | 0.15 | -3.35 | - | 0.03 | 0.22 |
| R&D Expense | 348.29K | 351.31K | 461.39K | 348.43K | - | 290.30K | 408.54K | 253.80K | - | 360.82K | 484.33K | 508.36K | - | 529.64K | 724.03K | 643.25K | - | 526.00K | 748.00K | 752.00K | - | 809.00K | 1.29M | 670.00K | - | 882.00K | 902.00K | 655.00K | 1.17M | 1.32M | 945.00K | 1.22M | 1.31M | 1.30M | 1.85M | 2.14M | 1.22M | - | 2.98M | 3.47M |
Profit & Loss (Annual)
Figures in USD.
| Metric | Aug 2012 | Aug 2013 | Aug 2014 | Aug 2015 | Aug 2016 | Aug 2017 | Aug 2018 | Aug 2019 | Aug 2020 | Aug 2021 | Aug 2022 | Aug 2023 | Aug 2024 | Aug 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | - | - | - | 53.91M | 59.58M | 70.01M | 79.18M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | 10.82M | 11.63M | 26.86M | 32.96M |
| Gross Profit | 7.94M | 8.42M | 9.83M | 13.92M | 15.37M | 17.83M | 21.67M | 24.94M | 30.94M | - | 43.08M | 47.95M | 43.15M | 46.22M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | 28.17M | 38.72M | 37.02M | 39.73M |
| Operating Income | 3.61M | 4.07M | 4.44M | 5.86M | 7.23M | 8.26M | 10.30M | 10.65M | 11.61M | - | 14.91M | 9.22M | 6.13M | 6.49M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | 18.48M | 13.06M | 11.80M | 14.70M |
| Interest Expense | - | - | - | - | - | - | - | - | - | 22.00K | 0 | 0 | - | - |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | 15.12M | 11.70M | 12.41M | -69.38M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | 2.63M | 1.73M | 2.46M | -4.66M |
| Net Income | 3.03M | 2.89M | 3.03M | 3.84M | 4.95M | 5.79M | 8.93M | 8.58M | 9.33M | - | 12.48M | 9.96M | 9.95M | -64.72M |
| Diluted EPS | 0.19 | 0.18 | 0.18 | 0.23 | 0.29 | 0.33 | 0.50 | 0.48 | 0.50 | - | 0.60 | 0.49 | 0.49 | -3.22 |
| R&D Expense | 947.56K | 802.37K | 952.77K | 1.33M | 1.45M | 1.37M | 1.79M | 2.50M | 2.98M | 4.05M | 3.21M | 4.50M | 5.75M | 6.88M |
Compounded Sales Growth
| 5 Years: | 13.67% |
| 1 Year: | 8.30% |
Compounded Profit Growth
| 5 Years: | -206.15% |
| 1 Year: | 46.70% |
Stock Price Performance
| 1 Year: | -46.28% |
| 6 Months: | -0.12% |
| 3 Months: | +39.90% |
| 1 Month: | +22.30% |
Balance Sheet (Annual)
Figures in USD.
| Metric | Aug 2011 | Aug 2012 | Aug 2013 | Aug 2014 | Aug 2015 | Aug 2016 | Aug 2017 | Aug 2018 | Aug 2019 | Aug 2020 | Aug 2021 | Aug 2022 | Aug 2023 | Aug 2024 | Aug 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | - | 17.35M | 16.06M | 20.98M | 27.34M | 27.81M | 38.51M | 43.28M | 45.20M | 168.42M | - | 188.38M | 186.10M | 196.64M | 131.94M |
| Current Assets | - | - | - | - | - | - | - | - | - | - | - | 146.79M | 130.37M | 39.34M | 51.55M |
| Cash & Equivalents | 10.18M | 12.70M | 10.18M | 8.61M | 8.55M | 8.03M | 6.22M | 9.40M | 11.43M | 49.21M | - | 51.57M | 57.52M | 10.31M | 30.85M |
| Inventory | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Receivables | - | - | - | - | - | - | - | - | - | - | - | 13.79M | 10.20M | 9.14M | 9.72M |
| Total Liabilities | - | 2.20M | 1.82M | 5.55M | 7.81M | 5.08M | 12.71M | 11.36M | 7.52M | 12.39M | - | 10.13M | 16.07M | 14.21M | 7.13M |
| Current Liabilities | - | 1.42M | 626.31K | 1.39M | 3.61M | 2.13M | 2.04M | 4.83M | 4.78M | 5.51M | - | 7.74M | 11.99M | 12.07M | 6.72M |
| Long Term Debt | - | - | - | - | - | - | 5.74M | 3.33M | - | - | - | - | - | - | - |
| Total Debt | - | - | - | - | - | - | - | - | - | - | - | 1.40M | 1.20M | 1.01M | 616.00K |
| Total Equity | 14.04M | 15.14M | 14.24M | 15.44M | 19.53M | 22.73M | 25.80M | 31.92M | 37.68M | 156.03M | - | 178.25M | 170.03M | 182.43M | 124.80M |
| Shares Outstanding | - | - | - | - | - | - | - | - | - | - | - | 20.26M | 19.94M | 20.05M | 20.14M |
Cash Flows (Annual)
Figures in USD.
| Metric | Aug 2012 | Aug 2013 | Aug 2014 | Aug 2015 | Aug 2016 | Aug 2017 | Aug 2018 | Aug 2019 | Aug 2020 | Aug 2021 | Aug 2022 | Aug 2023 | Aug 2024 | Aug 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | 3.78M | 2.56M | - | 7.14M | 5.42M | 6.88M | 9.29M | 11.64M | 10.91M | - | 17.90M | 21.86M | 13.32M | 18.13M |
| Investing Cash Flow | 839.49K | -1.18M | - | -3.13M | -1.95M | -4.36M | -2.33M | -1.96M | -75.50M | - | 4.30M | 7.37M | -53.97M | 3.56M |
| Financing Cash Flow | - | - | - | -4.07M | -3.98M | -4.34M | -3.77M | -7.65M | 102.37M | - | -7.62M | -23.27M | -6.57M | -1.15M |
| Capital Expenditure | -106.83K | -53.15K | -24.49K | -71.37K | -39.12K | -175.96K | -183.29K | -138.00K | -231.00K | - | -3.97M | -4.27M | -4.30M | -3.72M |
| Free Cash Flow | 3.68M | 2.51M | - | 7.06M | 5.38M | 6.70M | 9.10M | 11.50M | 10.68M | - | 13.93M | 17.58M | 9.02M | 14.40M |
| Net Change in Cash | - | - | - | - | - | - | - | - | - | - | 14.58M | 5.96M | -47.21M | 20.54M |
| Share Buybacks | - | - | - | - | - | - | - | - | - | 0 | 0 | 20.00M | 0 | 0 |
| Dividends Paid | 2.38M | 4.00M | 3.08M | 3.38M | 3.41M | 3.45M | 4.16M | 4.20M | 4.25M | 4.81M | 4.85M | 4.81M | 4.80M | 0 |
Ratios (Annual)
Figures in %.
| Metric | Aug 2012 | Aug 2013 | Aug 2014 | Aug 2015 | Aug 2016 | Aug 2017 | Aug 2018 | Aug 2019 | Aug 2020 | Aug 2021 | Aug 2022 | Aug 2023 | Aug 2024 | Aug 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | - | - | - | - | 79.9% | 80.5% | 61.6% | 58.4% |
| Operating Margin % | - | - | - | - | - | - | - | - | - | - | 27.7% | 15.5% | 8.8% | 8.2% |
| Net Margin % | - | - | - | - | - | - | - | - | - | - | 23.2% | 16.7% | 14.2% | -81.7% |
| ROE % | 20.0% | 20.3% | 19.6% | 19.7% | 21.8% | 22.4% | 28.0% | 22.8% | 6.0% | - | 7.0% | 5.9% | 5.5% | -51.9% |
| ROCE % | 22.7% | 26.4% | 22.7% | 24.7% | 28.2% | 22.7% | 26.8% | 26.3% | 7.1% | - | 8.3% | 5.3% | 3.3% | 5.2% |
Shareholding Pattern
Top Institutional Holders
| # | Holder | % Held | Shares | Value |
|---|---|---|---|---|
| 1 | First Light Asset Management, LLC | 13.03% | 2.63M | $45.05M |
| 2 | Blackrock Inc. | 6.20% | 1.25M | $21.43M |
| 3 | Morgan Stanley | 4.39% | 887.51K | $15.19M |
| 4 | First Eagle Investment Management, LLC | 3.67% | 742.07K | $12.70M |
| 5 | Vanguard Capital Management LLC | 3.66% | 739.72K | $12.66M |
| 6 | Marshall Wace LLP | 3.13% | 632.69K | $10.83M |
| 7 | Rockefeller Capital Management L.P. | 2.91% | 587.64K | $10.05M |
| 8 | Tributary Capital Management, LLC | 2.71% | 548.42K | $9.38M |
| 9 | Meros Investment Management, Lp | 2.47% | 500.02K | $8.56M |
| 10 | Royce & Associates LP | 2.12% | 427.42K | $7.31M |
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
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