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Skye Bioscience, Inc. SKYE PHARMA

Healthcare · Biotechnology · United States
https://skyebioscience.com
Company Profile ↓
$1.88
-40.13% 1Y
Mkt Cap$8.32M
P/E-0.18
P/B-15.62
52W High$38.00
52W Low$1.68
Book Value$-0.11
EPS (TTM)$-10.24

Company Overview

Skye Bioscience, Inc., a clinical-stage biotechnology company, develops molecules that modulate G-protein-coupled receptors to treat obesity, overweight, and related metabolic diseases. The company's lead clinical asset is nimacimab, a peripherally-restricted negative allosteric modulating antibody targeting cannabinoid receptor 1 (CB1) administered as a subcutaneous injectable, which targets CB1 receptors in peripheral tissues including adipose, liver, and muscle tissues with limited central nervous system accumulation. Nimacimab addresses metabolic processes related to energy expenditure, fat mobilization, leptin sensitivity, appetite regulation, and satiety signaling. Skye Bioscience, Inc. was formerly known as Emerald Bioscience Inc. and changed its name to Skye Bioscience, Inc. in December 2020. Skye Bioscience, Inc. was incorporated in 2011 and is based in San Diego, California.

Growth & Price Performance

Stock Price Performance

1 Year:-40.13%
6 Months:-67.54%
3 Months:-69.48%
1 Month:-54.72%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 1% of range
$1.68 $38.00
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)23.71 · Oversold
Price Performance
1M-54.72%
3M-69.48%
6M-67.54%
1Y-40.13%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 95.0% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).
  • RSI at 24 suggests oversold conditions.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-0.18
Industry PE
24.83
Forward P/E
-0.25
PEG Ratio
-
Book Value
$-0.11
Price to Book
-15.62
P/S
-
EV/EBITDA
0.04
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-
ROE
-
ROA
-95.06%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.32
EPS (TTM)
$-10.24

Balance Sheet & Liquidity

Debt/Equity
3.46
Quick Ratio
0.87
Current Ratio
0.95
Debt
$178.75K
Total Assets
$19.42M
Current Assets
$18.57M
Working Capital
$18.89M

Ownership

Promoter Holding
4.24%
Chg in Prom Hold
3.07%
FII / Inst Holding
44.49%
Chg in FII Hold
-1.35%

Financial Snapshot

Enterprise Value
$8.32M
Total Revenue (TTM)
$0
EBITDA
$-47.37M
Free Cash Flow
$-18.71M
Operating Cash Flow
$-38.81M
Shares Outstanding
4.43M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 SKYE Skye Bioscience, Inc. PHARMA 1.88 -0.18 $8.32M 0.00% - - - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Apr 2014Jun 2014Jul 2014Sep 2014Mar 2015Jun 2015Sep 2015Mar 2016Jun 2016Sep 2016Mar 2017Jun 2017Sep 2017Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue -----------------------------------00000
Cost of Revenue ----------------------------------------
Gross Profit ----------------------------------------
Operating Expenses -----------------------------------11.76M18.24M13.26M14.90M12.67M
Operating Income -13.43K-142.92K4.05K-857.61K-909.83K-1.36M-896.29K-1.22M-1.48M-856.15K-1.38M-730.93K-761.63K-1.25M-1.08M-1.05M-1.52M-1.77M-1.50M-2.21M-1.22M-1.54M-1.74M-1.83M-1.82M-2.89M-3.22M-2.92M-3.10M-2.84M-24.71M-6.15M-8.41M-4.97M--11.76M-18.24M-13.26M-14.90M-12.67M
EBITDA ------------------------------------10.92M-17.43M-12.58M-14.26M-12.33M
Interest Expense -----------------------------------1.45K0002.20K
Pretax Income ------------------------------------11.10M-17.62M-12.75M-14.44M-12.51M
Tax Provision -----------------------------------2.00K3.40K000
Net Income -13.51K-142.92K7.76K-858.52K-910.23K-2.06M-1.18M-1.69M573.09K-945.27K-1.28M-702.76K-480.13K-8.21M-2.66M-2.10M-14.77M15.91M-4.93M-2.34M-1.42M-1.30M-2.16M-2.02M-1.82M-3.04M-3.42M-3.13M-5.17M-3.11M-24.95M-5.02M-7.90M-3.90M--11.10M-17.62M-12.75M-14.44M-12.51M
Diluted EPS ------0.13--0.03-0.05-0.09-0.02-0.02-0.09-0.02-0.02-0.110.08-0.04-0.01-0.01-0.01-0.01-0.010.00-0.01-0.01-1.58-1.37-0.80-3.17-0.18-0.20-0.10--0.28-0.44-0.32-0.36-0.32
R&D Expense ---195.00K37.20K43.37K152.29K135.36K459.96K80.53K92.10K60.65K88.55K25.00K-67.29K320.99K688.04K513.00K799.61K428.53K346.22K609.66K880.67K327.73K1.27M1.43M1.78M1.18M1.79M----------

Profit & Loss (Annual)

Figures in USD.

Metric Oct 2012Oct 2013Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -----------0000
Cost of Revenue ---------------
Gross Profit ---------------
Operating Expenses -----------12.11M13.67M36.43M58.16M
Operating Income 4.12K-7.24K-120.40K-2.73M-4.32M-4.47M-3.86M-4.69M-6.63M-6.29M--12.11M-13.67M-36.43M-58.16M
EBITDA ------------18.70M-36.62M-25.29M-55.20M
Interest Expense -----------663.77K897.21K967.60K0
Pretax Income ------------19.47M-37.64M-26.56M-55.92M
Tax Provision -----------6.74K3.60K10.07K5.40K
Net Income 4.51K-3.78K-120.40K-2.73M-4.84M-3.18M-3.09M-19.19M1.05M-6.56M--19.48M-37.64M-26.57M-55.92M
Diluted EPS ------0.17-0.11-0.16-0.05-0.03--8.77-5.37-0.73-1.41
R&D Expense ---227.50K576.09K939.04K311.30K329.97K2.24M1.94M2.93M6.01M---

Balance Sheet (Annual)

Figures in USD.

Metric Oct 2011Oct 2012Dec 2012Oct 2013Dec 2013Sep 2014Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -42.88K-145.69K--348.35K3.51M323.36K557.22K1.96M2.00M2.67M-9.11M11.94M72.76M28.31M
Current Assets --------------8.94M11.65M70.83M27.09M
Cash & Equivalents 13.91K26.40K-52.19K-1.03M207.33K3.22M64.82K259.95K1.85M---1.24M1.26M68.42M5.88M
Inventory ------------------
Receivables --------------74.12K158.24K5.07K10.47K
Total Liabilities -4.33K-62.32K182.15K-801.89K3.04M1.77M1.36M17.52M1.45M2.22M-12.12M14.07M4.61M8.29M
Current Liabilities -4.33K-62.32K182.15K-801.09K581.86K661.96K805.97K15.94M970.82K787.20K-12.12M13.90M4.34M8.21M
Long Term Debt ------------------
Total Debt --------------1.98M4.62M455.59K273.65K
Total Equity 25.95K38.56K-61.75K83.38K-182.15K--453.55K-892.20K-2.91M-3.57M-15.56M548.06K450.79K--3.01M-2.13M68.15M20.02M
Shares Outstanding --------------3.65M12.35M30.97M33.38M

Cash Flows (Annual)

Figures in USD.

Metric Oct 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -----3.33M-3.94M-6.03M-6.05M--12.74M-13.95M-25.24M-43.06M
Investing Cash Flow -----19.65K-4.38K--7.23K-5.21M6.60M-245.62K-19.50M
Financing Cash Flow ----3.51M5.54M6.00M6.70M--208.79K16.44M83.56M29.57K
Capital Expenditure -49.12K-23.26K-1.98K-11.12K-19.65K-4.38K--7.23K--28.06K-12.55K-1.60M-6.31K
Free Cash Flow -----3.35M-3.95M--6.06M--12.77M-13.96M-26.84M-43.07M
Net Change in Cash ----------7.74M9.09M58.08M-62.53M

Ratios (Annual)

Figures in %.

Metric Oct 2012Oct 2013Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------------
Operating Margin % ---------------
Net Margin % ---------------
ROE % 11.7%-4.5%66.1%602.8%542.6%109.1%86.7%123.3%191.9%-1,455.4%-647.6%1,765.9%-39.0%-279.3%
ROCE % 10.7%-8.7%-603.4%-147.4%1,320.3%1,551.4%33.6%-646.5%-333.7%-402.5%697.3%-53.2%-289.3%

Shareholding Pattern

Insiders
4.24%
Institutions
44.49%
Public Float
46.47%

Top Institutional Holders

#Holder% HeldSharesValue
1 5AM Venture Management, LLC 27.33% 1.21M $2.14M
2 Versant Venture Management, LLC 5.67% 250.96K $442.95K
3 Baker Bros. Advisors, LP 4.45% 196.91K $347.54K
4 Vanguard Capital Management LLC 2.16% 95.48K $168.53K
5 Sphera Funds Management Ltd. 1.92% 84.87K $149.79K
6 Platinum Investment Management Ltd 0.66% 29.14K $51.43K
7 Blackrock Inc. 0.66% 29.11K $51.38K
8 Geode Capital Management, LLC 0.62% 27.26K $48.11K
9 Millennium Management Llc 0.56% 24.82K $43.80K
10 Vanguard Fiduciary Trust Co 0.29% 13.03K $23.00K

Analyst View

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Latest News

Recent headlines for SKYE

Google News Fri, 04 Sep 2026

Skye Bioscience Inc (SKYE) Stock Price, Quote, News & History - Benzinga

<a href="https://news.google.com/rss/articles/CBMiS0FVX3lxTE90YXY3YkZwcFpmR29BeG8tYTk2VEF0ZkYxVmQ0cTBMQWV4MFVHRDlCS1RuNHJDcGM3cENBVGJEaEN2UGNHZFdOUXgyUQ?oc=5" target="_blank">Skye Bioscience Inc (SKYE) Stock Price, Quote, News & History</a>…

Google News hu, 20 Aug 2026

Skye Bioscience (SKYE) insider funds sell 375,840 shares at $0.32–$0.41 - Stock Titan

<a href="https://news.google.com/rss/articles/CBMiswFBVV95cUxPQlZQTkRRcUhVSVkyX0d0WXZES05peTFzQjdVSm1Bcm12RElTYk4wUHVyUUQ0VmtrNXRkRTA0ZnJ5T1NHYkFEOG9rWFJVX2VUQUVwU0pUYm5RNWQwVGFFSDRrXzNWdlVINUZZbnBFTHUyTk5Vc2tnVkJlVmNQdE4yX0Vndl9wVmE4WFg1Yk…

Google News Fri, 14 Aug 2026

Skye Bioscience and Redx Pharma Announce Transaction Agreement and $125 Million in Financings - GlobeNewswire

<a href="https://news.google.com/rss/articles/CBMi9wFBVV95cUxNaGNWUVdJaGxlaFFaV1N3bWd1UUxzUFBpNThJbTNnQ3J0X3NRcXpnMEpTdWxmVXZ4TlJnZk93RXhGZTVGZ1RBWmUzeW1hQ3dIS21ETEcxdC0tY216alBVVVhpbjlQUjQzSF95a09LTGlNYjNlcnh2Umd0MVpPWThNWXVGZDIwRWVmQ1lJWn…

Google News hu, 20 Aug 2026

5am Partners VII, LLC sells $140,313 of Skye Bioscience stock - Investing.com

<a href="https://news.google.com/rss/articles/CBMiwAFBVV95cUxNYWE4UHpHZXdZT1MxUlB0YjE0ODVJWV9XekY5em0yOEt6S3N0R2x6WXFiS2plQ0NITjNPQUR1QmxDak12RXpPQmYwWWszSzQ5eVIzSnlLVnRBTUhwQVlVZjhKa1JaNllmNGxxcHI1X1RIMGkyQ3g3NUJoM0hzSWxtWUJEZGlPSWFEMXpla1…

Google News ue, 25 Aug 2026

Skye Bioscience (SKYE) Shares Rise 6% After Hours: Here's What's Driving The Move - webull.com

<a href="https://news.google.com/rss/articles/CBMiWEFVX3lxTFBVcmtRZG1zbVF0b2Q2RkFDVTdjTkR5ZVE2TExJam1pVE9TZllSbll3U3p5YWEtN1FEU1BiVkJIR0hPTlIzS1RFU3ZYUTkyZzlta1BfU3Nvc2s?oc=5" target="_blank">Skye Bioscience (SKYE) Shares Rise 6% After Hour…

Google News hu, 20 Aug 2026

Insider Sale: Director at $SKYE Sells 46 Shares | SKYE Stock News - Quiver Quantitative

<a href="https://news.google.com/rss/articles/CBMijAFBVV95cUxOcUx2OEZuVzhvYWdhQnZhOHdYZXRoN1Y3dldCRnNWUzN5SlBnXzcwY044Y2FMUjBZTXRTR3RGWkFJcjJRd1lCcFFZQ2VfRDRFMlVkYk1QZi12ZlozalRRZWNHbHowMnhoajV6Z1pKVUlBbWo0Ylh2MGloamtOU213RFBJdENXYzBySlBTeA…

SKYE — Frequently Asked Questions

What is the current share price of Skye Bioscience, Inc. (SKYE)?

As of 2026-09-19 21:16 PDT, Skye Bioscience, Inc. (SKYE) trades at $1.88 on NasdaqCM. Its 52-week range is $1.68 to $38.00.

What is the market capitalisation of SKYE?

Skye Bioscience, Inc. (SKYE) has a market capitalisation of $8.32M on NasdaqCM.

What is the P/E ratio of SKYE?

SKYE trades at a trailing price-to-earnings (P/E) ratio of -0.18. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is -15.62.

Is SKYE a good stock to buy?

This page provides a data-driven analysis of Skye Bioscience, Inc. (SKYE), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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