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Sera Prognostics, Inc. SERA PHARMA

Healthcare · Medical Devices · United States
https://www.sera.com
Company Profile ↓
$2.01
-12.61% 1Y
Mkt Cap$77.35M
P/E-3.05
P/B1.38
52W High$3.75
52W Low$1.59
Book Value$1.51
EPS (TTM)$-0.66

Company Overview

Sera Prognostics, Inc., a women's health company, discovers, develops, and commercializes blood-based biomarker tests, and predictive analytic products and services in the United States. The company develops the PreTRM test, a non-invasive blood test given to a pregnant woman, carrying a single fetus, during weeks 18 through 20 of gestation. It is also involved in the development of a pipeline of novel blood-based biomarker tests and predictive analytic products and services for pregnancy related conditions, such as time-to-birth, predictive analytics product, pregnancy risk prediction panel, preeclampsia, and fetal growth restriction. The company was incorporated in 2008 and is headquartered in Salt Lake City, Utah.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 34.2% CAGR over the past five years.

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.05.

Recent Developments

  • Dec 2025 Revenue of $81.00K (+5.2% YoY); net profit $-31.93M.
  • Trailing 12 Months Year-on-year growth — revenue +76.5%.
  • 5-Year Trend Long-term compounding — revenue CAGR 34.2%.

Growth & Price Performance

Compounded Sales Growth

5 Years:34.16%
1 Year:76.50%

Stock Price Performance

1 Year:-12.61%
6 Months:+4.15%
3 Months:-4.29%
1 Month:-2.90%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 19% of range
$1.59 $3.75
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)47.34 · Neutral
Price Performance
1M-2.90%
3M-4.29%
6M+4.15%
1Y-12.61%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 34.2% over 5 years.

CONS

  • Trading 46.4% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-3.05
Industry PE
24.83
Forward P/E
-3.76
PEG Ratio
-
Book Value
$1.51
Price to Book
1.38
P/S
1,175.03
EV/EBITDA
-1.06
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
34.16%
Profit 5Y
-
Revenue (YoY)
76.50%
Earnings (YoY)
-

Profitability & Returns

ROCE
-46.95%
ROE
-45.03%
ROA
-23.48%
Profit Margin
0.00%
Op Margin
-
Gross Margin
-
EPS (Latest Qtr)
$-0.17
EPS (TTM)
$-0.66

Balance Sheet & Liquidity

Debt/Equity
0.05
Quick Ratio
1.91
Current Ratio
1.98
Debt
$3.00M
Total Assets
$93.54M
Current Assets
$49.73M
Working Capital
$16.58M

Ownership

Promoter Holding
12.13%
Chg in Prom Hold
0.22%
FII / Inst Holding
50.21%
Chg in FII Hold
0.01%

Financial Snapshot

Enterprise Value
$77.35M
Total Revenue (TTM)
$70.00K
EBITDA
$-36.54M
Free Cash Flow
$-18.89M
Operating Cash Flow
$-27.68M
Shares Outstanding
38.48M
Gross Margin
-
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 SERA Sera Prognostics, Inc. PHARMA 2.01 -3.05 $77.35M 0.00% -46.95% -45.03% 34.16% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue -6.00K5.00K13.00K20.00K23.00K38.00K78.00K87.00K100.00K123.00K42.00K024.00K29.00K38.00K17.00K16.00K10.00K14.00K
Cost of Revenue ---------------40.00K41.00K41.00K42.00K42.00K
Gross Profit ----------------2.00K-24.00K-25.00K-32.00K-28.00K
Operating Expenses ---------------9.25M9.30M8.96M8.92M9.33M
Operating Income --4.28M-4.64M-6.03M-7.38M-9.44M-12.30M-11.75M-11.19M-11.33M-11.46M-8.18M-9.10M-9.25M-8.86M-9.25M-9.32M-8.98M-8.95M-9.36M
EBITDA ----------------7.97M-7.81M-7.57M-7.64M-8.20M
Interest Expense ---------------4.00K2.00K2.00K1.00K2.00K
Pretax Income ----------------8.19M-8.05M-7.81M-7.88M-8.40M
Tax Provision --------------------
Net Income -4.70M-4.71M-5.07M-6.36M-6.31M-9.86M-12.21M-11.52M-10.71M-10.56M-10.54M-7.21M-8.10M-8.30M-7.92M-8.19M-8.05M-7.81M-7.88M-8.40M
Diluted EPS ---3.30-3.55-3.17-0.39-0.40-0.37-0.35-0.34-0.34-0.23-0.25-0.25-0.24-0.20-0.16-0.16-0.16-0.17
R&D Expense -1.75M1.89M2.40M2.82M2.72M3.32M3.26M4.18M4.10M3.69M3.54M3.68M4.41M3.50M3.33M3.34M3.28M-3.03M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 25.00K-268.00K306.00K77.00K81.00K
Cost of Revenue --193.00K210.00K82.00K164.00K
Gross Profit --75.00K96.00K-5.00K-83.00K
Operating Expenses --45.73M39.92M36.63M36.42M
Operating Income -17.97M--45.65M-39.82M-36.63M-36.50M
EBITDA ---43.37M-35.29M-32.04M-30.98M
Interest Expense --61.00K55.00K28.00K9.00K
Pretax Income ---44.19M-36.24M-32.90M-31.93M
Tax Provision ------
Net Income -19.85M--44.19M-36.24M-32.90M-31.93M
Diluted EPS -12.76--1.43-1.16-0.99-0.67
R&D Expense 7.78M11.02M14.24M15.22M14.73M13.17M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -14.80M-116.33M95.44M72.58M101.93M
Current Assets ---90.12M61.34M47.60M40.77M
Cash & Equivalents -13.53M-29.88M3.88M4.04M3.94M
Inventory -------
Receivables ---113.00K160.00K34.00K12.00K
Total Liabilities -12.33M-17.39M25.28M24.77M26.52M
Current Liabilities -11.24M-15.54M24.44M24.77M24.19M
Long Term Debt -------
Total Debt ---2.83M1.86M840.00K2.34M
Total Equity -106.62M-125.57M-98.94M70.16M47.80M75.41M
Shares Outstanding ---31.02M31.70M34.17M38.94M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -16.87M--34.61M-27.19M-14.19M-25.62M
Investing Cash Flow -149.00K-5.55M438.00K11.74M-28.50M
Financing Cash Flow 9.16M-5.00K752.00K2.61M54.03M
Capital Expenditure -149.00K--791.00K-128.00K-1.10M-726.00K
Free Cash Flow -17.02M--35.40M-27.32M-15.29M-26.35M
Net Change in Cash ---29.05M-26.00M163.00K-99.00K

Ratios (Annual)

Figures in %.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % --28.0%31.4%-6.5%-102.5%
Operating Margin % -71,884.0%--17,034.3%-13,013.4%-47,577.9%-45,066.7%
Net Margin % -79,392.0%--16,487.3%-11,843.8%-42,724.7%-39,417.3%
ROE % 15.8%--44.7%-51.7%-68.8%-42.3%
ROCE % -505.7%--45.3%-56.1%-76.6%-47.0%

Shareholding Pattern

Insiders
12.13%
Institutions
50.21%
Public Float
57.14%

Top Institutional Holders

#Holder% HeldSharesValue
1 Baker Bros. Advisors, LP 14.29% 5.50M $11.46M
2 Whetstone Capital Advisors, LLC 8.59% 3.31M $6.89M
3 Aberdeen Group plc 7.16% 2.75M $5.74M
4 Vivo Capital, LLC 4.29% 1.65M $3.44M
5 Vanguard Capital Management LLC 3.37% 1.30M $2.71M
6 CAPTRUST Financial Advisors 1.39% 535.75K $1.12M
7 Geode Capital Management, LLC 0.91% 348.97K $727.60K
8 Blackrock Inc. 0.58% 221.37K $461.55K
9 AWM Investment Company, Inc. 0.54% 207.38K $432.39K
10 Vanguard Fiduciary Trust Co 0.44% 170.91K $356.34K

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for SERA

Yahoo Finance ue, 25 Aug 2026

1 in 10 U.S. Babies Are Born Too Early. A Leading OB-GYN Says Most Mothers Can Learn Their Risk by Week 21, and Do Something About It.

Preterm birth affects about 1 in 10 U.S. pregnancies. It's one of the most common pregnancy complications. It's also one nobody warns you about. Yet most expecting mothers never learn their own risk until something goes wrong, because docto…

Yahoo Finance Wed, 19 Aug 2026

Sera (SERA) Q2 2026 Earnings Call Transcript

Illinois Medicaid coverage for PreTRM test unlocks 50,000 annual births as payer access expands.

Yahoo Finance Wed, 19 Aug 2026

SERA PROGNOSTICS APPOINTS SCOTT GLEASON CHIEF FINANCIAL OFFICER

Sera Prognostics Inc., The Pregnancy Company® (Nasdaq: SERA), focused on improving maternal and neonatal health by providing innovative pregnancy biomarker information to doctors and patients, announced today that Scott Gleason has been app…

Yahoo Finance hu, 13 Aug 2026

Sera Prognostics Inc (SERA) (Q2 2026) Earnings Call Highlights: Payer Momentum Builds with ...

Despite minimal revenue, Sera Prognostics advances commercial strategy with new payer programs and a strengthened cash runway through 2029.

Yahoo Finance hu, 13 Aug 2026

Sera Prognostics Q2 Earnings Call Highlights

Sera Prognostics (NASDAQ:SERA) reported modest second-quarter revenue while outlining progress in payer engagement, Illinois Medicaid policy, clinical evidence and European regulatory preparations for its PreTRM Test-guided care platform. R…

Yahoo Finance Wed, 12 Aug 2026

Sera Prognostics, Inc. (SERA) Reports Q2 Loss, Misses Revenue Estimates

Sera Prognostics (SERA) delivered earnings and revenue surprises of -28.57% and -76.92%, respectively, for the quarter ended June 2026. Do the numbers hold clues to what lies ahead for the stock?

SERA — Frequently Asked Questions

What is the current share price of Sera Prognostics, Inc. (SERA)?

As of 2026-09-19 21:16 PDT, Sera Prognostics, Inc. (SERA) trades at $2.01 on NasdaqGM. Its 52-week range is $1.59 to $3.75.

What is the market capitalisation of SERA?

Sera Prognostics, Inc. (SERA) has a market capitalisation of $77.35M on NasdaqGM.

What is the P/E ratio of SERA?

SERA trades at a trailing price-to-earnings (P/E) ratio of -3.05. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 1.38.

What is the return on equity (ROE) of SERA?

SERA has a return on equity (ROE) of -45.03%. Its return on capital employed (ROCE) is -46.95%.

Is SERA a good stock to buy?

This page provides a data-driven analysis of Sera Prognostics, Inc. (SERA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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