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Rein Therapeutics Inc. RNTX PHARMA

Healthcare · Biotechnology · United States
https://www.reintx.com
Company Profile ↓
$0.86
-28.12% 1Y
Mkt Cap$74.19M
P/E-0.51
P/B6.72
52W High$1.88
52W Low$0.71
Book Value$0.12
EPS (TTM)$-1.68

Company Overview

Rein Therapeutics Inc., a biopharmaceutical company, focuses on developing medicines to address unmet medical needs in orphan pulmonary and fibrosis indications in the United States. The company's lead product candidate is LTI-03, a peptide, which is in Phase 2 clinical trial for the treatment of idiopathic pulmonary fibrosis (IPF). It also offers LTI-01, a proenzyme that has completed Phase 1b and Phase 2a clinical trials in LPE patients for the treatment of loculated pleural effusion. The company's pipeline also includes preclinical programs targeting cystic fibrosis and a peptide program focused on the caveolin-1 protein for systemic fibrosis indications; and LTI-05, an epithelial sodium channel, which is in preclinical trial phase for the treatment of cystic fibrosis. The company was formerly known as Aileron Therapeutics, Inc. and changed its name to Rein Therapeutics Inc. in February 2007. The company was incorporated in 2001 and is headquartered in Austin, Texas.

Growth & Price Performance

Stock Price Performance

1 Year:-28.12%
6 Months:-28.12%
3 Months:-9.11%
1 Month:+5.44%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Mixed
52-Week Range 13% of range
$0.71 $1.88
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMABelow
  • RSI (14)57.20 · Neutral
Price Performance
1M+5.44%
3M-9.11%
6M-28.12%
1Y-28.12%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 54.1% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-0.51
Industry PE
24.83
Forward P/E
-
PEG Ratio
-
Book Value
$0.12
Price to Book
6.72
P/S
-
EV/EBITDA
-3.54
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-121.99%
ROE
-96.42%
ROA
-21.02%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.19
EPS (TTM)
$-1.68

Balance Sheet & Liquidity

Debt/Equity
0.42
Quick Ratio
4.19
Current Ratio
4.27
Debt
$0
Total Assets
$26.29M
Current Assets
$5.45M
Working Capital
$-1.85M

Ownership

Promoter Holding
5.02%
Chg in Prom Hold
-0.35%
FII / Inst Holding
52.37%
Chg in FII Hold
0.14%

Financial Snapshot

Enterprise Value
$74.19M
Total Revenue (TTM)
$0
EBITDA
$-20.76M
Free Cash Flow
$-7.79M
Operating Cash Flow
$-18.83M
Shares Outstanding
86.27M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 RNTX Rein Therapeutics Inc. PHARMA 0.86 -0.51 $74.19M 0.00% -121.99% -96.42% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue -----00-000-000-000-000000000000-00000
Cost of Revenue --------------------------------------
Gross Profit --------------------------------------
Operating Expenses ---------------------------------5.61M6.87M5.49M3.96M5.23M
Operating Income -3.94M-5.55M-4.23M-4.45M-4.59M-4.95M-6.43M-7.04M-7.76M-9.66M-7.50M-6.98M-7.31M-7.38M-7.92M-7.35M-6.88M-4.40M-5.03M-4.19M-6.99M-6.01M-6.79M-8.42M-8.04M-6.48M-5.01M-1.99M-1.98M-7.21M-9.04M-6.07M--5.61M-6.87M-5.49M-3.96M-5.23M
EBITDA ----------------------------------5.61M-6.87M-5.49M-3.96M-5.23M
Interest Expense --------------------------------------
Pretax Income ----------------------------------5.50M-6.82M-5.58M-32.68M-5.84M
Tax Provision --------------------------------------
Net Income -3.92M-5.53M-4.22M-4.44M-4.56M-4.92M-6.26M-6.87M-7.59M-9.49M-7.43M-7.03M-7.21M-7.17M-7.75M-7.24M-6.75M-4.39M-5.02M-4.93M-6.97M-5.69M-6.70M-8.42M-7.99M-6.37M-4.78M-1.79M-1.83M-7.11M-8.94M-5.85M--5.50M-6.82M-5.58M-31.97M-5.84M
Diluted EPS ----------------------0.06-0.07-1.86-1.76-1.40-1.05-0.39-0.40-0.86-0.45-0.27--0.25-0.28-0.21--0.19
R&D Expense 2.49M2.09M2.60M3.09M2.94M3.16M3.83M4.31M4.85M5.32M4.32M3.96M4.17M4.30M4.47M4.71M4.07M2.49M2.68M1.93M4.32M3.85M4.28M5.89M5.43M4.24M1.81M187.00K22.00K3.46M3.74M3.72M-3.05M4.29M1.68M-3.07M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 000000-0000
Cost of Revenue -----------
Gross Profit -----------
Operating Expenses -------27.65M15.35M28.11M21.93M
Operating Income -12.89M-18.17M-23.01M-31.90M-29.96M-20.50M--27.65M-15.35M-28.11M-21.93M
EBITDA --------27.48M-15.23M-28.05M-21.93M
Interest Expense -----------
Pretax Income --------27.33M-15.68M-64.43M-50.58M
Tax Provision --------0-1.54M-712.00K
Net Income -12.88M-18.12M-22.60M-31.55M-29.37M-27.33M--27.33M-15.73M-62.88M-49.87M
Diluted EPS --------6.02-3.42-3.51-1.96
R&D Expense 7.83M10.28M14.24M18.45M17.66M11.17M17.01M17.97M3.99M14.25M11.03M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --22.02M52.69M30.31M26.47M16.34M-22.01M106.01M62.19M24.16M
Current Assets --------21.87M18.27M13.66M4.33M
Cash & Equivalents 6.21M3.77M20.71M11.86M10.63M5.31M7.05M-5.19M17.31M12.87M3.21M
Inventory ------------
Receivables ------------
Total Liabilities --4.08M4.89M10.71M10.43M4.18M-3.38M99.12M52.80M52.24M
Current Liabilities --4.07M4.89M5.37M5.84M3.96M-3.38M4.38M5.75M6.18M
Long Term Debt ------------
Total Debt -------162.00K33.00K48.00K0-
Total Equity -82.04M-94.32M-111.81M47.80M19.60M16.05M12.16M-18.62M6.89M9.39M-28.09M
Shares Outstanding --------4.54M4.89M21.67M27.55M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2015Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow --20.53M-27.93M-26.47M-20.48M--24.86M-19.81M-22.29M-19.36M
Investing Cash Flow --38.91M24.69M-2.81M6.41M-35.92M26.46M16.20M0-
Financing Cash Flow -50.59M2.52M23.96M15.80M-015.79M17.82M9.76M
Capital Expenditure -94.00K-142.00K-4.42M-151.00K-5.00K-157.00K----
Free Cash Flow --20.67M-32.35M-26.62M-20.48M--24.86M-19.81M-22.29M-19.36M
Net Change in Cash ------1.59M12.18M-4.47M-9.61M

Ratios (Annual)

Figures in %.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----------
Operating Margin % -----------
Net Margin % -----------
ROE % 13.7%16.2%-47.3%-161.0%-183.0%-224.7%--146.7%-228.4%-669.9%177.6%
ROCE % --101.2%-48.1%-127.9%-145.2%-165.5%--148.5%-15.1%-49.8%-122.0%

Shareholding Pattern

Insiders
5.02%
Institutions
52.37%
Public Float
55.14%

Top Institutional Holders

#Holder% HeldSharesValue
1 Voss Capital, LP 6.10% 5.26M $4.21M
2 Cable Car Capital, LP 6.02% 5.20M $4.16M
3 Adar1 Capital Management, LLC 5.22% 4.50M $3.60M
4 Vanguard Capital Management LLC 3.92% 3.38M $2.70M
5 Bios Capital Management, LP 3.46% 2.98M $2.39M
6 Ikarian Capital, LLC 3.42% 2.95M $2.36M
7 Great Point Partners LLC 2.98% 2.58M $2.06M
8 Citadel Advisors Llc 2.83% 2.44M $1.95M
9 Velan Capital Investment Management LP 1.97% 1.70M $1.36M
10 Senvest Management LLC 1.43% 1.23M $984.72K

Analyst View

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Latest News

Recent headlines for RNTX

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RNTX — Frequently Asked Questions

What is the current share price of Rein Therapeutics Inc. (RNTX)?

As of 2026-09-19 21:16 PDT, Rein Therapeutics Inc. (RNTX) trades at $0.86 on NasdaqCM. Its 52-week range is $0.71 to $1.88.

What is the market capitalisation of RNTX?

Rein Therapeutics Inc. (RNTX) has a market capitalisation of $74.19M on NasdaqCM.

What is the P/E ratio of RNTX?

RNTX trades at a trailing price-to-earnings (P/E) ratio of -0.51. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 6.72.

What is the return on equity (ROE) of RNTX?

RNTX has a return on equity (ROE) of -96.42%. Its return on capital employed (ROCE) is -121.99%.

Is RNTX a good stock to buy?

This page provides a data-driven analysis of Rein Therapeutics Inc. (RNTX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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