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REGENXBIO Inc. RGNX R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://www.regenxbio.com
Company Profile ↓
$8.94
+0.11% 1Y
Mkt Cap$590.16M
P/E-2.37
P/B8.09
52W High$15.98
52W Low$5.65
Book Value$1.32
EPS (TTM)$-3.78

Company Overview

REGENXBIO Inc., a clinical-stage biotechnology company, provides gene therapies that deliver functional genes to cells with genetic defects in the United States. Its gene therapy product candidates are based on NAV Technology Platform, a proprietary adeno-associated virus gene delivery platform. The company's products in pipeline includes ABBV-RGX-314 for the treatment of wet age-related macular degeneration, diabetic retinopathy, and other chronic retinal diseases; and RGX-202 for the treatment of Duchenne muscular dystrophy, as well as RGX-121 for the treatment of mucopolysaccharidosis type II. It also develops RGX-111 for the treatment of mucopolysaccharidosis type I. In addition, the company licenses its NAV Technology Platform to other biotechnology and pharmaceutical companies. Further, it has a collaboration and license agreement with AbbVie Global Enterprises Ltd. to develop ABBV-RGX-314 and with Nippon Shinyaku Co., Ltd. to develop RGX-121 and RGX-111 outside the United States. REGENXBIO Inc. was incorporated in 2008 and is headquartered in Rockville, Maryland.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 32.0% CAGR over the past five years.

Healthy Margins

Operating margin of 27.1% supports profitability.

Recent Developments

  • Dec 2025 Revenue of $170.44M (+104.5% YoY); net profit $-193.88M.
  • Trailing 12 Months Year-on-year growth — revenue +405.7%.
  • 5-Year Trend Long-term compounding — revenue CAGR 32.0%.

Growth & Price Performance

Compounded Sales Growth

5 Years:32.01%
1 Year:405.70%

Stock Price Performance

1 Year:+0.11%
6 Months:+3.35%
3 Months:+47.04%
1 Month:-20.74%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 32% of range
$5.65 $15.98
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)41.43 · Neutral
Price Performance
1M-20.74%
3M+47.04%
6M+3.35%
1Y+0.11%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 32.0% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

  • Trading 44.1% below its 52-week high.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-2.37
Industry PE
25.17
Forward P/E
-3.33
PEG Ratio
-
Book Value
$1.32
Price to Book
8.09
P/S
4.06
EV/EBITDA
-5.73
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
32.01%
Profit 5Y
-
Revenue (YoY)
405.70%
Earnings (YoY)
-

Profitability & Returns

ROCE
-48.13%
ROE
-137.63%
ROA
-21.20%
Profit Margin
-
Op Margin
27.09%
Gross Margin
-44.47%
EPS (Latest Qtr)
$0.43
EPS (TTM)
$-3.78

Balance Sheet & Liquidity

Debt/Equity
3.49
Quick Ratio
2.57
Current Ratio
2.86
Debt
$250.46M
Total Assets
$386.62M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
6.27%
Chg in Prom Hold
-0.27%
FII / Inst Holding
65.53%
Chg in FII Hold
0.01%

Financial Snapshot

Enterprise Value
$590.16M
Total Revenue (TTM)
$174.48M
EBITDA
$-148.78M
Free Cash Flow
$-184.74M
Operating Cash Flow
$-246.67M
Shares Outstanding
66.01M
Gross Margin
-44.47%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 RGNX REGENXBIO Inc. R2KR3KPHARMA 8.94 -2.37 $590.16M 0.00% -48.13% -137.63% 32.01% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue -------455.00K6.56M1.34M2.04M132.39M40.03M5.31M40.78M884.00K7.88M14.70M11.77M17.64M16.57M98.91M21.45M18.88M22.04M30.77M22.22M32.65M26.51M19.14M19.98M28.91M15.62M22.30M24.20M89.01M21.36M29.73M6.39M108.02M
Operating Income -6.30M-7.35M--11.25M-14.95M-18.67M--22.92M-15.06M-21.31M-102.03M6.35M-22.73M--35.91M-36.87M-35.90M--37.70M-41.83M13.95M--44.04M-52.23M-57.35M-71.53M-62.53M-71.05M-66.16M-73.11M-64.96M-63.86M-56.04M-62.08M12.13M-63.28M-52.41M-83.36M29.26M
Net Income -6.29M-7.33M-5.18M-10.77M-14.44M-18.15M-19.61M-21.99M-14.47M-20.71M-16.00M104.24M10.59M-19.20M4.31M-32.23M-1.46M-34.58M-26.46M-40.04M-33.76M8.79M-46.24M-50.14M-57.64M-58.41M-76.72M-68.18M-75.48M-66.68M-72.06M-61.87M-63.33M-52.99M-59.60M6.08M-70.87M-61.94M-90.05M22.71M
Diluted EPS --------0.82-0.47-0.67-0.513.040.30-0.560.11-0.89-0.04-0.94-0.72-1.08-0.910.23-1.24--1.36-1.37-1.79-1.58-1.75-1.53-1.66-1.41-1.38-1.05-1.170.12-1.38-1.20-1.720.43
R&D Expense 4.01M5.66M4.81M6.18M10.68M12.56M16.06M16.62M13.92M12.52M14.17M19.55M21.49M18.51M24.33M25.20M29.48M35.69M33.81M37.03M38.11M43.97M47.18M39.72M45.88M47.85M55.63M61.01M63.31M58.52M59.89M58.18M54.84M48.87M54.43M53.09M59.50M56.10M57.34M56.09M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 6.09M6.12M7.59M4.59M10.39M218.50M35.23M154.57M470.35M112.72M90.24M83.33M170.44M
Operating Income -4.78M-3.68M-23.14M-65.34M-75.89M88.10M-149.00M-119.23M159.98M-262.88M-268.13M-233.35M-161.20M
Net Income -5.39M-4.00M-22.81M-62.97M-73.17M99.94M-94.73M-111.25M127.84M-280.32M-263.49M-227.10M-193.88M
Diluted EPS ----2.38-2.452.73-2.58-2.982.91-6.50-6.02-4.59-3.76
R&D Expense 5.05M4.96M17.28M45.48M57.22M83.87M124.19M166.29M181.44M242.45M232.27M208.52M228.30M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --3.49M221.38M172.73M198.68M543.81M497.91M708.16M1.11B833.27M573.97M465.99M453.03M
Total Equity -8.11M-13.92M-18.29M216.81M161.74M183.03M508.85M450.20M377.75M764.30M516.20M311.74M259.65M102.73M
Cash & Equivalents 2.17M1.12M1.12M54.12M24.84M46.66M75.56M69.51M338.43M345.21M96.95M34.52M57.53M34.47M
Total Liabilities --9.19M4.57M10.99M15.65M34.97M47.71M330.41M349.61M317.07M262.23M206.34M350.30M
Current Liabilities --9.19M4.34M9.67M14.44M22.18M33.68M81.45M130.47M130.43M130.27M103.19M118.09M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow --48.56M-57.99M104.65M-107.70M-54.06M218.88M-207.49M-218.41M-173.12M-123.96M
Investing Cash Flow -19.39M-4.79M-279.36M93.56M122.76M-406.64M-11.93M190.94M103.45M-15.87M
Financing Cash Flow -119.00K84.60M204.44M8.38M200.21M195.25M-28.84M-34.97M92.68M116.77M
Capital Expenditure -522.00K-8.15M-7.16M-13.28M-11.72M-26.87M-84.17M-30.72M-9.96M-2.44M-2.41M
Free Cash Flow --56.71M-65.15M91.37M-119.42M-80.93M134.70M-238.21M-228.37M-175.56M-126.38M

Ratios (Annual)

Figures in %.

Metric Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -------------
Operating Margin % -78.5%-60.2%-304.9%-1,423.8%-730.2%40.3%-422.9%-77.1%34.0%-233.2%-297.1%-280.0%-94.6%
Net Margin % -88.5%-65.4%-300.6%-1,372.1%-704.0%45.7%-268.9%-72.0%27.2%-248.7%-292.0%-272.5%-113.8%
ROE % 38.7%21.9%-10.5%-38.9%-40.0%19.6%-21.0%-29.5%16.7%-54.3%-84.5%-87.5%-188.7%
ROCE % -64.6%-10.7%-40.1%-41.2%16.9%-32.1%-19.0%16.3%-37.4%-60.4%-64.3%-48.1%

Shareholding Pattern

Insiders
6.27%
Institutions
65.53%
Public Float
69.92%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 9.69% 6.40M $61.80M
2 Redmile Group, LLC 6.62% 4.37M $42.20M
3 State Street Corporation 4.50% 2.97M $28.70M
4 JPMORGAN CHASE & CO 3.35% 2.21M $21.39M
5 Vanguard Capital Management LLC 3.19% 2.11M $20.36M
6 Morgan Stanley 2.96% 1.95M $18.87M
7 Goldman Sachs Group Inc 2.15% 1.42M $13.73M
8 AQR Capital Management, LLC 2.09% 1.38M $13.31M
9 Vanguard Portfolio Management LLC 2.05% 1.36M $13.09M
10 Marshall Wace LLP 1.95% 1.28M $12.41M

Analyst View

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Latest News

Recent headlines for RGNX

Yahoo Finance Sat, 05 Sep 2026

Regenxbio’s Gene Therapy Faces Another FDA Setback in Hunter Syndrome

Regenxbio Inc. (NASDAQ:RGNX) suffered another setback in its effort to bring RGX-121 to patients with Hunter syndrome. The FDA placed the experimental gene therapy on clinical hold after spinal scans identified abnormalities in five treated…

Yahoo Finance ue, 25 Aug 2026

REGENXBIO Strengthens Board of Directors with Appointment of Greg Ciongoli

REGENXBIO Inc. (Nasdaq: RGNX) today announced the appointment of Greg Ciongoli to its Board of Directors, effective August 25, 2026. With multiple upcoming catalysts across its late-stage pipeline of potential first-and best-in-class gene t…

Yahoo Finance ue, 25 Aug 2026

Regenxbio’s RGX-121 Setback Carries A Potential Cash Risk, Warns Clear Street

Clear Street said the FDA decision would significantly delay Regenxbio’s resubmission of its application and a potential voucher that could bring in additional cash.

Yahoo Finance Mon, 24 Aug 2026

RGNX Stock On Track For Worst Day In Over Three Months — BofA Says Buy Despite ‘Disappointing’ FDA Hold On Gene Therapy

BofA called the clinical hold on RGX-121 disappointing and a reversal of July’s progress but kept a $15 price target on the stock.

Yahoo Finance Mon, 24 Aug 2026

Why Regenxbio Halted Its Gene Therapy Trial—and Why the Stock Is Tumbling

Regenxbio reports the discovery of nodules and masses on the spines of patients enrolled in a trial for RGX-121, the company’s investigational therapy for Hunter syndome.

Yahoo Finance Mon, 24 Aug 2026

Why Did RGNX Stock Crash Today?

Regenxbio said the FDA has placed a clinical hold on its Hunter syndrome therapy after the discovery of unusual spine MRI findings in five participants in a study.

RGNX — Frequently Asked Questions

What is the current share price of REGENXBIO Inc. (RGNX)?

As of 2026-09-07 16:24 PDT, REGENXBIO Inc. (RGNX) trades at $8.94 on NasdaqGS. Its 52-week range is $5.65 to $15.98.

What is the market capitalisation of RGNX?

REGENXBIO Inc. (RGNX) has a market capitalisation of $590.16M on NasdaqGS.

What is the P/E ratio of RGNX?

RGNX trades at a trailing price-to-earnings (P/E) ratio of -2.37. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 8.09.

What is the return on equity (ROE) of RGNX?

RGNX has a return on equity (ROE) of -137.63%. Its return on capital employed (ROCE) is -48.13%.

Is RGNX a good stock to buy?

This page provides a data-driven analysis of REGENXBIO Inc. (RGNX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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