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Precigen, Inc. PGEN R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://precigen.com
Company Profile ↓
$7.10
+271.73% 1Y
Mkt Cap$2.53B
P/E-6.64
P/B126.84
52W High$7.44
52W Low$1.85
Book Value$0.06
EPS (TTM)$-1.07

Company Overview

Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting of AdenoVerse platform, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients. It also develops programs based on the UltraCAR-T platform, including PRGN-3005 in Phase 1/1b clinical trial to treat advanced ovarian, fallopian tube, or primary peritoneal cancer; PRGN-3006 in Phase 1b trial for patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndromes; and PRGN-3007 in Phase 1/1b trial for the treatment of advanced receptor tyrosine kinase-like orphan receptor 1-positive, hematologic, and solid tumors. In addition, the company is developing programs based on the AdenoVerse immunotherapy platform comprising PRGN-2009 in Phase 2 trial for patients with HPV+ solid tumors; and PRGN-2012 in Phase ½ trial to treat recurrent respiratory papillomatosis. Further, it provides UltraPorator, a proprietary electroporation device. The company was formerly known as Intrexon Corporation and changed its name to Precigen, Inc. in February 2020. Precigen, Inc. was founded in 1998 and is headquartered in Germantown, Maryland.

Why Investors Should Care

Healthy Margins

Operating margin of 41.2% supports profitability.

Recent Developments

  • Dec 2025 Revenue of $9.68M (+146.7% YoY); net profit $-250.64M.
  • 5-Year Trend Long-term compounding — revenue CAGR 1.4%.

Growth & Price Performance

Compounded Sales Growth

5 Years:1.36%
1 Year:-

Stock Price Performance

1 Year:+271.73%
6 Months:+113.86%
3 Months:+98.32%
1 Month:+2.75%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 94% of range
$1.85 $7.44
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)57.84 · Neutral
Price Performance
1M+2.75%
3M+98.32%
6M+113.86%
1Y+271.73%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-6.64
Industry PE
25.17
Forward P/E
-32.27
PEG Ratio
-
Book Value
$0.06
Price to Book
126.84
P/S
30.07
EV/EBITDA
-74.91
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
1.36%
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-93.49%
ROE
-
ROA
-18.14%
Profit Margin
-
Op Margin
41.18%
Gross Margin
53.01%
EPS (Latest Qtr)
$0.05
EPS (TTM)
$-1.07

Balance Sheet & Liquidity

Debt/Equity
2.26
Quick Ratio
3.76
Current Ratio
4.58
Debt
$98.34M
Total Assets
$170.30M
Current Assets
$101.67M
Working Capital
$80.57M

Ownership

Promoter Holding
12.67%
Chg in Prom Hold
0.01%
FII / Inst Holding
72.49%
Chg in FII Hold
0.04%

Financial Snapshot

Enterprise Value
$2.53B
Total Revenue (TTM)
$85.72M
EBITDA
$-35.36M
Free Cash Flow
$-100.10M
Operating Cash Flow
$-114.17M
Shares Outstanding
356.51M
Gross Margin
53.01%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 PGEN Precigen, Inc. R2KR3KPHARMA 7.10 -6.64 $2.53B 0.00% -93.49% - 1.36% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue ---------46.02M-39.67M45.27M32.45M-22.59M32.84M18.30M17.00M29.84M30.42M23.58M19.33M24.51M3.81M3.33M5.51M2.91M16.72M1.85M1.77M----1.34M--23.25M54.98M
Operating Income -17.43M-7.92M-34.40M-40.53M-23.22M-28.82M-32.59M-31.38M-35.27M-44.75M-26.49M-42.24M-34.81M-58.33M-268.12M-41.85M-21.51M-34.70M-68.72M-16.60M-11.83M-23.01M-35.17M-------------22.60M---5.99M22.64M
Net Income -40.66M-38.21M-32.71M-64.43M-49.06M-28.98M-44.14M-31.40M-18.66M-39.69M-27.27M-46.16M-65.38M-57.32M-340.46M-60.71M-38.77M-53.63M-169.22M-56.00M-43.35M-29.51M-41.66M-17.32M-20.05M-29.76M-19.25M-17.64M87.38M-22.73M-20.32M-19.80M-23.74M-58.79M-23.98M-54.15M-26.64M-146.34M-7.93M20.07M
Diluted EPS -0.37-0.34-0.28-0.55----------------0.35-0.26-0.18--0.09-0.10-0.15-0.10-0.090.44-0.10-0.08-0.08-0.10-0.23-0.09-0.18-0.09-1.06-0.020.05
R&D Expense 20.38M21.60M-25.86M28.38M29.04M-34.18M34.01M36.47M-37.27M42.05M44.88M-33.06M34.52M31.48M-----------------10.48M--5.64M7.28M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 8.01M13.77M23.76M71.93M173.60M190.93M219.46M151.18M90.72M31.99M14.27M26.91M6.22M3.92M9.68M
Operating Income -82.43M-75.16M-58.02M-69.96M-146.86M-125.17M-137.89M-505.61M-----99.76M-135.03M-110.51M
Net Income -85.28M-81.87M-38.98M-81.82M-84.49M-186.61M-117.02M-509.34M-322.32M-170.52M-92.17M28.32M-95.90M-126.23M-250.64M
Diluted EPS ---------2.09-1.02-0.470.14-0.39-0.47-1.37
R&D Expense 70.23M64.03M48.14M58.98M147.48M112.14M143.21M404.59M----48.61M53.07M41.33M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --151.65M469.47M576.27M982.05M949.07M846.85M716.18M455.76M314.59M359.86M215.98M151.04M145.27M155.50M
Total Equity -127.73M-221.26M-321.55M366.72M384.76M694.08M560.24M533.63M362.86M71.71M67.17M107.35M126.26M118.50M38.51M20.91M
Cash & Equivalents 17.37M19.63M10.40M49.51M27.47M135.78M62.61M68.11M96.88M65.79M51.79M36.42M4.86M7.58M29.52M30.23M
Long Term Debt ---1.65M8.69M7.60M7.56M7.54M211.22M186.32M171.52M179.88M0-093.17M
Total Liabilities --66.54M88.13M166.98M277.16M379.82M300.31M337.45M384.05M247.41M252.51M89.72M32.55M78.53M134.59M
Current Liabilities --16.72M19.83M47.48M75.90M94.61M80.17M61.56M122.91M42.13M34.65M78.64M22.98M21.52M37.31M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -81.76M-61.53M-53.68M-19.86M35.67M-48.99M-103.72M-124.24M-135.93M-77.02M-55.77M-65.05M-66.93M-68.17M-87.83M
Investing Cash Flow -64.10M-23.64M-223.66M-26.03M-259.25M-28.39M104.33M-151.21M86.85M27.78M-74.54M226.42M-3.09M-20.71M-1.53M
Financing Cash Flow 148.11M75.94M316.45M24.00M331.68M12.06M4.28M309.80M8.14M32.70M121.19M-155.29M29.59M110.58M90.05M
Capital Expenditure -13.00M-7.49M-1.53M-6.37M-12.75M-31.63M-46.67M-41.59M-37.88M-7.53M-7.25M-4.92M-1.54M-8.58M-2.00M
Free Cash Flow -94.76M-69.02M-55.21M-26.23M22.92M-80.62M-150.39M-165.83M-173.81M-84.55M-63.02M-69.97M-68.47M-76.76M-89.83M

Ratios (Annual)

Figures in %.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------------
Operating Margin % -1,028.7%-545.6%-244.2%-97.3%-84.6%-65.6%-62.8%-334.4%-----1,602.5%-3,440.2%-1,141.1%
Net Margin % -1,064.3%-594.4%-164.1%-113.8%-48.7%-97.7%-53.3%-336.9%-355.3%-533.0%-646.0%105.2%-1,540.6%-3,216.2%-2,588.2%
ROE % 38.5%25.5%-10.6%-21.3%-12.2%-33.3%-21.9%-140.4%-449.5%-253.8%-85.9%22.4%-80.9%-327.8%-1,198.6%
ROCE % --55.7%-12.9%-13.2%-16.2%-14.6%-18.0%-77.2%-----77.9%-109.1%-93.5%

Shareholding Pattern

Insiders
12.67%
Institutions
72.49%
Public Float
83.01%

Top Institutional Holders

#Holder% HeldSharesValue
1 Patient Capital Management, LLC 5.34% 19.04M $132.31M
2 Blackrock Inc. 4.81% 17.15M $119.17M
3 State Street Corporation 3.37% 12.00M $83.42M
4 Diametric Capital, Lp 2.60% 9.27M $64.43M
5 Vanguard Capital Management LLC 2.22% 7.91M $54.95M
6 Tang Capital Management, LLC 1.80% 6.42M $44.60M
7 Boxer Capital Management, LLC 1.44% 5.15M $35.79M
8 Geode Capital Management, LLC 1.41% 5.02M $34.88M
9 Iridian Asset Management LLC 1.13% 4.03M $28.02M
10 Occam Crest Management LP 1.01% 3.61M $25.06M

Analyst View

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PGEN — Frequently Asked Questions

What is the current share price of Precigen, Inc. (PGEN)?

As of 2026-09-07 16:24 PDT, Precigen, Inc. (PGEN) trades at $7.10 on NasdaqGS. Its 52-week range is $1.85 to $7.44.

What is the market capitalisation of PGEN?

Precigen, Inc. (PGEN) has a market capitalisation of $2.53B on NasdaqGS.

What is the P/E ratio of PGEN?

PGEN trades at a trailing price-to-earnings (P/E) ratio of -6.64. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 126.84.

Is PGEN a good stock to buy?

This page provides a data-driven analysis of Precigen, Inc. (PGEN), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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