Precigen, Inc. PGEN R2K
Precigen, Inc.,a discovery and clinical-stage biopharmaceutical company, develops gene and cell therapies using precision technology to target diseases in areas of immuno-oncology, autoimmune disorders, and infectious diseases. The company offers therapeutic platforms consisting of AdenoVerse platform, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients. It also develops programs based on the UltraCAR-T platform, including PRGN-3005 in Phase 1/1b clinical trial to treat advanced ovarian, fallopian tube, or primary peritoneal cancer; PRGN-3006 in Phase 1b trial for patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndromes; and PRGN-3007 in Phase 1/1b trial for the treatment of advanced receptor tyrosine kinase-like orphan receptor 1-positive, hematologic, and solid tumors. In addition, the company is developing programs based on the AdenoVerse immunotherapy platform comprising PRGN-2009 in Phase 2 trial for patients with HPV+ solid tumors; and PRGN-2012 in Phase ½ trial to treat recurrent respiratory papillomatosis. Further, it provides UltraPorator, a proprietary electroporation device. The company was formerly known as Intrexon Corporation and changed its name to Precigen, Inc. in February 2020. Precigen, Inc. was founded in 1998 and is headquartered in Germantown, Maryland.
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Valuation
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Growth (CAGR)
PROS
- In a confirmed uptrend (50-DMA above 200-DMA).
CONS
- Revenue declined at -28.9% CAGR over 5 years.
- Earnings shrank at -328.4% CAGR over 5 years.
* The pros and cons are auto-generated from financial metrics.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth
No fundamental data available for this stock.
Figures from the latest reported periods. CAGR is computed across the displayed window (quarterly CAGR is annualised assuming 4 quarters per year).
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | PGEN Precigen, Inc. R2K | 4.34 | - | $1.55B | - | - | - | -28.87% | -328.38% |
| 2 | LLY Eli Lilly and Company SPX | 1,105.00 | 39.21 | $985.37B | 0.63% | 38.44% | 107.46% | 31.69% | 48.96% |
| 3 | JNJ Johnson & Johnson SPX | 225.33 | 26.11 | $542.42B | 2.38% | 23.13% | 26.42% | 5.60% | 14.32% |
| 4 | UNH UnitedHealth Group Incorporated SPX | 380.31 | 28.66 | $345.38B | 2.32% | 9.60% | 12.18% | 11.35% | -15.69% |
| 5 | MRK Merck & Co., Inc. SPX | 118.72 | 33.44 | $293.22B | 2.86% | 20.66% | 18.94% | 3.12% | 7.93% |
| 6 | TMO Thermo Fisher Scientific Inc. SPX | 492.51 | 27.11 | $183.03B | 0.38% | 9.17% | 13.52% | -0.27% | -1.19% |
| 7 | AMGN Amgen Inc. NDXSPX | 336.79 | 23.42 | $181.77B | 2.99% | 18.02% | 101.32% | 11.77% | 5.58% |
| 8 | GILD Gilead Sciences, Inc. NDXSPX | 134.43 | 18.29 | $166.90B | 2.44% | 22.92% | 43.36% | 2.57% | 22.83% |
| 9 | ISRG Intuitive Surgical, Inc. NDXSPXAI | 424.64 | 51.53 | $150.39B | - | 15.96% | 17.23% | 17.39% | 29.26% |
Quarterly Results
Figures in USD.
| Metric | Sep 2015 | Dec 2015 | Mar 2016 | Jun 2016 | Sep 2016 | Dec 2016 | Mar 2017 | Jun 2017 | Sep 2017 | Dec 2017 | Mar 2018 | Jun 2018 | Sep 2018 | Dec 2018 | Mar 2019 | Jun 2019 | Sep 2019 | Dec 2019 | Mar 2020 | Jun 2020 | Sep 2020 | Dec 2020 | Mar 2021 | Jun 2021 | Sep 2021 | Mar 2022 | Jun 2022 | Sep 2022 | Mar 2023 | Jun 2023 | Sep 2023 | Mar 2024 | Jun 2024 | Sep 2024 | Dec 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | - | 46.02M | - | 39.67M | 45.27M | 32.45M | - | 22.59M | 32.84M | 18.30M | 17.00M | 29.84M | 30.42M | 23.58M | 19.33M | 24.51M | 3.81M | 3.33M | 5.51M | 2.91M | 16.72M | 1.85M | 1.77M | - | - | - | - | - | 1.34M | 856.00K | 2.92M | 4.57M | 23.25M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1.10M | 1.09M | 1.03M | 1.60M | 2.56M |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 241.00K | -236.00K | 1.89M | 2.97M | 20.69M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 22.84M | 27.62M | 36.37M | 24.64M | 26.69M |
| Operating Income | -7.92M | -34.40M | -40.53M | -23.22M | -28.82M | -32.59M | -31.38M | -35.27M | -44.75M | -26.49M | -42.24M | -34.81M | -58.33M | -268.12M | -41.85M | -21.51M | -34.70M | -68.72M | -16.60M | -11.83M | -23.01M | -35.17M | - | - | - | - | - | - | - | - | - | - | - | - | - | -22.60M | -27.86M | -34.48M | -21.67M | -5.99M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -53.52M | -26.01M | -144.64M | -19.40M | -3.92M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1.00K | 0 | 902.00K | 2.96M | 2.91M |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -54.15M | -26.64M | -146.34M | -23.50M | -7.93M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 3.00K | 0 | 0 | 0 |
| Net Income | -38.21M | -32.71M | -64.43M | -49.06M | -28.98M | -44.14M | -31.40M | -18.66M | -39.69M | -27.27M | -46.16M | -65.38M | -57.32M | -340.46M | -60.71M | -38.77M | -53.63M | -169.22M | -56.00M | -43.35M | -29.51M | -41.66M | -17.32M | -20.05M | -29.76M | -19.25M | -17.64M | 87.38M | -22.73M | -20.32M | -19.80M | -23.74M | -58.79M | - | - | -54.15M | -26.64M | -146.34M | -23.50M | -7.93M |
| Diluted EPS | -0.34 | -0.28 | -0.55 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -0.35 | -0.26 | -0.18 | - | -0.09 | -0.10 | -0.15 | -0.10 | -0.09 | 0.44 | -0.10 | -0.08 | -0.08 | -0.10 | -0.23 | -0.09 | - | -0.18 | -0.09 | -1.06 | - | -0.02 |
| R&D Expense | 21.60M | - | 25.86M | 28.38M | 29.04M | - | 34.18M | 34.01M | 36.47M | - | 37.27M | 42.05M | 44.88M | - | 33.06M | 34.52M | 31.48M | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 10.48M | - | - | - | 5.64M |
Profit & Loss (Annual)
Figures in USD.
| Metric | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | 190.93M | 219.46M | 151.18M | 90.72M | 31.99M | - | 26.91M | 6.22M | 3.92M | 9.68M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | 6.34M | 6.12M | 4.27M | 4.82M |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | 20.57M | 106.00K | -342.00K | 4.86M |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | 95.18M | 89.03M | 94.36M | 111.46M |
| Operating Income | -82.43M | -75.16M | -58.02M | -69.96M | -146.86M | -125.17M | -137.89M | -505.61M | - | - | - | -74.61M | -88.92M | -94.70M | -106.60M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | -62.43M | -89.23M | -123.50M | -243.57M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | 6.77M | 468.00K | 6.00K | 3.87M |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | -79.97M | -96.36M | -128.03M | -250.64M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | -189.00K | -458.00K | -1.79M | 3.00K |
| Net Income | -85.28M | -81.87M | -38.98M | -81.82M | -84.49M | -186.61M | -117.02M | -509.34M | -322.32M | -170.52M | - | 28.32M | -95.90M | -126.23M | -250.64M |
| Diluted EPS | - | - | - | - | - | - | - | - | -2.09 | -1.02 | - | 0.14 | -0.39 | -0.47 | -1.37 |
| R&D Expense | 70.23M | 64.03M | 48.14M | 58.98M | 147.48M | 112.14M | 143.21M | 404.59M | - | - | - | - | 48.61M | 53.07M | 41.33M |
Compounded Sales Growth
| 5 Years: | -28.87% |
| 1 Year: | 1,633.90% |
Compounded Profit Growth
| 5 Years: | -328.38% |
| 1 Year: | - |
Stock Price Performance
| 1 Year: | +228.79% |
| 6 Months: | +18.26% |
| 3 Months: | +14.51% |
| 1 Month: | +5.34% |
Balance Sheet (Annual)
Figures in USD.
| Metric | Dec 2010 | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | - | - | 151.65M | 469.47M | 576.27M | 982.05M | 949.07M | 846.85M | 716.18M | 455.76M | 314.59M | - | 215.98M | 151.04M | 145.27M | 155.50M |
| Current Assets | - | - | - | - | - | - | - | - | - | - | - | - | 118.16M | 68.75M | 102.41M | 115.23M |
| Cash & Equivalents | 17.37M | 19.63M | 10.40M | 49.51M | 27.47M | 135.78M | 62.61M | 68.11M | 96.88M | 65.79M | 51.79M | - | 4.86M | 7.58M | 29.52M | 30.23M |
| Inventory | - | - | - | - | - | - | - | - | - | - | - | 326.00K | 287.00K | - | 0 | 9.58M |
| Receivables | - | - | - | - | - | - | - | - | - | - | - | - | 978.00K | 902.00K | 926.00K | 3.92M |
| Total Liabilities | - | - | 66.54M | 88.13M | 166.98M | 277.16M | 379.82M | 300.31M | 337.45M | 384.05M | 247.41M | - | 89.72M | 32.55M | 106.75M | 134.59M |
| Current Liabilities | - | - | 16.72M | 19.83M | 47.48M | 75.90M | 94.61M | 80.17M | 61.56M | 122.91M | 42.13M | - | 78.64M | 22.98M | 21.52M | 37.31M |
| Long Term Debt | - | - | - | 1.65M | 8.69M | 7.60M | 7.56M | 7.54M | 211.22M | 186.32M | 171.52M | 179.88M | - | - | - | 93.17M |
| Total Debt | - | - | - | - | - | - | - | - | - | - | - | - | 51.42M | 7.10M | 5.50M | 98.29M |
| Total Equity | - | - | -321.55M | 366.72M | 384.76M | 694.08M | 560.24M | 533.63M | 362.86M | 71.71M | 67.17M | - | 126.26M | 118.50M | 38.51M | 20.91M |
| Shares Outstanding | - | - | - | - | - | - | - | - | - | - | - | - | 208.15M | 256.40M | 292.87M | 353.91M |
Cash Flows (Annual)
Figures in USD.
| Metric | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -81.76M | -61.53M | -53.68M | -19.86M | 35.67M | -48.99M | -103.72M | -124.24M | -135.93M | -77.02M | - | -65.05M | -66.93M | -68.17M | -87.83M |
| Investing Cash Flow | -64.10M | -23.64M | -223.66M | -26.03M | -259.25M | -28.39M | 104.33M | -151.21M | 86.85M | 27.78M | - | 226.42M | -3.09M | -20.71M | -1.53M |
| Financing Cash Flow | 148.11M | 75.94M | 316.45M | 24.00M | 331.68M | 12.06M | 4.28M | 309.80M | 8.14M | 32.70M | - | -155.29M | 29.59M | 110.58M | 90.05M |
| Capital Expenditure | -13.00M | -7.49M | -1.53M | -6.37M | -12.75M | -31.63M | -46.67M | -41.59M | -37.88M | -7.53M | - | -4.92M | -1.54M | -8.58M | -2.00M |
| Free Cash Flow | -94.76M | -69.02M | -55.21M | -26.23M | 22.92M | -80.62M | -150.39M | -165.83M | -173.81M | -84.55M | - | -69.97M | -68.47M | -76.76M | -89.83M |
| Net Change in Cash | - | - | - | - | - | - | - | - | - | - | - | 6.08M | -40.43M | 21.70M | 682.00K |
Ratios (Annual)
Figures in %.
| Metric | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | - | - | - | - | - | 76.4% | 1.7% | -8.7% | 50.2% |
| Operating Margin % | - | - | - | - | - | -65.6% | -62.8% | -334.4% | - | - | - | -277.3% | -1,428.5% | -2,412.9% | -1,100.8% |
| Net Margin % | - | - | - | - | - | -97.7% | -53.3% | -336.9% | -355.3% | -533.0% | - | 105.2% | -1,540.6% | -3,216.2% | -2,588.2% |
| ROE % | - | 25.5% | -10.6% | -21.3% | -12.2% | -33.3% | -21.9% | -140.4% | -449.5% | -253.8% | - | 22.4% | -80.9% | -327.8% | -1,198.6% |
| ROCE % | - | -55.7% | -12.9% | -13.2% | -16.2% | -14.6% | -18.0% | -77.2% | - | - | - | -54.3% | -69.4% | -76.5% | -90.2% |
Shareholding Pattern
Top Institutional Holders
| # | Holder | % Held | Shares | Value |
|---|---|---|---|---|
| 1 | Patient Capital Management, LLC | 5.00% | 17.82M | $77.33M |
| 2 | Blackrock Inc. | 4.27% | 15.22M | $66.07M |
| 3 | State Street Corporation | 3.05% | 10.89M | $47.26M |
| 4 | Vanguard Capital Management LLC | 2.01% | 7.15M | $31.03M |
| 5 | Diametric Capital, Lp | 1.91% | 6.80M | $29.52M |
| 6 | Point72 Asset Management, L.P. | 1.86% | 6.64M | $28.84M |
| 7 | Tang Capital Management, LLC | 1.80% | 6.42M | $27.85M |
| 8 | Geode Capital Management, LLC | 1.29% | 4.61M | $20.02M |
| 9 | Occam Crest Management LP | 1.20% | 4.27M | $18.53M |
| 10 | Iridian Asset Management LLC | 1.01% | 3.59M | $15.59M |
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
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