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Pacific Biosciences of California, Inc. PACB R2KR3KPHARMA

Healthcare · Medical Devices · United States
https://www.pacb.com
Company Profile ↓
$1.35
+5.47% 1Y
Mkt Cap$419.31M
P/E-3.21
P/B148.12
52W High$2.67
52W Low$1.11
Book Value$0.01
EPS (TTM)$-0.42

Company Overview

Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solutions to resolve genetically complex problems. The company provides sequencing systems; consumable products, including single molecule real-time (SMRT) technology; long-read sequencing; and various reagent kits designed for specific workflow, such as preparation kit to convert DNA into SMRTbell double-stranded DNA library formats, including molecular biology reagents, such as ligase, buffers, and exonucleases. It also offers binding kits, such as modified DNA polymerase used to bind SMRTbell libraries to the polymerase in preparation for sequencing; and sequencing kits comprise reagents required for on-instrument, real-time sequencing, including the phospholinked nucleotides. In addition, the company provides Revio, Vega, and Sequel instruments which conduct, monitor, and analyze single-molecule biochemical reactions on SMRT cell microchips; short-read sequencing; and onso instrument. It serves academic and governmental research institutions, commercial testing and service laboratories, genome centers, public health labs, hospitals and clinical research institutes, contract research organizations, pharmaceutical companies, and agricultural companies. The company markets its products through a sales force and distribution partners in Australia, certain parts of Asia, Europe, the Middle East, Africa, Central America, and South America. It has a collaboration with DNAstack Inc. to provide federated dataset of HiFi whole genome sequencing data. The company was formerly known as Nanofluidics, Inc. and changed its name to Pacific Biosciences of California, Inc. in 2005. Pacific Biosciences of California, Inc. was incorporated in 2000 and is headquartered in Menlo Park, California.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 55.6% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $160.00M (+3.9% YoY); net profit $-546.38M.
  • Trailing 12 Months Year-on-year growth — revenue -1.9%.
  • 5-Year Trend Long-term compounding — revenue CAGR 55.6%.

Growth & Price Performance

Compounded Sales Growth

5 Years:55.64%
1 Year:-1.90%

Stock Price Performance

1 Year:+5.47%
6 Months:-2.17%
3 Months:-6.90%
1 Month:+15.38%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 15% of range
$1.11 $2.67
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)50.55 · Neutral
Price Performance
1M+15.38%
3M-6.90%
6M-2.17%
1Y+5.47%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 55.6% over 5 years.

CONS

  • Trading 49.4% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-3.21
Industry PE
25.17
Forward P/E
-3.39
PEG Ratio
-
Book Value
$0.01
Price to Book
148.12
P/S
2.31
EV/EBITDA
-1.62
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
55.64%
Profit 5Y
-
Revenue (YoY)
-1.90%
Earnings (YoY)
-

Profitability & Returns

ROCE
-77.87%
ROE
-
ROA
-41.90%
Profit Margin
-82.49%
Op Margin
-
Gross Margin
29.44%
EPS (Latest Qtr)
$-0.14
EPS (TTM)
$-0.42

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
5.41
Current Ratio
6.87
Debt
$706.13M
Total Assets
$751.85M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
8.91%
Chg in Prom Hold
-0.01%
FII / Inst Holding
55.28%
Chg in FII Hold
-0.00%

Financial Snapshot

Enterprise Value
$419.31M
Total Revenue (TTM)
$159.27M
EBITDA
$-515.00M
Free Cash Flow
$-113.92M
Operating Cash Flow
$-111.21M
Shares Outstanding
310.60M
Gross Margin
29.44%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 PACB Pacific Biosciences of California, Inc. R2KR3KPHARMA 1.35 -3.21 $419.31M 0.00% -77.87% - 55.64% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue --------24.91M20.07M23.55M-19.36M21.58M18.16M-16.43M24.62M21.91M-15.60M19.08M19.08M29.00M30.61M34.89M33.17M35.47M32.31M38.90M47.57M55.69M38.81M36.01M39.97M37.15M39.77M38.44M37.18M39.01M
Gross Profit 5.93M14.51M6.55M26.47M9.50M10.64M12.64M11.37M8.94M8.00M8.23M9.49M7.30M8.86M3.19M5.75M5.12M9.61M6.91M12.93M7.49M6.61M7.06M12.98M13.75M15.36M14.15M16.19M13.55M9.76M15.55M17.90M11.28M5.94M10.00M-1.37M14.68M15.90M12.84M12.64M
Operating Income -19.33M-11.36M2.61M-1.06M-18.57M-18.07M-16.73M-17.87M-23.30M-24.39M-21.57M-20.53M-23.95M-21.75M-24.67M-30.62M-30.13M-24.38M-28.11M-17.92M-32.71M-23.52M-24.18M-33.71M-37.57M-74.48M-77.52M-67.97M-74.62M-91.25M-73.17M-82.49M-81.36M-175.85M-64.08M-428.93M-44.85M-38.88M-8.36M-44.61M
Net Income -20.17M-11.94M1.82M-1.41M-19.35M-18.50M-17.49M-19.03M-23.87M-25.54M-22.02M-20.76M-24.18M-22.54M-25.04M-30.80M-30.32M-24.60M-29.12M-91.00K1.26M-23.09M-23.71M-87.44M-41.00M16.54M-81.50M-71.39M-76.97M-88.02M-69.83M-66.87M-78.18M-173.32M-60.73M-426.07M-41.93M-38.00M-8.28M-44.74M
Diluted EPS --0.02----0.19----------0.20---0.01-0.15-0.14-0.45-0.210.08-0.37-0.32-0.34-0.36-0.28-0.26-0.29-0.64-0.22-1.44-0.14-0.13-0.03-0.14
R&D Expense 14.48M15.04M16.16M-16.36M17.52M17.48M-16.97M16.88M15.84M-16.31M15.66M14.36M-15.48M14.91M14.96M-15.25M15.01M16.47M20.55M22.27M27.51M52.94M50.35M47.09M48.94M46.17M47.51M43.45M38.48M25.52M29.05M22.53M22.85M19.61M23.02M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 135.00K1.67M33.86M25.98M28.18M60.59M92.78M90.71M93.47M78.63M90.89M78.89M130.51M128.30M200.52M154.01M160.00M
Gross Profit 135.00K1.67M13.03M940.00K6.42M23.40M53.45M44.16M34.66M25.10M34.58M32.57M58.86M49.03M52.78M37.28M45.78M
Operating Income ---109.76M-94.34M-77.54M-62.85M-29.13M-71.24M-89.78M-100.99M-100.55M-104.39M-210.44M-307.20M-334.47M-474.31M-553.86M
Net Income -87.70M-140.17M-109.39M-94.47M-79.29M-66.16M-31.70M-74.38M-92.19M-102.56M-84.13M29.40M-181.22M-314.25M-306.74M-309.85M-546.38M
Diluted EPS ----------0.76-0.550.17-0.89-1.40-1.21-1.59-1.82
R&D Expense 75.88M111.82M76.08M47.62M45.22M48.23M60.44M67.62M65.32M62.59M59.63M64.15M112.90M193.00M187.17M134.92M97.31M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2008Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --305.75M218.32M129.68M136.19M124.39M131.11M137.88M144.08M170.28M147.99M413.98M2.01B1.77B1.75B1.26B784.08M
Total Equity -93.39M-177.12M279.87M191.46M109.38M69.18M54.95M73.54M84.67M86.10M114.06M54.92M335.49M790.99M562.90M701.30M506.59M5.35M
Cash & Equivalents 78.46M89.23M147.65M58.87M46.54M26.36M36.45M33.63M16.77M16.51M18.84M29.63M81.61M460.73M325.09M179.91M55.37M63.71M
Long Term Debt --2.93M2.79M2.61M13.35M14.12M-16.11M13.63M14.66M15.87M-896.07M896.68M---
Total Liabilities --25.88M26.85M20.30M67.00M69.44M57.57M53.22M57.98M56.21M93.07M78.49M1.22B1.20B1.04B753.85M778.73M
Current Liabilities --20.84M19.38M14.74M22.55M31.49M38.18M33.77M28.64M26.88M49.15M38.50M71.71M263.33M95.03M66.30M72.83M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -74.84M-122.00M-102.97M-76.82M-29.83M---67.93M-67.52M-66.43M-78.31M19.50M-111.18M-263.21M-259.17M-206.06M-111.21M
Investing Cash Flow 18.59M-138.25M6.45M61.79M-33.12M---14.86M-1.55M-38.41M62.05M-219.32M-678.53M116.08M4.60M124.00M115.45M
Financing Cash Flow 67.01M318.66M7.74M2.71M42.77M--65.93M68.81M107.18M26.55M251.84M1.17B9.62M108.89M-42.99M3.43M
Capital Expenditure -5.18M-5.26M-9.28M-1.70M-909.00K-1.61M-3.01M-8.21M-10.43M-1.85M-2.84M-1.04M-5.93M-16.75M-8.84M-6.19M-2.71M
Free Cash Flow -80.02M-127.25M-112.26M-78.53M-30.74M---76.14M-77.95M-68.28M-81.15M18.46M-117.11M-279.96M-268.02M-212.25M-113.92M
Share Buybacks 8.00K----------------

Ratios (Annual)

Figures in %.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % 100.0%100.0%38.5%3.6%22.8%38.6%57.6%48.7%37.1%31.9%38.0%41.3%45.1%38.2%26.3%24.2%28.6%
Operating Margin % ---324.1%-363.1%-275.2%-103.7%-31.4%-78.5%-96.1%-128.4%-110.6%-132.3%-161.2%-239.4%-166.8%-308.0%-346.2%
Net Margin % -64,965.2%-8,373.1%-323.0%-363.6%-281.4%-109.2%-34.2%-82.0%-98.6%-130.4%-92.6%37.3%-138.9%-244.9%-153.0%-201.2%-341.5%
ROE % 49.5%-50.1%-57.1%-86.4%-114.6%-120.4%-43.1%-87.8%-107.1%-89.9%-153.2%8.8%-22.9%-55.8%-43.7%-61.2%-10,214.5%
ROCE % ---55.2%-82.1%-68.2%-67.7%-31.4%-68.4%-77.8%-70.4%-101.7%-27.8%-10.9%-20.4%-20.3%-39.7%-77.9%

Shareholding Pattern

Insiders
8.91%
Institutions
55.28%
Public Float
60.69%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 10.40% 32.34M $45.28M
2 ARK Investment Management, LLC 9.58% 29.78M $41.69M
3 Softbank Group Corporation 6.58% 20.45M $28.63M
4 Vanguard Capital Management LLC 4.31% 13.40M $18.76M
5 Geode Capital Management, LLC 2.45% 7.61M $10.65M
6 Sumitomo Mitsui Trust Group, Inc. 1.93% 6.01M $8.41M
7 Amova Asset Management Americas Inc 1.93% 6.01M $8.41M
8 State Street Corporation 1.92% 5.96M $8.35M
9 Point72 Asset Management, L.P. 1.54% 4.79M $6.70M
10 Two Sigma Investments, LP 1.36% 4.24M $5.94M

Analyst View

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Latest News

Recent headlines for PACB

Google News Wed, 02 Sep 2026

3 Reasons to Sell PACB and 1 Stock to Buy Instead - Yahoo Finance

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Google News hu, 06 Aug 2026

Pacific Biosciences: It's Only Getting Worse (NASDAQ:PACB) - Seeking Alpha

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Google News Fri, 04 Sep 2026

Pacific Biosciences (PACB) Up 11.6% Since Last Earnings Report: Can It Continue? - Eastern Progress

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Google News Wed, 29 Jul 2026

1 Russell 2000 Stock on Our Watchlist and 2 That Underwhelm - StockStory

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Google News hu, 16 Jul 2026

$PACB stock is down 5% today. Here's what we see in our data. - quiverquant.com

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Google News ue, 26 May 2026

PACB - Finviz

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PACB — Frequently Asked Questions

What is the current share price of Pacific Biosciences of California, Inc. (PACB)?

As of 2026-09-07 16:24 PDT, Pacific Biosciences of California, Inc. (PACB) trades at $1.35 on NasdaqGS. Its 52-week range is $1.11 to $2.67.

What is the market capitalisation of PACB?

Pacific Biosciences of California, Inc. (PACB) has a market capitalisation of $419.31M on NasdaqGS.

What is the P/E ratio of PACB?

PACB trades at a trailing price-to-earnings (P/E) ratio of -3.21. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 148.12.

Is PACB a good stock to buy?

This page provides a data-driven analysis of Pacific Biosciences of California, Inc. (PACB), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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