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$8.42
+62.24% 1Y
Mkt Cap$38.54M
P/E-1.02
P/B2.05
52W High$14.27
52W Low$1.60
Book Value$2.99
EPS (TTM)$-8.28

Company Overview

NextCure, Inc., a clinical-stage biopharmaceutical company, engages in advancing medicines to treat cancer. The company's product candidate is the LNCB74, a B7-H4 targeted ADC to kill tumors. It also develops NC410, a fusion protein of LAIR-2, that is designed to block immune suppression mediated by LAIR-1; NC525, a novel LAIR-1 antibody that targets acute myeloid leukemia, blast cells, and leukemic stem cells; NC181 a humanized antibody targeting ApoE4 for the treatment of Alzheimer's disease; and NC605 an antibody that targets Siglec-15, as well as chronic bone diseases, such as osteoarthritis and non-union fractures. The company also develop SIM0505, a novel antibody-drug conjugate (ADC) targeting CDH6 (cadherin-6 or K-cadherin) for the treatment of solid tumors. The company was incorporated in 2015 and is headquartered in Baltimore, Maryland.

Why Investors Should Care

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.38.

Growth & Price Performance

Stock Price Performance

1 Year:+62.24%
6 Months:-32.69%
3 Months:+201.79%
1 Month:+44.18%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Mixed
52-Week Range 54% of range
$1.60 $14.27
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMABelow
  • RSI (14)69.41 · Neutral
Price Performance
1M+44.18%
3M+201.79%
6M-32.69%
1Y+62.24%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 41.0% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-1.02
Industry PE
24.83
Forward P/E
-1.43
PEG Ratio
-
Book Value
$2.99
Price to Book
2.05
P/S
-
EV/EBITDA
-0.28
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-145.43%
ROE
-
ROA
-69.02%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-2.80
EPS (TTM)
$-8.28

Balance Sheet & Liquidity

Debt/Equity
0.38
Quick Ratio
3.15
Current Ratio
3.47
Debt
$4.67M
Total Assets
$22.62M
Current Assets
$31.74M
Working Capital
$33.18M

Ownership

Promoter Holding
8.64%
Chg in Prom Hold
-4.50%
FII / Inst Holding
52.74%
Chg in FII Hold
15.78%

Financial Snapshot

Enterprise Value
$38.54M
Total Revenue (TTM)
$0
EBITDA
$-37.37M
Free Cash Flow
$-23.10M
Operating Cash Flow
$-36.98M
Shares Outstanding
4.58M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 NXTC NextCure, Inc. PHARMA 8.42 -1.02 $38.54M 0.00% -145.43% - - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026Jun 2026
Revenue ---1.36M1.40M1.58M22.38M---------------00000-
Cost of Revenue ----------------------------
Gross Profit ----------------------------
Operating Expenses ----------------------11.62M27.29M8.95M9.76M10.11M-
Operating Income -5.01M-5.30M-5.82M-6.82M-8.96M-9.70M8.21M-15.80M-17.40M-17.23M-17.95M-18.51M-20.77M-18.13M-19.24M-17.07M-19.16M-15.62M-18.30M-16.49M-12.49M--11.62M-27.29M-8.95M-9.76M-10.11M-15.09M
EBITDA -----------------------10.97M-26.66M-8.41M-9.39M-9.82M-
Interest Expense ----------------------------
Pretax Income -----------------------10.98M-26.81M-8.62M-9.44M-9.80M-
Tax Provision ----------------------------
Net Income -5.00M-5.23M-5.71M-6.16M-8.22M-8.43M9.73M-14.51M-16.37M-16.53M-17.99M-17.93M-20.60M-17.92M-18.91M-16.10M-17.86M-14.30M-17.11M-15.40M-11.54M--10.98M-26.81M-8.62M-9.44M-9.80M-14.89M
Diluted EPS ----4.46--0.33--0.59-0.60-0.65-0.65-0.74-0.65-0.68-0.58-0.64-0.51-0.61-6.61-4.95--4.70-11.29-3.22--1.87-2.80
R&D Expense 4.21M4.43M4.89M6.51M7.64M8.66M10.58M11.13M12.74M12.39M11.95M13.60M15.02M12.82M13.53M11.65M13.45M11.01M11.40M12.42M8.77M-7.90M24.09M6.14M-6.83M7.42M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -6.35M22.38M-0000
Cost of Revenue --------
Gross Profit --------
Operating Expenses ----75.91M67.64M57.21M57.62M
Operating Income -23.20M-37.48M-41.23M-70.77M-75.91M-67.64M-57.21M-57.62M
EBITDA -----71.78M-63.95M-54.34M-55.43M
Interest Expense --------
Pretax Income -----74.73M-62.72M-55.65M-55.84M
Tax Provision --------
Net Income -22.80M-33.74M-36.60M-69.39M-74.73M-62.72M-55.65M-55.84M
Diluted EPS ---1.33-2.51-32.28-27.00-23.88-19.65
R&D Expense 19.79M34.22M46.55M50.19M54.20M47.93M41.49M44.92M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -147.63M356.17M306.64M-184.16M128.04M80.86M50.18M
Current Assets -----163.98M112.72M71.81M43.75M
Cash & Equivalents -135.17M34.09M32.77M-26.63M13.08M27.73M25.98M
Inventory ---------
Receivables ---------
Total Liabilities -32.35M34.68M12.92M-16.63M13.62M15.39M15.24M
Current Liabilities -10.30M15.04M10.32M-9.13M6.88M9.57M10.57M
Long Term Debt -73.00K3.33M1.81M-----
Total Debt -----7.12M6.61M5.95M5.15M
Total Equity -24.41M-46.94M321.48M293.72M-167.53M114.42M65.47M34.94M
Shares Outstanding -----2.31M2.33M2.33M3.51M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow 7.99M-35.62M-44.95M--53.89M-52.97M-40.80M-49.61M
Investing Cash Flow -3.06M-303.92M43.52M-67.98M39.27M55.31M25.56M
Financing Cash Flow 121.42M243.04M-1.42M-200.00K154.00K144.00K22.31M
Capital Expenditure -3.06M-3.37M-7.13M-2.36M-2.12M-820.00K-474.00K-
Free Cash Flow 4.93M-38.99M-52.09M--56.00M-53.79M-41.28M-49.61M
Net Change in Cash ----14.29M-13.55M14.64M-1.75M

Ratios (Annual)

Figures in %.

Metric Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % --------
Operating Margin % --590.5%-184.2%-----
Net Margin % --531.5%-163.6%-----
ROE % 48.6%-10.5%-12.5%--44.6%-54.8%-85.0%-159.8%
ROCE % -16.9%-11.0%-13.9%--43.4%-55.8%-80.2%-145.4%

Shareholding Pattern

Insiders
8.64%
Institutions
52.74%
Public Float
57.73%

Top Institutional Holders

#Holder% HeldSharesValue
1 Ikarian Capital, LLC 7.98% 288.30K $1.76M
2 Adage Capital Partners GP L.L.C. 7.67% 277.20K $1.70M
3 Sofinnova Investments, Inc. 6.16% 222.65K $1.36M
4 Renaissance Technologies, LLC 4.74% 171.20K $1.05M
5 Vanguard Capital Management LLC 4.34% 156.84K $959.87K
6 Millennium Management Llc 2.44% 88.11K $539.25K
7 Boothbay Fund Management, LLC 2.34% 84.69K $518.28K
8 Squadron Capital Management LLC 1.78% 64.46K $394.52K
9 Verdad Advisers, LP 1.67% 60.45K $369.96K
10 Pfizer Inc 1.23% 44.35K $271.40K

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for NXTC

Yahoo Finance hu, 06 Aug 2026

NextCure Provides Business Update and Reports Second Quarter 2026 Financial Results

Announced Proposed Merger with Avere TherapeuticsPreserving Capital in Support of Merger Closing; Continuing Clinical Transition and Legacy Asset Activities BELTSVILLE, Md., Aug. 06, 2026 (GLOBE NEWSWIRE) -- NextCure, Inc. (Nasdaq: NXTC), a…

Yahoo Finance ue, 14 Jul 2026

Fresh off buyout, Akero execs reunite to advance long-acting psoriasis pill

Set to go public via a reverse merger, Avere has licensed from a prolific Chinese drugmaker rights to a potential threat to medicines like Skyrizi and Icotyde.

Yahoo Finance Mon, 01 Jun 2026

NextCure Presents Positive SIM0505 Phase 1 Dose Escalation Data in Patients with Gynecologic Cancers at ASCO 2026

55% ORR in gynecologic cancers with 52.9% in ovarian and 66.7% in USC at 12 weeks by best response per RECIST 1.1 within the therapeutic dose range (4.8 – 8.0 mg/kg)Favorable safety and tolerability in heavily pretreated population supports…

Yahoo Finance hu, 07 May 2026

NextCure Provides Business Update and Reports First Quarter 2026 Financial Results

SIM0505/CDH6 ADC dose optimization initiated in gynecologic cancersSIM0505 Phase 1 dose escalation study data to be presented at ASCO 2026 LNCB74 Phase 1 dose escalation trial update planned in second half of 2026 BELTSVILLE, Md., May 07, 2…

Yahoo Finance Mon, 04 May 2026

NextCure and Simcere Zaiming Initiate Dose Optimization for SIM0505 (CDH6 ADC) in Gynecologic Cancers

Dose optimization will initially be focused on evaluating SIM0505 in patients with platinum-resistant ovarian cancer (PROC) Phase 1 data readout to be presented at ASCO 2026 BELTSVILLE, Md., May 04, 2026 (GLOBE NEWSWIRE) -- NextCure, Inc. (…

Yahoo Finance ue, 21 Apr 2026

NextCure and Simcere’s SIM0505 (CDH6 ADC) Phase 1 Data to be Presented at ASCO 2026

Poster to be presented at the American Society for Clinical Oncology on Monday, June 1, 2026BELTSVILLE, Md., April 21, 2026 (GLOBE NEWSWIRE) -- NextCure, Inc. (Nasdaq: NXTC), a clinical-stage biopharmaceutical company committed to discoveri…

NXTC — Frequently Asked Questions

What is the current share price of NextCure, Inc. (NXTC)?

As of 2026-09-19 21:16 PDT, NextCure, Inc. (NXTC) trades at $8.42 on NasdaqGS. Its 52-week range is $1.60 to $14.27.

What is the market capitalisation of NXTC?

NextCure, Inc. (NXTC) has a market capitalisation of $38.54M on NasdaqGS.

What is the P/E ratio of NXTC?

NXTC trades at a trailing price-to-earnings (P/E) ratio of -1.02. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 2.05.

Is NXTC a good stock to buy?

This page provides a data-driven analysis of NextCure, Inc. (NXTC), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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