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Nurix Therapeutics, Inc. NRIX R2K

Healthcare · Biotechnology · United States
https://www.nurixtx.com
Company Profile ↓
$23.85
+87.94% 1Y
Mkt Cap$2.48B
P/E-6.89
P/B5.03
52W High$24.69
52W Low$8.24
Book Value$4.65
EPS (TTM)$-3.46

Company Overview

Nurix Therapeutics, Inc., a clinical stage biopharmaceutical company, focuses on the discovery, development, and commercialization of small molecule and antibody therapies for the treatment of cancer, inflammatory conditions, and other diseases. The company develops NX-5948, an orally bioavailable BTK degrader, that is in Phase 2 clinical trials for the treatment of relapsed or refractory B-cell malignancies and autoimmune diseases; NX-2127, an orally bioavailable Bruton's tyrosine kinase (BTK) degrader, that is in Phase Phase 1a/1b clinical trials for the treatment of relapsed or refractory B-cell malignancies; and NX-1607, an orally bioavailable Casitas B-lineage lymphoma proto-oncogene-B (CBL-B) inhibitor, that is in Phase 1a/1b clinical trials to treat immuno-oncology indications. It is also developing NX-0479/GS-6791, a IRAK4 degrader for the treatment of rheumatoid arthritis and other inflammatory diseases. The company has a strategic collaboration agreement with Gilead Sciences, Inc. (Gilead), Sanofi S.A. (Sanofi), and Pfizer Inc. (Pfizer) for co-development and co-commercialization for multiple drug candidates. The company was formerly known as Nurix Inc. and changed its name to Nurix Therapeutics, Inc. in October 2018. Nurix Therapeutics, Inc. was incorporated in 2009 and is headquartered in Brisbane, California.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 18.0% CAGR over the past five years.

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.14.

Recent Developments

  • Nov 2025 Revenue of $83.98M (+54.0% YoY); net profit $-264.46M.
  • Trailing 12 Months Year-on-year growth — revenue -79.5%.
  • 5-Year Trend Long-term compounding — revenue CAGR 18.0%.

Growth & Price Performance

Compounded Sales Growth

5 Years:18.00%
1 Year:-79.50%

Stock Price Performance

1 Year:+87.94%
6 Months:+29.76%
3 Months:+46.32%
1 Month:+40.71%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 95% of range
$8.24 $24.69
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)67.77 · Neutral
Price Performance
1M+40.71%
3M+46.32%
6M+29.76%
1Y+87.94%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 18.0% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-6.89
Industry PE
25.88
Forward P/E
-10.78
PEG Ratio
-
Book Value
$4.65
Price to Book
5.03
P/S
66.05
EV/EBITDA
-5.66
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
18.00%
Profit 5Y
-
Revenue (YoY)
-79.50%
Earnings (YoY)
-

Profitability & Returns

ROCE
-47.48%
ROE
-80.30%
ROA
-40.06%
Profit Margin
0.00%
Op Margin
-
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.79
EPS (TTM)
$-3.46

Balance Sheet & Liquidity

Debt/Equity
0.14
Quick Ratio
6.18
Current Ratio
6.34
Debt
$58.14M
Total Assets
$636.13M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
1.08%
Chg in Prom Hold
-0.00%
FII / Inst Holding
114.38%
Chg in FII Hold
-0.26%

Financial Snapshot

Enterprise Value
$2.48B
Total Revenue (TTM)
$36.77M
EBITDA
$-353.18M
Free Cash Flow
$-164.64M
Operating Cash Flow
$-293.70M
Shares Outstanding
103.78M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 NRIX Nurix Therapeutics, Inc. R2K 23.85 -6.89 $2.48B 0.00% -47.48% -80.30% 18.00% -
2 LLY Eli Lilly and Company SPX 1,156.63 41.13 $1.03T 0.60% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 247.02 28.66 $594.63B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.11 119.08 $431.29B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 418.52 31.54 $380.08B 2.18% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 123.61 34.82 $305.29B 2.82% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 168.37 26.10 $261.12B 1.87% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 535.29 29.40 $198.93B 0.35% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 358.32 24.92 $193.39B 2.80% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Feb 2019May 2019Aug 2019Nov 2019Feb 2020May 2020Aug 2020Nov 2020Feb 2021May 2021Aug 2021Feb 2022May 2022Aug 2022Feb 2023May 2023Aug 2023Feb 2024May 2024Aug 2024Feb 2025May 2025Aug 2025Feb 2026
Revenue ---------------30.68M18.47M16.59M12.09M12.59M18.45M44.06M7.89M6.25M
Operating Income ---2.61M--12.55M-13.23M-19.19M--24.52M-26.41M-29.00M-42.74M-45.72M-46.72M-42.95M-26.77M-40.01M-45.22M-48.54M-54.61M-62.86M-48.32M-91.39M-92.50M
Net Income -2.69M-3.07M-2.43M-13.52M-12.39M7.58M-18.52M-19.91M-24.27M-26.38M-28.84M-42.53M-45.40M-45.71M-40.73M-24.28M-36.98M-41.52M-44.55M-48.96M-56.35M-43.46M-86.42M-87.17M
Diluted EPS -----0.00-1.09---0.60-0.65-0.95-1.01-0.90-0.75-0.45-0.68-0.76-0.71-0.67-0.67-0.52-1.03-0.79
R&D Expense --11.01M-12.97M14.14M18.94M-23.00M25.99M30.91M43.14M47.49M47.76M45.82M45.76M47.86M50.01M48.92M55.48M69.66M78.10M86.12M84.14M

Profit & Loss (Annual)

Figures in USD.

Metric Nov 2019Nov 2020Nov 2021Nov 2022Nov 2023Nov 2024Nov 2025
Revenue 31.11M17.82M29.75M38.63M76.99M54.55M83.98M
Operating Income -22.24M-64.98M-117.89M-183.87M-155.06M-213.03M-285.67M
Net Income -21.70M-43.24M-117.19M-180.36M-143.95M-193.57M-264.46M
Diluted EPS ---2.73-3.71-2.65-2.88-3.05
R&D Expense 45.02M66.49M116.43M184.50M189.15M221.63M316.90M

Balance Sheet (Annual)

Figures in USD.

Metric Nov 2018Nov 2019Nov 2020Nov 2021Nov 2022Nov 2023Nov 2024Nov 2025
Total Assets -44.05M396.34M476.77M416.76M355.60M669.34M688.13M
Total Equity -36.85M-57.71M290.27M342.30M303.70M200.49M526.99M538.75M
Cash & Equivalents -34.82M119.36M80.51M64.47M54.63M110.00M246.96M
Total Liabilities -53.57M106.07M134.47M113.06M155.10M142.35M149.39M
Current Liabilities -16.14M44.54M66.26M70.66M86.96M95.85M86.47M

Cash Flows (Annual)

Figures in USD.

Metric Nov 2019Nov 2020Nov 2021Nov 2022Nov 2023Nov 2024Nov 2025
Operating Cash Flow 601.00K-80.00K-84.36M-159.81M-81.36M-172.58M-249.47M
Investing Cash Flow 8.50M-254.40M-108.25M27.20M68.30M-257.71M147.85M
Financing Cash Flow 126.00K339.02M153.88M117.19M3.22M485.67M238.64M
Capital Expenditure -1.65M-4.55M-5.66M-12.24M-8.40M-9.27M-14.00M
Free Cash Flow -1.05M-4.63M-90.03M-172.05M-89.77M-181.86M-263.47M

Ratios (Annual)

Figures in %.

Metric Nov 2019Nov 2020Nov 2021Nov 2022Nov 2023Nov 2024Nov 2025
Gross Margin % -------
Operating Margin % -71.5%-364.7%-396.3%-476.0%-201.4%-390.5%-340.2%
Net Margin % -69.7%-242.7%-393.9%-466.9%-187.0%-354.9%-314.9%
ROE % 37.6%-14.9%-34.2%-59.4%-71.8%-36.7%-49.1%
ROCE % -79.7%-18.5%-28.7%-53.1%-57.7%-37.1%-47.5%

Shareholding Pattern

Insiders
1.08%
Institutions
114.38%
Public Float
115.64%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 8.60% 8.93M $208.95M
2 Redmile Group, LLC 7.45% 7.73M $181.03M
3 Vestal Point Capital, LP 6.26% 6.50M $152.16M
4 Deep Track Capital, Lp 6.11% 6.35M $148.54M
5 FMR, LLC 5.34% 5.54M $129.72M
6 State Street Corporation 4.95% 5.14M $120.36M
7 Morgan Stanley 4.75% 4.93M $115.46M
8 Baker Bros. Advisors, LP 4.49% 4.66M $109.06M
9 Vanguard Capital Management LLC 4.27% 4.43M $103.64M
10 General Atlantic, L.P. 3.95% 4.10M $96.02M

Analyst View

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Latest News

Recent headlines for NRIX

Google News Sat, 11 Jul 2026

Nurix Therapeutics (NRIX) Stock Looks Pricey After Roche Deal And Weaker Quarter - simplywall.st

<a href="https://news.google.com/rss/articles/CBMi5gFBVV95cUxNWmhxdkpuR25PTXQ0WHpzQkplS2txdzNiSTdBby1OUHNLdExSS0xtNmo3c3BMNWhLZmFWckx5MzYtZlhjdjNLeHp5UDhrMndpdDFVbmlIa3g2MWJseXBjSzhpTGhZVmo5ZkhRYlhFSHJoV0ctVnIxdmFBLVpnaWltQlpISU9OLUpMLXkwM1…

Google News Wed, 01 Jul 2026

Earnings Preview: Nurix Therapeutics, Inc. (NRIX) Q2 Earnings Expected to Decline - Yahoo Finance

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Google News Wed, 15 Jul 2026

Nurix Therapeutics, Inc. (NASDAQ:NRIX) Given Average Rating of "Moderate Buy" by Brokerages - MarketBeat

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Google News Fri, 10 Jul 2026

$NRIX stock is down 9% today. Here's what we see in our data. - Quiver Quantitative

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Google News Mon, 13 Jul 2026

NRIX Maintained by Mizuho -- Price Target Raised to $34.00 - GuruFocus

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Google News Mon, 08 Jun 2026

NRIX Stock Surges Nearly 70% Premarket Today – Roche And Nurix’s Blood Cancer Drug Collaboration Can Tap A $41B Market - Stocktwits

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NRIX — Frequently Asked Questions

What is the current share price of Nurix Therapeutics, Inc. (NRIX)?

As of 2026-07-15 16:51 PDT, Nurix Therapeutics, Inc. (NRIX) trades at $23.85 on NasdaqGM. Its 52-week range is $8.24 to $24.69.

What is the market capitalisation of NRIX?

Nurix Therapeutics, Inc. (NRIX) has a market capitalisation of $2.48B on NasdaqGM.

What is the P/E ratio of NRIX?

NRIX trades at a trailing price-to-earnings (P/E) ratio of -6.89. The industry average P/E is 25.88. Its price-to-book (P/B) ratio is 5.03.

What is the return on equity (ROE) of NRIX?

NRIX has a return on equity (ROE) of -80.30%. Its return on capital employed (ROCE) is -47.48%.

Is NRIX a good stock to buy?

This page provides a data-driven analysis of Nurix Therapeutics, Inc. (NRIX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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