Kymera Therapeutics, Inc. KYMR R2K
Kymera Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. It engages in developing KT-621, an oral STAT6 degrader in Phase 2b clinical trials for moderate to severe atopic dermatitis, asthma, COPD, EoE, CRSwNP, CSU, PN, BP, and others; KT-579, an oral IRF5 degrader in Phase 1 trials for autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, SSc, DM, and others; KT-485/SAR447971, IRAK4 program, which is in Phase II clinical trial for the treatment of immunology-inflammation diseases, including hidradenitis suppurativa and atopic dermatitis; and cyclin-dependent kinase 2 (CDK2) with broad oncology treatment potential, including in breast cancer and other solid tumors. The company has a strategic alliance with Sanofi S.A. for the development of drug candidates targeting IRAK4 outside the oncology and immuno-oncology fields. Kymera Therapeutics, Inc. was incorporated in 2015 and is headquartered in Watertown, Massachusetts.
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Valuation
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Growth (CAGR)
PROS
- In a confirmed uptrend (50-DMA above 200-DMA).
CONS
- Revenue declined at -5.7% CAGR over 5 years.
- Earnings shrank at -33.7% CAGR over 5 years.
* The pros and cons are auto-generated from financial metrics.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth
No fundamental data available for this stock.
Figures from the latest reported periods. CAGR is computed across the displayed window (quarterly CAGR is annualised assuming 4 quarters per year).
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | KYMR Kymera Therapeutics, Inc. R2K | 81.42 | - | $6.70B | - | -18.74% | -27.09% | -5.74% | -33.71% |
| 2 | LLY Eli Lilly and Company SPX | 1,105.00 | 39.21 | $985.37B | 0.63% | 38.44% | 107.46% | 31.69% | 48.96% |
| 3 | JNJ Johnson & Johnson SPX | 225.33 | 26.11 | $542.42B | 2.38% | 23.13% | 26.42% | 5.60% | 14.32% |
| 4 | UNH UnitedHealth Group Incorporated SPX | 380.31 | 28.66 | $345.38B | 2.32% | 9.60% | 12.18% | 11.35% | -15.69% |
| 5 | MRK Merck & Co., Inc. SPX | 118.72 | 33.44 | $293.22B | 2.86% | 20.66% | 18.94% | 3.12% | 7.93% |
| 6 | TMO Thermo Fisher Scientific Inc. SPX | 492.51 | 27.11 | $183.03B | 0.38% | 9.17% | 13.52% | -0.27% | -1.19% |
| 7 | AMGN Amgen Inc. NDXSPX | 336.79 | 23.42 | $181.77B | 2.99% | 18.02% | 101.32% | 11.77% | 5.58% |
| 8 | GILD Gilead Sciences, Inc. NDXSPX | 134.43 | 18.29 | $166.90B | 2.44% | 22.92% | 43.36% | 2.57% | 22.83% |
| 9 | ISRG Intuitive Surgical, Inc. NDXSPXAI | 424.64 | 51.53 | $150.39B | - | 15.96% | 17.23% | 17.39% | 29.26% |
Quarterly Results
Figures in USD.
| Metric | Sep 2019 | Mar 2020 | Jun 2020 | Sep 2020 | Mar 2021 | Jun 2021 | Sep 2021 | Mar 2022 | Jun 2022 | Sep 2022 | Mar 2023 | Jun 2023 | Sep 2023 | Mar 2024 | Jun 2024 | Sep 2024 | Dec 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Dec 2025 | Mar 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | 950.00K | 3.43M | 3.29M | 14.53M | 18.70M | 18.52M | 20.34M | 9.62M | 11.51M | 9.55M | 9.47M | 16.51M | 4.73M | 10.29M | 25.65M | 3.74M | - | 22.10M | 11.48M | 2.76M | 2.87M | 34.37M |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 96.53M | 96.03M | 91.43M | 100.77M | 118.52M |
| Operating Income | -11.86M | -11.25M | -14.19M | -8.08M | -13.17M | -24.73M | -28.64M | -36.93M | -40.81M | -44.88M | -45.33M | -43.38M | -57.51M | -57.83M | -50.92M | -72.12M | - | -74.43M | -84.56M | -88.67M | -97.90M | -84.15M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -63.46M | -74.42M | -79.93M | -84.86M | -67.15M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 72.00K | 108.00K | 98.00K | 90.00K | 61.00K |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -65.58M | -76.61M | -82.17M | -86.98M | -69.23M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Net Income | -11.42M | -10.93M | -13.99M | -7.99M | -13.07M | -24.66M | -28.58M | -36.68M | -40.26M | -43.00M | -40.93M | -38.80M | -52.87M | -48.56M | -42.06M | -62.49M | - | -65.58M | -76.61M | -82.17M | -86.98M | -69.23M |
| Diluted EPS | - | - | - | - | - | -0.55 | -0.56 | -0.71 | -0.78 | -0.79 | -0.70 | -0.67 | -0.90 | -0.69 | -0.58 | -0.82 | - | -0.82 | -0.95 | -0.94 | -0.97 | -0.71 |
| R&D Expense | 11.31M | 12.12M | 13.82M | 15.78M | 25.96M | 35.22M | 38.31M | 35.94M | 41.29M | 43.88M | 42.23M | 45.77M | 48.12M | 48.82M | 59.20M | 60.41M | - | 80.25M | 78.39M | 74.09M | - | 98.16M |
Profit & Loss (Annual)
Figures in USD.
| Metric | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|
| Revenue | 2.93M | 34.03M | 72.83M | 46.83M | 78.59M | 47.07M | 39.21M |
| Cost of Revenue | - | - | - | - | - | - | - |
| Gross Profit | - | - | - | - | - | - | - |
| Operating Expenses | - | - | - | 208.08M | 244.12M | 303.78M | 384.75M |
| Operating Income | -42.20M | -46.30M | -100.53M | -161.26M | -165.53M | -256.71M | -345.54M |
| EBITDA | - | - | - | -151.66M | -143.20M | -216.24M | -302.67M |
| Interest Expense | - | - | - | 176.00K | 196.00K | 249.00K | 370.00K |
| Pretax Income | - | - | - | -154.81M | -146.96M | -223.86M | -311.35M |
| Tax Provision | - | - | - | - | - | - | - |
| Net Income | -41.25M | -45.59M | -100.22M | -154.81M | -146.96M | -223.86M | -311.35M |
| Diluted EPS | - | -3.15 | -2.09 | -2.87 | -2.52 | -2.98 | -3.69 |
| R&D Expense | 37.16M | 62.10M | 137.02M | 164.25M | 189.08M | 240.25M | 316.57M |
Compounded Sales Growth
| 5 Years: | -5.74% |
| 1 Year: | 55.50% |
Compounded Profit Growth
| 5 Years: | -33.71% |
| 1 Year: | - |
Stock Price Performance
| 1 Year: | +174.70% |
| 6 Months: | +23.29% |
| 3 Months: | -10.87% |
| 1 Month: | -0.11% |
Balance Sheet (Annual)
Figures in USD.
| Metric | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|
| Total Assets | - | 116.70M | 487.18M | - | 603.13M | 575.76M | 978.03M | 1.74B |
| Current Assets | - | - | - | - | 419.42M | 405.32M | 510.27M | 871.21M |
| Cash & Equivalents | - | 76.02M | 31.00M | - | 68.39M | 109.97M | 120.26M | 357.01M |
| Inventory | - | - | - | - | - | - | - | - |
| Receivables | - | - | - | 0 | 0 | 15.00M | 0 | - |
| Total Liabilities | - | 82.03M | 203.29M | - | 112.98M | 180.79M | 142.42M | 163.15M |
| Current Liabilities | - | 34.57M | 110.62M | - | 71.34M | 85.69M | 67.77M | 83.21M |
| Long Term Debt | - | - | - | - | - | - | - | - |
| Total Debt | - | - | - | - | 17.34M | 84.67M | 87.76M | 82.25M |
| Total Equity | -34.44M | -74.41M | 283.89M | - | 490.15M | 394.97M | 835.62M | 1.58B |
| Shares Outstanding | - | - | - | - | 55.04M | 55.59M | 64.89M | 81.32M |
Cash Flows (Annual)
Figures in USD.
| Metric | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|
| Operating Cash Flow | 17.91M | 88.13M | - | -153.09M | -102.83M | -194.50M | -232.89M |
| Investing Cash Flow | -16.49M | -422.59M | - | 20.52M | 139.89M | -404.08M | -521.06M |
| Financing Cash Flow | 34.91M | 289.26M | - | 153.00M | 4.19M | 608.85M | 990.71M |
| Capital Expenditure | -532.00K | -9.10M | - | -2.84M | -34.48M | -12.84M | -1.45M |
| Free Cash Flow | 17.37M | 79.03M | - | -155.92M | -137.31M | -207.34M | -234.34M |
| Net Change in Cash | - | - | - | 20.43M | 41.25M | 10.27M | 236.76M |
Ratios (Annual)
Figures in %.
| Metric | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | - |
| Operating Margin % | -1,438.5% | -136.1% | -138.0% | -344.4% | -210.6% | -545.4% | -881.2% |
| Net Margin % | -1,405.8% | -134.0% | -137.6% | -330.6% | -187.0% | -475.6% | -794.0% |
| ROE % | 55.4% | -16.1% | - | -31.6% | -37.2% | -26.8% | -19.7% |
| ROCE % | -51.4% | -12.3% | - | -30.3% | -33.8% | -28.2% | -20.8% |
Shareholding Pattern
Top Institutional Holders
| # | Holder | % Held | Shares | Value |
|---|---|---|---|---|
| 1 | FMR, LLC | 14.22% | 11.70M | $952.61M |
| 2 | Baker Bros. Advisors, LP | 10.52% | 8.66M | $704.87M |
| 3 | Avoro Capital Advisors LLC | 9.09% | 7.47M | $608.59M |
| 4 | Price (T.Rowe) Associates Inc | 7.37% | 6.06M | $493.47M |
| 5 | BVF Inc. | 6.69% | 5.50M | $448.03M |
| 6 | T. Rowe Price Investment Management, Inc. | 6.64% | 5.46M | $444.96M |
| 7 | Blackrock Inc. | 6.15% | 5.06M | $412.06M |
| 8 | Atlas Venture Life Science Advisors, LLC | 5.57% | 4.58M | $372.74M |
| 9 | Wellington Management Group, LLP | 4.73% | 3.89M | $316.70M |
| 10 | Siren, L.L.C. | 3.87% | 3.19M | $259.47M |
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
Latest News
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