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Jade Biosciences, Inc. JBIO R2KR3KPHARMA

Healthcare · Biotechnology · United States
https://jadebiosciences.com
Company Profile ↓
$14.59
+99.05% 1Y
Mkt Cap$927.89M
P/E-13.64
P/B2.45
52W High$26.85
52W Low$6.77
Book Value$6.92
EPS (TTM)$-1.07

Company Overview

Jade Biosciences, Inc. operates as a biotechnology company that develops therapies for inflammation and immunology indications in patients living with autoimmune diseases. It develops JADE101, a monoclonal antibody to block the A PRoliferation Inducing Ligand protein, which is in phase 1 clinical trial. The company also develops JADE201 and JADE-003, which are in preclinical development stage. Jade Biosciences, Inc. has a collaboration agreement with Paragon Therapeutics, Inc. Jade Biosciences, Inc. is based in Waltham, Massachusetts.

Why Investors Should Care

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.32.

Growth & Price Performance

Stock Price Performance

1 Year:+99.05%
6 Months:-41.59%
3 Months:-26.87%
1 Month:-0.95%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 39% of range
$6.77 $26.85
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • Death Cross6d ago
  • RSI (14)44.91 · Neutral
Price Performance
1M-0.95%
3M-26.87%
6M-41.59%
1Y+99.05%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 45.7% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-13.64
Industry PE
25.45
Forward P/E
-5.48
PEG Ratio
-
Book Value
$6.92
Price to Book
2.45
P/S
-
EV/EBITDA
-3.83
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-34.07%
ROE
-38.32%
ROA
-36.43%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.76
EPS (TTM)
$-1.07

Balance Sheet & Liquidity

Debt/Equity
0.32
Quick Ratio
14.61
Current Ratio
14.93
Debt
$1.39M
Total Assets
$472.11M
Current Assets
$348.82M
Working Capital
$332.28M

Ownership

Promoter Holding
0.79%
Chg in Prom Hold
-0.04%
FII / Inst Holding
116.11%
Chg in FII Hold
0.03%

Financial Snapshot

Enterprise Value
$927.89M
Total Revenue (TTM)
-
EBITDA
$-164.70M
Free Cash Flow
$-94.89M
Operating Cash Flow
$-123.51M
Shares Outstanding
63.60M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 JBIO Jade Biosciences, Inc. R2KR3KPHARMA 14.59 -13.64 $927.89M 0.00% -34.07% -38.32% - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,273.46 42.83 $1.14T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 263.81 30.60 $635.76B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 285.64 80.69 $504.76B 2.54% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 418.09 26.85 $375.28B 2.47% 9.74% 14.15% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPXR3KPHARMA 145.27 116.22 $358.41B 2.31% - 6.96% 5.64% 10.01%
7 NVS Novartis AG PHARMA 151.12 22.83 $287.24B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 171.49 25.63 $265.96B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 673.82 36.30 $249.14B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Operating Income --1.62M-2.24M-2.78M-5.77M-6.20M-11.02M-12.21M-14.15M-17.64M-20.34M-21.37M-24.62M-26.16M-15.55M-23.38M-27.78M-27.40M-43.45M-58.92M
Net Income -1.44M-2.20M-2.31M-2.78M-5.78M-6.18M-10.91M-11.99M-13.59M-16.52M-19.02M-19.56M-23.19M-24.77M-16.87M-38.17M-32.13M-25.18M-40.37M-55.77M
Diluted EPS ------0.26-0.45-0.49-0.56-0.67-0.76-0.71-0.83-0.86-5.35-12.10-0.86-0.48-0.57-0.76
R&D Expense -1.47M1.97M2.20M4.33M3.42M7.25M8.36M10.78M13.49M16.03M16.88M20.08M21.25M13.66M20.02M22.55M22.01M36.05M50.06M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Income -8.89M-23.02M-53.24M-81.41M-74.60M-113.54M
Net Income -9.61M-22.96M-51.51M-75.52M-69.63M-127.41M
Diluted EPS --1.87-2.10-2.87-2.44-3.19
R&D Expense 7.94M14.99M38.62M64.22M53.19M93.12M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Jun 2024Dec 2024Dec 2025
Total Assets -4.71M175.36M135.30M127.42M-72.80M349.78M
Current Assets ------69.65M348.82M
Cash & Equivalents -4.57M54.20M22.40M23.49M-69.39M88.44M
Inventory --------
Receivables --------
Total Liabilities -1.77M2.94M8.56M17.96M-119.60M17.26M
Current Liabilities -1.77M2.55M7.78M17.64M-12.00M16.54M
Long Term Debt ------107.60M-
Total Debt ------107.60M724.00K
Total Equity -3.64M-13.34M172.42M126.74M109.46M1.00K-46.80M332.52M
Shares Outstanding ------32.24M49.32M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -7.86M-27.40M-39.12M-56.78M-71.20M-94.69M
Investing Cash Flow --113.43M6.93M11.88M56.03M-247.01M
Financing Cash Flow 8.92M190.46M396.00K46.00M25.43M360.77M
Capital Expenditure --181.00K-195.00K-142.00K--196.00K
Free Cash Flow --27.58M-39.32M-56.92M--94.89M

Ratios (Annual)

Figures in %.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ------
Operating Margin % ------
Net Margin % ------
ROE % 72.0%-13.3%-40.6%-69.0%148.8%-38.3%
ROCE % -302.2%-13.3%-41.7%-74.2%-122.7%-34.1%

Shareholding Pattern

Insiders
0.79%
Institutions
116.11%
Public Float
117.04%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 14.35% 9.13M $131.34M
2 Jupiter Topco LLC 9.86% 6.27M $90.27M
3 Fairmount Funds Management LLC 7.16% 4.55M $65.52M
4 RA Capital Management, L.P. 5.77% 3.67M $52.83M
5 Venrock Adviser, LLC 5.06% 3.22M $46.34M
6 Bellevue Group AG 4.81% 3.06M $44.00M
7 Paradigm Biocapital Advisors LP 4.49% 2.86M $41.12M
8 Blackrock Inc. 4.40% 2.80M $40.31M
9 Franklin Resources, Inc. 4.39% 2.79M $40.18M
10 State Street Corporation 3.67% 2.34M $33.60M

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for JBIO

Google News hu, 22 Oct 2026

JBIO Nov 2026 30.000 call (JBIO261120C00030000) interactive stock chart - Yahoo Finance UK

<a href="https://news.google.com/rss/articles/CBMibkFVX3lxTE1lVlFEQXNVbjN3NS1RSWVmRldwQzFJU1UtaS1rd0lwNHFQU1c5bHZTU21udnFSbUlpMmVBWXd0SEJFZ3V3ejNkLVViV1JOREhLR29ub0NNVVdNb1NNZUdYb1VraUxwUDE1bU9sLVN3?oc=5" target="_blank">JBIO Nov 2026 30.00…

Google News Wed, 21 Oct 2026

About 169,000 Americans have IgA kidney disease. Jade expects its trial to start this quarter. - Stock Titan

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Google News hu, 25 Jun 2026

JBIO Forecast — Price Target — Prediction for 2027 - TradingView

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Google News Wed, 19 Aug 2026

Jade Biosciences: Duration Is The Real Product (NASDAQ:JBIO) - Seeking Alpha

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Google News hu, 22 Oct 2026

JBIO Nov 2026 30.000 call (JBIO261120C00030000) stock historical prices and data - Yahoo Finance UK

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Google News ue, 06 Oct 2026

how InvestingPro’s fair value flagged Jade Biosciences’ 48% decline By Investing.com - Investing.com

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JBIO — Frequently Asked Questions

What is the current share price of Jade Biosciences, Inc. (JBIO)?

As of 2026-10-23 16:27 PDT, Jade Biosciences, Inc. (JBIO) trades at $14.59 on NasdaqCM. Its 52-week range is $6.77 to $26.85.

What is the market capitalisation of JBIO?

Jade Biosciences, Inc. (JBIO) has a market capitalisation of $927.89M on NasdaqCM.

What is the P/E ratio of JBIO?

JBIO trades at a trailing price-to-earnings (P/E) ratio of -13.64. The industry average P/E is 25.45. Its price-to-book (P/B) ratio is 2.45.

What is the return on equity (ROE) of JBIO?

JBIO has a return on equity (ROE) of -38.32%. Its return on capital employed (ROCE) is -34.07%.

Is JBIO a good stock to buy?

This page provides a data-driven analysis of Jade Biosciences, Inc. (JBIO), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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