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Insmed Incorporated INSM R3KPHARMA

Healthcare · Biotechnology · United States
https://www.insmed.com
Company Profile ↓
$124.89
+1.64% 1Y
Mkt Cap$27.27B
P/E-30.31
P/B34.58
52W High$211.41
52W Low$91.88
Book Value$3.47
EPS (TTM)$-4.12

Company Overview

Insmed Incorporated develops and commercializes therapies for patients with serious and rare diseases in the United States, Europe, Japan, and internationally. The company offers ARIKAYCE for the treatment of refractory nontuberculous mycobacterial lung infections, as well as is in phase 3 clinical trial for the treatment of mycobacterium avium complex lung disease as part of a combination antibacterial drug regimen for adult patients. It also develops brensocatib, an oral reversible inhibitor of dipeptidyl peptidase 1(DPP1) that is in phase 3 clinical trial for the treatment of bronchiectasis; and in phase 2 clinical trial for the treatment of chronic rhinosinusitis without nasal polyps and hidradenitis suppurativa. In addition, the company is developing treprostinil palmitil inhalation powder, an inhaled formulation of a treprostinil prodrug treprostinil palmitil, which is in phase 3 clinical trial for the treatment of pulmonary hypertension associated with interstitial lung disease; and phase 2 clinical trial for the treatment of pulmonary arterial hypertension. Further, it develops INS1201, a microdystrophin adeno-associated virus gene replacement therapy which is in phase 1 clinical trial for the treatment of Duchenne muscular dystrophy, as well as it is also developing pre-clinical research programs for gene therapy, AI-driven protein engineering, protein manufacturing, RNA end-joining, and synthetic rescue. In addition, it provides INS1148, monoclonal antibody targeting stem cell factor called SCF248 that is in phase-2 clinical trial for the treatment of interstitial lung disease, and asthma; and INS1202, an intrathecally delivered gene therapy which is in phase 1 of clinical trial for the treatment of amyotrophic lateral sclerosis. The company was founded in 1988 and is headquartered in Bridgewater, New Jersey.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 31.2% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $606.42M (+66.7% YoY); net profit $-1.28B.
  • Trailing 12 Months Year-on-year growth — revenue +296.1%.
  • 5-Year Trend Long-term compounding — revenue CAGR 31.2%.

Growth & Price Performance

Compounded Sales Growth

5 Years:31.16%
1 Year:296.10%

Stock Price Performance

1 Year:+1.64%
6 Months:-12.74%
3 Months:+32.62%
1 Month:-4.74%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Mixed
52-Week Range 28% of range
$91.88 $211.41
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMABelow
  • RSI (14)55.25 · Neutral
Price Performance
1M-4.74%
3M+32.62%
6M-12.74%
1Y+1.64%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 31.2% over 5 years.

CONS

  • Trading 40.9% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-30.31
Industry PE
24.83
Forward P/E
162.92
PEG Ratio
1.09
Book Value
$3.47
Price to Book
34.58
P/S
23.04
EV/EBITDA
-33.53
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
31.16%
Profit 5Y
-
Revenue (YoY)
296.10%
Earnings (YoY)
-

Profitability & Returns

ROCE
-69.43%
ROE
-87.22%
ROA
-22.17%
Profit Margin
-76.94%
Op Margin
-23.81%
Gross Margin
83.45%
EPS (Latest Qtr)
$-0.06
EPS (TTM)
$-4.12

Balance Sheet & Liquidity

Debt/Equity
0.98
Quick Ratio
3.13
Current Ratio
3.72
Debt
$739.72M
Total Assets
$2.10B
Current Assets
$1.61B
Working Capital
$1.25B

Ownership

Promoter Holding
0.51%
Chg in Prom Hold
-0.01%
FII / Inst Holding
105.01%
Chg in FII Hold
0.16%

Financial Snapshot

Enterprise Value
$27.27B
Total Revenue (TTM)
$1.14B
EBITDA
$-794.96M
Free Cash Flow
$-571.82M
Operating Cash Flow
$-778.92M
Shares Outstanding
218.38M
Gross Margin
83.45%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 INSM Insmed Incorporated R3KPHARMA 124.89 -30.31 $27.27B 0.00% -69.43% -87.22% 31.16% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue --------00000009.84M21.90M29.97M38.88M45.71M36.86M42.49M43.64M40.21M45.37M46.76M53.11M65.22M67.73M65.21M77.23M79.07M75.50M90.34M93.42M92.82M107.42M142.34M305.96M425.49M
Gross Profit ------------0007.41M17.75M25.05M32.45M37.00M28.42M32.55M33.02M-----------------
Operating Income -26.71M-27.95M-30.25M-32.59M-33.07M-36.13M-37.15M-67.05M-35.97M-43.52M-44.08M-65.35M-62.75M-72.88M-83.98M-87.72M-69.51M-62.17M-56.49M-47.08M-60.36M-54.11M-56.22M-83.83M-88.57M-103.62M-89.83M-88.32M-127.70M-148.16M-235.53M-147.67M-145.50M-288.90M-213.43M-248.14M-312.88M-366.00M-153.32M-1.55M
Net Income -27.37M-28.61M-30.96M-31.25M-33.53M-36.58M-37.76M-68.40M-37.41M-44.67M-45.18M-65.38M-68.52M-76.44M-87.74M-91.57M-74.15M-66.51M-60.68M-52.99M-66.36M-61.85M-63.66M-91.64M-117.32M-112.71M-94.62M-95.64M-131.15M-159.76M-244.81M-158.93M-157.09M-300.61M-220.52M-256.58M-321.69M-370.02M-163.56M-13.24M
Diluted EPS ----------------------0.64-0.63-0.89-1.07-0.96-0.80-0.80-1.09-1.17-1.78-1.11-1.06-1.94-1.27-1.42-1.70-1.75-0.76-0.06
R&D Expense 17.16M18.25M19.22M-20.55M23.87M23.43M-22.25M26.87M26.68M-30.10M35.72M39.54M-31.20M33.54M34.34M-36.18M35.75M41.41M61.39M64.66M70.35M84.36M88.53M99.87M127.86M196.97M109.15M121.08M146.75M150.81M152.58M177.19M186.41M209.49M210.03M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 10.37M6.92M4.42M011.50M-0009.84M136.47M164.41M188.46M245.36M305.21M363.71M606.42M
Gross Profit --------07.41M112.25M------
Operating Income -8.67M-8.09M-61.72M-42.44M-55.02M-87.36M-117.49M-173.40M-188.92M-307.34M-235.25M-265.23M-375.09M-457.32M-709.63M-878.25M-1.25B
Net Income 118.35M-6.43M-59.66M-41.37M-56.07M-79.16M-118.18M-176.27M-192.65M-324.28M-254.34M-294.09M-434.65M-481.53M-749.57M-913.77M-1.28B
Diluted EPS 9.30-0.49-2.95--------3.01-3.01-3.88-3.91-5.34-5.57-6.42
R&D Expense 9.21M4.70M28.62M29.78M44.28M56.29M74.28M122.72M109.75M145.28M131.71M181.16M272.74M397.52M571.01M598.37M771.09M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2008Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --196.26M139.83M153.56M176.50M230.86M356.56M237.96M462.05M604.56M742.30M796.15M1.24B1.66B1.33B2.03B2.26B
Total Equity -2.82M123.91M192.84M134.27M120.88M143.32M186.24M311.70M154.48M361.06M208.27M261.67M275.88M410.47M87.95M-331.92M285.38M738.98M
Cash & Equivalents --10.74M14.85M90.78M113.89M159.23M282.88M162.59M381.17M495.07M487.43M532.76M716.78M1.07B482.37M555.03M510.44M
Long Term Debt ---016.22M16.34M24.86M22.03M54.79M55.57M316.56M335.94M356.32M566.59M1.13B1.16B1.10B540.96M
Total Liabilities --3.42M5.57M32.68M33.17M44.63M44.86M83.47M100.99M396.29M480.62M520.27M833.04M1.57B1.66B1.74B1.53B
Current Liabilities --3.34M4.48M15.75M16.46M19.63M22.26M27.99M44.66M79.73M85.24M118.81M135.17M190.24M225.63M297.53M468.87M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -11.01M-7.72M-30.20M-31.01M---100.70M-146.71M-159.62M-257.98M-250.65M-219.35M-363.30M-400.44M-536.25M-683.88M-935.01M
Investing Cash Flow 18.73M5.96M34.36M61.52M---3.45M-4.20M-3.00M-14.81M-42.27M-6.82M-64.28M-34.58M-223.60M-583.17M-64.58M
Financing Cash Flow 2.88M-233.00K-50.00K45.42M--227.80M30.67M381.09M386.74M285.28M271.00M612.55M793.27M168.44M1.34B954.07M
Capital Expenditure -0-0-979.00K-290.00K-826.00K-5.35M-3.45M-4.20M-3.00M-13.09M-42.27M-6.24M-7.29M-9.88M-13.29M-21.92M-32.56M
Free Cash Flow -11.01M-7.72M-31.18M-31.30M---104.15M-150.91M-162.62M-271.07M-292.92M-225.59M-370.59M-410.32M-549.53M-705.80M-967.58M

Ratios (Annual)

Figures in %.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ---------75.4%82.3%------
Operating Margin % -83.6%-116.9%-1,397.3%--478.4%-----3,124.9%-172.4%-161.3%-199.0%-186.4%-232.5%-241.5%-205.6%
Net Margin % 1,140.9%-93.0%-1,350.8%--487.6%-----3,297.2%-186.4%-178.9%-230.6%-196.3%-245.6%-251.2%-210.5%
ROE % 95.5%-3.3%-44.4%-34.2%-39.1%-42.5%-37.9%-114.1%-53.4%-155.7%-97.2%-106.6%-105.9%-547.5%225.8%-320.2%-172.8%
ROCE % --4.2%-45.6%-30.8%-34.4%-41.4%-35.1%-82.6%-45.3%-58.6%-35.8%-39.2%-33.8%-31.2%-64.3%-50.8%-69.4%

Shareholding Pattern

Insiders
0.51%
Institutions
105.01%
Public Float
105.54%

Top Institutional Holders

#Holder% HeldSharesValue
1 FMR, LLC 7.39% 16.14M $1.94B
2 Blackrock Inc. 7.24% 15.81M $1.90B
3 JPMORGAN CHASE & CO 4.78% 10.43M $1.25B
4 Vanguard Portfolio Management LLC 4.77% 10.41M $1.25B
5 Vanguard Capital Management LLC 4.48% 9.79M $1.17B
6 Baker Bros. Advisors, LP 4.03% 8.80M $1.06B
7 Capital International Investors 3.77% 8.24M $988.57M
8 Darwin Global Management, Ltd. 2.94% 6.43M $771.74M
9 Ameriprise Financial, Inc. 2.83% 6.18M $741.55M
10 Orbis Allan Gray Ltd 2.78% 6.08M $729.18M

Analyst View

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Latest News

Recent headlines for INSM

Google News ue, 08 Sep 2026

Insmed: A Strong Launch And A Much Bigger Peak Sales Opportunity (NASDAQ:INSM) - Seeking Alpha

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Google News Sat, 05 Sep 2026

Insmed Stock Price Forecast. Should You Buy INSM? - StockInvest.us

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Google News Fri, 04 Sep 2026

128 new employees receive stock awards from Insmed - Stock Titan

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Google News Mon, 07 Sep 2026

Here's How Much $100 Invested In Insmed 5 Years Ago Would Be Worth Today - Benzinga

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Google News Wed, 02 Sep 2026

Do You Believe in Insmed’s INSM) Long-Term Potential Despite Short-Term Challenges? - finance.yahoo.com

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Google News hu, 03 Sep 2026

Insmed director Sharoky sells $637,650 of Insmed stock - Investing.com

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INSM — Frequently Asked Questions

What is the current share price of Insmed Incorporated (INSM)?

As of 2026-09-19 21:16 PDT, Insmed Incorporated (INSM) trades at $124.89 on NasdaqGS. Its 52-week range is $91.88 to $211.41.

What is the market capitalisation of INSM?

Insmed Incorporated (INSM) has a market capitalisation of $27.27B on NasdaqGS.

What is the P/E ratio of INSM?

INSM trades at a trailing price-to-earnings (P/E) ratio of -30.31. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 34.58.

What is the return on equity (ROE) of INSM?

INSM has a return on equity (ROE) of -87.22%. Its return on capital employed (ROCE) is -69.43%.

Is INSM a good stock to buy?

This page provides a data-driven analysis of Insmed Incorporated (INSM), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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