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Heron Therapeutics, Inc. HRTX R2K

Healthcare · Biotechnology · United States
https://www.herontx.com
Company Profile ↓
$0.43
-79.72% 1Y
Mkt Cap$81.39M
P/E-2.39
P/B9.30
52W High$2.12
52W Low$0.38
Book Value$0.04
EPS (TTM)$-0.18

Company Overview

Heron Therapeutics, Inc., a commercial-stage biotechnology company, engages in developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic levels of a range of short-acting pharmacological agents over a period from days to weeks with a single administration. It offers SUSTOL (granisetron), an extended-release injection for the prevention of acute and delayed nausea and vomiting associated with moderately emetogenic chemotherapy, or anthracycline and cyclophosphamide combination chemotherapy regimens; and CINVANTI, an intravenous formulation of aprepitant, a substance P/neurokinin-1 receptor antagonist for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cancer chemotherapy, as well as nausea and vomiting associated with moderately emetogenic cancer chemotherapy. The company is also developing ZYNRELEF, a dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low dose of the nonsteroidal anti-inflammatory drug meloxicam; and APONVIE, an intravenous formulation of a substance P/neurokinin-1 receptor antagonist indicated for the prevention of postoperative nausea and vomiting in adults. Heron Therapeutics, Inc. was formerly known as A.P. Pharma, Inc. and changed its name to Heron Therapeutics, Inc. in January 2014. The company was founded in 1983 and is headquartered in Cary, North Carolina.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 70.4% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $154.90M (+7.4% YoY); net profit $-20.20M.
  • Trailing 12 Months Year-on-year growth — revenue -10.8%.
  • 5-Year Trend Long-term compounding — revenue CAGR 70.4%.

Growth & Price Performance

Compounded Sales Growth

5 Years:70.40%
1 Year:-10.80%

Stock Price Performance

1 Year:-79.72%
6 Months:-69.07%
3 Months:-52.76%
1 Month:+4.85%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 3% of range
$0.38 $2.12
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)38.99 · Neutral
Price Performance
1M+4.85%
3M-52.76%
6M-69.07%
1Y-79.72%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 70.4% over 5 years.

CONS

  • Trading 79.7% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-2.39
Industry PE
25.41
Forward P/E
-
PEG Ratio
-
Book Value
$0.04
Price to Book
9.30
P/S
0.50
EV/EBITDA
-21.27
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
70.40%
Profit 5Y
-
Revenue (YoY)
-10.80%
Earnings (YoY)
-

Profitability & Returns

ROCE
-1.59%
ROE
-140.90%
ROA
-2.71%
Profit Margin
-20.53%
Op Margin
-13.73%
Gross Margin
62.80%
EPS (Latest Qtr)
$-0.04
EPS (TTM)
$-0.18

Balance Sheet & Liquidity

Debt/Equity
15.50
Quick Ratio
1.42
Current Ratio
2.53
Debt
$141.63M
Total Assets
$246.22M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
0.90%
Chg in Prom Hold
0.00%
FII / Inst Holding
83.29%
Chg in FII Hold
-0.04%

Financial Snapshot

Enterprise Value
$81.39M
Total Revenue (TTM)
$150.71M
EBITDA
$-8.16M
Free Cash Flow
$-18.44M
Operating Cash Flow
$-20.26M
Shares Outstanding
189.28M
Gross Margin
62.80%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 HRTX Heron Therapeutics, Inc. R2K 0.43 -2.39 $81.39M 0.00% -1.59% -140.90% 70.40% -
2 LLY Eli Lilly and Company SPX 1,152.54 41.02 $1.03T 0.61% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 253.85 29.45 $611.07B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.78 119.40 $432.48B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 425.19 32.02 $386.13B 2.27% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 120.78 34.02 $298.31B 2.86% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 164.50 24.81 $255.12B 1.77% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 534.07 29.33 $198.47B 0.40% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 355.25 24.69 $191.73B 2.84% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Dec 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Revenue --------3.63M8.51M8.57M10.05M11.57M17.28M19.79M28.84M31.60M36.66M42.62M35.08M25.40M22.67M19.96M20.61M20.02M22.44M23.23M23.46M27.63M26.56M29.61M31.76M31.43M34.67M36.02M32.81M38.90M37.20M38.21M34.71M
Gross Profit -------1.24M2.45M7.50M7.52M8.71M8.43M12.05M12.21M17.27M16.64M23.07M25.43M19.21M14.78M13.66M12.79M11.21M-----11.84M12.76M11.60M13.23M26.23M25.51M23.35M30.45M27.34M26.30M24.07M
Operating Income -20.36M-23.01M-22.49M--33.31M-43.07M-47.73M--49.30M-42.05M-41.31M--51.99M-38.85M-41.78M-51.31M-64.70M-51.78M-34.85M-59.36M-52.73M-55.75M-58.38M-61.30M-52.11M-60.47M-51.71M-62.92M-49.50M-41.88M-33.06M-42.40M-24.93M-4.80M-6.45M-4.46M3.15M-1.64M-4.09M-4.76M
Net Income -20.57M-23.11M-22.67M-31.24M-33.45M-43.23M-48.51M-47.96M-50.33M-42.80M-41.87M-62.49M-52.27M-38.67M-38.35M-49.56M-63.01M-50.22M-33.59M-57.92M-51.58M-55.19M-58.23M-62.28M-52.61M-61.02M-52.41M-63.89M-56.36M-41.91M-32.77M-42.06M-25.01M-3.16M-9.23M-4.85M2.63M-2.38M-17.50M-8.11M
Diluted EPS --------------------------0.62-0.51-0.63-0.55-0.38-0.27-0.35-0.17-0.02-0.06-0.030.01-0.02-0.10-0.04
R&D Expense 14.50M16.18M14.24M16.26M16.09M27.29M30.24M29.50M33.38M28.60M28.84M47.76M39.56M30.16M30.42M39.89M42.97M41.42M34.71M48.28M36.89M44.00M49.18M44.45M38.12M35.23M28.59M42.07M28.83M25.55M8.84M13.21M9.29M4.61M4.43M4.46M2.28M2.93M3.47M2.38M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -------1.28M30.77M77.47M145.97M88.64M86.35M107.67M127.04M144.28M154.90M
Gross Profit -------------52.80M61.94M105.64M113.56M
Operating Income -10.24M-9.93M-11.06M-23.83M-54.46M-74.56M-96.92M-170.91M-194.56M-183.94M-210.69M-228.16M-217.83M-174.66M-110.61M-11.53M-2.54M
Net Income -10.03M-7.35M-11.81M-23.35M-55.28M-76.37M-97.59M-173.14M-197.48M-178.84M-204.75M-227.28M-220.68M-182.02M-110.56M-13.58M-20.20M
Diluted EPS -------------2.24-1.67-0.80-0.09-0.12
R&D Expense 7.80M7.26M8.21M15.17M32.52M54.83M61.18M103.12M138.58M140.03M167.38M174.53M130.82M82.70M39.13M16.68M12.43M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2008Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --2.91M19.45M55.97M75.94M76.68M137.84M67.48M234.31M462.18M512.78M353.56M305.71M250.95M222.51M233.15M255.88M
Total Equity -6.80M1.32M15.75M51.82M68.94M63.06M118.11M-21.25M131.14M370.16M403.83M236.49M77.57M13.57M-33.97M-33.65M14.33M
Cash & Equivalents 9.97M7.59M2.11M17.97M53.51M72.29M72.67M75.18M13.41M144.58M31.84M71.90M105.14M90.54M15.36M28.68M25.80M28.65M
Total Liabilities --1.59M3.69M---19.73M88.73M103.17M92.02M108.95M117.06M228.14M237.38M256.48M266.80M241.54M
Current Liabilities --1.56M3.69M4.15M6.99M13.62M19.73M38.73M103.17M92.02M96.70M102.50M71.06M82.36M79.69M91.46M96.10M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -11.00M-5.48M-7.72M-17.01M-40.76M-60.28M-78.53M-134.10M-170.30M-191.81M-124.58M-184.82M-203.35M-146.91M-58.79M-22.53M-27.59M
Investing Cash Flow 612.00K-78.00K-513.00K-972.00K-1.69M-1.44M-56.96M14.88M7.74M-278.55M-21.78M208.96M32.73M-3.32M18.00M18.71M16.01M
Financing Cash Flow 8.01M77.00K24.10M53.51M61.23M62.11M137.99M57.45M293.73M357.61M186.43M9.11M156.03M75.06M54.11M940.00K14.43M
Capital Expenditure -2.00K-78.00K-513.00K-972.00K-1.69M-1.44M-1.09M-3.13M-2.55M-9.17M-7.15M-6.81M-3.02M-1.82M-1.54M-1.71M-317.00K
Free Cash Flow -11.00M-5.56M-8.23M-17.98M-42.45M-61.72M-79.61M-137.23M-172.85M-200.98M-131.73M-191.63M-206.38M-148.74M-60.33M-24.23M-27.91M

Ratios (Annual)

Figures in %.

Metric Dec 2009Dec 2010Dec 2011Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -------------49.0%48.8%73.2%73.3%
Operating Margin % --------13,363.2%-632.4%-237.4%-144.3%-257.4%-252.3%-162.2%-87.1%-8.0%-1.6%
Net Margin % --------13,537.4%-641.9%-230.8%-140.3%-256.4%-255.6%-169.1%-87.0%-9.4%-13.0%
ROE % -147.6%-558.2%-75.0%-45.1%-80.2%-121.1%-82.6%814.8%-150.6%-48.3%-50.7%-96.1%-284.5%-1,341.2%325.4%40.4%-140.9%
ROCE % --735.3%-70.2%-46.0%-79.0%-118.2%-82.1%-594.5%-148.4%-49.7%-50.6%-90.9%-92.8%-103.6%-77.5%-8.1%-1.6%

Shareholding Pattern

Insiders
0.90%
Institutions
83.29%
Public Float
84.04%

Top Institutional Holders

#Holder% HeldSharesValue
1 Rubric Capital Management LP 15.87% 30.05M $12.66M
2 Clearline Capital, LP 6.46% 12.24M $5.16M
3 Blackrock Inc. 5.34% 10.11M $4.26M
4 Orbimed Advisors LLC. 5.19% 9.82M $4.14M
5 Velan Capital Investment Management LP 4.62% 8.75M $3.69M
6 Vanguard Capital Management LLC 4.13% 7.81M $3.29M
7 Millennium Management Llc 4.03% 7.63M $3.22M
8 Tejara Capital Ltd 3.35% 6.34M $2.67M
9 Tang Capital Management, LLC 3.30% 6.25M $2.63M
10 Palisade Capital Management, L.P. 3.24% 6.14M $2.59M

Analyst View

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Latest News

Recent headlines for HRTX

Google News ue, 30 Jun 2026

Is Heron Therapeutics, Inc. (HRTX) Stock a Recovery Opportunity After Cinvanti Patent Court Ruling? - Yahoo Finance

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Google News Sun, 12 Jul 2026

Heron Therapeutics (HRTX) Stock Sees Fair Value Cut After Cinvanti Patent Decision - Yahoo Finance

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Google News Sun, 12 Jul 2026

Heron Therapeutics, Inc. (NASDAQ:HRTX) Receives Consensus Rating of "Hold" from Brokerages - MarketBeat

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Nasdaq warns Heron Therapeutics (NASDAQ: HRTX) on sub-$1.00 bid price - Stock Titan

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HRTX — Frequently Asked Questions

What is the current share price of Heron Therapeutics, Inc. (HRTX)?

As of 2026-07-14 21:23 PDT, Heron Therapeutics, Inc. (HRTX) trades at $0.43 on NasdaqCM. Its 52-week range is $0.38 to $2.12.

What is the market capitalisation of HRTX?

Heron Therapeutics, Inc. (HRTX) has a market capitalisation of $81.39M on NasdaqCM.

What is the P/E ratio of HRTX?

HRTX trades at a trailing price-to-earnings (P/E) ratio of -2.39. The industry average P/E is 25.41. Its price-to-book (P/B) ratio is 9.30.

What is the return on equity (ROE) of HRTX?

HRTX has a return on equity (ROE) of -140.90%. Its return on capital employed (ROCE) is -1.59%.

Is HRTX a good stock to buy?

This page provides a data-driven analysis of Heron Therapeutics, Inc. (HRTX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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