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$2.51
-90.68% 1Y
Mkt Cap$4.61M
P/E-0.15
P/B0.41
52W High$36.12
52W Low$1.61
Book Value$4.59
EPS (TTM)$-16.62

Company Overview

HCW Biologics Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing novel immunotherapies for chronic, low-grade inflammation, and diseases in the United States. Its lead products include HCW11-018b, a novel, tetra-valent T-Cell engager; HCW11-040, a multifunctional fusion molecule that is a combination of cytokines and pembrolizumab; and HCW9302, injectable and interleukin 2 (IL-2) fusion protein complex, which is in clinical trial in patients with alopecia areata diseases. The company also develops HCW9201, a fusion protein designed as a reagent to use in the production of natural killer (NK) cell-based therapies; HCW9206, a fusion protein designed as a reagent to use in the production of CAR-therapies for the treatment of infectious diseases; and HCW11-006, a multi-functional immune cell stimulator. It has a license agreement with Wugen Inc. to develop cell therapy-based treatments; and a license, research and co-development agreement with WY Biotech Co., Ltd. for its preclinical molecule. HCW Biologics Inc. was incorporated in 2018 and is headquartered in Miramar, Florida.

Recent Developments

  • Dec 2025 Revenue of $54.23K (-97.9% YoY); net profit $-7.96M.
  • Trailing 12 Months Year-on-year growth — revenue +1969.7%.
  • 5-Year Trend Long-term compounding — revenue CAGR -57.9%.

Growth & Price Performance

Compounded Sales Growth

5 Years:-57.90%
1 Year:1,969.70%

Stock Price Performance

1 Year:-90.68%
6 Months:-29.45%
3 Months:-71.15%
1 Month:-26.39%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 3% of range
$1.61 $36.12
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)39.96 · Neutral
Price Performance
1M-26.39%
3M-71.15%
6M-29.45%
1Y-90.68%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Revenue declined at -57.9% CAGR over 5 years.
  • Trading 93.0% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-0.15
Industry PE
24.83
Forward P/E
-4.56
PEG Ratio
-
Book Value
$4.59
Price to Book
0.41
P/S
0.51
EV/EBITDA
-1.68
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-57.90%
Profit 5Y
-
Revenue (YoY)
1,969.70%
Earnings (YoY)
-

Profitability & Returns

ROCE
-
ROE
-
ROA
-13.88%
Profit Margin
-83.05%
Op Margin
-
Gross Margin
95.91%
EPS (Latest Qtr)
$2.22
EPS (TTM)
$-16.62

Balance Sheet & Liquidity

Debt/Equity
0.88
Quick Ratio
0.04
Current Ratio
0.06
Debt
$6.56M
Total Assets
$27.34M
Current Assets
$2.28M
Working Capital
$-18.78M

Ownership

Promoter Holding
9.72%
Chg in Prom Hold
-0.97%
FII / Inst Holding
9.03%
Chg in FII Hold
0.81%

Financial Snapshot

Enterprise Value
$4.61M
Total Revenue (TTM)
$6.72M
EBITDA
$-5.58M
Free Cash Flow
$-11.66M
Operating Cash Flow
$-12.14M
Shares Outstanding
1.84M
Gross Margin
95.91%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 HCWB HCW Biologics Inc. PHARMA 2.51 -0.15 $4.61M 0.00% - - -57.90% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue ----------------5.07K6.55K15.61K27.01K6.54M
Cost of Revenue ----------------4.05K5.24K12.48K21.61K11.07K
Gross Profit ---0001.79M166.80K361.81K12.53K120.41K174.78K614.75K180.41K85.28K-1.01K1.31K3.12K5.40K6.53M
Operating Expenses ----------------1.69M3.36M3.28M2.95M3.28M
Operating Income --2.78M-2.71M-3.41M-2.75M-4.09M-1.88M-3.51M-4.02M-5.36M-4.51M-5.08M-7.49M-15.14M-3.68M--1.69M-3.36M-3.28M-2.95M3.25M
EBITDA -----------------1.25M-1.30M-4.24M1.10M4.07M
Interest Expense ----------------528.88K330.96K142.57K226.54K123.69K
Pretax Income -----------------2.20M-1.93M-4.55M719.23K3.80M
Tax Provision ----------------0---330.19K
Net Income -2.38M-2.78M-2.71M-2.84M-2.75M-4.09M-2.06M-3.51M-3.91M-5.07M-4.30M-4.94M-7.47M-15.28M-3.90M--2.20M-1.93M-4.55M719.23K3.47M
Diluted EPS -----0.66-0.14-0.06-0.10-0.11-0.14-0.12-0.14-0.20-16.16-4.13--11.82-5.39-12.12-6.122.22
R&D Expense -2.07M2.10M2.33M1.67M2.69M1.79M1.97M2.65M2.26M1.62M1.67M2.12M2.03M1.19M-1.48M1.23M1.40M-1.26M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 4.10M06.72M2.84M2.57M54.23K
Gross Profit -02.59M560.36K959.40K10.85K
Operating Income -5.82M-13.37M-15.08M-25.72M-29.46M-13.16M
Net Income -5.80M-12.86M-14.90M-24.99M-30.02M-7.96M
Diluted EPS --0.69-0.42-0.70-30.96-10.63
R&D Expense 7.26M8.17M9.34M7.68M6.39M5.44M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -15.40M-46.81M28.51M30.24M24.52M
Current Assets ---34.07M6.40M5.70M2.28M
Cash & Equivalents 7.36M8.46M-22.33M3.60M4.67M1.95M
Inventory -------
Receivables ---417.69K1.54M582.20K32.17K
Total Liabilities ---9.38M15.05M37.01M21.76M
Current Liabilities -1.00M-2.96M8.75M29.63M21.06M
Long Term Debt ---6.41M6.30M7.38M-
Total Debt ---6.41M6.30M13.69M6.81M
Total Equity -9.68M-16.72M-37.43M13.46M-6.77M2.76M
Shares Outstanding ---149.49K150.10K185.59K546.63K

Cash Flows (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -10.43M-10.98M-10.39M-22.51M-14.23M-13.39M
Investing Cash Flow -186.68K-35.02M14.71M3.80M-261.62K0
Financing Cash Flow 11.72M49.27M6.27M-14.53K15.57M10.67M
Capital Expenditure -186.68K-47.26K-10.28M-6.20M-261.62K-0
Free Cash Flow -10.62M-11.02M-20.66M-28.72M-14.49M-13.39M

Ratios (Annual)

Figures in %.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % --38.5%19.7%37.4%20.0%
Operating Margin % -142.1%--224.3%-905.0%-1,147.6%-24,270.7%
Net Margin % -141.5%--221.7%-879.5%-1,169.7%-14,677.1%
ROE % 34.7%--39.8%-185.7%443.5%-287.9%
ROCE % -40.5%--34.4%-130.1%-4,847.3%-380.7%

Shareholding Pattern

Insiders
9.72%
Institutions
9.03%
Public Float
10.00%

Top Institutional Holders

#Holder% HeldSharesValue
1 Jane Street Group, LLC 2.84% 52.14K $97.50K
2 Citadel Advisors Llc 1.09% 19.94K $37.29K
3 HRT Financial LP 0.74% 13.58K $25.40K
4 Vanguard Fiduciary Trust Co 0.35% 6.51K $12.17K
5 Tower Research Capital LLC (TRC) 0.22% 4.12K $7.70K
6 Connective Capital Management LLC 0.18% 3.34K $6.24K
7 Vanguard Capital Management LLC 0.11% 2.00K $3.75K
8 Golden State Wealth Management, Llc 0.09% 1.67K $3.12K
9 Barclays Plc 0.01% 191 $357
10 Caitong International Asset Management Co., Ltd - 11 $20

Analyst View

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Latest News

Recent headlines for HCWB

Google News ue, 08 Sep 2026

$HCWB stock is down 12% today. Here's what we see in our data. - Quiver Quantitative

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Google News ue, 08 Sep 2026

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Google News ue, 08 Sep 2026

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Google News Sat, 05 Sep 2026

Hcw Biologics Stock Price Forecast. Should You Buy HCWB? - StockInvest.us

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HCWB — Frequently Asked Questions

What is the current share price of HCW Biologics Inc. (HCWB)?

As of 2026-09-19 21:16 PDT, HCW Biologics Inc. (HCWB) trades at $2.51 on NasdaqCM. Its 52-week range is $1.61 to $36.12.

What is the market capitalisation of HCWB?

HCW Biologics Inc. (HCWB) has a market capitalisation of $4.61M on NasdaqCM.

What is the P/E ratio of HCWB?

HCWB trades at a trailing price-to-earnings (P/E) ratio of -0.15. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 0.41.

Is HCWB a good stock to buy?

This page provides a data-driven analysis of HCW Biologics Inc. (HCWB), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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