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$3.54
-98.57% 1Y
Mkt Cap$2.90M
P/E0.10
P/B0.12
52W High$924.00
52W Low$3.42
Book Value$29.23
EPS (TTM)$34.43

Company Overview

Genprex, Inc., a clinical-stage gene therapy company, focuses on developing therapies for patients with cancer and diabetes. The company's technologies are designed to administer disease-fighting genes to provide new therapies for patient populations with cancer and diabetes. Its oncology program utilizes its systemic, non-viral Oncoprex Delivery System, which encapsulates the gene-expressing plasmids using lipid-based nanoparticles in a lipoplex form. The company's lead product candidate, Reqorsa Gene Therapy (quaratusugene ozeplasmid), is being evaluated in three clinical trials as a treatment for NSCLC and SCLC. It also develops REQORSA Gene Therapy in Mesothelioma, Ras Inhibitor Resistant NSCLC, other tumor suppressor genes, and Glioblastoma, which is in preclinical studies. Its three-lung cancer clinical programs have received a Fast Track Designation from the FDA for the treatment of that patient population, and SCLC program has received an FDA Orphan Drug Designation. The company's diabetes gene therapy comprises of a novel infusion process that uses an AAV vector to deliver Pdx1 and MafA genes directly to the pancreas. In models of Type 1 diabetes, its GPX-002 transforms alpha cells in the pancreas into functional beta-like cells, which produce insulin but distinct enough from beta cells to evade the body's immune system; and GPX-002 for Type 2 diabetes, where autoimmunity is not at play, is believed to rejuvenate and replenish exhausted beta cells. It has research agreement with The University of Michigan Rogel Cancer Center and Lung Cancer Study Collaboration with ALK Positive; New York University; UTHealth Houston; and University of Pittsburgh. The company also has a sponsored research agreement with The University of Texas MD Anderson Cancer Center to study biomarkers that for the prediction of patient response to Reqorsa Gene Therapy. Genprex, Inc. was incorporated in 2009 and is based in Austin, Texas.

Why Investors Should Care

Reasonable Valuation

Trades at a P/E of 0.1, below the sector median of 24.8.

Growth & Price Performance

Stock Price Performance

1 Year:-98.57%
6 Months:-91.87%
3 Months:-76.02%
1 Month:-17.10%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 0% of range
$3.42 $924.00
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • RSI (14)28.77 · Oversold
Price Performance
1M-17.10%
3M-76.02%
6M-91.87%
1Y-98.57%
Valuation vs Sector

P/E of 0.10 is below the sector median of 24.83 — relatively cheaper than peers.

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

No notable strengths flagged.

CONS

  • Trading 99.6% below its 52-week high.
  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
0.10
Industry PE
24.83
Forward P/E
-1.62
PEG Ratio
-
Book Value
$29.23
Price to Book
0.12
P/S
-
EV/EBITDA
-
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-
ROE
-
ROA
-94.46%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-14.08
EPS (TTM)
$34.43

Balance Sheet & Liquidity

Debt/Equity
-
Quick Ratio
6.47
Current Ratio
6.76
Debt
$0
Total Assets
$20.31M
Current Assets
$8.36M
Working Capital
$6.18M

Ownership

Promoter Holding
0.21%
Chg in Prom Hold
-0.13%
FII / Inst Holding
1.73%
Chg in FII Hold
-0.01%

Financial Snapshot

Enterprise Value
$2.90M
Total Revenue (TTM)
$0
EBITDA
-
Free Cash Flow
$-10.58M
Operating Cash Flow
$-15.56M
Shares Outstanding
819.71K
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 GNPX Genprex, Inc. PHARMA 3.54 0.10 $2.90M 0.00% - - - -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Sep 2016Mar 2017Jun 2017Sep 2017Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue 00000000---00000000-------00000
Cost of Revenue -------------------------------
Gross Profit -------------------------------
Operating Expenses --------------------------3.97M4.68M3.35M3.52M4.49M
Operating Income -719.86K-751.30K-1.18M-715.12K-686.63K-6.04M-2.20M-2.17M-3.70M-2.38M-5.58M-4.38M-2.78M-5.31M-3.99M-3.44M-5.31M-5.77M-6.17M-9.26M-8.04M-7.79M-6.00M-6.52M-4.32M--3.97M-4.68M-3.35M-3.52M-4.49M
EBITDA ---------------------------3.97M-4.68M-3.34M-3.51M-4.49M
Interest Expense ----------------------------455.55K284.39K-
Pretax Income ---------------------------3.96M-4.67M-3.80M-3.79M-4.46M
Tax Provision -------------------------------
Net Income -719.86K-751.30K-1.18M-715.10K-694.00K-6.06M-2.19M-2.16M-3.70M-2.38M-5.57M-4.37M-2.77M-5.31M-3.99M-3.44M-5.31M-5.76M-6.14M-9.20M-7.98M-7.75M-5.97M-6.50M-4.32M--3.96M-4.67M-3.80M-3.79M-4.46M
Diluted EPS ---------------------------285.56-187.00-110.00--14.08
R&D Expense 89.90K68.36K104.98K55.52K51.62K112.97K489.69K508.04K502.04K467.34K1.48M2.16M1.35M2.04M1.53M1.43M2.04M2.93M3.16M5.31M3.98M4.62M3.27M1.67M2.76M-2.54M2.50M2.19M-2.75M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 000-00000-
Operating Income -4.13M-3.31M-12.36M-10.68M-17.96M-20.67M-23.83M-31.06M-21.17M-15.52M
Net Income -4.13M-3.31M-12.37M-10.65M-17.94M-20.66M-23.74M-30.86M-21.11M-16.23M
R&D Expense 354.88K289.93K971.43K1.97M7.30M8.97M11.51M17.62M10.54M9.43M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Mar 2022Jun 2022Sep 2022Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -1.91M1.26M9.27M3.53M31.37M-39.41M34.57M29.95M25.09M10.67M4.12M10.16M
Current Assets ----------21.47M7.53M2.08M8.36M
Cash & Equivalents 234.22K1.60M161.25K-------20.95M6.74M1.60M7.83M
Inventory --------------
Receivables ------0---34.85K0--
Total Liabilities -------2.38M2.15M2.46M2.81M3.25M2.50M2.20M
Current Liabilities -285.66K830.96K387.82K510.68K450.72K----2.81M3.25M2.50M2.17M
Long Term Debt --------------
Total Debt --------------
Total Equity 393.74K1.62M428.57K8.88M3.02M30.92M-37.02M32.41M27.49M22.27M7.42M1.62M7.96M
Shares Outstanding ----------1.09K1.35K9.87K149.61K

Cash Flows (Annual)

Figures in USD.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -1.25M-2.17M-6.85M-6.92M-13.94M-14.28M-17.62M-24.74M-17.92M-15.31M
Investing Cash Flow -89.53K-63.42K-103.32K-946.90K-2.34M-83.80K-59.73K-71.21K774.64K0
Financing Cash Flow 2.71M793.97K15.39M1.27M41.59M25.68M6.43K10.59M12.01M21.54M
Capital Expenditure -4.98K-5.89K-22.43K-33.37K-17.56K-31.70K-0---
Free Cash Flow -1.25M-2.18M-6.87M-6.95M-13.95M-14.32M-17.62M---

Ratios (Annual)

Figures in %.

Metric Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ----------
Operating Margin % ----------
Net Margin % ----------
ROE % -254.3%-773.3%-139.3%-352.4%-58.0%--106.6%-416.1%-1,303.0%-203.8%
ROCE % -254.3%-772.9%-139.2%-353.3%-58.1%--107.0%-418.8%-1,306.9%-194.3%

Shareholding Pattern

Insiders
0.21%
Institutions
1.73%
Public Float
1.73%

Top Institutional Holders

#Holder% HeldSharesValue
1 Vanguard Fiduciary Trust Co 0.43% 3.55K $12.25K
2 HRT Financial LP 0.40% 3.28K $11.30K
3 Geode Capital Management, LLC 0.33% 2.74K $9.46K
4 Vanguard Capital Management LLC 0.20% 1.65K $5.70K
5 Cheviot Value Management, LLC 0.12% 1.00K $3.45K
6 Engineers Gate Manager Lp 0.12% 949 $3.27K
7 Mayflower Financial Advisors, LLC 0.11% 909 $3.14K
8 Tower Research Capital LLC (TRC) 0.02% 129 $445
9 UBS Group AG 0.02% 204 $703
10 Harbour Investments, Inc. 0.01% 108 $372

Analyst View

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Latest News

Recent headlines for GNPX

Google News ue, 08 Sep 2026

A biotech will discuss gene therapies for cancer and diabetes - Stock Titan

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Google News Sat, 05 Sep 2026

Genprex Stock Price Forecast. Should You Buy GNPX? - StockInvest.us

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Google News ue, 21 Apr 2026

$GNPX stock is up 8% today. Here's what we see in our data. - Quiver Quantitative

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Google News Mon, 03 Aug 2026

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Google News ue, 18 Aug 2026

Genprex is scaling a diabetes therapy designed to deliver two genes to the pancreas - Stock Titan

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Google News Wed, 15 Jul 2026

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GNPX — Frequently Asked Questions

What is the current share price of Genprex, Inc. (GNPX)?

As of 2026-09-19 21:16 PDT, Genprex, Inc. (GNPX) trades at $3.54 on NasdaqCM. Its 52-week range is $3.42 to $924.00.

What is the market capitalisation of GNPX?

Genprex, Inc. (GNPX) has a market capitalisation of $2.90M on NasdaqCM.

What is the P/E ratio of GNPX?

GNPX trades at a trailing price-to-earnings (P/E) ratio of 0.10. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 0.12.

Is GNPX a good stock to buy?

This page provides a data-driven analysis of Genprex, Inc. (GNPX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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