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Edgewise Therapeutics, Inc. EWTX R2K

Healthcare · Biotechnology · United States
https://edgewisetx.com
Company Profile ↓
$40.83
+193.11% 1Y
Mkt Cap$4.39B
P/E-24.60
P/B8.66
52W High$48.35
52W Low$12.68
Book Value$4.59
EPS (TTM)$-1.66

Company Overview

Edgewise Therapeutics, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders. Its lead product candidate, sevasemten, an orally administered small molecule that is in Phase II clinical trials, designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy. The company develops EDG-7500, a small molecule for the treatment of hypertrophic cardiomyopathy and other severe cardiac disorders that is in Phase I clinical trials; and EDG-15400, a novel small molecule for the treatment of heart failure with preserved ejection fraction. In addition, it develops a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address genetically defined muscle disorders. The company was incorporated in 2017 and is headquartered in Boulder, Colorado.

Growth & Price Performance

Stock Price Performance

1 Year:+193.11%
6 Months:+69.21%
3 Months:+23.13%
1 Month:+17.23%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 79% of range
$12.68 $48.35
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)52.38 · Neutral
Price Performance
1M+17.23%
3M+23.13%
6M+69.21%
1Y+193.11%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-24.60
Industry PE
25.88
Forward P/E
-26.84
PEG Ratio
-
Book Value
$4.59
Price to Book
8.66
P/S
-
EV/EBITDA
-19.14
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-36.44%
ROE
-38.14%
ROA
-25.64%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.46
EPS (TTM)
$-1.66

Balance Sheet & Liquidity

Debt/Equity
0.77
Quick Ratio
22.16
Current Ratio
22.61
Debt
$3.79M
Total Assets
$518.52M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
0.45%
Chg in Prom Hold
-
FII / Inst Holding
113.89%
Chg in FII Hold
0.01%

Financial Snapshot

Enterprise Value
$4.39B
Total Revenue (TTM)
-
EBITDA
$-197.45M
Free Cash Flow
$-90.52M
Operating Cash Flow
$-148.49M
Shares Outstanding
107.59M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 EWTX Edgewise Therapeutics, Inc. R2K 40.83 -24.60 $4.39B 0.00% -36.44% -38.14% - -
2 LLY Eli Lilly and Company SPX 1,156.63 41.13 $1.03T 0.60% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 247.02 28.66 $594.63B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.11 119.08 $431.29B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 418.52 31.54 $380.08B 2.18% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 123.61 34.82 $305.29B 2.82% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 168.37 26.10 $261.12B 1.87% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 535.29 29.40 $198.93B 0.35% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 358.32 24.92 $193.39B 2.80% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Operating Income -3.25M-3.96M-3.64M-6.86M-10.46M-13.08M-14.83M-16.49M-18.26M-25.70M-25.34M-29.45M-34.75M-38.11M-40.43M-45.96M-42.61M-46.86M-54.12M
Net Income -3.19M-3.95M-3.64M-6.82M-10.35M-12.95M-14.66M-16.07M-17.50M-22.84M-21.47M-25.71M-28.52M-31.50M-34.13M-40.80M-36.12M-40.67M-49.01M
Diluted EPS ----4.37-0.21-0.26-0.30-0.32-0.34-0.36-0.34-0.41-0.33-0.34-0.36-0.43-0.34-0.39-0.46
R&D Expense 2.97M3.64M3.24M5.36M7.86M9.88M11.12M12.40M13.89M19.88M19.56M23.79M27.69M30.68M32.22M36.76M33.56M37.48M42.65M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Income -17.19M-43.22M-71.66M-114.36M-158.83M-191.41M
Net Income -17.12M-42.81M-67.64M-100.16M-133.81M-167.79M
Diluted EPS -23.17-1.14-1.26-1.57-1.45-1.63
R&D Expense 14.98M32.19M54.03M90.91M126.97M151.39M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -131.14M285.23M367.10M340.04M486.82M552.60M
Total Equity -16.85M-33.42M274.38M346.72M318.83M459.22M522.26M
Cash & Equivalents -104.92M15.57M21.99M86.10M41.67M61.15M
Total Liabilities -4.34M10.85M20.39M21.20M27.60M30.35M
Current Liabilities -4.34M10.52M16.59M16.77M23.86M27.37M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -14.63M-33.51M-52.63M-91.95M-109.03M-143.82M
Investing Cash Flow -24.38M-242.23M-70.58M102.89M-184.66M-32.79M
Financing Cash Flow 120.28M186.38M129.64M53.17M249.25M196.09M
Capital Expenditure -203.00K-668.00K-5.55M-5.75M-1.31M-256.00K
Free Cash Flow -14.84M-34.17M-58.18M-97.69M-110.34M-144.07M

Ratios (Annual)

Figures in %.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ------
Operating Margin % ------
Net Margin % ------
ROE % 51.2%-15.6%-19.5%-31.4%-29.1%-32.1%
ROCE % -13.6%-15.7%-20.4%-35.4%-34.3%-36.4%

Shareholding Pattern

Insiders
0.45%
Institutions
113.89%
Public Float
114.41%

Top Institutional Holders

#Holder% HeldSharesValue
1 Orbimed Advisors LLC. 14.42% 15.52M $616.55M
2 RA Capital Management, L.P. 9.69% 10.43M $414.32M
3 Paradigm Biocapital Advisors LP 6.85% 7.37M $292.61M
4 Baker Bros. Advisors, LP 6.11% 6.58M $261.26M
5 Blackrock Inc. 6.02% 6.47M $257.17M
6 Janus Henderson Group PLC 5.50% 5.92M $235.03M
7 Novo Holdings A/S 4.97% 5.35M $212.56M
8 Driehaus Capital Management, LLC 4.16% 4.48M $177.91M
9 Siren, L.L.C. 4.12% 4.43M $176.01M
10 Perceptive Advisors Llc 4.11% 4.42M $175.76M

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for EWTX

Google News Mon, 13 Jul 2026

symbol__ Stock Quote Price and Forecast - CNN

<a href="https://news.google.com/rss/articles/CBMiUEFVX3lxTE4zelNXc0dkREJNRXFBcUM2N3JmdlgxRzVtMWdrZ1I5bnZLdF92WklnV0taQ0l6NTh0RTk0ekt0eEJDQ2VhN2lWNEpWQ1VhU3NQ?oc=5" target="_blank">symbol__ Stock Quote Price and Forecast</a>&nbsp;&nbsp;<fon…

Google News Mon, 13 Jul 2026

Biotech Edgewise banks $1.55B upfront, pivots fully to heart drugs - Stock Titan

<a href="https://news.google.com/rss/articles/CBMivAFBVV95cUxNNXNnenF3VEd3TlJ3MEltcXMxRW90MTFKYU5RMG11TndRTnlQMm9SNU9lck4wQ3lEbFNuVU9vMmR3VGpjXzZVSll0ZGdCRU9BUXNfeTBxeGVjcHZYY0VxY3lqVXh4ekpuVGdDbTNXZ3Fyb05RRFBJVmFRalQyWjJLMmYyaks2TUcwaFJJWF…

Google News Fri, 10 Jul 2026

Edgewise Therapeutics Stock Rides A 5-Day Winning Streak To A 23% Gain - Trefis

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Google News Mon, 22 Jun 2026

Edgewise Therapeutics (EWTX) Stock Looks Fully Priced After Phase 2 HCM Progress - simplywall.st

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Google News Mon, 13 Jul 2026

Positive Trial Results Propel Edgewise's (EWTX) Plans for Phase 3 Development - GuruFocus

<a href="https://news.google.com/rss/articles/CBMiswFBVV95cUxQenpLb0cteU5ENHpYb28xckdncGZhZFlhN25aWVdLMVQtd29ZSFo2ZGtIeTFPTk4tU0tHdkU3QU1rUV91LTFJRHJjckpEb1FlMEM5UHNQMURkZlF0T1FiU1EyVUV5aFo0NHNxbDBJaV9hWmY5UWdkWGVMaWxLRWl5RlRIUXpZcmowMlVKen…

Google News Mon, 29 Jun 2026

Is Edgewise Therapeutics, Inc. (EWTX) A Good Stock To Buy Now? - Yahoo Finance

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EWTX — Frequently Asked Questions

What is the current share price of Edgewise Therapeutics, Inc. (EWTX)?

As of 2026-07-15 16:51 PDT, Edgewise Therapeutics, Inc. (EWTX) trades at $40.83 on NasdaqGS. Its 52-week range is $12.68 to $48.35.

What is the market capitalisation of EWTX?

Edgewise Therapeutics, Inc. (EWTX) has a market capitalisation of $4.39B on NasdaqGS.

What is the P/E ratio of EWTX?

EWTX trades at a trailing price-to-earnings (P/E) ratio of -24.60. The industry average P/E is 25.88. Its price-to-book (P/B) ratio is 8.66.

What is the return on equity (ROE) of EWTX?

EWTX has a return on equity (ROE) of -38.14%. Its return on capital employed (ROCE) is -36.44%.

Is EWTX a good stock to buy?

This page provides a data-driven analysis of Edgewise Therapeutics, Inc. (EWTX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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