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Precision BioSciences, Inc. DTIL PHARMA

Healthcare · Biotechnology · United States
https://precisionbiosciences.com
Company Profile ↓
$7.40
+57.78% 1Y
Mkt Cap$204.25M
P/E-5.61
P/B4.23
52W High$9.28
52W Low$3.57
Book Value$1.71
EPS (TTM)$-1.32

Company Overview

Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, as well as to inactivate integrated HBV DNA with the goal of long-lasting reductions in hepatitis B surface antigen; and PBGENE-DMD (Excision) for the treatment of Duchenne muscular dystrophy. In addition, the company develops PBGENE-3243 for the treatment of m.3243 associated mitochondrial diseases; and iECURE-OTC (Insertion) for ornithine transcarbamylase deficiency. It has collaboration agreements with TG Cell Therapy, Inc. to develop, manufacture, and commercialize azercabtagene zapreleucel for autoimmune diseases and other indications; and iECURE, Inc., an ARCUS-mediated targeted gene insertion. Precision BioSciences, Inc. was incorporated in 2006 and is headquartered in Durham, North Carolina.

Why Investors Should Care

Steady Revenue Expansion

Revenue has grown at a 17.8% CAGR over the past five years.

Recent Developments

  • Dec 2025 Revenue of $34.26M (-50.1% YoY); net profit $-45.72M.
  • Trailing 12 Months Year-on-year growth — revenue -50.1%, earnings -738.0%.
  • 5-Year Trend Long-term compounding — revenue CAGR 17.8%.

Growth & Price Performance

Compounded Sales Growth

5 Years:17.80%
1 Year:-50.12%

Compounded Profit Growth

5 Years:-
1 Year:-737.98%

Stock Price Performance

1 Year:+57.78%
6 Months:+57.11%
3 Months:+9.31%
1 Month:-1.20%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Mixed
52-Week Range 67% of range
$3.57 $9.28
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMAAbove
  • RSI (14)41.83 · Neutral
Price Performance
1M-1.20%
3M+9.31%
6M+57.11%
1Y+57.78%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Compounding revenue at 17.8% over 5 years.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-5.61
Industry PE
24.83
Forward P/E
-3.98
PEG Ratio
-
Book Value
$1.71
Price to Book
4.23
P/S
4.44
EV/EBITDA
-4.12
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
17.80%
Profit 5Y
-
Revenue (YoY)
-50.12%
Earnings (YoY)
-737.98%

Profitability & Returns

ROCE
-35.84%
ROE
-135.15%
ROA
-19.37%
Profit Margin
-
Op Margin
-80.78%
Gross Margin
100.00%
EPS (Latest Qtr)
$-1.26
EPS (TTM)
$-1.32

Balance Sheet & Liquidity

Debt/Equity
0.62
Quick Ratio
12.26
Current Ratio
12.82
Debt
$28.10M
Total Assets
$125.92M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
8.02%
Chg in Prom Hold
1.84%
FII / Inst Holding
68.71%
Chg in FII Hold
0.03%

Financial Snapshot

Enterprise Value
$204.25M
Total Revenue (TTM)
$45.05M
EBITDA
$-35.15M
Free Cash Flow
$-16.25M
Operating Cash Flow
$-51.90M
Shares Outstanding
27.60M
Gross Margin
100.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 DTIL Precision BioSciences, Inc. PHARMA 7.40 -5.61 $204.25M 0.00% -35.84% -135.15% 17.80% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,123.91 37.80 $1.00T 0.60% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 269.12 31.22 $648.55B 1.98% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 248.78 70.48 $439.62B 2.78% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 148.46 118.77 $366.28B 2.31% - 6.96% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 400.84 25.74 $359.79B 2.47% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 137.70 20.80 $261.73B 3.36% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 160.04 23.99 $248.20B 2.00% 15.97% 21.96% 9.82% 45.96%
9 TMO Thermo Fisher Scientific Inc. SPXR3KPHARMA 603.02 32.49 $222.97B 0.29% 8.14% 13.51% 8.81% 12.95%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2018Jun 2018Sep 2018Mar 2019Jun 2019Sep 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue 1.53M1.87M2.54M5.46M5.39M4.87M7.00M1.08M7.36M16.35M68.81M24.04M3.32M3.82M7.36M8.78M19.79M13.12M17.58M49.90M576.00K29.00K18.00K13.00K10.84M0
Operating Income -9.23M-12.12M-10.45M-19.49M-23.87M-21.98M-27.50M-32.81M-26.04M-18.74M21.63M-11.54M-27.34M-29.55M-14.68M-13.35M-3.13M-12.36M-4.19M24.15M-21.27M-22.11M-21.88M-20.67M-9.07M-19.16M
Net Income -9.01M-11.83M-9.76M-31.78M-19.44M-20.74M-26.84M-32.70M-26.02M-18.69M21.66M-11.28M-28.17M-31.04M-23.95M-25.06M-11.89M-8.08M8.59M32.75M-16.43M-20.57M-23.52M-21.77M-18.44M-32.65M
Diluted EPS --------0.63--0.36-0.19-0.46-0.46-0.22-6.75-3.13-2.101.704.67-2.25-2.21-2.13-1.84-0.75-1.26
R&D Expense 8.12M10.87M9.74M19.96M22.76M19.79M24.88M25.18M24.87M25.59M37.23M25.94M19.97M22.94M11.76M11.05M13.09M15.85M13.34M17.23M13.08M13.59M12.77M13.35M13.11M12.39M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 10.88M22.24M24.29M115.53M25.10M48.73M68.70M34.26M
Operating Income -47.91M-87.20M-109.83M-39.38M-62.31M-43.74M-26.16M-52.15M
Net Income -46.04M-92.88M-109.01M-30.60M-111.64M-61.32M7.17M-45.72M
Diluted EPS ----0.52-38.10-15.961.04-3.56
R&D Expense 45.12M82.42M98.06M115.24M46.12M53.38M59.56M54.17M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -138.60M235.23M150.16M211.50M238.17M159.78M136.39M154.42M
Total Equity -26.37M39.96M138.31M44.42M91.17M60.43M18.86M56.39M92.25M
Cash & Equivalents -103.19M180.89M89.80M143.66M189.58M116.68M85.90M110.82M
Long Term Debt ----2.48M22.22M---
Total Liabilities -98.64M96.92M105.73M120.33M177.74M140.92M80.00M62.17M
Current Liabilities -14.07M26.93M42.83M35.98M59.66M49.99M14.98M8.91M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -51.72M-71.02M-87.39M-10.85M-45.75M-84.11M-58.45M-65.84M
Investing Cash Flow -15.66M-24.67M-5.03M-5.80M-3.32M5.83M-215.00K-634.00K
Financing Cash Flow 107.78M173.37M1.33M70.52M94.98M5.39M50.45M95.16M

Ratios (Annual)

Figures in %.

Metric Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % --------
Operating Margin % -440.2%-392.1%-452.2%-34.1%-248.3%-89.8%-38.1%-152.2%
Net Margin % -423.0%-417.6%-448.9%-26.5%-444.8%-125.8%10.4%-133.4%
ROE % -115.2%-67.1%-245.4%-33.6%-184.7%-325.1%12.7%-49.6%
ROCE % -38.5%-41.9%-102.3%-22.4%-34.9%-39.8%-21.5%-35.8%

Shareholding Pattern

Insiders
8.02%
Institutions
68.71%
Public Float
74.70%

Top Institutional Holders

#Holder% HeldSharesValue
1 Aberdeen Group plc 8.08% 2.23M $14.88M
2 Bleichroeder LP 7.31% 2.02M $13.46M
3 Octagon Capital Advisors LP 4.89% 1.35M $9.00M
4 Boothbay Fund Management, LLC 4.88% 1.35M $8.98M
5 Blackrock Inc. 4.25% 1.17M $7.82M
6 Vanguard Capital Management LLC 4.04% 1.12M $7.45M
7 Lynx1 Capital Management Lp 3.44% 950.47K $6.34M
8 Driehaus Capital Management, LLC 3.43% 946.71K $6.31M
9 Empery Asset Management, LP 2.81% 776.09K $5.18M
10 Affinity Asset Advisors, Llc 2.34% 646.58K $4.31M

Analyst View

Loading analyst coverage…

Latest News

Recent headlines for DTIL

Google News Sat, 05 Sep 2026

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Google News Sun, 06 Sep 2026

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Google News ue, 18 Aug 2026

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Google News Mon, 24 Aug 2026

A gene-editing treatment for Duchenne muscular dystrophy doses its first patient - Stock Titan

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DTIL — Frequently Asked Questions

What is the current share price of Precision BioSciences, Inc. (DTIL)?

As of 2026-09-19 21:16 PDT, Precision BioSciences, Inc. (DTIL) trades at $7.40 on NasdaqCM. Its 52-week range is $3.57 to $9.28.

What is the market capitalisation of DTIL?

Precision BioSciences, Inc. (DTIL) has a market capitalisation of $204.25M on NasdaqCM.

What is the P/E ratio of DTIL?

DTIL trades at a trailing price-to-earnings (P/E) ratio of -5.61. The industry average P/E is 24.83. Its price-to-book (P/B) ratio is 4.23.

What is the return on equity (ROE) of DTIL?

DTIL has a return on equity (ROE) of -135.15%. Its return on capital employed (ROCE) is -35.84%.

Is DTIL a good stock to buy?

This page provides a data-driven analysis of Precision BioSciences, Inc. (DTIL), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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