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Definium Therapeutics, Inc. DFTX R2K

Healthcare · Biotechnology · United States
https://definiumtx.com
Company Profile ↓
$45.98
+451.98% 1Y
Mkt Cap$5.01B
P/E-18.39
P/B7.36
52W High$48.45
52W Low$8.07
Book Value$3.36
EPS (TTM)$-2.50

Company Overview

Definium Therapeutics, Inc., a clinical biopharmaceutical company, develops novel product candidates to treat brain health disorders. The company's lead product candidates DT120, which is in phase 3 for the treatment of generalized anxiety disorder, major depressive disorder, and other brain health disorders; and DT402, a R-enantiomer of 3,4-methylenedioxymethamphetamine, which is in phase 2a clinical trials for the treatment of autism spectrum disorder. The company was formerly known as Mind Medicine (MindMed) Inc. and changed its name to Definium Therapeutics, Inc. in January 2026. Definium Therapeutics, Inc. is headquartered in New York, New York.

Why Investors Should Care

Conservative Balance Sheet

Carries low leverage with a debt-to-equity ratio of 0.15.

Growth & Price Performance

Stock Price Performance

1 Year:+451.98%
6 Months:+232.23%
3 Months:+106.65%
1 Month:+90.71%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 94% of range
$8.07 $48.45
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)67.94 · Neutral
Price Performance
1M+90.71%
3M+106.65%
6M+232.23%
1Y+451.98%

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
-18.39
Industry PE
25.41
Forward P/E
-29.08
PEG Ratio
-
Book Value
$3.36
Price to Book
7.36
P/S
-
EV/EBITDA
-
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
-
Profit 5Y
-
Revenue (YoY)
-
Earnings (YoY)
-

Profitability & Returns

ROCE
-44.54%
ROE
-94.70%
ROA
-35.72%
Profit Margin
0.00%
Op Margin
0.00%
Gross Margin
0.00%
EPS (Latest Qtr)
$-0.71
EPS (TTM)
$-2.50

Balance Sheet & Liquidity

Debt/Equity
0.15
Quick Ratio
4.60
Current Ratio
4.69
Debt
$40.77M
Total Assets
$401.29M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
1.33%
Chg in Prom Hold
0.05%
FII / Inst Holding
65.58%
Chg in FII Hold
0.00%

Financial Snapshot

Enterprise Value
$5.01B
Total Revenue (TTM)
-
EBITDA
-
Free Cash Flow
$-45.63M
Operating Cash Flow
$-144.77M
Shares Outstanding
109.07M
Gross Margin
0.00%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 DFTX Definium Therapeutics, Inc. R2K 45.98 -18.39 $5.01B 0.00% -44.54% -94.70% - -
2 LLY Eli Lilly and Company SPX 1,152.54 41.02 $1.03T 0.61% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 253.85 29.45 $611.07B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.78 119.40 $432.48B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 425.19 32.02 $386.13B 2.27% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 120.78 34.02 $298.31B 2.86% - 18.94% 5.64% 10.01%
7 AZN AstraZeneca PLC NDX 164.50 24.81 $255.12B 1.77% 15.97% 23.48% 9.82% 45.96%
8 TMO Thermo Fisher Scientific Inc. SPX 534.07 29.33 $198.47B 0.40% 8.14% 13.52% 8.81% 12.95%
9 AMGN Amgen Inc. NDXSPX 355.25 24.69 $191.73B 2.84% 18.02% 101.32% 11.77% 5.58%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026
Operating Income -13.85M-45.22M-17.23M-18.50M-16.94M-16.98M-20.86M-29.18M-21.62M-22.20M-24.46M-24.79M-32.16M-40.90M-45.67M-59.22M
Net Income -13.76M-45.25M-17.20M-18.45M-16.96M-16.48M-24.82M-29.13M-17.92M-54.40M-5.85M-13.68M-23.35M-42.74M-67.27M-77.10M
Diluted EPS --0.11-0.61-0.66-0.60-0.56-0.65-0.76-0.45-1.14-0.26-0.27-0.35-0.50-0.78-0.71
R&D Expense 6.81M8.07M9.02M10.24M9.33M7.77M12.60M14.78M13.20M11.71M14.64M17.19M23.36M29.81M30.98M41.48M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Income -33.03M-93.85M-66.33M-93.87M-103.92M-166.31M
Net Income -33.94M-93.04M-56.80M-95.73M-108.68M-183.79M
Diluted EPS --3.40-1.84-2.44-1.54-2.06
R&D Expense 18.63M34.79M36.17M52.12M65.30M117.67M

Balance Sheet (Annual)

Figures in USD.

Metric May 2019Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --81.52M164.00M169.99M124.54M302.15M440.10M
Total Equity 04.78M75.87M151.66M150.92M78.13M241.45M332.33M
Cash & Equivalents --80.09M133.54M142.14M99.70M273.74M257.84M
Long Term Debt -----14.13M21.85M40.58M
Total Liabilities --5.65M12.34M19.08M46.41M60.70M107.77M
Current Liabilities --3.01M10.41M17.89M32.25M38.85M66.70M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -23.60M-45.82M-50.14M-64.36M-79.13M-131.56M
Investing Cash Flow --297.00K--0-151.61M
Financing Cash Flow 96.70M98.82M59.05M21.85M253.20M267.27M

Ratios (Annual)

Figures in %.

Metric Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % ------
Operating Margin % ------
Net Margin % ------
ROE % -44.7%-61.3%-37.6%-122.5%-45.0%-55.3%
ROCE % -42.1%-61.1%-43.6%-101.7%-39.5%-44.5%

Shareholding Pattern

Insiders
1.33%
Institutions
65.58%
Public Float
66.46%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 7.78% 8.48M $376.69M
2 Driehaus Capital Management, LLC 5.42% 5.91M $262.61M
3 Avoro Capital Advisors LLC 4.58% 5.00M $222.10M
4 Janus Henderson Group PLC 3.26% 3.56M $157.96M
5 Deep Track Capital, Lp 2.75% 3.00M $133.26M
6 Geode Capital Management, LLC 2.29% 2.50M $110.85M
7 State Street Corporation 2.27% 2.47M $109.80M
8 Octagon Capital Advisors LP 2.24% 2.44M $108.38M
9 Commodore Capital Lp 1.83% 2.00M $88.84M
10 FMR, LLC 1.66% 1.81M $80.38M

Analyst View

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Latest News

Recent headlines for DFTX

Google News ue, 14 Jul 2026

DFTX Vs CMPS: Which Stock Has More Upside From Trump’s New Psychedelic Therapy Push? - Stocktwits

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Google News Mon, 13 Jul 2026

symbol__ Stock Quote Price and Forecast - CNN

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Google News ue, 30 Jun 2026

Is Definium Therapeutics, Inc. (DFTX) Stock Poised for Further Gains After Positive Emerge Trial Update? - Yahoo Finance

<a href="https://news.google.com/rss/articles/CBMingFBVV95cUxNQmU5eFJXRE5LWkx6REhpVWpRTkF3OVlKbFppWUoyM25kTGNWR29TZFpCc3ZTQnU0Mm1MS2VscDVMZmdQakxOYzZTTGx4anh4ZWl1d0JEQ213YkdKZ2NMdnRqUnFFS29QelZMcUU0dXZCamozQVVjdHhVQjg4QmhTdEF1TmJxTmdFd2gyY3…

Google News Mon, 13 Jul 2026

$DFTX stock is down 6% today. Here's what we see in our data. - Quiver Quantitative

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Google News ue, 14 Jul 2026

Will New GAD Treatment Persistence Data Change Definium Therapeutics' (DFTX) Unmet‑Need Narrative? - simplywall.st

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Google News ue, 14 Jul 2026

More Than Half of Newly Diagnosed GAD Patients Stopped Therapy - Stock Titan

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DFTX — Frequently Asked Questions

What is the current share price of Definium Therapeutics, Inc. (DFTX)?

As of 2026-07-14 21:23 PDT, Definium Therapeutics, Inc. (DFTX) trades at $45.98 on NasdaqGS. Its 52-week range is $8.07 to $48.45.

What is the market capitalisation of DFTX?

Definium Therapeutics, Inc. (DFTX) has a market capitalisation of $5.01B on NasdaqGS.

What is the P/E ratio of DFTX?

DFTX trades at a trailing price-to-earnings (P/E) ratio of -18.39. The industry average P/E is 25.41. Its price-to-book (P/B) ratio is 7.36.

What is the return on equity (ROE) of DFTX?

DFTX has a return on equity (ROE) of -94.70%. Its return on capital employed (ROCE) is -44.54%.

Is DFTX a good stock to buy?

This page provides a data-driven analysis of Definium Therapeutics, Inc. (DFTX), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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