Company Overview
Cardiff Oncology, Inc., a clinical-stage biotechnology company, develops novel therapies for the treatment of various cancers in the United States. Its lead drug candidate is Onvansertib, an oral and selective polo-like kinase 1 inhibitor for treating RAS-mutated metastatic colorectal cancer. The company also focuses on the clinical program in indications, such as investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma, small cell lung cancer, metastatic triple negative breast cancer, and chronic myelomonocytic leukemia; CRDF-004, a Phase 2 open-label randomized multi-center clinical trial of onvansertib in combination with FOLFIRI and bevacizumab or FOLFOX and bevacizumab for the treatment of patients confirmed metastatic and unresectable colorectal cancer in patients with a KRAS or NRAS mutation; and TROV-054, a Phase 1b/2 single-arm clinical trial in KRAS-mutated metastatic colorectal cancer. The company was formerly known as Trovagene, Inc. and changed its name to Cardiff Oncology, Inc. in May 2012. Cardiff Oncology, Inc. was founded in 1999 and is headquartered in San Diego, California.
Recent Developments
- Dec 2025 Revenue of $593.00K (-13.2% YoY); net profit $-45.85M.
- Trailing 12 Months Year-on-year growth — revenue -62.4%.
- 5-Year Trend Long-term compounding — revenue CAGR 6.6%.
Growth & Price Performance
Compounded Sales Growth
| 5 Years: | 6.62% |
| 1 Year: | -62.40% |
Stock Price Performance
| 1 Year: | -68.28% |
| 6 Months: | -57.47% |
| 3 Months: | -17.61% |
| 1 Month: | -17.61% |
Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.
- Price vs 50-DMABelow
- Price vs 200-DMABelow
- RSI (14)45.63 · Neutral
Auto-generated from price history and fundamentals; not investment advice.
Price Chart
Technical Trend
Computed from daily close history using EMA cross, slope, and RSI signals.
Note: intraday data is not stored locally. “Hourly” uses the most recent 10 daily candles as a short-term proxy.
Fundamental Growth Charts
No fundamental data available for this stock.
Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.
PROS
No notable strengths flagged.
CONS
- Trading 70.6% below its 52-week high.
- In a downtrend (50-DMA below 200-DMA).
* The pros and cons are auto-generated from financial metrics.
Valuation
Growth (CAGR)
Profitability & Returns
Balance Sheet & Liquidity
Ownership
Financial Snapshot
Peer comparison
Peer companies in the same sector (Healthcare).
| # | Name | CMP $ | P/E | Mkt Cap | Div Yld % | ROCE % | ROE % | Rev CAGR 5Y % | Profit CAGR 5Y % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | CRDF Cardiff Oncology, Inc. R2K | 1.31 | -1.96 | $89.56M | 0.00% | -107.63% | -84.79% | 6.62% | - |
| 2 | LLY Eli Lilly and Company SPX | 1,152.54 | 41.02 | $1.03T | 0.61% | - | 107.46% | 7.20% | 11.41% |
| 3 | JNJ Johnson & Johnson SPX | 253.85 | 29.45 | $611.07B | 2.23% | 14.88% | 26.42% | 2.43% | 4.76% |
| 4 | ABBV AbbVie Inc. SPX | 244.78 | 119.40 | $432.48B | 3.04% | 10.47% | -129.24% | 1.75% | -29.06% |
| 5 | UNH UnitedHealth Group Incorporated SPX | 425.19 | 32.02 | $386.13B | 2.27% | 9.74% | 12.18% | 10.40% | 5.43% |
| 6 | MRK Merck & Co., Inc. SPX | 120.78 | 34.02 | $298.31B | 2.86% | - | 18.94% | 5.64% | 10.01% |
| 7 | AZN AstraZeneca PLC NDX | 164.50 | 24.81 | $255.12B | 1.77% | 15.97% | 23.48% | 9.82% | 45.96% |
| 8 | TMO Thermo Fisher Scientific Inc. SPX | 534.07 | 29.33 | $198.47B | 0.40% | 8.14% | 13.52% | 8.81% | 12.95% |
| 9 | AMGN Amgen Inc. NDXSPX | 355.25 | 24.69 | $191.73B | 2.84% | 18.02% | 101.32% | 11.77% | 5.58% |
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios
Quarterly Results
Figures in USD.
| Metric | Jun 2014 | Sep 2014 | Dec 2014 | Mar 2015 | Jun 2015 | Sep 2015 | Dec 2015 | Mar 2016 | Jun 2016 | Sep 2016 | Dec 2016 | Mar 2017 | Jun 2017 | Sep 2017 | Dec 2017 | Mar 2018 | Jun 2018 | Sep 2018 | Mar 2019 | Jun 2019 | Sep 2019 | Mar 2020 | Jun 2020 | Sep 2020 | Mar 2021 | Jun 2021 | Sep 2021 | Mar 2022 | Jun 2022 | Sep 2022 | Mar 2023 | Jun 2023 | Sep 2023 | Mar 2024 | Jun 2024 | Sep 2024 | Mar 2025 | Jun 2025 | Sep 2025 | Mar 2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 62.02K | 36.85K | 51.69K | 68.00K | 43.00K | 136.00K | 72.00K | 68.00K | 86.00K | 74.00K | 91.00K | 93.00K | 83.00K | 108.00K | 141.00K | 205.00K | 163.00K | 165.00K | 109.00K | 121.00K | 120.00K | 41.00K |
| Operating Income | -3.24M | -3.94M | - | -4.85M | -6.63M | -6.41M | - | -10.46M | -9.98M | -9.92M | - | -10.13M | -5.89M | -5.80M | - | -4.66M | -4.44M | -3.86M | -3.96M | -4.22M | -4.21M | -4.12M | -4.10M | -4.36M | -5.44M | -6.89M | -7.00M | -11.07M | -10.44M | -8.99M | -12.05M | -12.21M | -10.82M | -10.93M | -12.54M | -12.60M | -14.38M | -14.78M | -11.97M | -12.85M |
| Net Income | -1.08M | -5.38M | - | -7.17M | -10.18M | -2.74M | - | -10.26M | -10.20M | -10.19M | - | -10.00M | -8.05M | -4.29M | - | -4.79M | -3.75M | -3.77M | -3.90M | -4.13M | -4.14M | -4.09M | -4.12M | -4.50M | -5.18M | -6.76M | -6.91M | -10.99M | -10.44M | -8.57M | -11.22M | -11.15M | -9.73M | -10.01M | -11.78M | -11.86M | -13.43M | -13.94M | -11.26M | -12.35M |
| Diluted EPS | -0.17 | -0.28 | -0.25 | -0.33 | -0.41 | -0.23 | -0.26 | -0.36 | -0.34 | -0.34 | -0.34 | -0.32 | -3.12 | -1.41 | -0.06 | -6.23 | -5.27 | -1.10 | -1.02 | -0.79 | -0.71 | - | -0.51 | -0.19 | -0.14 | -0.17 | -0.17 | -0.25 | -0.24 | -0.20 | -0.25 | -0.25 | -0.22 | -0.22 | -0.26 | -0.25 | -0.20 | -0.21 | -0.17 | -0.18 |
Profit & Loss (Annual)
Figures in USD.
| Metric | Jan 2001 | Jan 2002 | Jan 2003 | Jan 2004 | Jan 2005 | Jan 2006 | Jan 2007 | Dec 2007 | Dec 2008 | Dec 2009 | Dec 2010 | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | - | - | - | - | - | - | - | - | - | - | - | 257.70K | 450.40K | 259.25K | 280.18K | 312.81K | 381.07K | 505.40K | 378.32K | 244.63K | 366.00K | - | 386.00K | 488.00K | 683.00K | 593.00K |
| Cost of Revenue | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Gross Profit | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Operating Expenses | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 40.29M | 45.90M | 49.33M | 49.55M |
| Operating Income | - | - | - | - | - | - | - | - | - | - | - | -2.98M | -4.85M | -10.69M | -14.95M | -25.27M | -40.15M | -25.60M | -17.05M | -16.68M | -19.09M | - | -39.90M | -45.41M | -48.65M | -48.96M |
| EBITDA | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -39.67M | -45.01M | -47.71M | -48.06M |
| Interest Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | - | - | - | - |
| Pretax Income | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -38.70M | -41.44M | -45.43M | -45.85M |
| Tax Provision | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Net Income | -267.60K | -524.22K | -481.61K | -383.02K | -5.37M | -7.84M | -7.13M | -4.68M | -5.17M | -2.48M | -5.45M | -2.24M | -11.57M | -11.81M | -14.33M | -27.47M | -39.20M | -24.91M | -16.46M | -16.41M | -19.31M | - | -38.70M | -41.44M | -45.43M | -45.85M |
| Diluted EPS | - | - | - | - | - | - | - | - | - | - | - | - | -0.89 | -0.70 | -0.88 | -1.21 | -1.37 | -51.76 | -8.26 | - | -1.08 | - | -0.89 | -0.93 | -0.95 | -0.69 |
| R&D Expense | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 11.24M | 17.40M | 27.10M | - | - | - |
Balance Sheet (Annual)
Figures in USD.
| Metric | Jan 2000 | Jan 2001 | Jan 2002 | Jan 2003 | Jan 2004 | Jan 2005 | Jan 2006 | Jan 2007 | Dec 2007 | Dec 2008 | Dec 2009 | Dec 2010 | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Assets | - | - | - | - | - | - | - | - | - | - | - | - | 1.04M | 11.67M | 27.16M | 28.90M | 71.45M | 43.95M | 12.28M | 14.17M | 13.09M | 134.73M | 149.54M | 116.19M | 81.64M | 97.19M | 61.88M |
| Total Equity | 27.24K | -240.36K | -719.39K | -1.20M | -1.58M | 3.19M | 3.48M | 1.13M | -1.65M | -4.05M | -3.79M | -5.00M | -4.23M | 2.17M | 20.39M | 8.35M | 48.70M | 19.77M | 6.51M | 10.08M | 7.31M | 128.16M | 140.42M | 106.34M | 69.74M | 82.95M | 45.39M |
| Cash & Equivalents | - | - | - | - | - | - | - | - | - | - | - | 58.70K | 700.37K | 10.82M | 25.84M | 27.29M | 67.49M | 13.92M | 8.23M | 11.45M | 10.20M | 130.98M | 11.94M | 16.35M | 21.66M | 51.47M | 17.47M |
| Total Liabilities | - | - | - | - | - | - | - | - | - | - | - | - | 5.27M | 9.50M | 6.76M | 20.55M | 22.74M | 24.18M | 5.78M | 4.09M | 5.78M | 6.57M | 9.13M | 9.85M | 11.90M | 14.24M | 16.50M |
| Current Liabilities | - | - | - | - | - | - | - | - | - | - | - | - | 1.43M | 730.37K | 2.01M | 4.49M | 8.20M | 7.80M | 3.95M | 2.92M | 4.78M | 6.12M | 6.56M | 7.81M | 10.44M | 13.43M | 16.39M |
Cash Flows (Annual)
Figures in USD.
| Metric | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | - | - | - | - | - | - | - | -13.20M | -13.27M | -16.32M | -23.04M | -33.82M | -30.89M | -37.69M | -37.92M |
| Investing Cash Flow | - | - | - | - | - | - | - | 22.84K | -67.62K | -211.00K | -131.45M | 38.15M | 36.20M | 13.73M | 1.34M |
| Financing Cash Flow | - | - | - | - | - | - | - | 16.40M | 12.08M | 137.31M | 35.45M | 75.00K | 0 | 53.78M | 2.58M |
| Capital Expenditure | -1.53K | -274.08K | -649.78K | -363.29K | -2.24M | -823.48K | -101.10K | -5.10K | -67.62K | -211.00K | -205.00K | -1.01M | -582.00K | -80.00K | -44.00K |
| Free Cash Flow | - | - | - | - | - | - | - | -13.20M | -13.34M | -16.53M | -23.25M | -34.83M | -31.47M | -37.77M | -37.97M |
Ratios (Annual)
Figures in %.
| Metric | Jan 2001 | Jan 2002 | Jan 2003 | Jan 2004 | Jan 2005 | Jan 2006 | Jan 2007 | Dec 2007 | Dec 2008 | Dec 2009 | Dec 2010 | Dec 2011 | Dec 2012 | Dec 2013 | Dec 2014 | Dec 2015 | Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin % | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Operating Margin % | - | - | - | - | - | - | - | - | - | - | - | -1,155.2% | -1,076.6% | -4,123.7% | -5,334.2% | -8,079.5% | -10,534.9% | -5,064.4% | -4,507.6% | -6,817.8% | -5,214.8% | - | -10,337.3% | -9,305.7% | -7,123.1% | -8,256.3% |
| Net Margin % | - | - | - | - | - | - | - | - | - | - | - | -868.9% | -2,567.9% | -4,555.9% | -5,113.0% | -8,782.0% | -10,287.7% | -4,928.1% | -4,351.1% | -6,709.7% | -5,275.1% | - | -10,026.9% | -8,492.0% | -6,651.7% | -7,732.0% |
| ROE % | 111.3% | 72.9% | 40.3% | 24.3% | -168.3% | -225.4% | -631.5% | 284.6% | 127.6% | 65.6% | 109.1% | 52.9% | -533.2% | -57.9% | -171.6% | -56.4% | -198.3% | -382.8% | -163.2% | -224.5% | -15.1% | - | -36.4% | -59.4% | -54.8% | -101.0% |
| ROCE % | - | - | - | - | - | - | - | - | - | - | - | 762.1% | -44.3% | -42.5% | -61.2% | -40.0% | -111.0% | -306.9% | -151.6% | -200.8% | -14.8% | - | -36.8% | -63.8% | -58.1% | -107.6% |
Shareholding Pattern
Top Institutional Holders
| # | Holder | % Held | Shares | Value |
|---|---|---|---|---|
| 1 | Blackrock Inc. | 5.82% | 3.98M | $5.16M |
| 2 | Vanguard Capital Management LLC | 4.18% | 2.86M | $3.70M |
| 3 | Laurion Capital Management, LP | 3.87% | 2.65M | $3.43M |
| 4 | Pfizer Inc | 3.53% | 2.41M | $3.12M |
| 5 | Acorn Capital Advisors, LLC | 2.58% | 1.76M | $2.28M |
| 6 | Geode Capital Management, LLC | 2.34% | 1.60M | $2.07M |
| 7 | Franklin Resources, Inc. | 1.76% | 1.21M | $1.56M |
| 8 | State Street Corporation | 1.74% | 1.19M | $1.54M |
| 9 | BLAIR WILLIAM & CO/IL | 1.35% | 922.41K | $1.19M |
| 10 | FLPutnam Investment Management Company | 0.87% | 595.13K | $770.69K |
Analyst View
Analyst aggregate. Targets and ratings update periodically; not investment advice.
Latest News
Recent headlines for CRDF
Is Cardiff Oncology, Inc. (CRDF) Stock Undervalued Amid Legal Uncertainty and Future Cancer Drug Potential? - Yahoo Finance
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CRDF Forecast — Price Target — Prediction for 2027 - TradingView
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Cardiff Oncology (CRDF) director Gary W. Pace buys 30,000 shares in open market - Stock Titan
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Cardiff Oncology (CRDF) Faces Downgrade Amid Phase II Study Upda - GuruFocus
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Cardiff Oncology to Host Investor Webcast on June 3 for CRDF-004 Data Update in RAS-Mutated Metastatic Colorectal Cancer Trial - Quiver Quantitative
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H.C. Wainwright cuts Cardiff Oncology stock rating on license termination - Investing.com
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CRDF — Frequently Asked Questions
What is the current share price of Cardiff Oncology, Inc. (CRDF)?
As of 2026-07-14 21:23 PDT, Cardiff Oncology, Inc. (CRDF) trades at $1.31 on NasdaqCM. Its 52-week range is $1.18 to $4.45.
What is the market capitalisation of CRDF?
Cardiff Oncology, Inc. (CRDF) has a market capitalisation of $89.56M on NasdaqCM.
What is the P/E ratio of CRDF?
CRDF trades at a trailing price-to-earnings (P/E) ratio of -1.96. The industry average P/E is 25.41. Its price-to-book (P/B) ratio is 3.03.
What is the return on equity (ROE) of CRDF?
CRDF has a return on equity (ROE) of -84.79%. Its return on capital employed (ROCE) is -107.63%.
Is CRDF a good stock to buy?
This page provides a data-driven analysis of Cardiff Oncology, Inc. (CRDF), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.