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CareDx, Inc. CDNA R2KR3KPHARMA

Healthcare · Diagnostics & Research · United States
https://caredx.com
Company Profile ↓
$50.88
+319.46% 1Y
Mkt Cap$2.63B
P/E24.46
P/B5.65
52W High$52.36
52W Low$11.57
Book Value$8.27
EPS (TTM)$2.08

Company Overview

CareDx, Inc. provides solutions for improving outcomes for transplant patients and advancing organ health in the United States and internationally. The company provides AlloSure Kidney, a donor-derived cell-free DNA (dd-cfDNA) solution for kidney transplant patients; AlloMap Heart, a gene expression profiling solution for heart transplant patients; AlloSure Heart, a dd-cfDNA solution for heart transplant patients; and AlloSure Lung, a dd-cfDNA solution for lung transplant patients. It also offers HeartCare, which provides information about distinct biological processes, such as immune quiescence, active injury, acute cellular rejection, and antibody mediated rejection; HistoMap Kidney, a solution that identifies allograft rejection and type of rejection in kidney transplant biopsy tissue; and AlloHeme, a monitoring test that predicts relapse in patients with acute myeloid leukemia and myelodysplastic syndromes. In addition, the company provides QTYPE that enables precision in human leukocyte antigen (HLA) typing; Olerup SSP, which is used to type HLA alleles based on sequence specific primer technology; and Ottr, a transplant patient management software. Further, it offers AlloSeq Tx, a high-resolution HLA typing solution; AlloSeq cfDNA, a surveillance solution to measure dd-cfDNA in blood; AlloSeq HCT, a solution for chimerism testing for stem cell transplant recipients; Allocell, a solution that monitors the pharmacokinetics of engraftment and persistence of cells for patients who have received allogeneic cell therapy; and XynQAPI, MedActionPlan, CareDx pharmacy, AlloHome, and HLA Data Systems software solutions. It has a license agreement with Illumina, Inc. for the distribution, development, and commercialization of NGS products and technologies. The company was formerly known as XDx, Inc. and changed its name to CareDx, Inc. in March 2014. The company was incorporated in 1998 and is headquartered in Brisbane, California.

Why Investors Should Care

Strong Return on Equity

Generates a return on equity of 29.5%, reflecting efficient use of shareholder capital.

Steady Revenue Expansion

Revenue has grown at a 25.2% CAGR over the past five years.

Reasonable Valuation

Trades at a P/E of 24.5, below the sector median of 25.2.

Healthy Margins

Maintains a net profit margin of 24.2%.

Positive Free Cash Flow

Generates positive free cash flow, funding growth and shareholder returns internally.

Recent Developments

  • Dec 2025 Revenue of $379.81M (+13.8% YoY); net profit $-21.35M.
  • Trailing 12 Months Year-on-year growth — revenue +52.2%, earnings -140.6%.
  • 5-Year Trend Long-term compounding — revenue CAGR 25.2%.

Growth & Price Performance

Compounded Sales Growth

5 Years:25.20%
1 Year:52.20%

Compounded Profit Growth

5 Years:-
1 Year:-140.64%

Stock Price Performance

1 Year:+319.46%
6 Months:+184.40%
3 Months:+128.67%
1 Month:+13.55%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bullish
52-Week Range 96% of range
$11.57 $52.36
Trend Signals
  • Price vs 50-DMAAbove
  • Price vs 200-DMAAbove
  • RSI (14)65.49 · Neutral
Price Performance
1M+13.55%
3M+128.67%
6M+184.40%
1Y+319.46%
Valuation vs Sector

P/E of 24.46 is below the sector median of 25.17 — relatively cheaper than peers.

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Strong return on equity of 29.5%.
  • Excellent profit margin of 24.2%.
  • Compounding revenue at 25.2% over 5 years.
  • Generates positive free cash flow.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
24.46
Industry PE
25.17
Forward P/E
37.55
PEG Ratio
-
Book Value
$8.27
Price to Book
5.65
P/S
5.27
EV/EBITDA
165.78
Dividend Yield
0.00%

Growth (CAGR)

Revenue 5Y
25.20%
Profit 5Y
-
Revenue (YoY)
52.20%
Earnings (YoY)
-140.64%

Profitability & Returns

ROCE
-9.52%
ROE
29.49%
ROA
-0.25%
Profit Margin
24.23%
Op Margin
0.19%
Gross Margin
70.58%
EPS (Latest Qtr)
$2.07
EPS (TTM)
$2.08

Balance Sheet & Liquidity

Debt/Equity
4.52
Quick Ratio
4.36
Current Ratio
4.58
Debt
$19.25M
Total Assets
$532.99M
Current Assets
-
Working Capital
-

Ownership

Promoter Holding
3.16%
Chg in Prom Hold
-0.10%
FII / Inst Holding
103.45%
Chg in FII Hold
0.03%

Financial Snapshot

Enterprise Value
$2.63B
Total Revenue (TTM)
$458.09M
EBITDA
$12.43M
Free Cash Flow
$112.16M
Operating Cash Flow
$93.66M
Shares Outstanding
51.73M
Gross Margin
70.58%
Payout Ratio
0.00%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 CDNA CareDx, Inc. R2KR3KPHARMA 50.88 24.46 $2.63B 0.00% -9.52% 29.49% 25.20% -
2 LLY Eli Lilly and Company SPXR3KPHARMA 1,149.36 38.57 $1.02T 0.58% - 102.29% 7.20% 11.41%
3 JNJ Johnson & Johnson SPXR3KPHARMA 275.23 31.97 $663.28B 2.09% 14.88% 25.74% 2.43% 4.76%
4 ABBV AbbVie Inc. SPXR3KPHARMA 256.46 72.45 $453.19B 2.84% 10.47% -129.24% 1.75% -29.06%
5 MRK Merck & Co., Inc. SPXR3KPHARMA 150.33 120.26 $371.29B 2.65% - 34.70% 5.64% 10.01%
6 UNH UnitedHealth Group Incorporated SPXR3KPHARMA 397.14 25.54 $356.47B 2.33% 9.74% 14.15% 10.40% 5.43%
7 NVS Novartis AG PHARMA 159.99 24.20 $304.10B 3.03% 21.09% 30.35% 9.25% 26.22%
8 AZN AstraZeneca PLC NDXPHARMA 162.70 24.36 $252.33B 1.98% 15.97% 21.96% 9.82% 45.96%
9 AMGN Amgen Inc. NDXSPXR3KPHARMA 437.23 27.14 $235.98B 2.49% 13.95% 91.47% 5.51% 5.55%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Mar 2025Jun 2025Sep 2025Mar 2026Jun 2026
Revenue --------11.58M12.05M12.19M12.50M14.05M17.82M21.18M23.51M25.98M31.45M33.81M35.82M38.38M41.80M53.37M67.40M74.19M75.59M79.42M80.63M79.36M77.26M70.30M67.19M72.05M92.27M82.88M84.69M86.68M100.06M117.70M131.95M
Gross Profit -------------10.62M12.30M-16.25M19.94M22.32M-25.99M26.78M------------------
Operating Income -1.39M-2.89M-3.19M--6.57M-6.97M-4.93M--8.54M-3.60M-3.86M--5.24M-5.21M-2.72M--5.40M-6.84M-6.75M--5.75M-10.80M-2.91M-858.00K-4.74M-8.73M-19.05M-21.72M-17.34M-24.32M-27.62M-28.78M-22.57M-7.33M-13.72M-13.37M-11.12M-246.00K1.20M113.22M
Net Income -2.27M-3.19M-3.49M-4.76M-9.75M-10.47M-3.76M-15.48M-5.56M-3.97M-14.27M-31.67M-8.97M-14.06M-19.97M-3.75M-7.53M-7.85M-1.81M-4.78M-5.82M-6.56M-2.82M-687.00K-1.93M-11.90M-19.65M-21.70M-16.94M-23.75M-24.95M-23.48M-19.89M-4.62M-10.64M-10.35M-8.57M1.68M2.81M110.64M
Diluted EPS -0.19-0.27-0.29-0.40-0.81-0.77-0.26-0.73-0.26-0.19-0.63-1.13-0.30-0.40-0.54-0.09-0.18-0.19-0.04-0.11-0.14-0.15-0.06-0.01-0.04-0.23-0.37-0.41-0.32-0.44-0.46-0.43-0.38-0.09-0.20-0.19-0.160.030.052.07
R&D Expense 1.42M2.51M2.70M-3.16M3.14M2.93M-3.28M3.12M2.96M-3.37M3.50M3.87M-5.61M7.63M8.52M-10.01M13.13M12.47M16.00M19.04M19.44M21.88M22.63M22.31M24.36M20.23M19.00M18.71M19.69M17.49M18.52M16.83M16.77M21.42M22.38M

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue 20.45M22.10M27.31M28.14M40.63M48.32M76.57M127.07M192.19M296.40M321.79M280.32M333.79M379.81M
Gross Profit -----26.95M43.58M81.61M------
Operating Income -2.34M-857.00K1.25M-11.93M-37.33M-20.29M-15.58M-24.53M-22.53M-29.73M-77.23M-203.36M40.77M-30.78M
Net Income -5.06M-3.54M781.00K-13.71M-39.47M-55.47M-46.76M-21.97M-18.71M-30.66M-76.61M-190.28M52.55M-21.35M
Diluted EPS -5.01-3.500.10-1.16-2.39-2.38-1.31-0.52-0.40-0.59-1.44-3.540.93-0.40
R&D Expense 4.75M3.18M3.85M9.33M12.38M12.39M14.51M30.71M48.94M76.53M90.39M82.42M72.51M71.43M

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2011Dec 2012Dec 2013Dec 2014Mar 2015Jun 2015Sep 2015Dec 2015Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --9.87M61.14M63.28M61.37M59.34M55.64M48.83M100.45M102.09M76.73M80.32M77.74M75.09M83.56M130.70M151.74M368.51M566.62M542.99M466.83M491.05M413.23M
Total Equity -142.22M-147.20M-150.67M41.30M---29.49M---19.48M----6.13M95.93M99.00M277.68M465.88M430.91M261.33M378.43M303.10M
Cash & Equivalents 2.36M5.83M5.13M36.43M---29.89M---17.26M---16.89M64.62M38.22M134.67M348.49M89.92M82.20M114.69M65.43M
Long Term Debt --10.91M5.45M14.61M13.39M12.12M12.89M11.37M10.07M8.50M1.10M0021.17M18.34M000-----
Total Liabilities --25.34M19.84M---26.14M---56.97M---89.52M34.77M52.74M90.83M100.75M112.08M205.50M112.62M110.13M
Current Liabilities --7.59M11.13M---10.15M---40.83M---42.91M19.50M34.83M69.22M77.30M75.97M78.07M89.37M89.85M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -----16.52M-14.31M-4.01M-2.77M33.43M-19.29M-25.24M-18.39M38.05M42.03M
Investing Cash Flow -----21.12M-6.11M-7.93M-22.58M-100.39M47.71M-228.50M40.45M-483.00K2.16M
Financing Cash Flow ----24.93M29.38M50.27M-132.00K163.15M185.64M-4.54M-29.61M-5.61M-93.39M
Capital Expenditure -141.00K-98.00K-733.00K-1.20M-549.00K-186.00K-2.04M-------
Free Cash Flow -----17.07M-14.49M-6.04M-------
Share Buybacks --------00642.00K27.54M522.00K87.77M

Ratios (Annual)

Figures in %.

Metric Dec 2012Dec 2013Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----55.8%56.9%64.2%------
Operating Margin % -11.5%-3.9%4.6%-42.4%-91.9%-42.0%-20.3%-19.3%-11.7%-10.0%-24.0%-72.5%12.2%-8.1%
Net Margin % -24.7%-16.0%2.9%-48.7%-97.1%-114.8%-61.1%-17.3%-9.7%-10.3%-23.8%-67.9%15.7%-5.6%
ROE % 3.4%2.4%1.9%-46.5%-202.6%904.3%-48.7%-22.2%-6.7%-6.6%-17.8%-72.8%13.9%-7.0%
ROCE % --37.6%2.5%-26.2%-104.0%-49.9%-14.0%-21.0%-7.5%-6.1%-16.5%-52.3%10.1%-9.5%

Shareholding Pattern

Insiders
3.16%
Institutions
103.45%
Public Float
106.82%

Top Institutional Holders

#Holder% HeldSharesValue
1 Blackrock Inc. 9.31% 4.81M $239.72M
2 State Street Corporation 4.77% 2.47M $122.92M
3 Vanguard Capital Management LLC 4.25% 2.20M $109.41M
4 Deerfield Management Company, L.P 3.86% 2.00M $99.46M
5 ARK Investment Management, LLC 3.78% 1.95M $97.27M
6 Boston Partners 3.75% 1.94M $96.47M
7 BAMCO Inc. 3.74% 1.94M $96.46M
8 Gagnon Securities, LLC 3.42% 1.77M $88.16M
9 Chevy Chase Trust Holdings, LLC 2.78% 1.44M $71.57M
10 Geode Capital Management, LLC 2.57% 1.33M $66.12M

Analyst View

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Latest News

Recent headlines for CDNA

Google News Mon, 07 Sep 2026

CareDx (CDNA) Rallies On Transplant Growth Narrative But Is The Valuation Still Compelling - simplywall.st

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Google News Sun, 23 Aug 2026

CareDx (CDNA) Shares Jumped, So What Is Driving Attention Now? - Yahoo Finance

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Google News Mon, 17 Aug 2026

CareDx (NASDAQ: CDNA) insider lines up $423K stock sale - Stock Titan

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Google News Sat, 05 Sep 2026

Technical Reactions to CDNA Trends in Macro Strategies - Stock Traders Daily

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Google News ue, 28 Apr 2026

CareDx (NASDAQ:CDNA) Beats Q1 Estimates and Raises Full-Year Guidance, But Stock Slips - ChartMill

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Google News hu, 27 Aug 2026

CareDx (CDNA) is a Great Momentum Stock: Should You Buy? - Eastern Progress

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CDNA — Frequently Asked Questions

What is the current share price of CareDx, Inc. (CDNA)?

As of 2026-09-07 16:24 PDT, CareDx, Inc. (CDNA) trades at $50.88 on NasdaqGM. Its 52-week range is $11.57 to $52.36.

What is the market capitalisation of CDNA?

CareDx, Inc. (CDNA) has a market capitalisation of $2.63B on NasdaqGM.

What is the P/E ratio of CDNA?

CDNA trades at a trailing price-to-earnings (P/E) ratio of 24.46. The industry average P/E is 25.17. Its price-to-book (P/B) ratio is 5.65.

What is the return on equity (ROE) of CDNA?

CDNA has a return on equity (ROE) of 29.49%. Its return on capital employed (ROCE) is -9.52%.

Is CDNA a good stock to buy?

This page provides a data-driven analysis of CareDx, Inc. (CDNA), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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