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AstraZeneca PLC AZN NDX

Healthcare · Drug Manufacturers - General · United Kingdom
https://www.astrazeneca.com
Company Profile ↓
$164.50
+16.65% 1Y
Mkt Cap$255.12B
P/E24.81
P/B5.85
Div. Yield1.77%
52W High$208.62
52W Low$135.08
Book Value$30.56
EPS (TTM)$6.63

Company Overview

AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company offers Imjudo, Datroway, Iressa, Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Crestor, Andexxa, Onglyza, Symlin, XIGDUO XR, Atacand, Atacand HCT, Atacand Plus, Farxiga/Forxiga, Plendil, Modip, Splendil, Munobal, Flodil, Tenormin, Tenormine, Prenormine, Atenol, Zestril, Brilinta/Brilique, Komboglyze, Qtern, Wainua, Byetta, Lokelma, Seloken ZOK, Toprol-XL, Betaloc ZOK, XIGDUO, Accolate, Accoleit, Vanticon, Bricanyl Respules, Eklira Genuair/Tudorza/Bretaris, Pulmicort Turbuhaler, Symbicort Turbuhaler, Airsupra, Bricanyl Turbuhaler, Fasenra, Rhinocort, Tezspire, Bevespi Aerosphere, Daliresp/Daxas, Oxis Turbuhaler, Saphnelo, Breztri Aerosphere, Duaklir Genuair, Pulmicort Respules, and Symbicort pMDI. It also provides Beyfortus, Kavigale, Evusheld, Fluenz/FluMist, Synagis, Kanuma, Ultomiris, Koselugo, Voydeya, Soliris, Strensiq, Nexium, and other medicines. The company offers its products for ocology, cardiovascular, renal and metabolism, respiratory & immunology, vaccines and immune, and therapies rare diseases. It serves primary and specialty care physicians through distributors and local representative offices in the United Kingdom, the Americas, rest of Europe, Asia, Africa, and Australasia. It has a strategic agreement with Tempus and Pathos to develop the largest multimodal foundation model in oncology; CSPC Pharmaceutical Group Limited to advance the discovery and development of novel oral candidates, with the potential to treat diseases across multiple indications; and Nucs AI Inc. to develop AI-driven Response Prediction for Therapeutic Radioconjugates. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.

Why Investors Should Care

Strong Return on Equity

Generates a return on equity of 23.5%, reflecting efficient use of shareholder capital.

Healthy Capital Returns

Return on capital employed stands at 16.0%.

Consistent Profit Growth

Net profit has compounded at 46.0% per year over the last five years.

Reasonable Valuation

Trades at a P/E of 24.8, below the sector median of 25.4.

Healthy Margins

Maintains a net profit margin of 17.2%.

Positive Free Cash Flow

Generates positive free cash flow, funding growth and shareholder returns internally.

Recent Developments

  • Dec 2025 Revenue of $58.74B (+8.6% YoY); net profit $10.22B.
  • Trailing 12 Months Year-on-year growth — revenue +12.5%, earnings +5.3%.
  • 5-Year Trend Long-term compounding — revenue CAGR 9.8%, profit CAGR 46.0%.

Growth & Price Performance

Compounded Sales Growth

5 Years:9.82%
1 Year:12.50%

Compounded Profit Growth

5 Years:45.96%
1 Year:5.30%

Stock Price Performance

1 Year:+16.65%
6 Months:-12.19%
3 Months:-18.66%
1 Month:-9.75%

Highlights auto-generated from reported financials and price data; not investment advice. Verify with official filings before acting.

Technical Snapshot Bearish
52-Week Range 40% of range
$135.08 $208.62
Trend Signals
  • Price vs 50-DMABelow
  • Price vs 200-DMABelow
  • Death Cross2d ago
  • RSI (14)33.73 · Neutral
Price Performance
1M-9.75%
3M-18.66%
6M-12.19%
1Y+16.65%
Valuation vs Sector

P/E of 24.81 is below the sector median of 25.41 — relatively cheaper than peers.

Auto-generated from price history and fundamentals; not investment advice.

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Price Chart

Robinhood TradingView

Fundamental Growth Charts

Interactive charts for Revenue, Net Income, EBITDA, Free Cash Flow, EPS, ROE, ROCE, Gross/Net/Operating Margin and more — switch metric and period using the dropdowns above. CAGR is computed across the displayed window (quarterly CAGR is annualised). Visual growth charts make it easy to spot multi-year compounding trends at a glance — far faster than reading raw numbers in a table.

PROS

  • Strong return on equity of 23.5%.
  • Profit CAGR of 46.0% over 5 years.
  • Generates positive free cash flow.

CONS

  • In a downtrend (50-DMA below 200-DMA).

* The pros and cons are auto-generated from financial metrics.

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Valuation

Stock P/E
24.81
Industry PE
25.41
Forward P/E
20.45
PEG Ratio
1.37
Book Value
$30.56
Price to Book
5.85
P/S
4.59
EV/EBITDA
15.14
Dividend Yield
1.77%

Growth (CAGR)

Revenue 5Y
9.82%
Profit 5Y
45.96%
Revenue (YoY)
12.50%
Earnings (YoY)
5.30%

Profitability & Returns

ROCE
15.97%
ROE
23.48%
ROA
8.49%
Profit Margin
17.19%
Op Margin
27.94%
Gross Margin
81.50%
EPS (Latest Qtr)
$1.97
EPS (TTM)
$6.63

Balance Sheet & Liquidity

Debt/Equity
0.72
Quick Ratio
0.70
Current Ratio
0.91
Debt
$34.03B
Total Assets
$114.02B
Current Assets
$29.61B
Working Capital
$-1.89B

Ownership

Promoter Holding
0.05%
Chg in Prom Hold
-
FII / Inst Holding
68.25%
Chg in FII Hold
-

Financial Snapshot

Enterprise Value
$255.12B
Total Revenue (TTM)
$60.44B
EBITDA
$20.03B
Free Cash Flow
$6.56B
Operating Cash Flow
$14.22B
Shares Outstanding
1.55B
Gross Margin
81.50%
Payout Ratio
47.70%

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 AZN AstraZeneca PLC NDX 164.50 24.81 $255.12B 1.77% 15.97% 23.48% 9.82% 45.96%
2 LLY Eli Lilly and Company SPX 1,152.54 41.02 $1.03T 0.61% - 107.46% 7.20% 11.41%
3 JNJ Johnson & Johnson SPX 253.85 29.45 $611.07B 2.23% 14.88% 26.42% 2.43% 4.76%
4 ABBV AbbVie Inc. SPX 244.78 119.40 $432.48B 3.04% 10.47% -129.24% 1.75% -29.06%
5 UNH UnitedHealth Group Incorporated SPX 425.19 32.02 $386.13B 2.27% 9.74% 12.18% 10.40% 5.43%
6 MRK Merck & Co., Inc. SPX 120.78 34.02 $298.31B 2.86% - 18.94% 5.64% 10.01%
7 TMO Thermo Fisher Scientific Inc. SPX 534.07 29.33 $198.47B 0.40% 8.14% 13.52% 8.81% 12.95%
8 AMGN Amgen Inc. NDXSPX 355.25 24.69 $191.73B 2.84% 18.02% 101.32% 11.77% 5.58%
9 GILD Gilead Sciences, Inc. NDXSPX 130.04 17.69 $161.45B 2.61% 21.23% 43.36% 11.38% 9.79%
Financial Statements Quarterly Results · Profit & Loss · Balance Sheet · Cash Flows · Ratios

Quarterly Results

Figures in USD.

Metric Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue -13.59B14.46B15.19B15.50B15.29B
Cost of Revenue -2.24B2.47B2.80B3.12B2.68B
Gross Profit -11.35B11.98B12.39B12.38B12.61B
Operating Expenses -7.67B8.48B8.81B9.41B8.36B
Operating Income -3.67B3.51B3.58B2.98B4.25B
EBITDA -5.04B4.96B5.23B4.38B5.67B
Interest Expense -349.00M439.00M434.00M484.00M393.00M
Pretax Income -3.40B3.13B3.24B2.63B3.91B
Tax Provision -481.00M679.00M709.00M300.00M833.00M
Net Income -2.92B2.45B2.53B2.33B3.08B
Diluted EPS 0.961.871.57-1.491.97

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue -44.35B45.81B54.07B58.74B
Cost of Revenue -12.39B8.27B10.21B10.63B
Gross Profit -31.96B37.54B43.87B48.11B
Operating Expenses -27.45B28.82B33.62B34.78B
Operating Income -4.51B8.72B10.25B13.33B
EBITDA -9.09B13.42B15.44B19.51B
Interest Expense -1.33B1.59B1.68B1.61B
Pretax Income -2.50B6.90B8.69B12.40B
Tax Provision --792.00M938.00M1.65B2.17B
Net Income -3.29B5.96B7.04B10.22B
Diluted EPS -2.113.814.506.54

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets -96.48B101.12B104.03B114.07B
Current Assets -22.59B25.05B25.83B28.72B
Cash & Equivalents -6.17B5.84B5.49B5.71B
Inventory -4.70B5.42B5.29B6.56B
Receivables -7.21B8.41B8.30B10.24B
Total Liabilities -59.42B61.95B63.16B65.36B
Current Liabilities -26.29B30.54B27.87B30.62B
Long Term Debt -22.96B22.36B26.51B24.71B
Total Debt -29.14B28.41B30.11B29.15B
Total Equity -37.04B39.14B40.79B48.67B
Shares Outstanding -1.55B1.55B1.55B1.55B

Cash Flows (Annual)

Figures in USD.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -9.81B10.35B11.86B14.57B
Investing Cash Flow --2.96B-4.06B-7.98B-6.81B
Financing Cash Flow --6.82B-6.57B-4.00B-7.54B
Capital Expenditure --2.57B-3.78B-4.59B-5.91B
Free Cash Flow -7.24B6.57B7.28B8.67B
Net Change in Cash -25.00M-286.00M-115.00M223.00M

Ratios (Annual)

Figures in %.

Metric Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -72.1%82.0%81.1%81.9%
Operating Margin % -10.2%19.0%19.0%22.7%
Net Margin % -7.4%13.0%13.0%17.4%
ROE % -8.9%15.2%17.2%21.0%
ROCE % -6.4%12.4%13.5%16.0%

Shareholding Pattern

Insiders
0.05%
Institutions
68.25%
Public Float
68.28%

Top Institutional Holders

#Holder% HeldSharesValue
1 Investor AB 3.33% 51.59M $9.69B
2 Vanguard Capital Management LLC 2.90% 45.04M $8.46B
3 Capital International Investors 2.22% 34.39M $6.46B
4 FMR, LLC 1.91% 29.60M $5.56B
5 Capital World Investors 1.82% 28.26M $5.31B
6 Legal & General Group PLC 1.67% 25.85M $4.85B
7 Wellington Management Group, LLP 1.53% 23.75M $4.46B
8 Price (T.Rowe) Associates Inc 1.26% 19.49M $3.66B
9 Bank of America Corporation 1.23% 19.06M $3.58B
10 JPMORGAN CHASE & CO 1.20% 18.59M $3.49B

Analyst View

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Latest News

Recent headlines for AZN

Yahoo Finance ue, 14 Jul 2026

AstraZeneca pays up to $1.5bn to license Dizal Pharma’s lung cancer drug

In licensing Zegfrovy, AstraZeneca has gained an already approved asset, with a label expansion potentially on the horizon.

Yahoo Finance ue, 14 Jul 2026

Here's How Pfizer's Oncology Growth Story Looks Ahead of Q2 Results

PFE's oncology business is in focus ahead of Q2 results as growth from key cancer drugs, biosimilars and pipeline updates may offset declines in older therapies.

Yahoo Finance ue, 14 Jul 2026

Amivantamab Lazertinib Forecast to Lead US EGFR NSCLC Therapy Revenue by 2036 as Post-TAGRISSO Competition Intensifies

Across the US, EU4, UK and Japan, opportunities center on post-osimertinib resistance, CNS disease and rare EGFR mutations; ADCs, bispecifics and next-gen TKIs face crowded competition.Dublin, July 14, 2026 (GLOBE NEWSWIRE) -- The "Epiderma…

Yahoo Finance ue, 14 Jul 2026

Advancements in CKD Care: How New Therapies from AstraZeneca, Johnson & Johnson, Novartis, Bayer, and Amgen Are Changing the Landscape

Opportunities include integrating cardio-renal strategies, aligning therapies with real-world evidence, leveraging site-of-care economics, and enhancing supply resilience amid tariff influences. Late Stage Chronic Kidney Disease Therapeutic…

Yahoo Finance ue, 14 Jul 2026

AstraZeneca to pay up to $1.5bn for global rights to lung cancer pill

AstraZeneca PLC (LSE:AZN, NASDAQ:AZN) has agreed to pay $600 million upfront to secure worldwide rights to a lung cancer pill developed by China's Dizal Pharmaceutical. The Cambridge-based drugmaker could pay a further $900 million if the t…

Yahoo Finance ue, 14 Jul 2026

Dizal Announces Global Exclusive License Agreement with AstraZeneca for Zegfrovy

Today, Dizal announced that it has entered into a global exclusive license agreement with AstraZeneca for Zegfrovy (sunvozertinib), a novel oral irreversible epidermal growth factor receptor (EGFR) inhibitor for patients with lung cancer. A…

AZN — Frequently Asked Questions

What is the current share price of AstraZeneca PLC (AZN)?

As of 2026-07-14 21:23 PDT, AstraZeneca PLC (AZN) trades at $164.50 on NYSE. Its 52-week range is $135.08 to $208.62.

What is the market capitalisation of AZN?

AstraZeneca PLC (AZN) has a market capitalisation of $255.12B on NYSE.

What is the P/E ratio of AZN?

AZN trades at a trailing price-to-earnings (P/E) ratio of 24.81. The industry average P/E is 25.41. Its price-to-book (P/B) ratio is 5.85.

Does AZN pay a dividend?

AstraZeneca PLC (AZN) currently offers a dividend yield of 1.77%.

What is the return on equity (ROE) of AZN?

AZN has a return on equity (ROE) of 23.48%. Its return on capital employed (ROCE) is 15.97%.

Is AZN a good stock to buy?

This page provides a data-driven analysis of AstraZeneca PLC (AZN), including valuation ratios, profitability, growth trends, auto-generated pros and cons, peer comparison and AI exposure. Review these fundamentals alongside your own research and risk tolerance. This is informational content, not investment advice.

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