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AnaptysBio, Inc. ANAB R2K

Healthcare · Biotechnology · United States
https://www.anaptysbio.com

AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States. The company's products include Rosnilimab, a selective pathogenic T cell deplete which completed a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis; ANB033, a CD122 antagonist, which is in a Phase 1b trial for celiac disease and eosinophilic esophagitis; ANB101, a BDCA2 modulator antibody which is in Phase 1a trial that specifically targets plasmacytoid dendritic cells and inhibits interferon secretion and modulates antigen presentation; dostarlimab, a PD-1 antagonist for various solid tumor indications; and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. It focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has collaborations agreement with GSK and Vanda. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

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$55.67
+275.64% 1Y

Market & Price

Market Cap
$1.62B
Current Price
$55.67
High / Low (52W)
$69.78 / $12.93
Beta
0.48

Valuation

Stock P/E
-
Industry PE
23.65
Forward P/E
9.55
PEG Ratio
-
Book Value
$0.44
Price to Book
126.81
P/S
6.97
EV/EBITDA
38.97
Dividend Yield
-

Profitability & Returns

ROCE
20.51%
ROE
-114.55%
ROA
6.78%
Profit Margin
-11.53%
Op Margin
-
EPS (Latest Qtr)
$-1.84
EPS (TTM)
$-1.02

Balance Sheet & Liquidity

Debt/Equity
21.76
Quick Ratio
7.49
Current Ratio
7.58
Debt
$277.36M
Total Assets
$364.39M
Current Assets
$350.25M
Working Capital
$311.62M

Ownership

Promoter Holding
5.74%
Chg in Prom Hold
0.00%
FII / Inst Holding
103.58%
Chg in FII Hold
0.02%

Financial Snapshot

Enterprise Value
$1.61B
Total Revenue (TTM)
$232.39M
EBITDA
$41.34M
Free Cash Flow
$8.32M
Operating Cash Flow
$4.48M
Shares Outstanding
29.10M
Gross Margin
44.58%
Payout Ratio
0.00%

Growth (CAGR)

Revenue 5Y
183.58%
Profit 5Y
29.91%
Revenue (YoY)
-8.00%
Earnings (YoY)
-

PROS

  • Healthy ROCE of 20.5%.
  • Compounding revenue at 183.6% over 5 years.
  • Profit CAGR of 29.9% over 5 years.
  • Generates positive free cash flow.
  • In a confirmed uptrend (50-DMA above 200-DMA).

CONS

No notable concerns flagged.

* The pros and cons are auto-generated from financial metrics.

Price Chart

Robinhood TradingView StockAnalysis

Fundamental Growth

Figures from the latest reported periods. CAGR is computed across the displayed window (quarterly CAGR is annualised assuming 4 quarters per year).

Peer comparison

Peer companies in the same sector (Healthcare).

#NameCMP $P/E Mkt CapDiv Yld % ROCE %ROE % Rev CAGR 5Y %Profit CAGR 5Y %
1 ANAB AnaptysBio, Inc. R2K 55.67 - $1.62B - 20.51% -114.55% 183.58% 29.91%
2 LLY Eli Lilly and Company SPX 1,105.00 39.21 $985.37B 0.63% 38.44% 107.46% 31.69% 48.96%
3 JNJ Johnson & Johnson SPX 225.33 26.11 $542.42B 2.38% 23.13% 26.42% 5.60% 14.32%
4 UNH UnitedHealth Group Incorporated SPX 380.31 28.66 $345.38B 2.32% 9.60% 12.18% 11.35% -15.69%
5 MRK Merck & Co., Inc. SPX 118.72 33.44 $293.22B 2.86% 20.66% 18.94% 3.12% 7.93%
6 TMO Thermo Fisher Scientific Inc. SPX 492.51 27.11 $183.03B 0.38% 9.17% 13.52% -0.27% -1.19%
7 AMGN Amgen Inc. NDXSPX 336.79 23.42 $181.77B 2.99% 18.02% 101.32% 11.77% 5.58%
8 GILD Gilead Sciences, Inc. NDXSPX 134.43 18.29 $166.90B 2.44% 22.92% 43.36% 2.57% 22.83%
9 ISRG Intuitive Surgical, Inc. NDXSPXAI 424.64 51.53 $150.39B - 15.96% 17.23% 17.39% 29.26%
Ad space

Quarterly Results

Figures in USD.

Metric Mar 2016Jun 2016Sep 2016Dec 2016Mar 2017Jun 2017Sep 2017Dec 2017Mar 2018Jun 2018Sep 2018Dec 2018Mar 2019Jun 2019Sep 2019Dec 2019Mar 2020Jun 2020Sep 2020Mar 2021Jun 2021Sep 2021Mar 2022Jun 2022Sep 2022Mar 2023Jun 2023Sep 2023Mar 2024Jun 2024Sep 2024Dec 2024Mar 2025Jun 2025Sep 2025Dec 2025Mar 2026
Revenue ---------05.00M-05.00M0-15.00M0011.25M30.03M20.89M970.00K1.22M1.29M1.37M3.46M3.32M7.18M10.97M30.02M-27.77M22.26M76.32M108.25M25.56M
Cost of Revenue -------------------------------------
Gross Profit -------------------------------------
Operating Expenses --------------------------------55.31M48.43M41.62M41.35M60.19M
Operating Income -1.14M2.36M-1.07M-3.17M-9.99M-2.56M-9.09M-7.15M-15.76M-14.41M-16.89M-19.66M-24.77M-26.66M-33.74M-22.26M-10.25M-22.64M-24.34M-18.36M-533.00K-6.76M-31.75M-27.80M-29.63M-44.40M-40.14M-37.73M-42.20M-40.32M-22.76M--27.54M-26.17M34.70M66.90M-34.64M
EBITDA ---------------------------------20.62M-18.38M38.24M70.01M-31.38M
Interest Expense --------------------------------18.06M19.61M22.52M19.71M20.86M
Pretax Income ---------------------------------39.28M-38.59M15.11M49.70M-52.84M
Tax Provision --------------------------------44.00K39.00K081.00K40.00K
Net Income -888.00K2.32M-1.11M--11.44M-2.68M-9.09M--15.09M-13.62M-15.96M--22.08M-23.96M-31.03M--8.26M-21.55M-23.77M-18.16M-429.00K-6.67M-36.26M-32.55M-33.50M-44.26M-39.84M-37.31M-43.94M-46.66M-32.85M--39.33M-38.63M15.11M49.61M-52.88M
Diluted EPS -0.340.05-0.42-1.73-0.75-0.13-0.45-0.30-0.63-0.57-0.66-0.64-0.82-0.89-1.15-0.75--0.79-0.87-0.66-0.02-0.24-1.31-1.15-1.18-1.58-1.50-1.41-1.64-1.71-1.14--1.28-1.340.521.58-1.84
R&D Expense 4.79M2.33M3.28M-7.93M7.21M6.70M-11.81M10.58M17.88M-20.63M27.35M29.93M-20.97M17.95M19.54M24.18M25.31M22.22M22.52M20.84M22.06M34.96M32.92M30.88M37.04M42.00M42.21M-41.18M37.82M31.41M--

Profit & Loss (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Revenue --10.00M5.00M8.00M75.00M63.17M10.29M17.16M91.28M234.60M
Cost of Revenue -----------
Gross Profit -----------
Operating Expenses -------125.44M174.23M206.23M186.71M
Operating Income -3.32M-3.02M-28.78M-66.72M-107.43M-23.88M-56.81M-115.15M-157.07M-114.95M47.90M
EBITDA --------105.26M-143.16M-92.74M69.25M
Interest Expense -------21.11M18.08M50.09M79.89M
Pretax Income --------128.70M-163.62M-145.23M-13.07M
Tax Provision -------24.00K-4.00K3.00K164.00K
Net Income -5.41M-4.26M-30.07M-61.66M-97.34M-19.93M-57.80M-128.72M-163.62M-145.23M-13.23M
Diluted EPS --1.62-1.52-2.50-3.60-0.73-2.11-4.57-6.08-5.12-0.46
R&D Expense 17.30M15.42M29.44M56.20M99.34M80.03M98.50M88.80M---

Compounded Sales Growth

5 Years:183.58%
1 Year:-8.00%

Compounded Profit Growth

5 Years:29.91%
1 Year:-

Stock Price Performance

1 Year:+275.64%
6 Months:+101.22%
3 Months:+51.69%
1 Month:-10.70%

Balance Sheet (Annual)

Figures in USD.

Metric Dec 2014Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Assets --62.18M329.36M509.00M435.20M416.55M-610.38M452.39M483.83M364.39M
Current Assets --------447.20M406.83M431.88M350.25M
Cash & Equivalents --51.23M81.19M113.60M171.02M250.46M-71.31M35.97M123.08M238.20M
Inventory ------------
Receivables --------1.42M6.85M40.77M33.85M
Total Liabilities --------348.28M364.29M412.97M327.19M
Current Liabilities --5.71M14.09M21.84M29.54M19.82M-26.05M37.44M45.43M38.62M
Long Term Debt ------------
Total Debt --------19.45M17.81M16.04M14.11M
Total Equity -30.84M-35.18M-38.25M307.58M486.37M405.01M396.73M-262.10M88.10M70.87M37.21M
Shares Outstanding --------28.51M26.60M30.47M28.02M

Cash Flows (Annual)

Figures in USD.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Operating Cash Flow -9.69M-9.03M-19.44M-48.51M-69.52M-14.16M--73.59M-120.80M-135.34M19.70M
Investing Cash Flow -238.00K-50.00K-243.06M-142.45M131.43M94.47M--394.85M144.75M95.40M228.03M
Financing Cash Flow 39.40M8.63M292.45M223.36M-4.49M-879.00K-44.02M-59.30M127.05M-132.61M
Capital Expenditure -238.00K-50.00K-290.00K-1.06M-805.00K-569.00K--358.00K-807.00K-358.00K-87.00K
Free Cash Flow -9.93M-9.08M-19.73M-49.57M-70.32M-14.73M--73.95M-121.61M-135.69M19.61M
Net Change in Cash --------424.42M-35.34M87.11M115.12M
Share Buybacks 01.00K00--0050.00M456.00K68.63M

Ratios (Annual)

Figures in %.

Metric Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Gross Margin % -----------
Operating Margin % ---287.8%-1,334.4%-1,342.9%-31.8%-89.9%-1,119.4%-915.5%-125.9%20.4%
Net Margin % ---300.7%-1,233.1%-1,216.7%-26.6%-91.5%-1,251.3%-953.7%-159.1%-5.6%
ROE % 15.4%11.1%-9.8%-12.7%-24.0%-5.0%--49.1%-185.7%-204.9%-35.6%
ROCE % --5.4%-9.1%-13.7%-26.5%-6.0%--19.7%-37.9%-26.2%14.7%

Shareholding Pattern

Insiders
5.74%
Institutions
103.58%
Public Float
109.89%

Top Institutional Holders

#Holder% HeldSharesValue
1 EcoR1 Capital, LLC 27.08% 7.88M $438.68M
2 Blackrock Inc. 5.78% 1.68M $93.60M
3 Tang Capital Management, LLC 4.57% 1.33M $74.09M
4 Morgan Stanley 3.42% 993.90K $55.33M
5 State Street Corporation 3.41% 992.45K $55.25M
6 Affinity Asset Advisors, Llc 3.23% 940.00K $52.33M
7 Vanguard Capital Management LLC 2.93% 853.15K $47.49M
8 Sanofi 2.82% 821.92K $45.76M
9 Palo Alto Investors Lp 2.19% 638.16K $35.53M
10 683 Capital Management LLC 2.15% 625.00K $34.79M

Analyst View

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